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The map label for this gene is csgA [H]

Identifier: 238028776

GI number: 238028776

Start: 3680532

End: 3681209

Strand: Direct

Name: csgA [H]

Synonym: bglu_1g32400

Alternate gene names: 238028776

Gene position: 3680532-3681209 (Clockwise)

Preceding gene: 238028775

Following gene: 238028777

Centisome position: 94.22

GC content: 73.3

Gene sequence:

>678_bases
ATGAAAACCGTCCTGATCGTCGGCGCGTCGCGCGGCCTGGGCAGGGAGTTTGTCCGCCAGTACCGGCGTGACGGATGGAA
CGTGATCGCCACCGCGCGCGACGCGGCCTCGCTGGCGGCGCTGCGCGCGCTCGGCGCGACCGCGCACGCGCTCGACGTGA
CCGATGCCAACCAGCTGGCCGGCTTCGGCTGGAAGCTCGACGGCGAGCGGCTGGACGCCGCGGTGCTGGTGTCGGGCGTG
TACGGCCCGCGCACGCAGGGCGTCGAGCTGATCGACGCGGCCGACTTCGACACGGTGATGCACACCAACGTGCTGGCCCC
GATGCAGCTGCTGCCGATCCTGCTGCCGCTGGTCGAGGACGCGCAAGGCGTGCTGGCCGTGCTGTCGAGCCTGATGGGCA
GCACCGCCGGCCTGACCGGCACCACCGGCTGGCTGTACCGCGCGAGCAAGGCCGCGCTCAACAACGTGATCCGCGTGGCG
TCGCTGCAAACGCGCGCGGCGGCCTGCCTGTCGCTGCACCCGGGCTGGGTGCGCACCGACATGGGCGGCGCCGAAGCCGG
GCTCGACGCCGAGACCAGCGTGACCGGCATGCGCCGCGTGATCGCGCGCGCCGCCGCCGGGCCGGGCGCCGCCAACGGCC
GCTTCTTCCAATACGACGGCACCGAGCTCGCGTGGTAG

Upstream 100 bases:

>100_bases
GGCGGCAAGCGCGGCATGGCGAGCCTCTGCATCGGCGGCGGCGAGGCCACGGCGCTGGCCGTCGAACTGTACTGATCGGC
CTCGACCCGGAGACTCATCG

Downstream 100 bases:

>100_bases
TCAGGATGACCGATCGTTGTTCCGCTCCCCCTGCCGCCCCCTGCGCCGCGCCGGCCGCGCGCCCCGAGCTGTGCCCGTGC
GGCGGCGCGCAGCCGGGCCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDAASLAALRALGATAHALDVTDANQLAGFGWKLDGERLDAAVLVSGV
YGPRTQGVELIDAADFDTVMHTNVLAPMQLLPILLPLVEDAQGVLAVLSSLMGSTAGLTGTTGWLYRASKAALNNVIRVA
SLQTRAAACLSLHPGWVRTDMGGAEAGLDAETSVTGMRRVIARAAAGPGAANGRFFQYDGTELAW

Sequences:

>Translated_225_residues
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDAASLAALRALGATAHALDVTDANQLAGFGWKLDGERLDAAVLVSGV
YGPRTQGVELIDAADFDTVMHTNVLAPMQLLPILLPLVEDAQGVLAVLSSLMGSTAGLTGTTGWLYRASKAALNNVIRVA
SLQTRAAACLSLHPGWVRTDMGGAEAGLDAETSVTGMRRVIARAAAGPGAANGRFFQYDGTELAW
>Mature_225_residues
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDAASLAALRALGATAHALDVTDANQLAGFGWKLDGERLDAAVLVSGV
YGPRTQGVELIDAADFDTVMHTNVLAPMQLLPILLPLVEDAQGVLAVLSSLMGSTAGLTGTTGWLYRASKAALNNVIRVA
SLQTRAAACLSLHPGWVRTDMGGAEAGLDAETSVTGMRRVIARAAAGPGAANGRFFQYDGTELAW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Caenorhabditis elegans, GI17558994, Length=250, Percent_Identity=28.8, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17558990, Length=250, Percent_Identity=28.8, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24640547, Length=252, Percent_Identity=29.3650793650794, Blast_Score=96, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23590; Mature: 23590

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDAASLAALRALGATAHALDVTDANQLA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCCHHEEECCCCHHHC
GFGWKLDGERLDAAVLVSGVYGPRTQGVELIDAADFDTVMHTNVLAPMQLLPILLPLVED
CCCEEECCCHHCHHHEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
AQGVLAVLSSLMGSTAGLTGTTGWLYRASKAALNNVIRVASLQTRAAACLSLHPGWVRTD
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
MGGAEAGLDAETSVTGMRRVIARAAAGPGAANGRFFQYDGTELAW
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MKTVLIVGASRGLGREFVRQYRRDGWNVIATARDAASLAALRALGATAHALDVTDANQLA
CCEEEEEECCCCCCHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCCHHEEECCCCHHHC
GFGWKLDGERLDAAVLVSGVYGPRTQGVELIDAADFDTVMHTNVLAPMQLLPILLPLVED
CCCEEECCCHHCHHHEEECCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHC
AQGVLAVLSSLMGSTAGLTGTTGWLYRASKAALNNVIRVASLQTRAAACLSLHPGWVRTD
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEC
MGGAEAGLDAETSVTGMRRVIARAAAGPGAANGRFFQYDGTELAW
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]