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The map label for this gene is dcuC [H]

Identifier: 238893689

GI number: 238893689

Start: 1552039

End: 1553412

Strand: Reverse

Name: dcuC [H]

Synonym: KP1_1608

Alternate gene names: 238893689

Gene position: 1553412-1552039 (Counterclockwise)

Preceding gene: 238893692

Following gene: 238893688

Centisome position: 29.6

GC content: 56.99

Gene sequence:

>1374_bases
ATGCTGACGTTTATTGAGATCCTGATAGGGATCGTGGTCATTGTGGGCGTAGCCCGCTATATCATTAAAGGCTACTCGGC
CACCGGGGTCCTGTTCGTCGGAGGCTTAATCTTACTGATCGTCAGCGCCCTGCTGGGACATAAAGTGTTACCGGGTAATA
CCGCGAGCACCGGCTATTCCGCTACCGATATTATTGAATACATTAAGATTCTACTCATGAGCCGCGGCGGCGATTTGGGT
ATGATGATCATGATGCTATGCGGCTTCGCCACCTATATGACCCATATTGGCGCTAATGATATGGTGGTCAAATTAGCGTC
GAAGCCGTTGCGCTATATTAATTCGCCCTATCTGCTGATGATTGCCGCCTATTTTGTCGCCTGCCTGATGTCGCTGGCCG
TCTCCTCCGCGACCGGCCTTGGCGTACTGCTGATGGCGACGCTGTTCCCGGTAATGGTGAATGTCGGTATCAGCCGCGGG
GCCGCCGCCGCCATCTGCGCCTCACCGGCGGCGATTATCCTCTCGCCAACCTCGGGTGACGTCGTCCTGGCGGCCAAAGC
CGCTGAAATGCCGCTGATCGACTTTGCTTTTAAAACCACGCTGCCGATCTCCATCGCGGCTATTATCTGCATGGCGATCG
CCCACTTTTTCTGGCAGCGCTATCTGGATAAAAAAGAGCACATTTCTCACGAGATGCTCGATGTCAACGACATCACCACC
ACCGCCCCGGCGCTGTATGCCATTCTGCCGTTTACCCCGATCATCGGCGTGCTGATCTTTGACGGTAAATGGGGGCCGGA
GCTGCACATTATCACCATCCTCGTTGGCTGCATGCTGCTGGCGGCGATCCTCGAGTTCCTGCGCGGTTTCAACACCAAAA
ACGTCTTTAGCGGGCTGGAAGTCGCCTACCGTGGAATGGCCGACGCCTTCGCCGGCGTAGTGATGCTGTTGGTTGCCGCC
GGCGTCTTTGCCCAGGGGTTAAGCACTATCGGCTTTATCAACGGTCTGATCTCAATCGCCACCTCCTTCGGCTCGGCCAG
TATTATTCTGATGCTGGTGCTGGTGATCCTGACCATGCTGGCGGCGATGACCACCGGTTCCGGTAATGCCCCGTTCTACG
CCTTCGTTGAGATGATCCCCAAGCTGGCGCACTCCTCCGGCATCAATCCGGCCTACCTGTCGATTCCGATGCTGCAGGCT
TCTAACCTCGGCCGCACGATATCGCCCGTCTCCGGGGTGGTGGTCGCCGTTGCCGGGATGGCGAAGATTTCCCCATTCGA
AGTGGTCAAGCGCACCTCAGTGCCGGTGCTCGTTGGCCTGCTGGTGGTGATCGTTGCTACTGAAATCCTGGTGCCCGGCA
GCGCGCTCCACTAA

Upstream 100 bases:

>100_bases
TTTGCATCAGCGAGTTTTGTCCGTTTTTTCGGCACATTCGCACATTAAAATTTGGTGTGGTGCTTTTTAGCTACATATTC
TTTGGGTTTAGGGGTAATAA

Downstream 100 bases:

>100_bases
TGGTCTAACCACGCGAAAAGGCGCCAGCGGGCGCCTTTTTTATGCTTTAATAACTCCCCGTTATCTTTTGCCATCCATAA
TCAGGAATAAAAATGTTCAG

Product: C4-dicarboxylate transporter DcuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MLTFIEILIGIVVIVGVARYIIKGYSATGVLFVGGLILLIVSALLGHKVLPGNTASTGYSATDIIEYIKILLMSRGGDLG
MMIMMLCGFATYMTHIGANDMVVKLASKPLRYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
AAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIICMAIAHFFWQRYLDKKEHISHEMLDVNDITT
TAPALYAILPFTPIIGVLIFDGKWGPELHIITILVGCMLLAAILEFLRGFNTKNVFSGLEVAYRGMADAFAGVVMLLVAA
GVFAQGLSTIGFINGLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQA
SNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLLVVIVATEILVPGSALH

Sequences:

>Translated_457_residues
MLTFIEILIGIVVIVGVARYIIKGYSATGVLFVGGLILLIVSALLGHKVLPGNTASTGYSATDIIEYIKILLMSRGGDLG
MMIMMLCGFATYMTHIGANDMVVKLASKPLRYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
AAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIICMAIAHFFWQRYLDKKEHISHEMLDVNDITT
TAPALYAILPFTPIIGVLIFDGKWGPELHIITILVGCMLLAAILEFLRGFNTKNVFSGLEVAYRGMADAFAGVVMLLVAA
GVFAQGLSTIGFINGLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQA
SNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLLVVIVATEILVPGSALH
>Mature_457_residues
MLTFIEILIGIVVIVGVARYIIKGYSATGVLFVGGLILLIVSALLGHKVLPGNTASTGYSATDIIEYIKILLMSRGGDLG
MMIMMLCGFATYMTHIGANDMVVKLASKPLRYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
AAAAICASPAAIILSPTSGDVVLAAKAAEMPLIDFAFKTTLPISIAAIICMAIAHFFWQRYLDKKEHISHEMLDVNDITT
TAPALYAILPFTPIIGVLIFDGKWGPELHIITILVGCMLLAAILEFLRGFNTKNVFSGLEVAYRGMADAFAGVVMLLVAA
GVFAQGLSTIGFINGLISIATSFGSASIILMLVLVILTMLAAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQA
SNLGRTISPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLLVVIVATEILVPGSALH

Specific function: Responsible for the transport of C4-dicarboxylates during anaerobic growth [H]

COG id: COG3069

COG function: function code C; C4-dicarboxylate transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dcuC/dcuD transporter (TC 2.A.61) family [H]

Homologues:

Organism=Escherichia coli, GI1786839, Length=455, Percent_Identity=91.4285714285714, Blast_Score=702, Evalue=0.0,
Organism=Escherichia coli, GI1789622, Length=447, Percent_Identity=36.4653243847875, Blast_Score=279, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018385
- InterPro:   IPR004669 [H]

Pfam domain/function: PF03606 DcuC [H]

EC number: NA

Molecular weight: Translated: 47979; Mature: 47979

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTFIEILIGIVVIVGVARYIIKGYSATGVLFVGGLILLIVSALLGHKVLPGNTASTGYS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ATDIIEYIKILLMSRGGDLGMMIMMLCGFATYMTHIGANDMVVKLASKPLRYINSPYLLM
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHH
IAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAICASPAAIILSPTSGD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCC
VVLAAKAAEMPLIDFAFKTTLPISIAAIICMAIAHFFWQRYLDKKEHISHEMLDVNDITT
EEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCH
TAPALYAILPFTPIIGVLIFDGKWGPELHIITILVGCMLLAAILEFLRGFNTKNVFSGLE
HHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VAYRGMADAFAGVVMLLVAAGVFAQGLSTIGFINGLISIATSFGSASIILMLVLVILTML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQASNLGRTISPVSGVVVAVAGM
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEHHHHCCCCCCCCHHHHHHHHHHHH
AKISPFEVVKRTSVPVLVGLLVVIVATEILVPGSALH
HHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLTFIEILIGIVVIVGVARYIIKGYSATGVLFVGGLILLIVSALLGHKVLPGNTASTGYS
CHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
ATDIIEYIKILLMSRGGDLGMMIMMLCGFATYMTHIGANDMVVKLASKPLRYINSPYLLM
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHH
IAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRGAAAAICASPAAIILSPTSGD
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCCCEEEEECCCCC
VVLAAKAAEMPLIDFAFKTTLPISIAAIICMAIAHFFWQRYLDKKEHISHEMLDVNDITT
EEEEECCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCCH
TAPALYAILPFTPIIGVLIFDGKWGPELHIITILVGCMLLAAILEFLRGFNTKNVFSGLE
HHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VAYRGMADAFAGVVMLLVAAGVFAQGLSTIGFINGLISIATSFGSASIILMLVLVILTML
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
AAMTTGSGNAPFYAFVEMIPKLAHSSGINPAYLSIPMLQASNLGRTISPVSGVVVAVAGM
HHHCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEHHHHCCCCCCCCHHHHHHHHHHHH
AKISPFEVVKRTSVPVLVGLLVVIVATEILVPGSALH
HHCCHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]