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The map label for this gene is ybhO [H]

Identifier: 238028610

GI number: 238028610

Start: 3495123

End: 3496397

Strand: Reverse

Name: ybhO [H]

Synonym: bglu_1g30740

Alternate gene names: 238028610

Gene position: 3496397-3495123 (Counterclockwise)

Preceding gene: 238028611

Following gene: 238028609

Centisome position: 89.5

GC content: 71.14

Gene sequence:

>1275_bases
ATGAGCGGCGGCAAGCGGCTGCGCCTCACCCAGTTGCGGGACCTGTTCCTGCAGGAGCGCGGGTCGTCGTCGCGGCTCGC
GTTCAGCGCCGGCAACACCGTCACGCTGCGCCACGGCGGCGCCGAGTTCTTTCCGGCGCTGGTGCGCCGCATCGACGAGG
CCTCGGTGTCGGTGCTGCTGGAAACCTACATCTTCTGCGACGACGCGGCCGGCCGCCTGGTGTCCGACGCGCTGCTGCGC
GCGGCCGGGCGCGGCGTGCACGTGCGCGTGATCACCGACGGCATCGGCACCGCGCGCCTGCCGCTGTTCGAGCGCTGGCA
GGCGGCCGGCATCGAGCACCGCATCTACAACCGCTACCTGTTCGGCCGCCTCGGCTTTTCGCGCACGCACCGCAAGCTCG
CCTGCGTCGACGACGCCTACGCGTTCTGCGGCGGCATCAACATCGTGGACGATTACGAGCAGAACGGCGAGCGCCTGCCG
TTCCCGCGCTGGGATTTCGCCGTCGAGCTGGCCGGGCCGGCCGCGGCCGACGTGCGCGCGGCGTTCGAGGTGCAGTGGTA
TCGCGTGCGGATGGGCCACAAGCGCTATGCGCAGTACGTGCCGCCGACGGTGACGAGCGAGGCGTTCGCCGCGCGCTTCC
GGCGCTGGGTGCGCAATCATCGCTGGGTCAAGGTGGGCGCGCTGCGCAACGTGACCGAACCGAGCGTGGCGTTCGTCGCG
CGCGACAACGTGCTGAACCGGCGCGCGATCGAGAAGGCCTACCTGGCCGCGATCGGCCGCGCGCGCCAGGCGGTGGTGCT
GGCCAATCCGTACTTCATGCCGGGGCGCAAGCTGCGCCGCGCGCTGACCAACGCGGCGCGGCGCGGCGTCGAGGTGCGCG
TGCTGATCGGCCGCAAGGAATTCGTCGCGCTCGATACGGCCGTGCCGTTCCTTTATCATGCGTTGCTGCGCGCCGGGGTG
CGGGTGGCCGAGTACGACCGGACCATGCTGCACGGCAAGGTGGCGGTGGTCGACGACAGCTGGGCGACCGTCGGCTCGTC
GAACCTCGACGCCCTGAGCCTGATGCTCAATAACGAGGCGAACGTGGTGCTGGTGCGGCACGACGCCGAGATCGCCGCGC
TGCGCGAGGCGATCGACGCGGCCTTCGCGGACGGCCGCGAGATCGACGCGGCCCGCTACGCGGCGCGCCCGCCGCTGGAG
CGGCTGATGAACTGGCTCGCCTACACCGCGTACCGCTGGTCGATGAAACTGCTGACGGTGGGCGGCTACGACTAG

Upstream 100 bases:

>100_bases
ATCTCTGGCTGCCGTACCGCGAGGCGGCCGCGCGCTGCTACTCGCCGTCCAACGCCGAGGCGATCCTTCAGCTTCCCGCG
CGCCTCGCGGCGCGTGAGGC

Downstream 100 bases:

>100_bases
CCCGCGCCGGCCGGAACCGGCCGCAGGCCCGTTCGTTGCGAGCCCCGGGGGCGCGCCGGAATGCCGCGCGCAGGGCTGGT
CAACCCTTGCCGTGCCGGCC

Product: putative phospholipase

Products: cardiolipin; glycerol [C]

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSGGKRLRLTQLRDLFLQERGSSSRLAFSAGNTVTLRHGGAEFFPALVRRIDEASVSVLLETYIFCDDAAGRLVSDALLR
AAGRGVHVRVITDGIGTARLPLFERWQAAGIEHRIYNRYLFGRLGFSRTHRKLACVDDAYAFCGGINIVDDYEQNGERLP
FPRWDFAVELAGPAAADVRAAFEVQWYRVRMGHKRYAQYVPPTVTSEAFAARFRRWVRNHRWVKVGALRNVTEPSVAFVA
RDNVLNRRAIEKAYLAAIGRARQAVVLANPYFMPGRKLRRALTNAARRGVEVRVLIGRKEFVALDTAVPFLYHALLRAGV
RVAEYDRTMLHGKVAVVDDSWATVGSSNLDALSLMLNNEANVVLVRHDAEIAALREAIDAAFADGREIDAARYAARPPLE
RLMNWLAYTAYRWSMKLLTVGGYD

Sequences:

>Translated_424_residues
MSGGKRLRLTQLRDLFLQERGSSSRLAFSAGNTVTLRHGGAEFFPALVRRIDEASVSVLLETYIFCDDAAGRLVSDALLR
AAGRGVHVRVITDGIGTARLPLFERWQAAGIEHRIYNRYLFGRLGFSRTHRKLACVDDAYAFCGGINIVDDYEQNGERLP
FPRWDFAVELAGPAAADVRAAFEVQWYRVRMGHKRYAQYVPPTVTSEAFAARFRRWVRNHRWVKVGALRNVTEPSVAFVA
RDNVLNRRAIEKAYLAAIGRARQAVVLANPYFMPGRKLRRALTNAARRGVEVRVLIGRKEFVALDTAVPFLYHALLRAGV
RVAEYDRTMLHGKVAVVDDSWATVGSSNLDALSLMLNNEANVVLVRHDAEIAALREAIDAAFADGREIDAARYAARPPLE
RLMNWLAYTAYRWSMKLLTVGGYD
>Mature_423_residues
SGGKRLRLTQLRDLFLQERGSSSRLAFSAGNTVTLRHGGAEFFPALVRRIDEASVSVLLETYIFCDDAAGRLVSDALLRA
AGRGVHVRVITDGIGTARLPLFERWQAAGIEHRIYNRYLFGRLGFSRTHRKLACVDDAYAFCGGINIVDDYEQNGERLPF
PRWDFAVELAGPAAADVRAAFEVQWYRVRMGHKRYAQYVPPTVTSEAFAARFRRWVRNHRWVKVGALRNVTEPSVAFVAR
DNVLNRRAIEKAYLAAIGRARQAVVLANPYFMPGRKLRRALTNAARRGVEVRVLIGRKEFVALDTAVPFLYHALLRAGVR
VAEYDRTMLHGKVAVVDDSWATVGSSNLDALSLMLNNEANVVLVRHDAEIAALREAIDAAFADGREIDAARYAARPPLER
LMNWLAYTAYRWSMKLLTVGGYD

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=381, Percent_Identity=36.745406824147, Blast_Score=195, Evalue=5e-51,
Organism=Escherichia coli, GI1787502, Length=391, Percent_Identity=26.8542199488491, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI87081826, Length=408, Percent_Identity=27.9411764705882, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.- [C]

Molecular weight: Translated: 47583; Mature: 47452

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGGKRLRLTQLRDLFLQERGSSSRLAFSAGNTVTLRHGGAEFFPALVRRIDEASVSVLL
CCCCCEEHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
ETYIFCDDAAGRLVSDALLRAAGRGVHVRVITDGIGTARLPLFERWQAAGIEHRIYNRYL
HHHHEECCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHH
FGRLGFSRTHRKLACVDDAYAFCGGINIVDDYEQNGERLPFPRWDFAVELAGPAAADVRA
HHHCCCCCCCCEEEEHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHH
AFEVQWYRVRMGHKRYAQYVPPTVTSEAFAARFRRWVRNHRWVKVGALRNVTEPSVAFVA
HHEEEEEEEHHCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEE
RDNVLNRRAIEKAYLAAIGRARQAVVLANPYFMPGRKLRRALTNAARRGVEVRVLIGRKE
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCC
FVALDTAVPFLYHALLRAGVRVAEYDRTMLHGKVAVVDDSWATVGSSNLDALSLMLNNEA
EEEHHHHHHHHHHHHHHCCCEEHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEEECCCC
NVVLVRHDAEIAALREAIDAAFADGREIDAARYAARPPLERLMNWLAYTAYRWSMKLLTV
CEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHEEEEEEEEE
GGYD
CCCC
>Mature Secondary Structure 
SGGKRLRLTQLRDLFLQERGSSSRLAFSAGNTVTLRHGGAEFFPALVRRIDEASVSVLL
CCCCEEHHHHHHHHHHHCCCCCCEEEEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHH
ETYIFCDDAAGRLVSDALLRAAGRGVHVRVITDGIGTARLPLFERWQAAGIEHRIYNRYL
HHHHEECCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHCCCHHHHHHHHH
FGRLGFSRTHRKLACVDDAYAFCGGINIVDDYEQNGERLPFPRWDFAVELAGPAAADVRA
HHHCCCCCCCCEEEEHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEECCCCHHHHHH
AFEVQWYRVRMGHKRYAQYVPPTVTSEAFAARFRRWVRNHRWVKVGALRNVTEPSVAFVA
HHEEEEEEEHHCHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEE
RDNVLNRRAIEKAYLAAIGRARQAVVLANPYFMPGRKLRRALTNAARRGVEVRVLIGRKE
CCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEECCCC
FVALDTAVPFLYHALLRAGVRVAEYDRTMLHGKVAVVDDSWATVGSSNLDALSLMLNNEA
EEEHHHHHHHHHHHHHHCCCEEHHHHHHHHCCEEEEEECCCCCCCCCCCCEEEEEECCCC
NVVLVRHDAEIAALREAIDAAFADGREIDAARYAARPPLERLMNWLAYTAYRWSMKLLTV
CEEEEECCCHHHHHHHHHHHHHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHEEEEEEEEE
GGYD
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 L-1-phosphatidyl-glycerol [C]

Specific reaction: 2 L-1-phosphatidyl-glycerol = cardiolipin + glycerol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]