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The map label for this gene is glmS [H]

Identifier: 238028815

GI number: 238028815

Start: 3730956

End: 3732773

Strand: Direct

Name: glmS [H]

Synonym: bglu_1g32790

Alternate gene names: 238028815

Gene position: 3730956-3732773 (Clockwise)

Preceding gene: 238028814

Following gene: 238028816

Centisome position: 95.51

GC content: 68.98

Gene sequence:

>1818_bases
ATGTGCGGCATTGTCGGCGCAGTTGCGCAACGTAACATCGTTCCGGTGCTGATCGAAGGTCTGCGCCGGCTGGAATACCG
CGGGTACGACTCGTGCGGAGTGGCCGTGCTCGAGGGCGGCGAGCCCAGGCGCGCGCGCAGCGTCTCGCGCGTGGCCGACC
TCGACGCGCAGGTGCGCGAGACCGGCCTCGAGGGCATGACCGGCATCTCGCATACGCGCTGGGCCACGCACGGCGCGCCC
GTCACGCACAACGCGCATCCGATCTTCTCGCGCGACACGGTCGCGCTGGTTCACAACGGCATCATCGAGAACTACGAGAC
GCTGCGCGAGACGCTGCGCGCGAAGGGCTACGAGTTCGTGTCGCAGACCGACACCGAGGTGATCGCGCATCTCGTGCACA
GCCTCTATCGCGGCGACCTGTTCGCCGCCGTGCGCGAGGCCGTCGCGCAGCTGCACGGCGCCTATGCGATCGCCGTGATC
CACAAGGACCAGCCCAACACCGTGGTGGGCGCGCGGCAGGGCTCGCCGCTGGTGGTCGGCTTCGGCGACGGCGAGAACTT
CCTGGCCTCCGACGCGCTGGCGCTGGCCGGCAGCACCGACCGCTTCACGTTCCTCGAGGAAGGCGACGTCTGCGAGCTGT
CGCTCGACAGCGTGAAGATCGTCGACCGCAGCGGCGCGCACGTGGAGCGCGAGGTGCGCACCGTAAGCGCCTACGGCGGC
GCCGTCGAACTCGGCCCGTACCGCCACTTCATGCAGAAGGAAATCTTCGAGCAGCCGCGCGCGATCGCCGACACCATCCC
GCCCATCGAAGCGTTCGAGGCCGCACTGTTCGGCGCGGGCGCGGCCGAGACCTTCGCCGACATCGACAGCCTGCTGATCC
TCGCCTGCGGCACCAGCTACTACTCGGGCATGACCGCCAAGTACTGGCTCGAATCGATCGCGAAGATCCCCACCCAGGTG
GAGATCGCCAGCGAGTACCGCTACCGCGACTCGGTGCCGAACCCGCGCGCGCTGGTGGTGGTGATCTCGCAGTCGGGCGA
GACCGCCGACACGCTCGCCGCGCTCAAGCACGCGCAGTCGCTGGGCCACCAGCGCACGCTGGCCGTCTGCAACGTGGCGA
CCAGCGCGATGGTGCGCCAGACCGGGCTGCAGTTCCTGACGCGCGCCGGCACCGAGATCGGCGTGGCCTCGACCAAGGCG
TTCACCACCCAGCTGGTGGCGCTGTTCCTGCTCGCGGCCACGCTCGGCAAGGTGCGCGGGCACGTGGACGCGGCCCGCGA
GGCCGACTACATCCGTCAGCTGCGCCACCTGCCGGCCGCGCTGAACAGCGTGCTGGCGCTGGAGCCGCAGATCATCGCCT
GGTCGGAGGAGTTCTCGCGCAAGGAGAACGCGCTGTTCCTCGGCCGCGGGCTGCACTACCCGATCGCGCTGGAAGGCGCA
CTGAAGCTCAAGGAGATTTCGTATATCCACGCGGAAGCCTATCCGGCCGGCGAGCTGAAGCACGGGCCGCTCGCGCTGGT
GACGGAGGCGATGCCGGTGGTGACGGTGGCGCCGAACGACACGCTGCTGGAGAAGCTGAAGTCGAACATGCAGGAAGTGC
GCGCGCGCGGCGGCGAGCTGTACGTGTTCGCCGACGCCGACACGCACATCGTCAACGACGAGGGGCTGCATGTGATCCGG
ATGCCGGAGCACTACGGCGCGCTGTCGCCGATCCTGCACGTGGTGCCGCTGCAGCTGCTGGCGTATCACACCGCTTGCGC
GCGAGGCACGGACGTGGACAAGCCGCGGAATCTGGCGAAGTCGGTGACGGTGGAGTGA

Upstream 100 bases:

>100_bases
CGGCCCACCAAGAAGAAGAGCTGAACGGTTCCGGCGGCTCAACACAGTTTCGGAAGGCGCACCTGGGTGGCGCCTTCCTC
ATTTCGGAGGATCGATCGCC

Downstream 100 bases:

>100_bases
GGGCGGCGGGGCGGGAGCCCCGTCGCGTCGCAACGCCCCGCGCAGCCGATGCGGGAGGCGCTCATGCCGGCCCTTCATGC
CGGCCGCTCGTGCCGGTCCC

Product: glucosamine--fructose-6-phosphate aminotransferase

Products: NA

Alternate protein names: D-fructose-6-phosphate amidotransferase; GFAT; Glucosamine-6-phosphate synthase; Hexosephosphate aminotransferase; L-glutamine-D-fructose-6-phosphate amidotransferase [H]

Number of amino acids: Translated: 605; Mature: 605

Protein sequence:

>605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEGGEPRRARSVSRVADLDAQVRETGLEGMTGISHTRWATHGAP
VTHNAHPIFSRDTVALVHNGIIENYETLRETLRAKGYEFVSQTDTEVIAHLVHSLYRGDLFAAVREAVAQLHGAYAIAVI
HKDQPNTVVGARQGSPLVVGFGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDSVKIVDRSGAHVEREVRTVSAYGG
AVELGPYRHFMQKEIFEQPRAIADTIPPIEAFEAALFGAGAAETFADIDSLLILACGTSYYSGMTAKYWLESIAKIPTQV
EIASEYRYRDSVPNPRALVVVISQSGETADTLAALKHAQSLGHQRTLAVCNVATSAMVRQTGLQFLTRAGTEIGVASTKA
FTTQLVALFLLAATLGKVRGHVDAAREADYIRQLRHLPAALNSVLALEPQIIAWSEEFSRKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTHIVNDEGLHVIR
MPEHYGALSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Sequences:

>Translated_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEGGEPRRARSVSRVADLDAQVRETGLEGMTGISHTRWATHGAP
VTHNAHPIFSRDTVALVHNGIIENYETLRETLRAKGYEFVSQTDTEVIAHLVHSLYRGDLFAAVREAVAQLHGAYAIAVI
HKDQPNTVVGARQGSPLVVGFGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDSVKIVDRSGAHVEREVRTVSAYGG
AVELGPYRHFMQKEIFEQPRAIADTIPPIEAFEAALFGAGAAETFADIDSLLILACGTSYYSGMTAKYWLESIAKIPTQV
EIASEYRYRDSVPNPRALVVVISQSGETADTLAALKHAQSLGHQRTLAVCNVATSAMVRQTGLQFLTRAGTEIGVASTKA
FTTQLVALFLLAATLGKVRGHVDAAREADYIRQLRHLPAALNSVLALEPQIIAWSEEFSRKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTHIVNDEGLHVIR
MPEHYGALSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE
>Mature_605_residues
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEGGEPRRARSVSRVADLDAQVRETGLEGMTGISHTRWATHGAP
VTHNAHPIFSRDTVALVHNGIIENYETLRETLRAKGYEFVSQTDTEVIAHLVHSLYRGDLFAAVREAVAQLHGAYAIAVI
HKDQPNTVVGARQGSPLVVGFGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDSVKIVDRSGAHVEREVRTVSAYGG
AVELGPYRHFMQKEIFEQPRAIADTIPPIEAFEAALFGAGAAETFADIDSLLILACGTSYYSGMTAKYWLESIAKIPTQV
EIASEYRYRDSVPNPRALVVVISQSGETADTLAALKHAQSLGHQRTLAVCNVATSAMVRQTGLQFLTRAGTEIGVASTKA
FTTQLVALFLLAATLGKVRGHVDAAREADYIRQLRHLPAALNSVLALEPQIIAWSEEFSRKENALFLGRGLHYPIALEGA
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGELYVFADADTHIVNDEGLHVIR
MPEHYGALSPILHVVPLQLLAYHTACARGTDVDKPRNLAKSVTVE

Specific function: Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source [H]

COG id: COG0449

COG function: function code M; Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 SIS domains [H]

Homologues:

Organism=Homo sapiens, GI205277386, Length=687, Percent_Identity=36.098981077147, Blast_Score=384, Evalue=1e-106,
Organism=Homo sapiens, GI4826742, Length=685, Percent_Identity=36.2043795620438, Blast_Score=384, Evalue=1e-106,
Organism=Escherichia coli, GI1790167, Length=611, Percent_Identity=55.9738134206219, Blast_Score=660, Evalue=0.0,
Organism=Escherichia coli, GI1788651, Length=233, Percent_Identity=27.8969957081545, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17539970, Length=430, Percent_Identity=39.3023255813954, Blast_Score=281, Evalue=7e-76,
Organism=Caenorhabditis elegans, GI17532899, Length=430, Percent_Identity=38.1395348837209, Blast_Score=278, Evalue=7e-75,
Organism=Caenorhabditis elegans, GI17532897, Length=430, Percent_Identity=38.1395348837209, Blast_Score=277, Evalue=9e-75,
Organism=Saccharomyces cerevisiae, GI6322745, Length=449, Percent_Identity=36.7483296213808, Blast_Score=266, Evalue=5e-72,
Organism=Saccharomyces cerevisiae, GI6323731, Length=432, Percent_Identity=28.9351851851852, Blast_Score=187, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6323730, Length=205, Percent_Identity=34.6341463414634, Blast_Score=110, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6323958, Length=290, Percent_Identity=25.1724137931034, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357745, Length=685, Percent_Identity=35.9124087591241, Blast_Score=378, Evalue=1e-105,
Organism=Drosophila melanogaster, GI28573187, Length=256, Percent_Identity=28.125, Blast_Score=74, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000583
- InterPro:   IPR017932
- InterPro:   IPR005855
- InterPro:   IPR001347 [H]

Pfam domain/function: PF00310 GATase_2; PF01380 SIS [H]

EC number: =2.6.1.16 [H]

Molecular weight: Translated: 65590; Mature: 65590

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEGGEPRRARSVSRVADLDAQVRE
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
TGLEGMTGISHTRWATHGAPVTHNAHPIFSRDTVALVHNGIIENYETLRETLRAKGYEFV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SQTDTEVIAHLVHSLYRGDLFAAVREAVAQLHGAYAIAVIHKDQPNTVVGARQGSPLVVG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEECCCCCEEEEE
FGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDSVKIVDRSGAHVEREVRTVSAYGG
ECCCCCHHHHHHHHCCCCCCCEEEECCCCEEEEECCCEEEECCCCCHHHHHHHHHHHCCC
AVELGPYRHFMQKEIFEQPRAIADTIPPIEAFEAALFGAGAAETFADIDSLLILACGTSY
EEEECHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHH
YSGMTAKYWLESIAKIPTQVEIASEYRYRDSVPNPRALVVVISQSGETADTLAALKHAQS
HCCCCHHHHHHHHHHCCCEEEHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHQRTLAVCNVATSAMVRQTGLQFLTRAGTEIGVASTKAFTTQLVALFLLAATLGKVRG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HVDAAREADYIRQLRHLPAALNSVLALEPQIIAWSEEFSRKENALFLGRGLHYPIALEGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCEEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGEL
EEHHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTHIVNDEGLHVIRMPEHYGALSPILHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
SVTVE
HCCCC
>Mature Secondary Structure
MCGIVGAVAQRNIVPVLIEGLRRLEYRGYDSCGVAVLEGGEPRRARSVSRVADLDAQVRE
CCCCHHHHHHCCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHH
TGLEGMTGISHTRWATHGAPVTHNAHPIFSRDTVALVHNGIIENYETLRETLRAKGYEFV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHH
SQTDTEVIAHLVHSLYRGDLFAAVREAVAQLHGAYAIAVIHKDQPNTVVGARQGSPLVVG
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEECCCCCEEEEE
FGDGENFLASDALALAGSTDRFTFLEEGDVCELSLDSVKIVDRSGAHVEREVRTVSAYGG
ECCCCCHHHHHHHHCCCCCCCEEEECCCCEEEEECCCEEEECCCCCHHHHHHHHHHHCCC
AVELGPYRHFMQKEIFEQPRAIADTIPPIEAFEAALFGAGAAETFADIDSLLILACGTSY
EEEECHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHH
YSGMTAKYWLESIAKIPTQVEIASEYRYRDSVPNPRALVVVISQSGETADTLAALKHAQS
HCCCCHHHHHHHHHHCCCEEEHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHH
LGHQRTLAVCNVATSAMVRQTGLQFLTRAGTEIGVASTKAFTTQLVALFLLAATLGKVRG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
HVDAAREADYIRQLRHLPAALNSVLALEPQIIAWSEEFSRKENALFLGRGLHYPIALEGA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHCCCCCEEEEECCCCCCEEECCC
LKLKEISYIHAEAYPAGELKHGPLALVTEAMPVVTVAPNDTLLEKLKSNMQEVRARGGEL
EEHHHHHEEEECCCCCCCCCCCCHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCEE
YVFADADTHIVNDEGLHVIRMPEHYGALSPILHVVPLQLLAYHTACARGTDVDKPRNLAK
EEEECCCCEEECCCCEEEEECCHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHH
SVTVE
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]