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The map label for this gene is mrdB [H]

Identifier: 238028933

GI number: 238028933

Start: 3862400

End: 3863548

Strand: Direct

Name: mrdB [H]

Synonym: bglu_1g33980

Alternate gene names: 238028933

Gene position: 3862400-3863548 (Clockwise)

Preceding gene: 238028932

Following gene: 238028946

Centisome position: 98.87

GC content: 65.45

Gene sequence:

>1149_bases
ATGCAATTCGACAAGCGCGCCTGGCTCGACAAGGCAAAGCAGATGTTCGCGGGCTTCGACCGCCCGCTCGCGCTGATCGT
GTTCCTGCTGCTCTGCGTGGGCATCGTCACGCTCTACAGCGCGAGCATCGACGTGCCCGGCCGCGTCGAGGACCAGCTTC
GCAACATCATGCTGACGTTCGTGCTGATGTGGATCATCGCGAATATCCCGCCGCAGACGCTGATGCGCTTCGCGGTGCCG
CTCTACTCGTTCGGCATCGCGCTGCTGGTGGCCGTCGCGCTGTTCGGGATGACCAAGAAGGGCGCGAAACGCTGGCTCAA
CATCGGCGTCGTGATCCAGCCGTCGGAAATCCTCAAGATCGCCACGCCGCTGATGCTCGCCTGGTACTACCAGCGCCGCG
AGGGCGGGATTCGCTGGTACGACTATCTGGTGGCGTTCGGCATCCTGCTGCTGCCGGTCGGGCTGATCGCCAAGCAGCCC
GACCTCGGCACCGCCGTGCTGGTGCTGGCAGCCGGCCTGTTCGTGATCTATCTGGCCGGGCTCTCGTTCAAGCTGATCGT
GCCGGTGCTCGTCGCCGGGGTGATCGCCGTGGTCGCGATCGCCACCTTCGAGGGCAAGATCTGCCAGCCCCAGGTGGTCT
GGCCGCTGATGCACGACTACCAGAAGCACCGCGTCTGCACCCTGCTCGATCCCACCACCGACCCGCTCGGCAAGGGCTTC
CACACGATCCAGGCGGTGATCGCGATCGGCTCGGGCGGCCCGTTCGGCAAGGGTTATCTGAAGGGCACGCAGGCCCACCT
CGAGTTCATCCCCGAGAAGCACACCGACTTCATCTTCGCGGTCTATTCCGAGGAATTCGGGCTCGTGGGCGGCCTGGTGC
TGCTCACGCTCTACATGGCGCTGATCACGCGCGGGCTGATCATCGCCGCGCAGGGCTCGACGCTGTTCGGACGATTGCTG
GCCGGCTCGCTCTCGCTCGGCTTCTTCACCTATGCGTTCGTCAACGTCGGGATGGTCAGCGGCGTGCTGCCGGTGGTGGG
CGTGCCGCTACCGTTCATGAGCTACGGCGGCACCGCGCTGATCACGCTCGGCGTGGCGACCGGCCTGATCATGAGCGTCG
CGCGGCAGAAGCGGCTGATGAAGTCGTAG

Upstream 100 bases:

>100_bases
ACCGCGCGCCCGCGAGCGCGGCGAGCGCCCCCGCCGCGACGCGCGACGAGCGCGTCCCCGCCCGGCCCGCCGCCGGCACC
GACGAATAACGGAGAAAGGC

Downstream 100 bases:

>100_bases
CGGTCCAGCCCCGCCCGGGTGGTCGGGCAGGATGCCCGCGTGAGCCGGCCTGTTTCATTGGCGAGGGCGGCGCGCGCTCA
CTGCGCGGCCGGCTGCGCGC

Product: Rod shape-determining protein RodA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MQFDKRAWLDKAKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDVPGRVEDQLRNIMLTFVLMWIIANIPPQTLMRFAVP
LYSFGIALLVAVALFGMTKKGAKRWLNIGVVIQPSEILKIATPLMLAWYYQRREGGIRWYDYLVAFGILLLPVGLIAKQP
DLGTAVLVLAAGLFVIYLAGLSFKLIVPVLVAGVIAVVAIATFEGKICQPQVVWPLMHDYQKHRVCTLLDPTTDPLGKGF
HTIQAVIAIGSGGPFGKGYLKGTQAHLEFIPEKHTDFIFAVYSEEFGLVGGLVLLTLYMALITRGLIIAAQGSTLFGRLL
AGSLSLGFFTYAFVNVGMVSGVLPVVGVPLPFMSYGGTALITLGVATGLIMSVARQKRLMKS

Sequences:

>Translated_382_residues
MQFDKRAWLDKAKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDVPGRVEDQLRNIMLTFVLMWIIANIPPQTLMRFAVP
LYSFGIALLVAVALFGMTKKGAKRWLNIGVVIQPSEILKIATPLMLAWYYQRREGGIRWYDYLVAFGILLLPVGLIAKQP
DLGTAVLVLAAGLFVIYLAGLSFKLIVPVLVAGVIAVVAIATFEGKICQPQVVWPLMHDYQKHRVCTLLDPTTDPLGKGF
HTIQAVIAIGSGGPFGKGYLKGTQAHLEFIPEKHTDFIFAVYSEEFGLVGGLVLLTLYMALITRGLIIAAQGSTLFGRLL
AGSLSLGFFTYAFVNVGMVSGVLPVVGVPLPFMSYGGTALITLGVATGLIMSVARQKRLMKS
>Mature_382_residues
MQFDKRAWLDKAKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDVPGRVEDQLRNIMLTFVLMWIIANIPPQTLMRFAVP
LYSFGIALLVAVALFGMTKKGAKRWLNIGVVIQPSEILKIATPLMLAWYYQRREGGIRWYDYLVAFGILLLPVGLIAKQP
DLGTAVLVLAAGLFVIYLAGLSFKLIVPVLVAGVIAVVAIATFEGKICQPQVVWPLMHDYQKHRVCTLLDPTTDPLGKGF
HTIQAVIAIGSGGPFGKGYLKGTQAHLEFIPEKHTDFIFAVYSEEFGLVGGLVLLTLYMALITRGLIIAAQGSTLFGRLL
AGSLSLGFFTYAFVNVGMVSGVLPVVGVPLPFMSYGGTALITLGVATGLIMSVARQKRLMKS

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=380, Percent_Identity=48.4210526315789, Blast_Score=291, Evalue=6e-80,
Organism=Escherichia coli, GI1786277, Length=387, Percent_Identity=30.2325581395349, Blast_Score=164, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41556; Mature: 41556

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFDKRAWLDKAKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDVPGRVEDQLRNIMLTF
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLMWIIANIPPQTLMRFAVPLYSFGIALLVAVALFGMTKKGAKRWLNIGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRREGGIRWYDYLVAFGILLLPVGLIAKQPDLGTAVLVLAAGLFVIYLAG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
LSFKLIVPVLVAGVIAVVAIATFEGKICQPQVVWPLMHDYQKHRVCTLLDPTTDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHCHH
HTIQAVIAIGSGGPFGKGYLKGTQAHLEFIPEKHTDFIFAVYSEEFGLVGGLVLLTLYMA
HHHHHHHHCCCCCCCCCCHHCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
LITRGLIIAAQGSTLFGRLLAGSLSLGFFTYAFVNVGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
ITLGVATGLIMSVARQKRLMKS
HHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFDKRAWLDKAKQMFAGFDRPLALIVFLLLCVGIVTLYSASIDVPGRVEDQLRNIMLTF
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
VLMWIIANIPPQTLMRFAVPLYSFGIALLVAVALFGMTKKGAKRWLNIGVVIQPSEILKI
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEECCHHHHHH
ATPLMLAWYYQRREGGIRWYDYLVAFGILLLPVGLIAKQPDLGTAVLVLAAGLFVIYLAG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHC
LSFKLIVPVLVAGVIAVVAIATFEGKICQPQVVWPLMHDYQKHRVCTLLDPTTDPLGKGF
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCEEEEECCCCCCHHCHH
HTIQAVIAIGSGGPFGKGYLKGTQAHLEFIPEKHTDFIFAVYSEEFGLVGGLVLLTLYMA
HHHHHHHHCCCCCCCCCCHHCCHHHHHHHCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
LITRGLIIAAQGSTLFGRLLAGSLSLGFFTYAFVNVGMVSGVLPVVGVPLPFMSYGGTAL
HHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCHHH
ITLGVATGLIMSVARQKRLMKS
HHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]