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The map label for this gene is pnuC [H]

Identifier: 238893780

GI number: 238893780

Start: 1649686

End: 1650405

Strand: Direct

Name: pnuC [H]

Synonym: KP1_1707

Alternate gene names: 238893780

Gene position: 1649686-1650405 (Clockwise)

Preceding gene: 238893779

Following gene: 238893783

Centisome position: 31.43

GC content: 55.14

Gene sequence:

>720_bases
ATGGATTTTTTTAGCACGCAGAATATTTTAGTACATATACCCATCGGCGCTGGGGGGTACGATCTCTCCTGGATAGAGGC
CGTGGGGACGATTGCCGGGCTGTTGTGTATCTGGCTGGCGAGCCTGGAGAAGATCAGTAACTATGCTTTCGGGCTGGTCA
ACGTCACGCTGTTCGCCATCATCTTCTTTCAGATCCAGCTTTACGCCAGCCTGCTGCTGCAGCTGTTCTTTTTTGCCGCT
AACGTTTACGGCTGGTATGCATGGTCGCGACAAAGCAGCAACCATGAGGCTGAGCTGCAGATCCGCTGGCTGCCGCGCAG
CAAAGCGCTGGGCTGGCTGGCGGCCTGCGTGGTAGCGATCGGCTTGCTGACCCTGTTTATCAACCCGTTCTTTGCTTTCC
TGACGCGGATTGCGGTCAGCCTGATGCAAGCGCTCGGTTTGCAGGTCACTATGCCGGAACTGCAGCCGGATGCTTTCCCG
TTCTGGGACTCCTGTATGACGGTGCTGTCGGTGGTGGCGATGATCTTAATGACCCGCAAGTATGTTGAAAACTGGCTGCT
GTGGGTGATCGTCAACGTGATAAGCGTGGTGATTTTTGCCCGTCAGGGCGTCTATGCCATGTCGCTGGAATACCTCTTGC
TGACGTTCATTGCGTTGAACGGCAGCCGGATGTGGATAAATAGCGCGCGTGAGCGAGGTTCTCACGCGTTTTCTGGCTAA

Upstream 100 bases:

>100_bases
TGCGAACCGGCGCATTAATTCCCCTTAACCGGATGCTGGATTTTGCGGCTACACTACGGGGATAACCTATTGTCGCGTCG
CCAGACGCTGAGGGGAGGAA

Downstream 100 bases:

>100_bases
TGGTGGTGGTGATGATCGTGCCCGGCGTGCATCGTGTTGAGATGGCACTCCGGGCCGCTGCAGGGCTGGTACTCCATCTG
CACCGTGGCATGCGCAATTT

Product: nucleoside/purine/pyrimidine transport protein

Products: nicotinamide nucleotide [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MDFFSTQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEKISNYAFGLVNVTLFAIIFFQIQLYASLLLQLFFFAA
NVYGWYAWSRQSSNHEAELQIRWLPRSKALGWLAACVVAIGLLTLFINPFFAFLTRIAVSLMQALGLQVTMPELQPDAFP
FWDSCMTVLSVVAMILMTRKYVENWLLWVIVNVISVVIFARQGVYAMSLEYLLLTFIALNGSRMWINSARERGSHAFSG

Sequences:

>Translated_239_residues
MDFFSTQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEKISNYAFGLVNVTLFAIIFFQIQLYASLLLQLFFFAA
NVYGWYAWSRQSSNHEAELQIRWLPRSKALGWLAACVVAIGLLTLFINPFFAFLTRIAVSLMQALGLQVTMPELQPDAFP
FWDSCMTVLSVVAMILMTRKYVENWLLWVIVNVISVVIFARQGVYAMSLEYLLLTFIALNGSRMWINSARERGSHAFSG
>Mature_239_residues
MDFFSTQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEKISNYAFGLVNVTLFAIIFFQIQLYASLLLQLFFFAA
NVYGWYAWSRQSSNHEAELQIRWLPRSKALGWLAACVVAIGLLTLFINPFFAFLTRIAVSLMQALGLQVTMPELQPDAFP
FWDSCMTVLSVVAMILMTRKYVENWLLWVIVNVISVVIFARQGVYAMSLEYLLLTFIALNGSRMWINSARERGSHAFSG

Specific function: Required for nicotinamide riboside transport across the inner membrane [H]

COG id: COG3201

COG function: function code H; Nicotinamide mononucleotide transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786965, Length=238, Percent_Identity=86.9747899159664, Blast_Score=405, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006419 [H]

Pfam domain/function: PF04973 NMN_transporter [H]

EC number: NA

Molecular weight: Translated: 26941; Mature: 26941

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFFSTQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEKISNYAFGLVNVTLFAI
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFQIQLYASLLLQLFFFAANVYGWYAWSRQSSNHEAELQIRWLPRSKALGWLAACVVAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
GLLTLFINPFFAFLTRIAVSLMQALGLQVTMPELQPDAFPFWDSCMTVLSVVAMILMTRK
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YVENWLLWVIVNVISVVIFARQGVYAMSLEYLLLTFIALNGSRMWINSARERGSHAFSG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDFFSTQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIWLASLEKISNYAFGLVNVTLFAI
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IFFQIQLYASLLLQLFFFAANVYGWYAWSRQSSNHEAELQIRWLPRSKALGWLAACVVAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHH
GLLTLFINPFFAFLTRIAVSLMQALGLQVTMPELQPDAFPFWDSCMTVLSVVAMILMTRK
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
YVENWLLWVIVNVISVVIFARQGVYAMSLEYLLLTFIALNGSRMWINSARERGSHAFSG
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: nicotinamide nucleotide [Periplasm] [C]

Specific reaction: nicotinamide nucleotide [Periplasm] = nicotinamide nucleotide [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 2841129; 2198247 [H]