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The map label for this gene is mtnC [H]

Identifier: 238893677

GI number: 238893677

Start: 1541356

End: 1542114

Strand: Reverse

Name: mtnC [H]

Synonym: KP1_1595

Alternate gene names: 238893677

Gene position: 1542114-1541356 (Counterclockwise)

Preceding gene: 238893679

Following gene: 238893676

Centisome position: 29.38

GC content: 56.92

Gene sequence:

>759_bases
TTGGCAATCAAGACGCTTAGACGTCTAAATGCTAATGTTATTCCACGCTACGCCCACTCTGGAGAAACCATGATCCGCGC
CATCGTGACCGACATAGAAGGCACCACCAGCGATATCCGCTTCGTGCATAACGTGCTGTTCCCCTACGCCCGCGAACGAC
TGGCCGGCTTTGTGACCGCTCAGCAGCACGCTGAACCGGTCAAAACCATTCTCGACAACCTGCGCCGCGAAACAGACGCC
CCCGCCGCCAGCACCGCCGACCTTATCACTACCCTCTTCGCCTTTATGGATGAAGACCGTAAATCCACGGCGCTGAAGGC
GCTGCAGGGGATCATCTGGCGTGACGGCTATCTCAACGGCGACTTTACCGGCCATCTCTACCCGGACGTACTGCCGGCGC
TGGAGAAATGGAAAGCGCAGGGTATTGATCTGTATGTATATTCCTCAGGTTCCGTGGCTGCGCAGAAATTGTTATTTGGC
TACAGCGATGAAGGTGATATTACTCATCTGTTCACGGGCTATTTCGATACCCTGGTAGGCGCCAAACGTGAGGTGCAGTC
CTACCGTAACATTGCTGAACACCTGGGCCATGCCCCTGGCACCATCCTGTTCCTGTCGGATATCCATCAGGAGCTCGACG
CCGCCGAGGCCGCGGGTTTGCGAACGATCCAGTTGGTACGCGGCGACCGCGACCCGGCGAGCCACCATCCTCAGGTTCAG
CGTTTTGACGACATTCATCCGGAGCAGATCCCAGCATGA

Upstream 100 bases:

>100_bases
GCGCAGGAAGTTTACTCTCTGGAATCAAGGGGTTATTGTTCATTCTTTTTATACCGATTGTAATGCTGTTGTTGAAGCCA
CTATAACACGATGTTAATAT

Downstream 100 bases:

>100_bases
GCGCATTAACTCTTTTTTCCGTGACCGATCCGCAAACGCCGGTCTGGCACAGCACCGACGCCAAAGCGATTCAGGATCAA
CTTAACGCCAAAGGCGTCCG

Product: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase

Products: NA

Alternate protein names: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase [H]

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MAIKTLRRLNANVIPRYAHSGETMIRAIVTDIEGTTSDIRFVHNVLFPYARERLAGFVTAQQHAEPVKTILDNLRRETDA
PAASTADLITTLFAFMDEDRKSTALKALQGIIWRDGYLNGDFTGHLYPDVLPALEKWKAQGIDLYVYSSGSVAAQKLLFG
YSDEGDITHLFTGYFDTLVGAKREVQSYRNIAEHLGHAPGTILFLSDIHQELDAAEAAGLRTIQLVRGDRDPASHHPQVQ
RFDDIHPEQIPA

Sequences:

>Translated_252_residues
MAIKTLRRLNANVIPRYAHSGETMIRAIVTDIEGTTSDIRFVHNVLFPYARERLAGFVTAQQHAEPVKTILDNLRRETDA
PAASTADLITTLFAFMDEDRKSTALKALQGIIWRDGYLNGDFTGHLYPDVLPALEKWKAQGIDLYVYSSGSVAAQKLLFG
YSDEGDITHLFTGYFDTLVGAKREVQSYRNIAEHLGHAPGTILFLSDIHQELDAAEAAGLRTIQLVRGDRDPASHHPQVQ
RFDDIHPEQIPA
>Mature_251_residues
AIKTLRRLNANVIPRYAHSGETMIRAIVTDIEGTTSDIRFVHNVLFPYARERLAGFVTAQQHAEPVKTILDNLRRETDAP
AASTADLITTLFAFMDEDRKSTALKALQGIIWRDGYLNGDFTGHLYPDVLPALEKWKAQGIDLYVYSSGSVAAQKLLFGY
SDEGDITHLFTGYFDTLVGAKREVQSYRNIAEHLGHAPGTILFLSDIHQELDAAEAAGLRTIQLVRGDRDPASHHPQVQR
FDDIHPEQIPA

Specific function: Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone

COG id: COG4229

COG function: function code C; Predicted enolase-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. MasA/mtnC family [H]

Homologues:

Organism=Homo sapiens, GI10864017, Length=223, Percent_Identity=42.152466367713, Blast_Score=165, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI115533232, Length=215, Percent_Identity=41.3953488372093, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6320797, Length=201, Percent_Identity=36.318407960199, Blast_Score=113, Evalue=3e-26,
Organism=Drosophila melanogaster, GI281360080, Length=219, Percent_Identity=44.2922374429224, Blast_Score=184, Evalue=4e-47,
Organism=Drosophila melanogaster, GI24644163, Length=219, Percent_Identity=44.2922374429224, Blast_Score=184, Evalue=4e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR010041
- InterPro:   IPR023214
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.77 [H]

Molecular weight: Translated: 28096; Mature: 27965

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIKTLRRLNANVIPRYAHSGETMIRAIVTDIEGTTSDIRFVHNVLFPYARERLAGFVTA
CCHHHHHHHCCCCCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QQHAEPVKTILDNLRRETDAPAASTADLITTLFAFMDEDRKSTALKALQGIIWRDGYLNG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
DFTGHLYPDVLPALEKWKAQGIDLYVYSSGSVAAQKLLFGYSDEGDITHLFTGYFDTLVG
CCCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AKREVQSYRNIAEHLGHAPGTILFLSDIHQELDAAEAAGLRTIQLVRGDRDPASHHPQVQ
HHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHH
RFDDIHPEQIPA
HHCCCCCCCCCC
>Mature Secondary Structure 
AIKTLRRLNANVIPRYAHSGETMIRAIVTDIEGTTSDIRFVHNVLFPYARERLAGFVTA
CHHHHHHHCCCCCCCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
QQHAEPVKTILDNLRRETDAPAASTADLITTLFAFMDEDRKSTALKALQGIIWRDGYLNG
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCC
DFTGHLYPDVLPALEKWKAQGIDLYVYSSGSVAAQKLLFGYSDEGDITHLFTGYFDTLVG
CCCCCCCHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AKREVQSYRNIAEHLGHAPGTILFLSDIHQELDAAEAAGLRTIQLVRGDRDPASHHPQVQ
HHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHH
RFDDIHPEQIPA
HHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA