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The map label for this gene is modF [H]

Identifier: 238893789

GI number: 238893789

Start: 1658784

End: 1660268

Strand: Reverse

Name: modF [H]

Synonym: KP1_1718

Alternate gene names: 238893789

Gene position: 1660268-1658784 (Counterclockwise)

Preceding gene: 238893790

Following gene: 238893788

Centisome position: 31.63

GC content: 61.68

Gene sequence:

>1485_bases
ATGGGATACATCATGTCATCATTGCAAATTTCGCAAGGCACGTTTCGCCTGAGCGATACAAAGACCTTAAAAATAGACCA
CCTGAGCGTGGCGGCGGGTGAAAGCTGGGCGTTCGTCGGCAGCAACGGCAGCGGCAAATCCGCCCTCGCGCGAGCCCTGG
CCGGCGACCTGCCCCTGCTCAGCGGCCAGCGCGAAAGCCATTTCTCCCGCGTGACCCGCCTCTCCTTCGAACAGTTGCAG
AAGCTGGTCAGCGACGAGTGGCAGCGCAATAACACCGACCTGCTCAGCCCAGGCGAAGAAGACACCGGCCGCACCACCGC
GGAGATTATCCAGGATGAGGTGAAAGATCCTGCCCGCTGCGCGCGCCTGGCCGAACAATTTGGCATCAGCGCCCTGCTGG
ACCGCCGGTTTAAATACCTGTCGACCGGGGAAACGCGTAAGACCCTGCTGTGTCAGGCCCTGATGACCGATCCGCAACTG
CTGATCCTCGATGAACCTTTCGACGGTCTCGACGTCAACTCCCGCCAGCAGCTGGCTGCCCTGCTGGCCGACCTGCACAG
CGCTGGCATCACCCTGGTGCTGGTGCTCAACCGCTTCGATGAGATCCCGGAGTTTGTGCAATTCGCCGGCGTGCTGGCTG
ACTGCACCCTTAGCGAGACCGGCGAGAAGTCTTCCCTGCTGCAGCAGGCGCTGGTCGCCCAGCTGGCGCACAGTGAAAAA
CTGGACGGCATCACCCTGCCGGAGCCGGATGTCCCACCGGCCCGTCATGCGCTGGCAGACTCGGCGCCGCGTATCGTGCT
CAACGACGGCGTGGTCTCCTATAACGATCGCCCGGTCATCAATCACCTCTCATGGACCGTGAATCCGGGCGAACACTGGC
AGATCGTCGGTCCCAACGGCGCCGGTAAATCTACGCTGCTGAGCCTGGTCACCGGGGATCATCCGCAGGGCTACAGCAAC
GATCTCACGCTCTTTGGCCGCCGGCGCGGCAGCGGTGAGACCATCTGGGATATTAAAAAGCATATCGGCTACGTCAGCAG
CAGCCTGCATCTGGACTACCGGGTCAGCACCAACGTCCGCAACGTCATCCTGTCGGGCTATTTTGACTCGATCGGCATTT
ATCAGGCGGTCTCCGACAAGCAACACAAGCTGGTGCAGCAATGGCTGGATATTCTCGGCATCGATAAGCGCACCGCCGAC
GCGCCGTTTCACAGTCTGTCGTGGGGCCAGCAGCGGCTGGCGCTTATCGTCCGCGCGCTGGTGAAGCATCCAACCCTGCT
GATCCTCGATGAACCGCTGCAGGGGCTGGACCCCCTCAACCGCCAGCTGGTGCGCCGCTTTGTCGACGTGTTGATTGGCG
AAGGGGCCACACAGCTGCTGTTTGTCTCGCACCATGCGGAAGATGCCCCGGACTGCATTACCCATCGCCTGGCGTTCGTT
CCCAGTGGAGACGGTTACACTTATCAGCTCGGCCCCGTGGCCTGA

Upstream 100 bases:

>100_bases
GCTTACTTCAATGCCGATCGCATCATTCTCGCGACGTTATGCTGACCCCATTGACATTACGCGCCTGAAGTCGTATCCCT
GATGCACATCGCTGCAAAAA

Downstream 100 bases:

>100_bases
CGCCCCCTGCCGGGGATCGAAAGATCCCTGGTATTTTTCAGAAAAATAGCGCCAAACAAACCTAATACATTGAATTAAAA
TTAAAAATATAAAATTTACG

Product: putative molybdenum transport ATP-binding protein ModF

Products: NA

Alternate protein names: Photorepair protein PhrA [H]

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MGYIMSSLQISQGTFRLSDTKTLKIDHLSVAAGESWAFVGSNGSGKSALARALAGDLPLLSGQRESHFSRVTRLSFEQLQ
KLVSDEWQRNNTDLLSPGEEDTGRTTAEIIQDEVKDPARCARLAEQFGISALLDRRFKYLSTGETRKTLLCQALMTDPQL
LILDEPFDGLDVNSRQQLAALLADLHSAGITLVLVLNRFDEIPEFVQFAGVLADCTLSETGEKSSLLQQALVAQLAHSEK
LDGITLPEPDVPPARHALADSAPRIVLNDGVVSYNDRPVINHLSWTVNPGEHWQIVGPNGAGKSTLLSLVTGDHPQGYSN
DLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTNVRNVILSGYFDSIGIYQAVSDKQHKLVQQWLDILGIDKRTAD
APFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLIGEGATQLLFVSHHAEDAPDCITHRLAFV
PSGDGYTYQLGPVA

Sequences:

>Translated_494_residues
MGYIMSSLQISQGTFRLSDTKTLKIDHLSVAAGESWAFVGSNGSGKSALARALAGDLPLLSGQRESHFSRVTRLSFEQLQ
KLVSDEWQRNNTDLLSPGEEDTGRTTAEIIQDEVKDPARCARLAEQFGISALLDRRFKYLSTGETRKTLLCQALMTDPQL
LILDEPFDGLDVNSRQQLAALLADLHSAGITLVLVLNRFDEIPEFVQFAGVLADCTLSETGEKSSLLQQALVAQLAHSEK
LDGITLPEPDVPPARHALADSAPRIVLNDGVVSYNDRPVINHLSWTVNPGEHWQIVGPNGAGKSTLLSLVTGDHPQGYSN
DLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTNVRNVILSGYFDSIGIYQAVSDKQHKLVQQWLDILGIDKRTAD
APFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLIGEGATQLLFVSHHAEDAPDCITHRLAFV
PSGDGYTYQLGPVA
>Mature_493_residues
GYIMSSLQISQGTFRLSDTKTLKIDHLSVAAGESWAFVGSNGSGKSALARALAGDLPLLSGQRESHFSRVTRLSFEQLQK
LVSDEWQRNNTDLLSPGEEDTGRTTAEIIQDEVKDPARCARLAEQFGISALLDRRFKYLSTGETRKTLLCQALMTDPQLL
ILDEPFDGLDVNSRQQLAALLADLHSAGITLVLVLNRFDEIPEFVQFAGVLADCTLSETGEKSSLLQQALVAQLAHSEKL
DGITLPEPDVPPARHALADSAPRIVLNDGVVSYNDRPVINHLSWTVNPGEHWQIVGPNGAGKSTLLSLVTGDHPQGYSND
LTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTNVRNVILSGYFDSIGIYQAVSDKQHKLVQQWLDILGIDKRTADA
PFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLVRRFVDVLIGEGATQLLFVSHHAEDAPDCITHRLAFVP
SGDGYTYQLGPVA

Specific function: Involved in the transport of molybdenum into the cell. Involved in photorepair. Could act on UV-induced DNA damage other than pyrimidine dimers [H]

COG id: COG1119

COG function: function code P; ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI27262624, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=5e-11,
Organism=Homo sapiens, GI27262626, Length=206, Percent_Identity=26.6990291262136, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1786975, Length=489, Percent_Identity=85.8895705521472, Blast_Score=864, Evalue=0.0,
Organism=Escherichia coli, GI48994943, Length=376, Percent_Identity=26.3297872340426, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789991, Length=488, Percent_Identity=22.9508196721311, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI48995001, Length=467, Percent_Identity=25.0535331905782, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1790525, Length=480, Percent_Identity=22.2916666666667, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788897, Length=488, Percent_Identity=21.7213114754098, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788506, Length=509, Percent_Identity=25.9332023575639, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1787792, Length=469, Percent_Identity=24.7334754797441, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790190, Length=470, Percent_Identity=24.8936170212766, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87081782, Length=219, Percent_Identity=27.8538812785388, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI145693107, Length=526, Percent_Identity=23.7642585551331, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788165, Length=229, Percent_Identity=30.1310043668122, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786253, Length=201, Percent_Identity=32.3383084577114, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789593, Length=198, Percent_Identity=29.2929292929293, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786563, Length=223, Percent_Identity=28.6995515695067, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787029, Length=206, Percent_Identity=29.6116504854369, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786319, Length=210, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787112, Length=225, Percent_Identity=28.8888888888889, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1788225, Length=227, Percent_Identity=25.5506607929515, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1790544, Length=184, Percent_Identity=29.8913043478261, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789864, Length=217, Percent_Identity=25.3456221198157, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788472, Length=468, Percent_Identity=21.5811965811966, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1790739, Length=237, Percent_Identity=27.8481012658228, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115533608, Length=302, Percent_Identity=24.8344370860927, Blast_Score=65, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6320266, Length=400, Percent_Identity=29, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI221512771, Length=220, Percent_Identity=26.8181818181818, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24650853, Length=211, Percent_Identity=30.3317535545024, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24650855, Length=211, Percent_Identity=30.3317535545024, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281362751, Length=211, Percent_Identity=30.3317535545024, Blast_Score=70, Evalue=5e-12,
Organism=Drosophila melanogaster, GI28574744, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 54314; Mature: 54183

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYIMSSLQISQGTFRLSDTKTLKIDHLSVAAGESWAFVGSNGSGKSALARALAGDLPLL
CCCCCCCEEECCCEEEECCCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCC
SGQRESHFSRVTRLSFEQLQKLVSDEWQRNNTDLLSPGEEDTGRTTAEIIQDEVKDPARC
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHH
ARLAEQFGISALLDRRFKYLSTGETRKTLLCQALMTDPQLLILDEPFDGLDVNSRQQLAA
HHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHH
LLADLHSAGITLVLVLNRFDEIPEFVQFAGVLADCTLSETGEKSSLLQQALVAQLAHSEK
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHC
LDGITLPEPDVPPARHALADSAPRIVLNDGVVSYNDRPVINHLSWTVNPGEHWQIVGPNG
CCCCCCCCCCCCHHHHHHHCCCCEEEEECCEEECCCCCEEEEEEEEECCCCCEEEECCCC
AGKSTLLSLVTGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTNVR
CCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEECCCHH
NVILSGYFDSIGIYQAVSDKQHKLVQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRAL
HHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VKHPTLLILDEPLQGLDPLNRQLVRRFVDVLIGEGATQLLFVSHHAEDAPDCITHRLAFV
HHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHEEEE
PSGDGYTYQLGPVA
ECCCCEEEECCCCC
>Mature Secondary Structure 
GYIMSSLQISQGTFRLSDTKTLKIDHLSVAAGESWAFVGSNGSGKSALARALAGDLPLL
CCCCCCEEECCCEEEECCCCEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHCCCCCC
SGQRESHFSRVTRLSFEQLQKLVSDEWQRNNTDLLSPGEEDTGRTTAEIIQDEVKDPARC
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHH
ARLAEQFGISALLDRRFKYLSTGETRKTLLCQALMTDPQLLILDEPFDGLDVNSRQQLAA
HHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCHHHHHH
LLADLHSAGITLVLVLNRFDEIPEFVQFAGVLADCTLSETGEKSSLLQQALVAQLAHSEK
HHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHC
LDGITLPEPDVPPARHALADSAPRIVLNDGVVSYNDRPVINHLSWTVNPGEHWQIVGPNG
CCCCCCCCCCCCHHHHHHHCCCCEEEEECCEEECCCCCEEEEEEEEECCCCCEEEECCCC
AGKSTLLSLVTGDHPQGYSNDLTLFGRRRGSGETIWDIKKHIGYVSSSLHLDYRVSTNVR
CCHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCEEEEEEECCCHH
NVILSGYFDSIGIYQAVSDKQHKLVQQWLDILGIDKRTADAPFHSLSWGQQRLALIVRAL
HHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
VKHPTLLILDEPLQGLDPLNRQLVRRFVDVLIGEGATQLLFVSHHAEDAPDCITHRLAFV
HHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHEEEE
PSGDGYTYQLGPVA
ECCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8564363; 8550508; 8905232; 9278503; 8310005 [H]