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The map label for this gene is lyx [H]

Identifier: 238893242

GI number: 238893242

Start: 1084461

End: 1086026

Strand: Reverse

Name: lyx [H]

Synonym: KP1_1111

Alternate gene names: 238893242

Gene position: 1086026-1084461 (Counterclockwise)

Preceding gene: 238893243

Following gene: 238893241

Centisome position: 20.69

GC content: 52.3

Gene sequence:

>1566_bases
ATGGTAACCAATAAGGAGTCCACGCGAATGAAAGATGAATACGTCATGGGCATCGACAATGGTGGAACCGTCACCAAGGC
AGCCATCTATGACCGTAAAGGACAGGTGCTCGCCATCGCCTCAAAATCCACGCAGATGCTGACACCTCGGGAATTCCACA
CAGAGCGCAGTATCGATGAGCTGTGGGCCGCGAATGTCGAAGTGATTAAAAAAGCGATTGAGCAATCAGGTATCGACGCC
AGCCAGATAAAAGGAGTGGCCGTCACCGGTCATGGTAACGGTCTGTATCTGGTCGACGAAGAAGGTCACCCGGTGCGTAA
CGGCATTATATCCACCGATAGCCGGGCAAAAGAGTACGTTGAGAGATGGCAACGCTCGCCAGAATTCCTTACCGACATTT
TGCCAAAAACGATGCAGTCCATCTGGGCCGGACAACCTGTCGCCCTGCTGGCATGGCTGAAGAATTTCGAGCCCGAGACG
CTGCAAAAAGCGCGTTATATTTTTATGGTCAAGGACCTGATCCGTTTTTACCTGACCGGAGAGGCTTTTCTTGAGCTGAC
CGATATCTCAGGGACCAACCTGATCAACGTACGTGACTGCAAGTATGACGATGAACTACTGGCATGGTGGGGACTTGATG
AACTGCGGGACAAATTGCCCCCCATCAAACGCTCAACAGAATGCTGCGGAAAAATCACTGACGACGTGGCCCGTCTGACC
GGTTTATGCGCAGGTACGCCGGTTTCTGGCGGGGTGTTTGATATCTCGGCCTCTTCCATTGCCTCGGGGATTAACAGTCT
CGATAAGATGGCGATCGTCACCGGCACCTGGAGCATAAACGAATACGTTACCGACCACCCGGTTATTGATAAAGATCTGT
TTATGACCTCCATTTATCCCATTGAAGGTAAATGGCTCATCACCGAGGCCAGCCCCACCTCCGCGAGCAACCTGGAGTGG
TTTATTAACAACTTTATGGAGAGCGATCGGAAAACCTCCGCCGAACAAGGATCGTCGGTCTATGACCTGTGTAATAAGCT
GGTTTCATCAACGACGCCGGATGAAAGCCACCTGCTGTTCTTTCCGTTCGTGTTTGGCTCTAACACCATTCCCGACGCCT
CGGCCGGCTTTATCGGTGTCAACAGCTTCCATAAAAAAGCCCATTTTCTGCGGGCGATTTATGAGGGCGTTGCCTTCAGC
CATCTCTACCACACCGAGCGCTTACGCAATATTAACCCGAAGCTAAGCCGCACTATTCGTATTGCTGGCGGCGTCACGAA
CTCCCCGGTCTGGCTGCAGATATTCGCCGATATCTTCCAGGCCACGCTGGAAATCGTTGACGTCAAAGAGCACGGGACCC
TGGGTACCGCGATGACCGCCGCCGTTATGGTGGGCTGGTTTGCGGAGGTATTTGCTGCCTCAAACGACATGGTCCATGTC
TCACGCACCGTCTCCCCTAATCCGGAAAACCACCGGGTCTACCAGACCAAATACCAGCTTTATAAAAACCTGTTATCAGA
AATGCAGTCGCCGTGGAAAAGCTGCAGCAACTACATCGCGCACTAA

Upstream 100 bases:

>100_bases
ATGTGGTATTCATAGCCGGAGGCTTTGTTAAGCGCAAATACCTTGTAGATAAAATATTCCATGCCGGATTTAAAGGGATA
ACCACCAGCGAGCCCGGCTT

Downstream 100 bases:

>100_bases
GTGAGGAAAAAATGGATCTGAATTTAACGAATCGTACGGCCATCGTGACAGGCGGCGCAACCGGCCTGGGGAAAGAGTTT
GTTCTTTCTCTCGCCAAAGA

Product: putative L-xylulose kinase

Products: NA

Alternate protein names: L-xylulokinase [H]

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MVTNKESTRMKDEYVMGIDNGGTVTKAAIYDRKGQVLAIASKSTQMLTPREFHTERSIDELWAANVEVIKKAIEQSGIDA
SQIKGVAVTGHGNGLYLVDEEGHPVRNGIISTDSRAKEYVERWQRSPEFLTDILPKTMQSIWAGQPVALLAWLKNFEPET
LQKARYIFMVKDLIRFYLTGEAFLELTDISGTNLINVRDCKYDDELLAWWGLDELRDKLPPIKRSTECCGKITDDVARLT
GLCAGTPVSGGVFDISASSIASGINSLDKMAIVTGTWSINEYVTDHPVIDKDLFMTSIYPIEGKWLITEASPTSASNLEW
FINNFMESDRKTSAEQGSSVYDLCNKLVSSTTPDESHLLFFPFVFGSNTIPDASAGFIGVNSFHKKAHFLRAIYEGVAFS
HLYHTERLRNINPKLSRTIRIAGGVTNSPVWLQIFADIFQATLEIVDVKEHGTLGTAMTAAVMVGWFAEVFAASNDMVHV
SRTVSPNPENHRVYQTKYQLYKNLLSEMQSPWKSCSNYIAH

Sequences:

>Translated_521_residues
MVTNKESTRMKDEYVMGIDNGGTVTKAAIYDRKGQVLAIASKSTQMLTPREFHTERSIDELWAANVEVIKKAIEQSGIDA
SQIKGVAVTGHGNGLYLVDEEGHPVRNGIISTDSRAKEYVERWQRSPEFLTDILPKTMQSIWAGQPVALLAWLKNFEPET
LQKARYIFMVKDLIRFYLTGEAFLELTDISGTNLINVRDCKYDDELLAWWGLDELRDKLPPIKRSTECCGKITDDVARLT
GLCAGTPVSGGVFDISASSIASGINSLDKMAIVTGTWSINEYVTDHPVIDKDLFMTSIYPIEGKWLITEASPTSASNLEW
FINNFMESDRKTSAEQGSSVYDLCNKLVSSTTPDESHLLFFPFVFGSNTIPDASAGFIGVNSFHKKAHFLRAIYEGVAFS
HLYHTERLRNINPKLSRTIRIAGGVTNSPVWLQIFADIFQATLEIVDVKEHGTLGTAMTAAVMVGWFAEVFAASNDMVHV
SRTVSPNPENHRVYQTKYQLYKNLLSEMQSPWKSCSNYIAH
>Mature_521_residues
MVTNKESTRMKDEYVMGIDNGGTVTKAAIYDRKGQVLAIASKSTQMLTPREFHTERSIDELWAANVEVIKKAIEQSGIDA
SQIKGVAVTGHGNGLYLVDEEGHPVRNGIISTDSRAKEYVERWQRSPEFLTDILPKTMQSIWAGQPVALLAWLKNFEPET
LQKARYIFMVKDLIRFYLTGEAFLELTDISGTNLINVRDCKYDDELLAWWGLDELRDKLPPIKRSTECCGKITDDVARLT
GLCAGTPVSGGVFDISASSIASGINSLDKMAIVTGTWSINEYVTDHPVIDKDLFMTSIYPIEGKWLITEASPTSASNLEW
FINNFMESDRKTSAEQGSSVYDLCNKLVSSTTPDESHLLFFPFVFGSNTIPDASAGFIGVNSFHKKAHFLRAIYEGVAFS
HLYHTERLRNINPKLSRTIRIAGGVTNSPVWLQIFADIFQATLEIVDVKEHGTLGTAMTAAVMVGWFAEVFAASNDMVHV
SRTVSPNPENHRVYQTKYQLYKNLLSEMQSPWKSCSNYIAH

Specific function: L-lyxose utilization. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI164663828, Length=553, Percent_Identity=23.1464737793852, Blast_Score=103, Evalue=4e-22,
Organism=Homo sapiens, GI164663830, Length=577, Percent_Identity=22.1837088388215, Blast_Score=96, Evalue=6e-20,
Organism=Escherichia coli, GI1790005, Length=507, Percent_Identity=37.0808678500986, Blast_Score=355, Evalue=3e-99,
Organism=Escherichia coli, GI1787789, Length=494, Percent_Identity=25.1012145748988, Blast_Score=145, Evalue=9e-36,
Organism=Escherichia coli, GI1789987, Length=506, Percent_Identity=21.5415019762846, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1789168, Length=477, Percent_Identity=22.2222222222222, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789138, Length=511, Percent_Identity=21.9178082191781, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790361, Length=502, Percent_Identity=21.1155378486056, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24657106, Length=540, Percent_Identity=23.3333333333333, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24657102, Length=540, Percent_Identity=23.3333333333333, Blast_Score=89, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.53 [H]

Molecular weight: Translated: 58185; Mature: 58185

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTNKESTRMKDEYVMGIDNGGTVTKAAIYDRKGQVLAIASKSTQMLTPREFHTERSIDE
CCCCCCHHCCCCCEEEEECCCCCEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHCCHHH
LWAANVEVIKKAIEQSGIDASQIKGVAVTGHGNGLYLVDEEGHPVRNGIISTDSRAKEYV
HHHCCHHHHHHHHHHCCCCHHHCCCEEEEECCCEEEEECCCCCHHHCCCCCCCHHHHHHH
ERWQRSPEFLTDILPKTMQSIWAGQPVALLAWLKNFEPETLQKARYIFMVKDLIRFYLTG
HHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
EAFLELTDISGTNLINVRDCKYDDELLAWWGLDELRDKLPPIKRSTECCGKITDDVARLT
CCEEEEEECCCCCEEEEECCCCCCHHHEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GLCAGTPVSGGVFDISASSIASGINSLDKMAIVTGTWSINEYVTDHPVIDKDLFMTSIYP
HHHCCCCCCCCEEECCHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCHHHHHHEEEE
IEGKWLITEASPTSASNLEWFINNFMESDRKTSAEQGSSVYDLCNKLVSSTTPDESHLLF
ECCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCCCCCCEEE
FPFVFGSNTIPDASAGFIGVNSFHKKAHFLRAIYEGVAFSHLYHTERLRNINPKLSRTIR
EEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEE
IAGGVTNSPVWLQIFADIFQATLEIVDVKEHGTLGTAMTAAVMVGWFAEVFAASNDMVHV
EECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
SRTVSPNPENHRVYQTKYQLYKNLLSEMQSPWKSCSNYIAH
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVTNKESTRMKDEYVMGIDNGGTVTKAAIYDRKGQVLAIASKSTQMLTPREFHTERSIDE
CCCCCCHHCCCCCEEEEECCCCCEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHCCHHH
LWAANVEVIKKAIEQSGIDASQIKGVAVTGHGNGLYLVDEEGHPVRNGIISTDSRAKEYV
HHHCCHHHHHHHHHHCCCCHHHCCCEEEEECCCEEEEECCCCCHHHCCCCCCCHHHHHHH
ERWQRSPEFLTDILPKTMQSIWAGQPVALLAWLKNFEPETLQKARYIFMVKDLIRFYLTG
HHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
EAFLELTDISGTNLINVRDCKYDDELLAWWGLDELRDKLPPIKRSTECCGKITDDVARLT
CCEEEEEECCCCCEEEEECCCCCCHHHEECCHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
GLCAGTPVSGGVFDISASSIASGINSLDKMAIVTGTWSINEYVTDHPVIDKDLFMTSIYP
HHHCCCCCCCCEEECCHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCHHHHHHEEEE
IEGKWLITEASPTSASNLEWFINNFMESDRKTSAEQGSSVYDLCNKLVSSTTPDESHLLF
ECCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHCCCCCCCCEEE
FPFVFGSNTIPDASAGFIGVNSFHKKAHFLRAIYEGVAFSHLYHTERLRNINPKLSRTIR
EEEEECCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEE
IAGGVTNSPVWLQIFADIFQATLEIVDVKEHGTLGTAMTAAVMVGWFAEVFAASNDMVHV
EECCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEE
SRTVSPNPENHRVYQTKYQLYKNLLSEMQSPWKSCSNYIAH
EEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]