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The map label for this gene is lgrB [H]

Identifier: 339905965

GI number: 339905965

Start: 1872818

End: 1876306

Strand: Direct

Name: lgrB [H]

Synonym: NA

Alternate gene names: 339905965

Gene position: 1872818-1876306 (Clockwise)

Preceding gene: 238027303

Following gene: 238027305

Centisome position: 47.94

GC content: 72.28

Gene sequence:

>3489_bases
ATGACCCAATCCGCACCATCCGTCTATGCCCAGTTCGAGCAGGCCTGCGCCGCGCAGCCCGACGCGCTCGCGCTGGAAGG
CCCGTCCGGGCAGCTCAGCTACGCCGGACTGCTGGCGAGCGTCGCCGCGATCGGCACGCGGCTCGCCGAGGCGGGCGTCA
CCCCCGGCACCCTCGTCGGCGTGTTGCTGCCGCGCGATTTCCGGCTGCCCGCCGCGATCCTCGCCGCGTTCGGCTCGCAG
GCCGTGTATGTGCCGCTCACCGAGAAATATCCGCCCGAGCGGATCCGCGAGATCGTCCTGAGCCATCGCATCACCCATGT
GGTGACCAGCCAGGCCCTGACCGCGCTGCTGCCGCCCGAGTGCCGCGCGATCGTGCTGCCGTCCGAACCCGGCGCGGCGC
AGGGGGCGGGCTGGCGTCCCGCCGCGCCGCGCGGCGACGACGCCCCGGCCTATGTGGTGTTTACCTCCGGCTCGACCGGC
ACGCCCAAGGGCGTGCTGATCGGCGAGGCGAGCCTGCGCAACCTGATCGACTGGTATCGCGCCGCCTATCGCCCCGACGA
GCGCCGCGCGGTGCTGGCCTCGACGCAGATCACCTTCGACCTGTCGCTCTTCGAGCTGGTCTGCACCCTCTGCTCCGGCA
GCAAGGTGGTGCTCGTCGACTCGATCCTGCAGTTGCTCGAGGCCGATGCGCAATTCGACGTCAGCCTGATCAACACGGTG
CCGTCCGCCGCTCGGGAGCTGGTGCGTCGCCGCCGCTTCCCGGCCGCGACGCGGGTCGTCAACCTGGCCGGCGAGGCGCT
GTACCAGGATCTGGTCGACGCGATCCACGACGCCGCGCCGCAGGTGCGGCAGGTCTATAACCTCTACGGCCCGTCCGAGG
ACACCACCTATTCGACCGGCCATGCCGTACCGCGCCACGGCAGCAGCCGTACCGTCAGCATCGGCCGCTCGCTGCCGGGC
AAGACCGCGCACCTGCTCGACGACGCCCTGATGCCGGTCGAGCCCGGCGCGGTCGGCGAGATCTGCCTGAGCGGCGAGGG
CGTCGCGCTCGGCTACCTGAACGACCCGCGGCTCACCGAGCAGAAATTCCCGACCGTCGCGCAGGGCCCCTTGAAGGGGC
TGCGCCTGTATCGCACCGGCGATCTCGGGCAGTTCGACGACGACGGCCTGCTGCGCTACCTCGGCCGCGCCGATCGGCAG
GTCAAGGTGCGCGGCGTGCGCATCGAGCCCGGCGAGGTCGAGGTCGCGCTGCGCGGCATCGCGGGCGTGGCCGACGCGGC
GGTGGTGAAGGTCGTCGATCCCTCGGGCAACGACCAGCTCGTCGCGCTGGTGGTGCCCCAGCCGGGCCAGGTGCCGGGAC
ACGAGATCCTCGATCAGTTGCAGAGCCGCCTGCCGGCCTTCATGGTGCCCTCGCGGGTCGAGCCGATCGCGGCGATCCCG
CTGAACGGCAACGGCAAGACCGACCGCACCGCACTGGAGCGGATCGCCTCGGCGTGCTATCGCGCCGAGCCGGCCGTCGA
CGATCTCGCAGAGCAGGTCCGCGAGGTGGTCGCCACGCTGATGGCACGCACCGACGTGGCGAGCGACACCGACTTTTTCC
GGATCGGCGGCAACTCGCTGCTGAGCGCCCAGCTGACCTTTCTGCTGCAGCAGCGCTTCGCCGTGACGGTCAGCATCGCC
GACGTGTTCCGCCTGCGCACGCCGGCCGCGCTGGCGGCCGCGATCGGCTCGCGGCGCGCGGCGAATCAGCCCGCCGAGGC
ACGGTCAGCCGCGCCGGCACCGTCGCCGGCGGCTGCGGTCGCGGCACCCGTGGCGCCCCCCGCCGCGCCGGCGCCCGCGC
AGCCGCGCGAGGGTGCGGGCGGGCCGGCCGTGGGCGGCACGCTCGCTACCGCGGCCCAGCGCGGCATCTGGCTGCTGGAG
AACAGCCCCGGCGGGCGGGCCGTGTCGAATGCTCCGCTGGTATTCGACTACAGCGGCACGCTCGAGCGCGCGCGGCTCGC
GCGCTGCGTCACGCACTGGCTGGCCCGCCATCCGATCCTGCGCAGCACCTATGCCTGGGAGGACGGCGCCCTGCGGATCC
GCGAGCGCGAGGCCGCGCCGTTCGTGCTCGCCAGCGTCGACCTGCGTGCCGAGCCGGATGAGCAGCGCATGGTGCGCGCC
GAGGCGCTGATCGCGGCCGAGGCGATGCGGCCCTTCGATCTGCGCCACGATCCGATGCTGCGCGTGACCGAGCTGCGGCT
CGGCGATCATGCCGGGCGGCTGATCTTCGTGTTCCATCACATCGCGGTGGACGACCGCGCGATGAACGTCCTGTTCGCCG
AACTGGAGCGGGACTACCGGGCCGGCGACGCGCCGCTGGCGGTGGACGCCGCGCCCGCGCGCCGGTTCGCCGACTTCGCC
GCCGAGACACGCGGCGGCACGGCGGCGCACGCCGATCTGGCCTACTGGGTCGAGCAGCTGCGCGACTATCGCGGCGCGAC
CGCCTACCTGGTCGCGCCCGACGCGAAGCCGGTCGCGCGCTTTGCCGGCCGGCTCCATCACCACCGGCTGCCGGCCGCGA
TCAGCCGCGATTTCGAGGCAGCCGCCGCGCGCCGCGCGGTGACGCCTTTCGCGCTGTTCACCACCGCCGTGACCGCGCTG
CTGCGGCACGGCGCCGGCACCGAGGACGTGACGATCGGTTCGTTCTTCTCGCAGCGCGACCATTTCGCCGACGGCGAGCT
GGTGGGTTTCTTCGTCAACACGCTGCCGCTGCGGGTGCGCAGCGGTGCCGACTGGGATCTGGACCGGCTCGCCCAGGCGG
TGGCGCTCACCCTCGCCGACGCGCAGACGCATCGCCACGTGGCCGCCGAGGACATCTTCGACGCGCTGCAGGCCAGCACC
GCGCTGCGGCGCGCGGCCTTCCGCGTGATGGTGAACCTGGAGCCGGAGCAGGCCGAAACGCTGGAGATGGACGGCTTCAC
GGCGCGCCGGGTGCCGCTCGATCGCGGCGTGGCCAAGTACGACCTGCTGTTTTCCCTGCGCAAGGAGGAGGGCAGCTACC
GCGTGCTGGTCGAGTACCACACCGAGCTTTACAGCGAGACGCTGATCGCGCGGATCTGCGCGAATCTCGACCGCGTGCTC
GCCGCGCTCACGGGTACGGCGCGCGTCGCGCTGGCCGCGCTCGCGCTGCCGGATCCGCGCGACGAGGCGGCCTGGAGCGC
GGCGCCGACGGACGACGGCGGCGCCGCGGCGCCGGCCGATTTCCGCACCCTGGTGCGCGAGATCTGGGCCGGCGAGGTCG
GGCATGGAGATTTCGGCGACGGCGAGAATTTCTTCGACGTCGGCGGCAGTTCGCTCAAGATCATGTCGGTCTACGAAACC
CTGTCGCAGCGCCTCGCCGAGCGCGGCATCGACAAGGAACTCGACATCGTCGCGCTGTTCGAGCATGTCACCGTCGGCAC
GCTGGCCGACTTCCTGGAGGAATGGACCGCCCATGACGCACTCGCATGA

Upstream 100 bases:
NA

Downstream 100 bases:
NA

Product: putative non-ribosomal peptide synthase/polyketide synthase

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-leucine adenylase; D-LeuA; D-leucine activase; Leucine racemase [ATP-hydrolyzing]; ATP-dependent alanine adenylase; AlaA; Alanine activase; ATP-dependent D-valine adenylase; D-ValA; D-valine activase; Valine racemase [ATP-hydrolyzing] [H]

Number of amino acids: Translated: 1162; Mature: 1161

Protein sequence:
NA

Sequences:

>Translated_1162_residues
MTQSAPSVYAQFEQACAAQPDALALEGPSGQLSYAGLLASVAAIGTRLAEAGVTPGTLVGVLLPRDFRLPAAILAAFGSQ
AVYVPLTEKYPPERIREIVLSHRITHVVTSQALTALLPPECRAIVLPSEPGAAQGAGWRPAAPRGDDAPAYVVFTSGSTG
TPKGVLIGEASLRNLIDWYRAAYRPDERRAVLASTQITFDLSLFELVCTLCSGSKVVLVDSILQLLEADAQFDVSLINTV
PSAARELVRRRRFPAATRVVNLAGEALYQDLVDAIHDAAPQVRQVYNLYGPSEDTTYSTGHAVPRHGSSRTVSIGRSLPG
KTAHLLDDALMPVEPGAVGEICLSGEGVALGYLNDPRLTEQKFPTVAQGPLKGLRLYRTGDLGQFDDDGLLRYLGRADRQ
VKVRGVRIEPGEVEVALRGIAGVADAAVVKVVDPSGNDQLVALVVPQPGQVPGHEILDQLQSRLPAFMVPSRVEPIAAIP
LNGNGKTDRTALERIASACYRAEPAVDDLAEQVREVVATLMARTDVASDTDFFRIGGNSLLSAQLTFLLQQRFAVTVSIA
DVFRLRTPAALAAAIGSRRAANQPAEARSAAPAPSPAAAVAAPVAPPAAPAPAQPREGAGGPAVGGTLATAAQRGIWLLE
NSPGGRAVSNAPLVFDYSGTLERARLARCVTHWLARHPILRSTYAWEDGALRIREREAAPFVLASVDLRAEPDEQRMVRA
EALIAAEAMRPFDLRHDPMLRVTELRLGDHAGRLIFVFHHIAVDDRAMNVLFAELERDYRAGDAPLAVDAAPARRFADFA
AETRGGTAAHADLAYWVEQLRDYRGATAYLVAPDAKPVARFAGRLHHHRLPAAISRDFEAAAARRAVTPFALFTTAVTAL
LRHGAGTEDVTIGSFFSQRDHFADGELVGFFVNTLPLRVRSGADWDLDRLAQAVALTLADAQTHRHVAAEDIFDALQAST
ALRRAAFRVMVNLEPEQAETLEMDGFTARRVPLDRGVAKYDLLFSLRKEEGSYRVLVEYHTELYSETLIARICANLDRVL
AALTGTARVALAALALPDPRDEAAWSAAPTDDGGAAAPADFRTLVREIWAGEVGHGDFGDGENFFDVGGSSLKIMSVYET
LSQRLAERGIDKELDIVALFEHVTVGTLADFLEEWTAHDALA
>Mature_1161_residues
TQSAPSVYAQFEQACAAQPDALALEGPSGQLSYAGLLASVAAIGTRLAEAGVTPGTLVGVLLPRDFRLPAAILAAFGSQA
VYVPLTEKYPPERIREIVLSHRITHVVTSQALTALLPPECRAIVLPSEPGAAQGAGWRPAAPRGDDAPAYVVFTSGSTGT
PKGVLIGEASLRNLIDWYRAAYRPDERRAVLASTQITFDLSLFELVCTLCSGSKVVLVDSILQLLEADAQFDVSLINTVP
SAARELVRRRRFPAATRVVNLAGEALYQDLVDAIHDAAPQVRQVYNLYGPSEDTTYSTGHAVPRHGSSRTVSIGRSLPGK
TAHLLDDALMPVEPGAVGEICLSGEGVALGYLNDPRLTEQKFPTVAQGPLKGLRLYRTGDLGQFDDDGLLRYLGRADRQV
KVRGVRIEPGEVEVALRGIAGVADAAVVKVVDPSGNDQLVALVVPQPGQVPGHEILDQLQSRLPAFMVPSRVEPIAAIPL
NGNGKTDRTALERIASACYRAEPAVDDLAEQVREVVATLMARTDVASDTDFFRIGGNSLLSAQLTFLLQQRFAVTVSIAD
VFRLRTPAALAAAIGSRRAANQPAEARSAAPAPSPAAAVAAPVAPPAAPAPAQPREGAGGPAVGGTLATAAQRGIWLLEN
SPGGRAVSNAPLVFDYSGTLERARLARCVTHWLARHPILRSTYAWEDGALRIREREAAPFVLASVDLRAEPDEQRMVRAE
ALIAAEAMRPFDLRHDPMLRVTELRLGDHAGRLIFVFHHIAVDDRAMNVLFAELERDYRAGDAPLAVDAAPARRFADFAA
ETRGGTAAHADLAYWVEQLRDYRGATAYLVAPDAKPVARFAGRLHHHRLPAAISRDFEAAAARRAVTPFALFTTAVTALL
RHGAGTEDVTIGSFFSQRDHFADGELVGFFVNTLPLRVRSGADWDLDRLAQAVALTLADAQTHRHVAAEDIFDALQASTA
LRRAAFRVMVNLEPEQAETLEMDGFTARRVPLDRGVAKYDLLFSLRKEEGSYRVLVEYHTELYSETLIARICANLDRVLA
ALTGTARVALAALALPDPRDEAAWSAAPTDDGGAAAPADFRTLVREIWAGEVGHGDFGDGENFFDVGGSSLKIMSVYETL
SQRLAERGIDKELDIVALFEHVTVGTLADFLEEWTAHDALA

Specific function: Activates the 3rd to 6th amino acids (Ala, D-Leu, Ala and D-Val) in linear gramicidin and catalyzes the formation of the peptide bond between them. This enzyme is also responsible for the epimerization of the 4th (D-Leu) and the 6th (D-Val) amino acids [H

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=423, Percent_Identity=25.531914893617, Blast_Score=100, Evalue=7e-21,
Organism=Homo sapiens, GI38505220, Length=491, Percent_Identity=23.6252545824847, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI156151445, Length=358, Percent_Identity=22.6256983240223, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI42544132, Length=290, Percent_Identity=27.5862068965517, Blast_Score=78, Evalue=6e-14,
Organism=Homo sapiens, GI115511026, Length=193, Percent_Identity=29.0155440414508, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1786801, Length=597, Percent_Identity=32.6633165829146, Blast_Score=210, Evalue=5e-55,
Organism=Escherichia coli, GI1788107, Length=370, Percent_Identity=24.3243243243243, Blast_Score=81, Evalue=5e-16,
Organism=Escherichia coli, GI221142682, Length=517, Percent_Identity=23.7911025145068, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17550940, Length=426, Percent_Identity=25.8215962441315, Blast_Score=110, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17556356, Length=580, Percent_Identity=22.5862068965517, Blast_Score=97, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI32564422, Length=440, Percent_Identity=25.2272727272727, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI32564420, Length=440, Percent_Identity=25.2272727272727, Blast_Score=87, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560140, Length=391, Percent_Identity=24.0409207161125, Blast_Score=84, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17558820, Length=342, Percent_Identity=23.3918128654971, Blast_Score=80, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17560308, Length=375, Percent_Identity=23.7333333333333, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538037, Length=375, Percent_Identity=22.9333333333333, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17559526, Length=373, Percent_Identity=24.6648793565684, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17557194, Length=373, Percent_Identity=23.3243967828418, Blast_Score=75, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17531443, Length=370, Percent_Identity=21.8918918918919, Blast_Score=70, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6319591, Length=514, Percent_Identity=23.9299610894942, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319699, Length=371, Percent_Identity=25.3369272237197, Blast_Score=86, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24648676, Length=579, Percent_Identity=27.4611398963731, Blast_Score=145, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24648260, Length=365, Percent_Identity=24.3835616438356, Blast_Score=90, Evalue=9e-18,
Organism=Drosophila melanogaster, GI21355181, Length=368, Percent_Identity=26.0869565217391, Blast_Score=83, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356947, Length=355, Percent_Identity=25.9154929577465, Blast_Score=77, Evalue=7e-14,
Organism=Drosophila melanogaster, GI281365686, Length=184, Percent_Identity=28.2608695652174, Blast_Score=75, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653035, Length=188, Percent_Identity=30.8510638297872, Blast_Score=72, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21358303, Length=155, Percent_Identity=27.0967741935484, Blast_Score=68, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24581924, Length=365, Percent_Identity=25.4794520547945, Blast_Score=67, Evalue=6e-11,
Organism=Drosophila melanogaster, GI18859661, Length=339, Percent_Identity=23.8938053097345, Blast_Score=67, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR010060
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 124718; Mature: 124586

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSAPSVYAQFEQACAAQPDALALEGPSGQLSYAGLLASVAAIGTRLAEAGVTPGTLVG
CCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEE
VLLPRDFRLPAAILAAFGSQAVYVPLTEKYPPERIREIVLSHRITHVVTSQALTALLPPE
EECCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
CRAIVLPSEPGAAQGAGWRPAAPRGDDAPAYVVFTSGSTGTPKGVLIGEASLRNLIDWYR
CCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEHHHHHHHHHHHH
AAYRPDERRAVLASTQITFDLSLFELVCTLCSGSKVVLVDSILQLLEADAQFDVSLINTV
HHCCCCCCCEEEEEEEEEEEHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHHHHC
PSAARELVRRRRFPAATRVVNLAGEALYQDLVDAIHDAAPQVRQVYNLYGPSEDTTYSTG
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCC
HAVPRHGSSRTVSIGRSLPGKTAHLLDDALMPVEPGAVGEICLSGEGVALGYLNDPRLTE
CCCCCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCCCEEECCCCEEEEECCCCCCCH
QKFPTVAQGPLKGLRLYRTGDLGQFDDDGLLRYLGRADRQVKVRGVRIEPGEVEVALRGI
HHCCCCCCCCHHCEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCEEEEEHHH
AGVADAAVVKVVDPSGNDQLVALVVPQPGQVPGHEILDQLQSRLPAFMVPSRVEPIAAIP
CCCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEECCCCCCCEEEEE
LNGNGKTDRTALERIASACYRAEPAVDDLAEQVREVVATLMARTDVASDTDFFRIGGNSL
ECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHH
LSAQLTFLLQQRFAVTVSIADVFRLRTPAALAAAIGSRRAANQPAEARSAAPAPSPAAAV
HHHHHHHHHHHHHHEEEEHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHH
AAPVAPPAAPAPAQPREGAGGPAVGGTLATAAQRGIWLLENSPGGRAVSNAPLVFDYSGT
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCEECCCCEEEECCCC
LERARLARCVTHWLARHPILRSTYAWEDGALRIREREAAPFVLASVDLRAEPDEQRMVRA
HHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHH
EALIAAEAMRPFDLRHDPMLRVTELRLGDHAGRLIFVFHHIAVDDRAMNVLFAELERDYR
HHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEHHHHCHHHHHHHHHHHHHHHC
AGDAPLAVDAAPARRFADFAAETRGGTAAHADLAYWVEQLRDYRGATAYLVAPDAKPVAR
CCCCCEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
FAGRLHHHRLPAAISRDFEAAAARRAVTPFALFTTAVTALLRHGAGTEDVTIGSFFSQRD
HHHHHHHHCCCHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHCC
HFADGELVGFFVNTLPLRVRSGADWDLDRLAQAVALTLADAQTHRHVAAEDIFDALQAST
CCCCCCCCEEHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALRRAAFRVMVNLEPEQAETLEMDGFTARRVPLDRGVAKYDLLFSLRKEEGSYRVLVEYH
HHHHHHHHEEEECCCCCCCEEECCCCEEECCCHHCCCHHHHHHHHHHCCCCCEEEEEHHH
TELYSETLIARICANLDRVLAALTGTARVALAALALPDPRDEAAWSAAPTDDGGAAAPAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
FRTLVREIWAGEVGHGDFGDGENFFDVGGSSLKIMSVYETLSQRLAERGIDKELDIVALF
HHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHH
EHVTVGTLADFLEEWTAHDALA
HHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQSAPSVYAQFEQACAAQPDALALEGPSGQLSYAGLLASVAAIGTRLAEAGVTPGTLVG
CCCCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEE
VLLPRDFRLPAAILAAFGSQAVYVPLTEKYPPERIREIVLSHRITHVVTSQALTALLPPE
EECCCCCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
CRAIVLPSEPGAAQGAGWRPAAPRGDDAPAYVVFTSGSTGTPKGVLIGEASLRNLIDWYR
CCEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEHHHHHHHHHHHH
AAYRPDERRAVLASTQITFDLSLFELVCTLCSGSKVVLVDSILQLLEADAQFDVSLINTV
HHCCCCCCCEEEEEEEEEEEHHHHHHHHHHHCCCCEEHHHHHHHHHHCCCCCCHHHHHHC
PSAARELVRRRRFPAATRVVNLAGEALYQDLVDAIHDAAPQVRQVYNLYGPSEDTTYSTG
CHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCC
HAVPRHGSSRTVSIGRSLPGKTAHLLDDALMPVEPGAVGEICLSGEGVALGYLNDPRLTE
CCCCCCCCCCEEEECCCCCCCHHHHHHHCCCCCCCCCCCCEEECCCCEEEEECCCCCCCH
QKFPTVAQGPLKGLRLYRTGDLGQFDDDGLLRYLGRADRQVKVRGVRIEPGEVEVALRGI
HHCCCCCCCCHHCEEEEECCCCCCCCCCHHHHHHCCCCCEEEEEEEEECCCCEEEEEHHH
AGVADAAVVKVVDPSGNDQLVALVVPQPGQVPGHEILDQLQSRLPAFMVPSRVEPIAAIP
CCCCCCEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEECCCCCCCEEEEE
LNGNGKTDRTALERIASACYRAEPAVDDLAEQVREVVATLMARTDVASDTDFFRIGGNSL
ECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHH
LSAQLTFLLQQRFAVTVSIADVFRLRTPAALAAAIGSRRAANQPAEARSAAPAPSPAAAV
HHHHHHHHHHHHHHEEEEHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHCCCCCCCCHHHH
AAPVAPPAAPAPAQPREGAGGPAVGGTLATAAQRGIWLLENSPGGRAVSNAPLVFDYSGT
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEEECCCCCCEECCCCEEEECCCC
LERARLARCVTHWLARHPILRSTYAWEDGALRIREREAAPFVLASVDLRAEPDEQRMVRA
HHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEEEEECCCCCEEEEEEECCCCCCHHHHHHH
EALIAAEAMRPFDLRHDPMLRVTELRLGDHAGRLIFVFHHIAVDDRAMNVLFAELERDYR
HHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCEEEEEEHHHHCHHHHHHHHHHHHHHHC
AGDAPLAVDAAPARRFADFAAETRGGTAAHADLAYWVEQLRDYRGATAYLVAPDAKPVAR
CCCCCEEEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHH
FAGRLHHHRLPAAISRDFEAAAARRAVTPFALFTTAVTALLRHGAGTEDVTIGSFFSQRD
HHHHHHHHCCCHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEEHHHHHHCC
HFADGELVGFFVNTLPLRVRSGADWDLDRLAQAVALTLADAQTHRHVAAEDIFDALQAST
CCCCCCCCEEHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALRRAAFRVMVNLEPEQAETLEMDGFTARRVPLDRGVAKYDLLFSLRKEEGSYRVLVEYH
HHHHHHHHEEEECCCCCCCEEECCCCEEECCCHHCCCHHHHHHHHHHCCCCCEEEEEHHH
TELYSETLIARICANLDRVLAALTGTARVALAALALPDPRDEAAWSAAPTDDGGAAAPAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHH
FRTLVREIWAGEVGHGDFGDGENFFDVGGSSLKIMSVYETLSQRLAERGIDKELDIVALF
HHHHHHHHHCCCCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHHHHCCCCCCCHHHHHH
EHVTVGTLADFLEEWTAHDALA
HHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA