| Definition | Klebsiella pneumoniae NTUH-K2044 chromosome, complete genome. |
|---|---|
| Accession | NC_012731 |
| Length | 5,248,520 |
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The map label for this gene is scrB [H]
Identifier: 238893527
GI number: 238893527
Start: 1374496
End: 1375896
Strand: Reverse
Name: scrB [H]
Synonym: KP1_1429
Alternate gene names: 238893527
Gene position: 1375896-1374496 (Counterclockwise)
Preceding gene: 238893528
Following gene: 238893526
Centisome position: 26.21
GC content: 65.52
Gene sequence:
>1401_bases ATGTCATTACCGTCACGCCTGCCTGCGATCCTGCAGGCCGTTATGCAGGGCCAGCCGCAGGCGCTGGCCGACAGCCATTA TCCGCAATGGCATCTGGCGCCGGTCAACGGACTGCTGAACGATCCTAACGGCTTTTGCCAGGTCGCCGGGCGTTACCACC TGTTTTATCAGTGGAACCCGCTCGCCTGCGACCATACCTATAAGTGCTGGGGACACTGGAGCTCTGCCGATCTGCTGCAC TGGCGGCACGAACCTATCGCCCTGATGCCGGATGAAGAGTATGACCGCAACGGCTGCTACTCTGGCAGCGCGGTCGAGTT CGAGGGCGCCCTGACTCTGTGCTACACCGGCAACGTGAAATTCCCCGACGGCGGGCGCACCGCCTGGCAATGTCTGGCGA CCGAGAATGCCGATGGCACCTTCCGCAAGCTGGGGCCGGTGCTGCCGCTGCCAGAAGGCTATACCGGCCATGTGCGCGAC CCTAAAGTGTGGCGGCAGGACGGGCGCTGGTACATGGTTCTTGGGGCGCAGGATGTGCAACAGCGCGGCAAAGTGCTGCT GTTTACCGCCAGCGACCTGCGGGAGTGGCGCCTGGTAGGGGAGATCGCCGGGCACGACGTGAACGGCCTGGCGAACGCCG GCTACATGTGGGAGTGCCCGGATCTCTTTCCGCTGGCGGACACCCACCTGCTGATCTGCTGCCCGCAGGGGCTGGCCCGC GAAGCGCAGCGCTTTCTCAATACCTATCCGGCGGTATGGATGGCAGGCCGCTTCGACGCCGAACGCGGGATCTTCGACCA CGGCCCGCTGCACGAGCTGGACAGCGGATTTGAGTTCTACGCGCCGCAGACCATGCAGGCAAAAGATGGCCGCCGCCTGC TGGTCGGCTGGATGGGCGTCCCCGACGGGGAAGAGATGCATCAGCCCACCCGCGCGCAGGGCTGGATCCATCAGATGACC TGCGTGCGTGAGCTGGAGTGGCAGGCTGGCACTCTGTATCAGCGTCCGCTGCGCGAGCTGGCCGCTCTGCGCGGGGAAGC CCAGGGCTGGCGCGGGCAGACCCTGCCCCTCGCCCCGATGGAGCTGGCCTTTGACCTTTCCCCCGACAGCACGCTGGGGC TGGACTTTGCCGGCGCCCTGCAGCTCACCGTCAATCGCGACGGCCTACGTCTGTCGCGCCGCGGCCTGCAGACGGCAGAG ATGCATCACCGCTACTGGCGCGGCGAGGCGCGACGCCTGCGGATCTTTATCGACCGCTCCAGCGTGGAGATTTTCATCAA CGATGGCGAGGGGGTGATGAGCAGCCGCTTCTTCCCGGGCTATCCGGGGCAGCTCATCTTCAGCGGTGCGACGCCGGTGG CATTCTGCCGCTGGCTGCTGCGGCCATGCATGGTAGAATAA
Upstream 100 bases:
>100_bases AGGCCAGCTCGCTGCTGAACTACATTATCGGAATGGCGATCGCCTTCGCCGTGGCCTTCGCGCTCTCTCTGACGCTGAAA TACAAAACGGACGCTGAATA
Downstream 100 bases:
>100_bases GCGTTTTGCTTTCAGGCTCCCGGGTGCTGATGAAAACCAAACGCGTAACTATCAAAGATATCGCCGAACTGGCGGGCGTC TCCAAAGCGACCGCCAGCCT
Product: sucrose-6-phosphate hydrolase
Products: NA
Alternate protein names: Sucrase; Invertase [H]
Number of amino acids: Translated: 466; Mature: 465
Protein sequence:
>466_residues MSLPSRLPAILQAVMQGQPQALADSHYPQWHLAPVNGLLNDPNGFCQVAGRYHLFYQWNPLACDHTYKCWGHWSSADLLH WRHEPIALMPDEEYDRNGCYSGSAVEFEGALTLCYTGNVKFPDGGRTAWQCLATENADGTFRKLGPVLPLPEGYTGHVRD PKVWRQDGRWYMVLGAQDVQQRGKVLLFTASDLREWRLVGEIAGHDVNGLANAGYMWECPDLFPLADTHLLICCPQGLAR EAQRFLNTYPAVWMAGRFDAERGIFDHGPLHELDSGFEFYAPQTMQAKDGRRLLVGWMGVPDGEEMHQPTRAQGWIHQMT CVRELEWQAGTLYQRPLRELAALRGEAQGWRGQTLPLAPMELAFDLSPDSTLGLDFAGALQLTVNRDGLRLSRRGLQTAE MHHRYWRGEARRLRIFIDRSSVEIFINDGEGVMSSRFFPGYPGQLIFSGATPVAFCRWLLRPCMVE
Sequences:
>Translated_466_residues MSLPSRLPAILQAVMQGQPQALADSHYPQWHLAPVNGLLNDPNGFCQVAGRYHLFYQWNPLACDHTYKCWGHWSSADLLH WRHEPIALMPDEEYDRNGCYSGSAVEFEGALTLCYTGNVKFPDGGRTAWQCLATENADGTFRKLGPVLPLPEGYTGHVRD PKVWRQDGRWYMVLGAQDVQQRGKVLLFTASDLREWRLVGEIAGHDVNGLANAGYMWECPDLFPLADTHLLICCPQGLAR EAQRFLNTYPAVWMAGRFDAERGIFDHGPLHELDSGFEFYAPQTMQAKDGRRLLVGWMGVPDGEEMHQPTRAQGWIHQMT CVRELEWQAGTLYQRPLRELAALRGEAQGWRGQTLPLAPMELAFDLSPDSTLGLDFAGALQLTVNRDGLRLSRRGLQTAE MHHRYWRGEARRLRIFIDRSSVEIFINDGEGVMSSRFFPGYPGQLIFSGATPVAFCRWLLRPCMVE >Mature_465_residues SLPSRLPAILQAVMQGQPQALADSHYPQWHLAPVNGLLNDPNGFCQVAGRYHLFYQWNPLACDHTYKCWGHWSSADLLHW RHEPIALMPDEEYDRNGCYSGSAVEFEGALTLCYTGNVKFPDGGRTAWQCLATENADGTFRKLGPVLPLPEGYTGHVRDP KVWRQDGRWYMVLGAQDVQQRGKVLLFTASDLREWRLVGEIAGHDVNGLANAGYMWECPDLFPLADTHLLICCPQGLARE AQRFLNTYPAVWMAGRFDAERGIFDHGPLHELDSGFEFYAPQTMQAKDGRRLLVGWMGVPDGEEMHQPTRAQGWIHQMTC VRELEWQAGTLYQRPLRELAALRGEAQGWRGQTLPLAPMELAFDLSPDSTLGLDFAGALQLTVNRDGLRLSRRGLQTAEM HHRYWRGEARRLRIFIDRSSVEIFINDGEGVMSSRFFPGYPGQLIFSGATPVAFCRWLLRPCMVE
Specific function: Hydrolyzes sucrose and sucrose-6P, but fails to hydrolyze any of the phosphorylated isomers of sucrose and other phospho-D-glucosides, including maltose-6'P and trehalose-6P [H]
COG id: COG1621
COG function: function code G; Beta-fructosidases (levanase/invertase)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the glycosyl hydrolase 32 family [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR008985 - InterPro: IPR001362 - InterPro: IPR018053 - InterPro: IPR013189 - InterPro: IPR013148 - InterPro: IPR006232 [H]
Pfam domain/function: PF08244 Glyco_hydro_32C; PF00251 Glyco_hydro_32N [H]
EC number: =3.2.1.26 [H]
Molecular weight: Translated: 52761; Mature: 52629
Theoretical pI: Translated: 6.40; Mature: 6.40
Prosite motif: PS00609 GLYCOSYL_HYDROL_F32
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.6 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 5.6 %Cys+Met (Translated Protein) 2.6 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 5.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSLPSRLPAILQAVMQGQPQALADSHYPQWHLAPVNGLLNDPNGFCQVAGRYHLFYQWNP CCCCHHHHHHHHHHHCCCCCHHHCCCCCCEEEEECCCCCCCCCCCEEECCEEEEEEEECC LACDHTYKCWGHWSSADLLHWRHEPIALMPDEEYDRNGCYSGSAVEFEGALTLCYTGNVK CCCCCCEEEECCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCEEEECCEEEEEEECCEE FPDGGRTAWQCLATENADGTFRKLGPVLPLPEGYTGHVRDPKVWRQDGRWYMVLGAQDVQ CCCCCCCEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCHHHH QRGKVLLFTASDLREWRLVGEIAGHDVNGLANAGYMWECPDLFPLADTHLLICCPQGLAR HCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCHHHH EAQRFLNTYPAVWMAGRFDAERGIFDHGPLHELDSGFEFYAPQTMQAKDGRRLLVGWMGV HHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHCCCCEECCCCCCCCCCCCEEEEEEECC PDGEEMHQPTRAQGWIHQMTCVRELEWQAGTLYQRPLRELAALRGEAQGWRGQTLPLAPM CCCHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC ELAFDLSPDSTLGLDFAGALQLTVNRDGLRLSRRGLQTAEMHHRYWRGEARRLRIFIDRS EEEEECCCCCCCCCEEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHCCCCEEEEEEEECC SVEIFINDGEGVMSSRFFPGYPGQLIFSGATPVAFCRWLLRPCMVE CEEEEEECCCCHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCC >Mature Secondary Structure SLPSRLPAILQAVMQGQPQALADSHYPQWHLAPVNGLLNDPNGFCQVAGRYHLFYQWNP CCCHHHHHHHHHHHCCCCCHHHCCCCCCEEEEECCCCCCCCCCCEEECCEEEEEEEECC LACDHTYKCWGHWSSADLLHWRHEPIALMPDEEYDRNGCYSGSAVEFEGALTLCYTGNVK CCCCCCEEEECCCCCCCEEEECCCCEEECCCCCCCCCCCCCCCEEEECCEEEEEEECCEE FPDGGRTAWQCLATENADGTFRKLGPVLPLPEGYTGHVRDPKVWRQDGRWYMVLGAQDVQ CCCCCCCEEEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEEEECCHHHH QRGKVLLFTASDLREWRLVGEIAGHDVNGLANAGYMWECPDLFPLADTHLLICCPQGLAR HCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCCEEEEECCCHHHH EAQRFLNTYPAVWMAGRFDAERGIFDHGPLHELDSGFEFYAPQTMQAKDGRRLLVGWMGV HHHHHHHCCCCEEEECCCCCCCCCCCCCCHHHHCCCCEECCCCCCCCCCCCEEEEEEECC PDGEEMHQPTRAQGWIHQMTCVRELEWQAGTLYQRPLRELAALRGEAQGWRGQTLPLAPM CCCHHHCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC ELAFDLSPDSTLGLDFAGALQLTVNRDGLRLSRRGLQTAEMHHRYWRGEARRLRIFIDRS EEEEECCCCCCCCCEEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHCCCCEEEEEEEECC SVEIFINDGEGVMSSRFFPGYPGQLIFSGATPVAFCRWLLRPCMVE CEEEEEECCCCHHHCCCCCCCCCCEEECCCCHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 8628219; 11473129; 8412665 [H]