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The map label for this gene is dsbG [H]

Identifier: 238893682

GI number: 238893682

Start: 1546391

End: 1547140

Strand: Reverse

Name: dsbG [H]

Synonym: KP1_1600

Alternate gene names: 238893682

Gene position: 1547140-1546391 (Counterclockwise)

Preceding gene: 238893683

Following gene: 238893681

Centisome position: 29.48

GC content: 53.6

Gene sequence:

>750_bases
ATGTTAAAGCGTCTGCTGTTACTCAGCCTTTTGCCGTTATGCAGCCATGCGGAGGAACTCCCCGCTCCGGTAAAAGCGAT
TGAAAAACAGGGCATTACCATTATAAAACCCTTTGAGGCGCCGGGGGGAATGAAAGGCTGGCTGGGCAAATACCAGGACA
TGGGGGTCGCCATCTACCTAACGCCGGATGGTAAACACGCGATCTCCGGCTATATGTATGATGAGAACGGCAGCAACCTC
AGCGAGCAGCTGTTTCAGAAAGAACTCTATACCCCGGCGGGACAAGAGATGTGGAAGAAGATGGCCAGCGCCCACTGGCT
GCAGGATGGTCGCAAGGACGCCCCTATCGTGCTGTATGTCTTTGCCGATCCCTTCTGTCCCTACTGCAAGCAGTTCTGGC
AGCAATCCCGCCCCTGGGTAGAGGCCGGTAAAGTGCAGATCCGCACTCTGCTGGTGGGGGTGATCAAGCCGGAGAGCCCG
GCCACCGCCGCGGCGATTCTCGCCAGCAACGATCCGGCGAAAACCTGGCATGATTACGAGCAATCGAATGGGAAAATGGC
TCTGACGATCCCGAAAGTTATTCCGCCGGAGAAAATGAAAATGCTCAACGTCAACCAGCAGCTGATGGACGATCTGGGAG
CCAACGTGACGCCGGCGATTTATTATATGAATAAAGATAATATGCTGCAGCAGGTGGTCGGCCTACCGGATAAAGAGAAA
CTGCATATTATGATGGGTGAAAAAGAGTAA

Upstream 100 bases:

>100_bases
GCCAGCAAAGGGCAATCCGTCATTCTGCTGATCTTGCCTATGACTGTGATAGGTTCGACAATCGTTTTGCCCTTTCCTGC
TGATTTTACAAGGAATACTT

Downstream 100 bases:

>100_bases
TTCCATCCCGCAATGGCGCCTGGCGGAAGCGACCGCTGGCGCCACCGTCGACGATAAGATATATTAAGCAGAACTTAACT
GTATTTGCCAATAGTTAAAT

Product: periplasmic disulfide isomerase/thiol-disulphide oxidase

Products: protein with oxidized disulfide bonds [C]

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLKRLLLLSLLPLCSHAEELPAPVKAIEKQGITIIKPFEAPGGMKGWLGKYQDMGVAIYLTPDGKHAISGYMYDENGSNL
SEQLFQKELYTPAGQEMWKKMASAHWLQDGRKDAPIVLYVFADPFCPYCKQFWQQSRPWVEAGKVQIRTLLVGVIKPESP
ATAAAILASNDPAKTWHDYEQSNGKMALTIPKVIPPEKMKMLNVNQQLMDDLGANVTPAIYYMNKDNMLQQVVGLPDKEK
LHIMMGEKE

Sequences:

>Translated_249_residues
MLKRLLLLSLLPLCSHAEELPAPVKAIEKQGITIIKPFEAPGGMKGWLGKYQDMGVAIYLTPDGKHAISGYMYDENGSNL
SEQLFQKELYTPAGQEMWKKMASAHWLQDGRKDAPIVLYVFADPFCPYCKQFWQQSRPWVEAGKVQIRTLLVGVIKPESP
ATAAAILASNDPAKTWHDYEQSNGKMALTIPKVIPPEKMKMLNVNQQLMDDLGANVTPAIYYMNKDNMLQQVVGLPDKEK
LHIMMGEKE
>Mature_249_residues
MLKRLLLLSLLPLCSHAEELPAPVKAIEKQGITIIKPFEAPGGMKGWLGKYQDMGVAIYLTPDGKHAISGYMYDENGSNL
SEQLFQKELYTPAGQEMWKKMASAHWLQDGRKDAPIVLYVFADPFCPYCKQFWQQSRPWVEAGKVQIRTLLVGVIKPESP
ATAAAILASNDPAKTWHDYEQSNGKMALTIPKVIPPEKMKMLNVNQQLMDDLGANVTPAIYYMNKDNMLQQVVGLPDKEK
LHIMMGEKE

Specific function: Involved in disulfide bond formation. Functions probably as a disulfide isomerase with a narrower substrate specificity than DsbC. DsbG is maintained in a reduced state by DsbD. In vitro, displays chaperone activity in both redox states [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081762, Length=232, Percent_Identity=75, Blast_Score=380, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 27977; Mature: 27977

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRLLLLSLLPLCSHAEELPAPVKAIEKQGITIIKPFEAPGGMKGWLGKYQDMGVAIYL
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCEEEEE
TPDGKHAISGYMYDENGSNLSEQLFQKELYTPAGQEMWKKMASAHWLQDGRKDAPIVLYV
CCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
FADPFCPYCKQFWQQSRPWVEAGKVQIRTLLVGVIKPESPATAAAILASNDPAKTWHDYE
ECCCCCHHHHHHHHCCCCCHHHHHEEEEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHH
QSNGKMALTIPKVIPPEKMKMLNVNQQLMDDLGANVTPAIYYMNKDNMLQQVVGLPDKEK
HCCCEEEEEECCCCCHHHHHHHCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCE
LHIMMGEKE
EEEEECCCC
>Mature Secondary Structure
MLKRLLLLSLLPLCSHAEELPAPVKAIEKQGITIIKPFEAPGGMKGWLGKYQDMGVAIYL
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEECCCCCCCCHHHHHHHHHCCEEEEE
TPDGKHAISGYMYDENGSNLSEQLFQKELYTPAGQEMWKKMASAHWLQDGRKDAPIVLYV
CCCCCCEEEEEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEE
FADPFCPYCKQFWQQSRPWVEAGKVQIRTLLVGVIKPESPATAAAILASNDPAKTWHDYE
ECCCCCHHHHHHHHCCCCCHHHHHEEEEEEEEEEECCCCCCCEEEEEECCCCCHHHHHHH
QSNGKMALTIPKVIPPEKMKMLNVNQQLMDDLGANVTPAIYYMNKDNMLQQVVGLPDKEK
HCCCEEEEEECCCCCHHHHHHHCCCHHHHHHHCCCCCEEEEEECCHHHHHHHHCCCCCCE
LHIMMGEKE
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein with reduced SH groups [C]

Specific reaction: protein with reduced SH groups = protein with oxidized disulfide bonds [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]