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The map label for this gene is atoC [H]

Identifier: 238028938

GI number: 238028938

Start: 3867336

End: 3868025

Strand: Reverse

Name: atoC [H]

Synonym: bglu_1g34030

Alternate gene names: 238028938

Gene position: 3868025-3867336 (Counterclockwise)

Preceding gene: 238028939

Following gene: 238028937

Centisome position: 99.01

GC content: 67.83

Gene sequence:

>690_bases
ATGGCAACCATCCTGGTGGTAGATGATGAAATGGGCATCCGGGAATTGCTCTCGGAAATCCTCGCCGACGAAGGACACGT
CGTCGAGGTGGCGGAAAACGCGCAGGCCGCGCGCGAGTATCGCCAGCGTCACGCGCCCGATCTCGTGCTGCTCGATATCT
GGATGCCCGATACCGACGGCGTCACGTTGTTGAAGGAGTGGGCGAGCCACGGACAACTGACGATGCCGGTGATCATGATG
TCGGGCCACGCGACGATCGACACGGCGGTCGAGGCGACCAAGATCGGCGCGCTCGATTTCCTCGAGAAGCCGATCGCGTT
GCAAAAGCTCCTGAAATCGGTCGAGCACGGGCTCGCGCGCGGCGCTGCGCCGGTGCCGCAGCACCCGGCCGTGAAGCCGG
CCGCCGGCCCGGCGCCCGTCGCCTCGGCGGCCGCGCTGCCGTCGATCGGCGAGGAAGCGGGCGCCGCGGCCGGGCTCGCG
GGCCAGGCCGCCGCGATTCCGTTCGACATCCCGCTGCGCGAGGCGCGCGACGCGTTCGAGCGCGCCTATTTCGAGTACCA
CCTCGCGCGCGAGAACGGCAGCATGACGCGCGTGGCGGAAAAGACCGGGCTCGAGCGCACGCACCTCTATCGCAAGCTCA
AGCAGCTCGGCGTCGAGCTCGGCAAGAAGACGTCCGAAGGCAGCGTTTGA

Upstream 100 bases:

>100_bases
CCTGCAACTCGCCGACGACACGACAGGCTCCGAGGGTGGAGCGGACAGCGCAACGGCACCCGCCAAGACAAAAGCAGCAG
TGCAGACAAGGGCAGCGTAA

Downstream 100 bases:

>100_bases
AATTTTTGCGGAAAAGGCTTGCCCTCGATGGGAGGGCTCGCTATAATCTCAATTCTTCGTTGGCCCGGTAGCTCAGTTGG
TAGAGCAGCGGATTGAAAAT

Product: Fis family two component transcriptional regulator

Products: NA

Alternate protein names: Ornithine decarboxylase antizyme; Ornithine/arginine decarboxylase inhibitor [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MATILVVDDEMGIRELLSEILADEGHVVEVAENAQAAREYRQRHAPDLVLLDIWMPDTDGVTLLKEWASHGQLTMPVIMM
SGHATIDTAVEATKIGALDFLEKPIALQKLLKSVEHGLARGAAPVPQHPAVKPAAGPAPVASAAALPSIGEEAGAAAGLA
GQAAAIPFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKTSEGSV

Sequences:

>Translated_229_residues
MATILVVDDEMGIRELLSEILADEGHVVEVAENAQAAREYRQRHAPDLVLLDIWMPDTDGVTLLKEWASHGQLTMPVIMM
SGHATIDTAVEATKIGALDFLEKPIALQKLLKSVEHGLARGAAPVPQHPAVKPAAGPAPVASAAALPSIGEEAGAAAGLA
GQAAAIPFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKTSEGSV
>Mature_228_residues
ATILVVDDEMGIRELLSEILADEGHVVEVAENAQAAREYRQRHAPDLVLLDIWMPDTDGVTLLKEWASHGQLTMPVIMMS
GHATIDTAVEATKIGALDFLEKPIALQKLLKSVEHGLARGAAPVPQHPAVKPAAGPAPVASAAALPSIGEEAGAAAGLAG
QAAAIPFDIPLREARDAFERAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKTSEGSV

Specific function: Member of the two-component regulatory system AtoS/AtoC involved in the transcriptional regulation of the ato genes for acetoacetate metabolism. Also an inhibitor of polyamine biosynthesis [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=42.6086956521739, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1790437, Length=128, Percent_Identity=36.71875, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI1787375, Length=130, Percent_Identity=28.4615384615385, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=36.2068965517241, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1786784, Length=122, Percent_Identity=33.6065573770492, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789809, Length=127, Percent_Identity=31.496062992126, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1786911, Length=135, Percent_Identity=31.8518518518519, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787229, Length=153, Percent_Identity=30.0653594771242, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788905, Length=121, Percent_Identity=35.5371900826446, Blast_Score=60, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 24509; Mature: 24378

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATILVVDDEMGIRELLSEILADEGHVVEVAENAQAAREYRQRHAPDLVLLDIWMPDTDG
CEEEEEECCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
VTLLKEWASHGQLTMPVIMMSGHATIDTAVEATKIGALDFLEKPIALQKLLKSVEHGLAR
HHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GAAPVPQHPAVKPAAGPAPVASAAALPSIGEEAGAAAGLAGQAAAIPFDIPLREARDAFE
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
RAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKTSEGSV
HHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ATILVVDDEMGIRELLSEILADEGHVVEVAENAQAAREYRQRHAPDLVLLDIWMPDTDG
EEEEEECCCCCHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
VTLLKEWASHGQLTMPVIMMSGHATIDTAVEATKIGALDFLEKPIALQKLLKSVEHGLAR
HHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
GAAPVPQHPAVKPAAGPAPVASAAALPSIGEEAGAAAGLAGQAAAIPFDIPLREARDAFE
CCCCCCCCCCCCCCCCCCCHHHHHHCCCCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHH
RAYFEYHLARENGSMTRVAEKTGLERTHLYRKLKQLGVELGKKTSEGSV
HHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 8346225 [H]