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The map label for this gene is nadA [H]

Identifier: 238893779

GI number: 238893779

Start: 1648607

End: 1649650

Strand: Direct

Name: nadA [H]

Synonym: KP1_1706

Alternate gene names: 238893779

Gene position: 1648607-1649650 (Clockwise)

Preceding gene: 238893778

Following gene: 238893780

Centisome position: 31.41

GC content: 60.44

Gene sequence:

>1044_bases
ATGAGCGTAATGTTTGATCCTGAAACGGCGATTTATCCTTTCCCTGCTAAACCGCAGCCGCTGACCGTCGACGAAAAGCA
GTTTTACCGCGAAAAAATCAAGCGCCTGCTGCGCGAGCGCGATGCCGTGATGGTGGCGCATTACTACACCGATCCTGAAA
TTCAACAGCTGGCGGAAGAGACCGGCGGCTGTATCGCCGACTCGCTGGAGATGGCGCGCTTTGGCGCCCGCCATTCGGCC
TCCACGCTGCTGGTCGCCGGGGTGCGTTTTATGGGGGAAACCGCCAAAATCCTCAGCCCGGAAAAGACCATTTTGATGCC
GACCCTGAACGCCGAGTGTTCATTGGATCTGGGCTGTCCGATTGAGGAATTCAACGCCTTTTGCGACGCCCATCCTGACC
GCACCGTCGTGGTCTATGCCAATACGTCCGCCGCGGTGAAGGCCCGCGCCGACTGGGTGGTGACCTCCAGCATCGCCGTG
GAACTCATTGACCATCTGGATAGTCTTGGTCAAAAGATCCTCTGGGCGCCGGACCGCCACCTTGGGCGCTACGTTCAGCG
TCAGACCGGCGCAGACGTGCTGTGCTGGCAGGGGGCGTGCATCGTGCACGACGAGTTTAAAACCCAGGCGTTGATGCGGA
TGAAGGCTCTGCATCCCGAAGCCGCCGTGCTGGTCCATCCCGAGTCGCCGCAGGCGATCGTTGAGATGGCCGATGCCGTA
GGCTCCACCAGCCAGCTGATTGCGGCGGCGAAAAGCCTGCCCCAGCGCCAGCTGATCGTGGCCACCGATCGCGGTATTTT
CTATAAAATGCAGCAGGCGGTGCCGGAGAAAACGCTGCTGGAAGCGCCCACCGCCGGCGAAGGGGCGACCTGCCGCAGCT
GCGCGCATTGTCCGTGGATGGCGATGAATGGCCTGAAAGCCATTGCCGAGGGTCTCGAGCAGGGCGGCGCTGAACATGAA
ATCCATGTCGACGAAGCGCTGCGAACCGGCGCATTAATTCCCCTTAACCGGATGCTGGATTTTGCGGCTACACTACGGGG
ATAA

Upstream 100 bases:

>100_bases
CGGCTATCTTGTTTAGCATATAAAACACCATGACCGTGTTAAGCCGCTGACAGGCCATACTGACGGTTGTAGAGTTAAGC
CAGTAAAACGAGATTGCATG

Downstream 100 bases:

>100_bases
CCTATTGTCGCGTCGCCAGACGCTGAGGGGAGGAAATGGATTTTTTTAGCACGCAGAATATTTTAGTACATATACCCATC
GGCGCTGGGGGGTACGATCT

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSVMFDPETAIYPFPAKPQPLTVDEKQFYREKIKRLLRERDAVMVAHYYTDPEIQQLAEETGGCIADSLEMARFGARHSA
STLLVAGVRFMGETAKILSPEKTILMPTLNAECSLDLGCPIEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
ELIDHLDSLGQKILWAPDRHLGRYVQRQTGADVLCWQGACIVHDEFKTQALMRMKALHPEAAVLVHPESPQAIVEMADAV
GSTSQLIAAAKSLPQRQLIVATDRGIFYKMQQAVPEKTLLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAEHE
IHVDEALRTGALIPLNRMLDFAATLRG

Sequences:

>Translated_347_residues
MSVMFDPETAIYPFPAKPQPLTVDEKQFYREKIKRLLRERDAVMVAHYYTDPEIQQLAEETGGCIADSLEMARFGARHSA
STLLVAGVRFMGETAKILSPEKTILMPTLNAECSLDLGCPIEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
ELIDHLDSLGQKILWAPDRHLGRYVQRQTGADVLCWQGACIVHDEFKTQALMRMKALHPEAAVLVHPESPQAIVEMADAV
GSTSQLIAAAKSLPQRQLIVATDRGIFYKMQQAVPEKTLLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAEHE
IHVDEALRTGALIPLNRMLDFAATLRG
>Mature_346_residues
SVMFDPETAIYPFPAKPQPLTVDEKQFYREKIKRLLRERDAVMVAHYYTDPEIQQLAEETGGCIADSLEMARFGARHSAS
TLLVAGVRFMGETAKILSPEKTILMPTLNAECSLDLGCPIEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVE
LIDHLDSLGQKILWAPDRHLGRYVQRQTGADVLCWQGACIVHDEFKTQALMRMKALHPEAAVLVHPESPQAIVEMADAVG
STSQLIAAAKSLPQRQLIVATDRGIFYKMQQAVPEKTLLEAPTAGEGATCRSCAHCPWMAMNGLKAIAEGLEQGGAEHEI
HVDEALRTGALIPLNRMLDFAATLRG

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=347, Percent_Identity=87.0317002881844, Blast_Score=646, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38037; Mature: 37906

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVMFDPETAIYPFPAKPQPLTVDEKQFYREKIKRLLRERDAVMVAHYYTDPEIQQLAEE
CCEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
TGGCIADSLEMARFGARHSASTLLVAGVRFMGETAKILSPEKTILMPTLNAECSLDLGCP
HCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCEECCCC
IEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGQKILWAPDRH
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCHHEECCCCHH
LGRYVQRQTGADVLCWQGACIVHDEFKTQALMRMKALHPEAAVLVHPESPQAIVEMADAV
HHHHHHHHCCCCEEEECCEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIAAAKSLPQRQLIVATDRGIFYKMQQAVPEKTLLEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCCCHHHCCCCHH
AMNGLKAIAEGLEQGGAEHEIHVDEALRTGALIPLNRMLDFAATLRG
HHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SVMFDPETAIYPFPAKPQPLTVDEKQFYREKIKRLLRERDAVMVAHYYTDPEIQQLAEE
CEEECCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHH
TGGCIADSLEMARFGARHSASTLLVAGVRFMGETAKILSPEKTILMPTLNAECSLDLGCP
HCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHCCCCCEEEEEECCCCCCEECCCC
IEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAVELIDHLDSLGQKILWAPDRH
HHHHHHHHCCCCCCEEEEEECCCCEEEECCCEEEHHHHHHHHHHHHHHHCHHEECCCCHH
LGRYVQRQTGADVLCWQGACIVHDEFKTQALMRMKALHPEAAVLVHPESPQAIVEMADAV
HHHHHHHHCCCCEEEECCEEEEEHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHH
GSTSQLIAAAKSLPQRQLIVATDRGIFYKMQQAVPEKTLLEAPTAGEGATCRSCAHCPWM
CCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHCCHHHHHCCCCCCCCCCCHHHCCCCHH
AMNGLKAIAEGLEQGGAEHEIHVDEALRTGALIPLNRMLDFAATLRG
HHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA