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The map label for this gene is fhuA [H]

Identifier: 238893148

GI number: 238893148

Start: 981000

End: 983207

Strand: Direct

Name: fhuA [H]

Synonym: KP1_1002

Alternate gene names: 238893148

Gene position: 981000-983207 (Clockwise)

Preceding gene: 238893147

Following gene: 238893149

Centisome position: 18.69

GC content: 59.19

Gene sequence:

>2208_bases
ATGGCGCGTCCAAAAACTGCTCAGCCAAATCACTCGCTGCGTAAAGTCGCAGCTGTAGTAGCCACGGCGGTTAGCGGCAT
GTCTGTCTACGCACAGGCAGCAGAACAACCGAAGCAAGAAGAAACTATCACCGTCGTTGCCGCCCCGGCCGCCCAGGAAA
GCGCCTGGGGACCGGCGCCGACTATCGCGGCAAAACGCTCCGCCACGGCGACCAAAACCGATACCCCGATTGAAAAAACG
CCGCAGTCTGTGTCGGTGGTGACGCGCCAGGAGATGGAGATGCGCCAGCCGACGACGGTAAAAGAGGCGCTCTCCTATAC
GCCAAGCGTCTTCTCTACTCGCGGCAGTTCGACCACCTATGACGTGGTCACCATTCGCGGCTTCACCACCTCGACGACCG
TCAACACCAACCAGTATCTGGACGGCATGAAGCTGCAGGGGAATAACTACTCTGAAGTCTCCATGGATCCTTACTTCCTC
GAGCGTGTGGAAGTGATGCGCGGGCCAACCTCGGTGCTGTACGGCAACAGCAACCCGGGCGGTATCGTCAGCATGGTCAG
CAAGCGCCCGACTACCGAGCCGCTGAAAGAAGTGCAGTTTAAGATGGGCACCGACAATCTGTGGCAGACCGGGTTTGACT
TTAGCGACGCCATTGATGATGCCGGCGTTTGGTCGTATCGCCTGACCGGCCTTGGCCGCAGTCAGGATGCCCAGCAGCAG
ATGGCGAAATCGACCCGCTACGCGGTGGCGCCCTCCTTTAGCTGGCGTCCGGACGATAAAACTGACTTCACCTTCCTGAG
CAACTTCCAGAATGACCCGGATGCGGGCTACTACGGCTGGCTGCCGCGCGAAGGCACCGTGGTGCCGTATTACGACGCCA
ACGGTAAGGCGCACAAGCTGCCGACCGATTTCAACGAAGGCGAGTCCGATAATAAAATCTCCCGCCGCCAGAAGATGGTG
GGCTACAGCTTCTCCCATCAGTTCGATGACACCTTTACCGTGCGGCAGAACCTGCGCTATGCCGATGTGCATACGCTCTA
TCGTTCGGTATACGGCAACGGCTATGTCGCGCCGGGCTACATGAATCGCGCCTACGTGCGCTCCGACGAGCACCTGAACA
CCTTCACCGTCGATACCCAGCTGCAGTCTGATTTCGCCACCGGCGCGGTCAGCCATACGCTGCTGACCGGCGTGGACTAC
TCGCGGATGCGTAACGATGTGGATGCCGACTACGGGACGGCGGATCCTATCAGCATGAGCAATCCGCAGTACGGCAATCC
GAATATTCAGGTCACCTTCCCGTACGCGGTCCTCAACCGGATGGAGCAGACCGGCCTGTACGCGCAGGATCAGATGGAGT
GGGATAAATGGGTGATGACCCTGGGCGGCCGTTACGATTACGCCACGACCTCAACGTTAACCCGCGCCACCAACAGCCTG
GCGGAGAATCACGACCAGCAGTTCAGCTGGCGCGGCGGCATCAACTACCTGTTCGATAACGGCATCTCTCCGTACTTCAG
CTACAGCGAATCGTTTGAACCGGTATCGGGTTCTAACAGCCGCGGCCAGCCGTTCGATCCGTCGCGCGGTAAGCAGTATG
AAGCCGGCGTGAAATACGTGCCGAAAGATATGCCGGTGGTGGTCACCGCGGCGGTCTATCAGCTGACCAAAGACAAGAAC
CTGACGGCTGATCCGGCTAACCAGGCGTTCAGCATCCAGACCGGCGAGATCCGCTCCCGCGGCCTTGAGCTGGAGGCGAA
GGCGGCGGTGAACGCCAATATTAACGTCACCGCGGCCTACAGCTACACCGATGCGGAGTACACTCACGATACGGTGTTCA
ACGGCAAACGTCCGGCGGAAGTGCCGCGTAACATGGCCTCCCTGTGGGCGGATTATACCTTCCACGAAACCGCGCTGAGC
GGTCTGACGATTGGGGCCGGGGCGCGCTATATCGGTTCAACGGTCAGCTACTACAAAAATGACACCAGCACCGGTAAGAA
AAATGATGCCTTTAGTGTGGCCGGTTATGCGCTGATGGATGCGACGGTGAAATACGATCTGGCGCGCTTTGGCCTGCCGG
GATCGTCGGTCGGCGTCAACGTCAACAACCTGTTCGACCGCGAATATGTCTCCAGTTGCTACAGCGAATACGCCTGCTAC
TGGGGGGCCGGACGTCAGGTCGTCGCCACCGCCACCTTCCGTTTCTAA

Upstream 100 bases:

>100_bases
CATATCGCTTGCCTTGCCTTCGACGTTTCGCCTATTATATCGCCCGTCATAATAATAATTCTCGTTTACGTTATCATTCA
CTTTCATCAGAGATATACCC

Downstream 100 bases:

>100_bases
CCACCTACGGGCGCGGTTCGCCGCGCCCTCTATCAGGTTATCGCTATGCAGGAACAGACTCCGCACGCAGAAACCACCTT
CGCGCTGGATCGCGTCACTT

Product: ferrichrome outer membrane transporter

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 735; Mature: 734

Protein sequence:

>735_residues
MARPKTAQPNHSLRKVAAVVATAVSGMSVYAQAAEQPKQEETITVVAAPAAQESAWGPAPTIAAKRSATATKTDTPIEKT
PQSVSVVTRQEMEMRQPTTVKEALSYTPSVFSTRGSSTTYDVVTIRGFTTSTTVNTNQYLDGMKLQGNNYSEVSMDPYFL
ERVEVMRGPTSVLYGNSNPGGIVSMVSKRPTTEPLKEVQFKMGTDNLWQTGFDFSDAIDDAGVWSYRLTGLGRSQDAQQQ
MAKSTRYAVAPSFSWRPDDKTDFTFLSNFQNDPDAGYYGWLPREGTVVPYYDANGKAHKLPTDFNEGESDNKISRRQKMV
GYSFSHQFDDTFTVRQNLRYADVHTLYRSVYGNGYVAPGYMNRAYVRSDEHLNTFTVDTQLQSDFATGAVSHTLLTGVDY
SRMRNDVDADYGTADPISMSNPQYGNPNIQVTFPYAVLNRMEQTGLYAQDQMEWDKWVMTLGGRYDYATTSTLTRATNSL
AENHDQQFSWRGGINYLFDNGISPYFSYSESFEPVSGSNSRGQPFDPSRGKQYEAGVKYVPKDMPVVVTAAVYQLTKDKN
LTADPANQAFSIQTGEIRSRGLELEAKAAVNANINVTAAYSYTDAEYTHDTVFNGKRPAEVPRNMASLWADYTFHETALS
GLTIGAGARYIGSTVSYYKNDTSTGKKNDAFSVAGYALMDATVKYDLARFGLPGSSVGVNVNNLFDREYVSSCYSEYACY
WGAGRQVVATATFRF

Sequences:

>Translated_735_residues
MARPKTAQPNHSLRKVAAVVATAVSGMSVYAQAAEQPKQEETITVVAAPAAQESAWGPAPTIAAKRSATATKTDTPIEKT
PQSVSVVTRQEMEMRQPTTVKEALSYTPSVFSTRGSSTTYDVVTIRGFTTSTTVNTNQYLDGMKLQGNNYSEVSMDPYFL
ERVEVMRGPTSVLYGNSNPGGIVSMVSKRPTTEPLKEVQFKMGTDNLWQTGFDFSDAIDDAGVWSYRLTGLGRSQDAQQQ
MAKSTRYAVAPSFSWRPDDKTDFTFLSNFQNDPDAGYYGWLPREGTVVPYYDANGKAHKLPTDFNEGESDNKISRRQKMV
GYSFSHQFDDTFTVRQNLRYADVHTLYRSVYGNGYVAPGYMNRAYVRSDEHLNTFTVDTQLQSDFATGAVSHTLLTGVDY
SRMRNDVDADYGTADPISMSNPQYGNPNIQVTFPYAVLNRMEQTGLYAQDQMEWDKWVMTLGGRYDYATTSTLTRATNSL
AENHDQQFSWRGGINYLFDNGISPYFSYSESFEPVSGSNSRGQPFDPSRGKQYEAGVKYVPKDMPVVVTAAVYQLTKDKN
LTADPANQAFSIQTGEIRSRGLELEAKAAVNANINVTAAYSYTDAEYTHDTVFNGKRPAEVPRNMASLWADYTFHETALS
GLTIGAGARYIGSTVSYYKNDTSTGKKNDAFSVAGYALMDATVKYDLARFGLPGSSVGVNVNNLFDREYVSSCYSEYACY
WGAGRQVVATATFRF
>Mature_734_residues
ARPKTAQPNHSLRKVAAVVATAVSGMSVYAQAAEQPKQEETITVVAAPAAQESAWGPAPTIAAKRSATATKTDTPIEKTP
QSVSVVTRQEMEMRQPTTVKEALSYTPSVFSTRGSSTTYDVVTIRGFTTSTTVNTNQYLDGMKLQGNNYSEVSMDPYFLE
RVEVMRGPTSVLYGNSNPGGIVSMVSKRPTTEPLKEVQFKMGTDNLWQTGFDFSDAIDDAGVWSYRLTGLGRSQDAQQQM
AKSTRYAVAPSFSWRPDDKTDFTFLSNFQNDPDAGYYGWLPREGTVVPYYDANGKAHKLPTDFNEGESDNKISRRQKMVG
YSFSHQFDDTFTVRQNLRYADVHTLYRSVYGNGYVAPGYMNRAYVRSDEHLNTFTVDTQLQSDFATGAVSHTLLTGVDYS
RMRNDVDADYGTADPISMSNPQYGNPNIQVTFPYAVLNRMEQTGLYAQDQMEWDKWVMTLGGRYDYATTSTLTRATNSLA
ENHDQQFSWRGGINYLFDNGISPYFSYSESFEPVSGSNSRGQPFDPSRGKQYEAGVKYVPKDMPVVVTAAVYQLTKDKNL
TADPANQAFSIQTGEIRSRGLELEAKAAVNANINVTAAYSYTDAEYTHDTVFNGKRPAEVPRNMASLWADYTFHETALSG
LTIGAGARYIGSTVSYYKNDTSTGKKNDAFSVAGYALMDATVKYDLARFGLPGSSVGVNVNNLFDREYVSSCYSEYACYW
GAGRQVVATATFRF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=763, Percent_Identity=60.9436435124508, Blast_Score=913, Evalue=0.0,
Organism=Escherichia coli, GI1787024, Length=802, Percent_Identity=25.5610972568579, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1787344, Length=764, Percent_Identity=24.869109947644, Blast_Score=112, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 81382; Mature: 81250

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARPKTAQPNHSLRKVAAVVATAVSGMSVYAQAAEQPKQEETITVVAAPAAQESAWGPAP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCC
TIAAKRSATATKTDTPIEKTPQSVSVVTRQEMEMRQPTTVKEALSYTPSVFSTRGSSTTY
CHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCEE
DVVTIRGFTTSTTVNTNQYLDGMKLQGNNYSEVSMDPYFLERVEVMRGPTSVLYGNSNPG
EEEEEECEEEEEEECHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCC
GIVSMVSKRPTTEPLKEVQFKMGTDNLWQTGFDFSDAIDDAGVWSYRLTGLGRSQDAQQQ
CCEEEECCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHHCCCCCEEEEEECCCCCHHHHHH
MAKSTRYAVAPSFSWRPDDKTDFTFLSNFQNDPDAGYYGWLPREGTVVPYYDANGKAHKL
HHHHCCEEECCCCCCCCCCCCCHHHHHCCCCCCCCCEECCCCCCCCEEEEECCCCCCCCC
PTDFNEGESDNKISRRQKMVGYSFSHQFDDTFTVRQNLRYADVHTLYRSVYGNGYVAPGY
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCEECCCC
MNRAYVRSDEHLNTFTVDTQLQSDFATGAVSHTLLTGVDYSRMRNDVDADYGTADPISMS
CCCEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCC
NPQYGNPNIQVTFPYAVLNRMEQTGLYAQDQMEWDKWVMTLGGRYDYATTSTLTRATNSL
CCCCCCCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AENHDQQFSWRGGINYLFDNGISPYFSYSESFEPVSGSNSRGQPFDPSRGKQYEAGVKYV
HHCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PKDMPVVVTAAVYQLTKDKNLTADPANQAFSIQTGEIRSRGLELEAKAAVNANINVTAAY
CCCCCEEEEHHHHHHHCCCCCCCCCCCCEEEEECCHHHHCCCCEEEEEEECCCEEEEEEE
SYTDAEYTHDTVFNGKRPAEVPRNMASLWADYTFHETALSGLTIGAGARYIGSTVSYYKN
EECCCCCCCHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHCCEEECCCCHHHHCHHHHHCC
DTSTGKKNDAFSVAGYALMDATVKYDLARFGLPGSSVGVNVNNLFDREYVSSCYSEYACY
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHEE
WGAGRQVVATATFRF
ECCCCEEEEEEEECC
>Mature Secondary Structure 
ARPKTAQPNHSLRKVAAVVATAVSGMSVYAQAAEQPKQEETITVVAAPAAQESAWGPAP
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCC
TIAAKRSATATKTDTPIEKTPQSVSVVTRQEMEMRQPTTVKEALSYTPSVFSTRGSSTTY
CHHCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHHHCCCCCCCEE
DVVTIRGFTTSTTVNTNQYLDGMKLQGNNYSEVSMDPYFLERVEVMRGPTSVLYGNSNPG
EEEEEECEEEEEEECHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCC
GIVSMVSKRPTTEPLKEVQFKMGTDNLWQTGFDFSDAIDDAGVWSYRLTGLGRSQDAQQQ
CCEEEECCCCCCCHHHHHHHHCCCCHHHHCCCCHHHHHCCCCCEEEEEECCCCCHHHHHH
MAKSTRYAVAPSFSWRPDDKTDFTFLSNFQNDPDAGYYGWLPREGTVVPYYDANGKAHKL
HHHHCCEEECCCCCCCCCCCCCHHHHHCCCCCCCCCEECCCCCCCCEEEEECCCCCCCCC
PTDFNEGESDNKISRRQKMVGYSFSHQFDDTFTVRQNLRYADVHTLYRSVYGNGYVAPGY
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHCCCEECCCC
MNRAYVRSDEHLNTFTVDTQLQSDFATGAVSHTLLTGVDYSRMRNDVDADYGTADPISMS
CCCEEECCCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCC
NPQYGNPNIQVTFPYAVLNRMEQTGLYAQDQMEWDKWVMTLGGRYDYATTSTLTRATNSL
CCCCCCCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
AENHDQQFSWRGGINYLFDNGISPYFSYSESFEPVSGSNSRGQPFDPSRGKQYEAGVKYV
HHCCCCCEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PKDMPVVVTAAVYQLTKDKNLTADPANQAFSIQTGEIRSRGLELEAKAAVNANINVTAAY
CCCCCEEEEHHHHHHHCCCCCCCCCCCCEEEEECCHHHHCCCCEEEEEEECCCEEEEEEE
SYTDAEYTHDTVFNGKRPAEVPRNMASLWADYTFHETALSGLTIGAGARYIGSTVSYYKN
EECCCCCCCHHHCCCCCCHHHHHHHHHHHHCCHHHHHHHCCEEECCCCHHHHCHHHHHCC
DTSTGKKNDAFSVAGYALMDATVKYDLARFGLPGSSVGVNVNNLFDREYVSSCYSEYACY
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHEE
WGAGRQVVATATFRF
ECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]