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The map label for this gene is yahK [H]

Identifier: 238028923

GI number: 238028923

Start: 3850444

End: 3851502

Strand: Direct

Name: yahK [H]

Synonym: bglu_1g33880

Alternate gene names: 238028923

Gene position: 3850444-3851502 (Clockwise)

Preceding gene: 238028921

Following gene: 238028929

Centisome position: 98.56

GC content: 67.33

Gene sequence:

>1059_bases
ATGAGCACGACTTACGCCTACGCGGCGCAGAGCGCAACCAGCCCGCTCGCGCCCATGCAGATCGAGCGCCGCGCGCTGCG
CGAGCTCGACGTCCAGATCGAAATCCTCTACTGCGGCGTCTGCCATTCCGACCTGCACCAGGCCCGCAACGAATGGCGCA
ATTCGATCTACCCGGTGGTGCCGGGCCACGAGATCGTCGGCCGCGTCACGGCCGTCGGCCCCGAGGTCAGCCGCTTCAAG
GCGGGCGACCTGGTCGGCGTCGGCTGCCTGGTCGATTCGTGCCGCACCTGCGCGAGCTGCTCGGAAGGCCTCGAGCAATA
CTGTGAAAACGGCTTCGTCGGCACCTACAACGGCCAGGACCGCGTGACGGGCGACATCACCTTCGGCGGCTACTCGTCGC
AGGTCGTCGTCGACGAGGCGTTCGTGCTGCGCGTGCCCGAGACGCTCGACCTCGCCGCCGCCGCGCCGCTGCTCTGCGCC
GGCATCACCACCTACTCGCCGCTGCGCCAGTGGGGCGCCGGCCCGGGCAAGAAGGTCGGCATCGTCGGCCTGGGCGGCCT
CGGCCACATGGGCGTGAAGCTCGCGCGCGCGATGGGCGCGCAGGTGGTGCTGTTCACCACCTCGCCGTCGAAGATCGAGG
ACGGCAAGCGGCTCGGCGCGCACGAAGTGGTGATCTCGAAGGACGAGGCGCAGATGAACGCGCACGCCAACAGCTTCGAT
CTGATCGTCAACACGGTGGCCGCGCAGCACGACCTGAACCCGTTCCTGAACCTGCTCAAGCGCGACGGCACGATGACGCT
GGTGGGCGCGCCCGAGCACGACCACCCGTCGCCGAACGTGTTCAACCTGATCTTCAAGCGCCGCCGCCTGGCCGGCTCGC
TGATCGGCGGCATCGCCGAGACGCAGGAGATGCTCGATTTCTGCGCCGAGCACGGCATCGTGTCGGACATCGAGCTGATC
AGGATCCAGGACATCAACCACGCGTATGAACGGATGCTCAAGAGCGACGTGAAGTACCGCTTCGTGATCGACATCGCTTC
GCTGAAGGACGCGGCGTAA

Upstream 100 bases:

>100_bases
GGCCACGCCCCCGTCCTTAGTATGGAAGCCCGTTTCGCGCCGCCGGCCGCTGCGGCGGGCGCGCGCGGATGTTTCGAATC
CCACGGTAAGGAGCCTCCCC

Downstream 100 bases:

>100_bases
GCGCGCCGCCCCGGCCGATGGCCGGGGCATCGGCAGGAAAAAAAACGCCGCCGGGAGTCATGCCGGCGGCGTTTTTTTGC
GACCTGGCGGGCGGCCGCTG

Product: Zn-dependent alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSTTYAYAAQSATSPLAPMQIERRALRELDVQIEILYCGVCHSDLHQARNEWRNSIYPVVPGHEIVGRVTAVGPEVSRFK
AGDLVGVGCLVDSCRTCASCSEGLEQYCENGFVGTYNGQDRVTGDITFGGYSSQVVVDEAFVLRVPETLDLAAAAPLLCA
GITTYSPLRQWGAGPGKKVGIVGLGGLGHMGVKLARAMGAQVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHANSFD
LIVNTVAAQHDLNPFLNLLKRDGTMTLVGAPEHDHPSPNVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGIVSDIELI
RIQDINHAYERMLKSDVKYRFVIDIASLKDAA

Sequences:

>Translated_352_residues
MSTTYAYAAQSATSPLAPMQIERRALRELDVQIEILYCGVCHSDLHQARNEWRNSIYPVVPGHEIVGRVTAVGPEVSRFK
AGDLVGVGCLVDSCRTCASCSEGLEQYCENGFVGTYNGQDRVTGDITFGGYSSQVVVDEAFVLRVPETLDLAAAAPLLCA
GITTYSPLRQWGAGPGKKVGIVGLGGLGHMGVKLARAMGAQVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHANSFD
LIVNTVAAQHDLNPFLNLLKRDGTMTLVGAPEHDHPSPNVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGIVSDIELI
RIQDINHAYERMLKSDVKYRFVIDIASLKDAA
>Mature_351_residues
STTYAYAAQSATSPLAPMQIERRALRELDVQIEILYCGVCHSDLHQARNEWRNSIYPVVPGHEIVGRVTAVGPEVSRFKA
GDLVGVGCLVDSCRTCASCSEGLEQYCENGFVGTYNGQDRVTGDITFGGYSSQVVVDEAFVLRVPETLDLAAAAPLLCAG
ITTYSPLRQWGAGPGKKVGIVGLGGLGHMGVKLARAMGAQVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHANSFDL
IVNTVAAQHDLNPFLNLLKRDGTMTLVGAPEHDHPSPNVFNLIFKRRRLAGSLIGGIAETQEMLDFCAEHGIVSDIELIR
IQDINHAYERMLKSDVKYRFVIDIASLKDAA

Specific function: Unknown

COG id: COG1064

COG function: function code R; Zn-dependent alcohol dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501933, Length=365, Percent_Identity=25.2054794520548, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI34577061, Length=364, Percent_Identity=24.7252747252747, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI71743840, Length=323, Percent_Identity=24.7678018575851, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI262073058, Length=323, Percent_Identity=24.7678018575851, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI4501929, Length=317, Percent_Identity=25.5520504731861, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI71565154, Length=242, Percent_Identity=27.6859504132231, Blast_Score=65, Evalue=1e-10,
Organism=Escherichia coli, GI1786518, Length=346, Percent_Identity=65.3179190751445, Blast_Score=426, Evalue=1e-120,
Organism=Escherichia coli, GI87082401, Length=345, Percent_Identity=35.6521739130435, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI87081918, Length=326, Percent_Identity=28.2208588957055, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI226510992, Length=243, Percent_Identity=30.4526748971193, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788073, Length=257, Percent_Identity=27.6264591439689, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790045, Length=275, Percent_Identity=26.5454545454545, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788407, Length=271, Percent_Identity=25.4612546125461, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI87082125, Length=223, Percent_Identity=25.1121076233184, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI71988145, Length=349, Percent_Identity=27.7936962750716, Blast_Score=148, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17562584, Length=359, Percent_Identity=29.2479108635098, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17562582, Length=352, Percent_Identity=28.6931818181818, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI25146526, Length=240, Percent_Identity=31.6666666666667, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71997431, Length=242, Percent_Identity=31.8181818181818, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17565904, Length=209, Percent_Identity=30.622009569378, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323980, Length=331, Percent_Identity=38.6706948640483, Blast_Score=187, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6319949, Length=336, Percent_Identity=36.9047619047619, Blast_Score=178, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6319621, Length=325, Percent_Identity=31.6923076923077, Blast_Score=157, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6323961, Length=325, Percent_Identity=33.5384615384615, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6324486, Length=325, Percent_Identity=32.3076923076923, Blast_Score=151, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6323729, Length=325, Percent_Identity=30.7692307692308, Blast_Score=148, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6319258, Length=311, Percent_Identity=26.3665594855305, Blast_Score=81, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6320033, Length=370, Percent_Identity=26.2162162162162, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319257, Length=301, Percent_Identity=24.5847176079734, Blast_Score=64, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17737895, Length=376, Percent_Identity=25.531914893617, Blast_Score=78, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR006140
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 38085; Mature: 37954

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00059 ADH_ZINC ; PS00065 D_2_HYDROXYACID_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTYAYAAQSATSPLAPMQIERRALRELDVQIEILYCGVCHSDLHQARNEWRNSIYPVV
CCCCCEEHHHCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCC
PGHEIVGRVTAVGPEVSRFKAGDLVGVGCLVDSCRTCASCSEGLEQYCENGFVGTYNGQD
CCHHHHHHHHHCCCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RVTGDITFGGYSSQVVVDEAFVLRVPETLDLAAAAPLLCAGITTYSPLRQWGAGPGKKVG
CEEEEEEECCCCCEEEEECEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEE
IVGLGGLGHMGVKLARAMGAQVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHANSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHCCCCHHH
LIVNTVAAQHDLNPFLNLLKRDGTMTLVGAPEHDHPSPNVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCAEHGIVSDIELIRIQDINHAYERMLKSDVKYRFVIDIASLKDAA
HHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
STTYAYAAQSATSPLAPMQIERRALRELDVQIEILYCGVCHSDLHQARNEWRNSIYPVV
CCCCEEHHHCCCCCCCHHHHHHHHHHHCCCEEEEEEEECCHHHHHHHHHHHHHCCCCCC
PGHEIVGRVTAVGPEVSRFKAGDLVGVGCLVDSCRTCASCSEGLEQYCENGFVGTYNGQD
CCHHHHHHHHHCCCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCC
RVTGDITFGGYSSQVVVDEAFVLRVPETLDLAAAAPLLCAGITTYSPLRQWGAGPGKKVG
CEEEEEEECCCCCEEEEECEEEEECCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEE
IVGLGGLGHMGVKLARAMGAQVVLFTTSPSKIEDGKRLGAHEVVISKDEAQMNAHANSFD
EEEECCCHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEEEECCHHHHHCCCCHHH
LIVNTVAAQHDLNPFLNLLKRDGTMTLVGAPEHDHPSPNVFNLIFKRRRLAGSLIGGIAE
HHHHHHHHHCCHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TQEMLDFCAEHGIVSDIELIRIQDINHAYERMLKSDVKYRFVIDIASLKDAA
HHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]