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The map label for this gene is glmU [H]

Identifier: 238028814

GI number: 238028814

Start: 3729518

End: 3730879

Strand: Direct

Name: glmU [H]

Synonym: bglu_1g32780

Alternate gene names: 238028814

Gene position: 3729518-3730879 (Clockwise)

Preceding gene: 238028813

Following gene: 238028815

Centisome position: 95.47

GC content: 71.29

Gene sequence:

>1362_bases
ATGAATATCGTGATTTTGGCGGCAGGCACCGGCAAGCGCATGCGATCCGCGCTGCCGAAGGTGCTCCATCCCCTGGCTGG
CAAGCCGCTCCTCTCCCACGTTCTCGATACCGCCCGCACGCTCGCGCCGTCGCGCCTGGTGGTGGTGGTCGGCCATGGCG
CGGAGGCCGTGCAGGCCGCCGTGGCCGCGCCCGACGTGCAGTTCGCGCTGCAGTCGCAGCAGCTGGGCACCGGCCACGCG
GTGCGGCAGGCACTGCCCTTGCTCGACCCGGCCCAGCCCACCCTGGTGCTGTACGGCGACGTGCCGCTCACGCGCGCCGG
CACGCTGCGGCGGCTCGTCGAGGCGGCCACCGACGCGCGCTACGGCATCCTCACCGTCACGCTCGACGATCCGACCGGCT
ATGGGCGCATCGTGCGCGACACCGCCGGCAGCGTCACGCGCATCGTCGAGCAGAAGGACGCCTCGCCCGAGCAGCTGCGC
ATCGCCGAGATCAACACCGGCATCATCGTCACGCCCACCGCCCAGCTCGCGATGTGGCTCGGCGCGCTCGGCAACGACAA
CGCCCAGGGCGAGTACTACCTGACCGACGTGGTCGAGCAGGCCATCGAGGCCGGCTTCGAGGTGGTGACGACCCAGCCCG
ACGAGGAATGGGAAACGCTCGGCGTCAACAGCAAGGCGCAGCTCGCCGAACTCGAGCGCATCCACCAGCGCAACCTGGCC
GAGGCGCTGCTGGCCGACGGCGTGACGCTCGCCGATCCGGCCCGCCTCGACATCCGCGGCTCGCTGGTGTGCGGGCGCGA
CGTGTCGATCGACGTGAACTGCGTGTTCGAGGGCGCCGTGGAGCTGGCCGACGGCGTGACGGTCGGCGCGAACTGCGTGA
TCCGCCATACCCGGATCGGCGCCGGCACGCGCATCGAGGCGTTCTCGCACCTGGAGGGCGCGCAGGTCGGCGCGCAGGCC
GTGGTCGGGCCGTATGCGCGGCTGCGGCCCGGCGCGGCGCTGGCCGACGAGGCGCACGTGGGCAACTTCGTCGAGGTGAA
GAACGCCGTGCTCGGGCACGGCGCGAAGGCCAACCACCTCACCTACCTCGGCGACGCCGACATCGGCGCGCGCGTCAACA
TCGGCGCCGGCACCATCACCTGCAACTACGACGGCGCGAACAAGTTCCGCACCGTGATCGAGGACGACGTGTTCGTCGGC
TCCGACACGCAGCTCGTCGCGCCGGTGCGCGTGGGCGCGGGCGCGACGATCGCGGCCGGCACCACGGTGTGGAAGGACGT
GGCGAGCGGCCAGCTCGTGCTCAACGACAAGCAGCAGACCGAGAAGGCCGGCTACGTGCGGCCCACCAAGAAGAAGAGCT
GA

Upstream 100 bases:

>100_bases
GGATGGGCGTTTCGCGGCACGGCGCGGCGCCGCCCGGCGCGATCGGCGCGCCCCCTGCGTGCTAGAATTCGGCACTTCGA
ACTCTCCCGACGCTGGCGCC

Downstream 100 bases:

>100_bases
ACGGTTCCGGCGGCTCAACACAGTTTCGGAAGGCGCACCTGGGTGGCGCCTTCCTCATTTCGGAGGATCGATCGCCATGT
GCGGCATTGTCGGCGCAGTT

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MNIVILAAGTGKRMRSALPKVLHPLAGKPLLSHVLDTARTLAPSRLVVVVGHGAEAVQAAVAAPDVQFALQSQQLGTGHA
VRQALPLLDPAQPTLVLYGDVPLTRAGTLRRLVEAATDARYGILTVTLDDPTGYGRIVRDTAGSVTRIVEQKDASPEQLR
IAEINTGIIVTPTAQLAMWLGALGNDNAQGEYYLTDVVEQAIEAGFEVVTTQPDEEWETLGVNSKAQLAELERIHQRNLA
EALLADGVTLADPARLDIRGSLVCGRDVSIDVNCVFEGAVELADGVTVGANCVIRHTRIGAGTRIEAFSHLEGAQVGAQA
VVGPYARLRPGAALADEAHVGNFVEVKNAVLGHGAKANHLTYLGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVG
SDTQLVAPVRVGAGATIAAGTTVWKDVASGQLVLNDKQQTEKAGYVRPTKKKS

Sequences:

>Translated_453_residues
MNIVILAAGTGKRMRSALPKVLHPLAGKPLLSHVLDTARTLAPSRLVVVVGHGAEAVQAAVAAPDVQFALQSQQLGTGHA
VRQALPLLDPAQPTLVLYGDVPLTRAGTLRRLVEAATDARYGILTVTLDDPTGYGRIVRDTAGSVTRIVEQKDASPEQLR
IAEINTGIIVTPTAQLAMWLGALGNDNAQGEYYLTDVVEQAIEAGFEVVTTQPDEEWETLGVNSKAQLAELERIHQRNLA
EALLADGVTLADPARLDIRGSLVCGRDVSIDVNCVFEGAVELADGVTVGANCVIRHTRIGAGTRIEAFSHLEGAQVGAQA
VVGPYARLRPGAALADEAHVGNFVEVKNAVLGHGAKANHLTYLGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVG
SDTQLVAPVRVGAGATIAAGTTVWKDVASGQLVLNDKQQTEKAGYVRPTKKKS
>Mature_453_residues
MNIVILAAGTGKRMRSALPKVLHPLAGKPLLSHVLDTARTLAPSRLVVVVGHGAEAVQAAVAAPDVQFALQSQQLGTGHA
VRQALPLLDPAQPTLVLYGDVPLTRAGTLRRLVEAATDARYGILTVTLDDPTGYGRIVRDTAGSVTRIVEQKDASPEQLR
IAEINTGIIVTPTAQLAMWLGALGNDNAQGEYYLTDVVEQAIEAGFEVVTTQPDEEWETLGVNSKAQLAELERIHQRNLA
EALLADGVTLADPARLDIRGSLVCGRDVSIDVNCVFEGAVELADGVTVGANCVIRHTRIGAGTRIEAFSHLEGAQVGAQA
VVGPYARLRPGAALADEAHVGNFVEVKNAVLGHGAKANHLTYLGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVG
SDTQLVAPVRVGAGATIAAGTTVWKDVASGQLVLNDKQQTEKAGYVRPTKKKS

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=452, Percent_Identity=54.8672566371681, Blast_Score=487, Evalue=1e-139,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 47632; Mature: 47632

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIVILAAGTGKRMRSALPKVLHPLAGKPLLSHVLDTARTLAPSRLVVVVGHGAEAVQAA
CEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
VAAPDVQFALQSQQLGTGHAVRQALPLLDPAQPTLVLYGDVPLTRAGTLRRLVEAATDAR
HCCCCHHEEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCC
YGILTVTLDDPTGYGRIVRDTAGSVTRIVEQKDASPEQLRIAEINTGIIVTPTAQLAMWL
EEEEEEEECCCCCCCEEEECCCCHHHHHHHHCCCCHHHEEEEEECCCEEECCHHHHHHHH
GALGNDNAQGEYYLTDVVEQAIEAGFEVVTTQPDEEWETLGVNSKAQLAELERIHQRNLA
HHCCCCCCCCCEEHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
EALLADGVTLADPARLDIRGSLVCGRDVSIDVNCVFEGAVELADGVTVGANCVIRHTRIG
HHHHHCCCEECCCCEEEEEEEEEECCCCEEEEEEEEECHHHHHCCEEECCEEEEEEEECC
AGTRIEAFSHLEGAQVGAQAVVGPYARLRPGAALADEAHVGNFVEVKNAVLGHGAKANHL
CCCEEHHHHHCCCHHCCCHHHHCCHHHCCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCE
TYLGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVGSDTQLVAPVRVGAGATIAAG
EEECCCCCCCEEEECCEEEEEECCCCHHHHHHHCCCEEECCCCEEEEEEEECCCCEEECC
TTVWKDVASGQLVLNDKQQTEKAGYVRPTKKKS
CHHHHHHCCCEEEECCCHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MNIVILAAGTGKRMRSALPKVLHPLAGKPLLSHVLDTARTLAPSRLVVVVGHGAEAVQAA
CEEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHH
VAAPDVQFALQSQQLGTGHAVRQALPLLDPAQPTLVLYGDVPLTRAGTLRRLVEAATDAR
HCCCCHHEEECCCCCCCHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHCCCC
YGILTVTLDDPTGYGRIVRDTAGSVTRIVEQKDASPEQLRIAEINTGIIVTPTAQLAMWL
EEEEEEEECCCCCCCEEEECCCCHHHHHHHHCCCCHHHEEEEEECCCEEECCHHHHHHHH
GALGNDNAQGEYYLTDVVEQAIEAGFEVVTTQPDEEWETLGVNSKAQLAELERIHQRNLA
HHCCCCCCCCCEEHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCHHHHHHHHHHHHHHHH
EALLADGVTLADPARLDIRGSLVCGRDVSIDVNCVFEGAVELADGVTVGANCVIRHTRIG
HHHHHCCCEECCCCEEEEEEEEEECCCCEEEEEEEEECHHHHHCCEEECCEEEEEEEECC
AGTRIEAFSHLEGAQVGAQAVVGPYARLRPGAALADEAHVGNFVEVKNAVLGHGAKANHL
CCCEEHHHHHCCCHHCCCHHHHCCHHHCCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCE
TYLGDADIGARVNIGAGTITCNYDGANKFRTVIEDDVFVGSDTQLVAPVRVGAGATIAAG
EEECCCCCCCEEEECCEEEEEECCCCHHHHHHHCCCEEECCCCEEEEEEEECCCCEEECC
TTVWKDVASGQLVLNDKQQTEKAGYVRPTKKKS
CHHHHHHCCCEEEECCCHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA