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The map label for this gene is yhdN [H]

Identifier: 238028553

GI number: 238028553

Start: 3424168

End: 3425160

Strand: Direct

Name: yhdN [H]

Synonym: bglu_1g30170

Alternate gene names: 238028553

Gene position: 3424168-3425160 (Clockwise)

Preceding gene: 238028552

Following gene: 238028555

Centisome position: 87.65

GC content: 71.9

Gene sequence:

>993_bases
ATGAACATCGAAACCACCCGCATCGCGGGCATCGACACGCCGGTGTCGCGCATCGGCCTGGGCACCTGGGCGATCGGCGG
CTGGATGTGGGGCGGCACCGACGACCGGCAGTCGATCGCCACCGTGCGCCAGGCCGTCGAGCAGGGCATCAACCTGATCG
ACACGGCGCCCGTCTACGGCTTCGGCCATGCCGAGTCGATCGTCGGCGAGGCGCTCGCGGGCATCCGCGACCAGGCCGTG
ATCGCCACCAAGGTCGCGCTCGAGTGGAACGCCGACGAGCAGGTCATGCGCAATGCCAGCGTCGCGCGGATCCGCCGCGA
GATCGAGGATTCGCTGCGCCGGCTGCGCACCGACCGCATCGACCTCTATCAGGTCCACTGGCCCGACCCGCTGGTGCCGT
TCGAGGAGACCGCCGCCGAACTCGAACGCCTGCGCCGCGACGGCAAGATCCTCGCGATCGGCGTGAGCAACTACAGCCCG
GCGCAGATGGAGCGATTCGCCTCGGCCGCGCCGCTGGCCACCGTGCAGCCGCCTTACAACTTGTTCGAGCGCGCGATCGA
GGCCGACGTGCTGCCGTATGCGCAGCAGCATGGGCTGCAGGTGCTGGCCTACGGCGCGCTGTGCCGCGGCCTGCTGTCGG
GGCGGATGACGGCCGACACGCGCTTCCAGGGCGACGACCTGCGCCGCACCGATCCGAAGTTCCAGGCGCCGCGCTTCGCG
CAATACCTGGCGGCGGTGGACGCGCTGGCGGGCCTCGCCCGCGAGCGGCACGGCAAATCGGTGCTGGCGCTCGCGATCCG
CTGGGTGCTGGACCAGGGGCCGACCATCGCGCTGTGGGGCGCGCGCAGGCCGGAGCAGCTGAGCGGCATCGGCGACGCGT
TCGGCTGGCGGCTCGACGCGCGCGATCTGGCCGACATCGACGCGCTCCTGGCGCGGCACGTGACCGACCCGGTCGGGCCG
GAATTCATGGCGCCGCCGCTGCGCACGGCCTGA

Upstream 100 bases:

>100_bases
CCCATCGTGCCGGCCTGCCGCCGCAACGGCGCGGCAAGCGCGCGCAGCGCATTGATCGCCGGTCTAGACTGGCGCTTTCA
ACCCGCCAAGCGAGATCAGC

Downstream 100 bases:

>100_bases
GCCGCACGACCAGGGCCGCGCCGCCCAAATCGCAGGGCCGCGGAGCCGGCCGCCGCGCACAGCATTTATCCAAGCGCCGC
GGTGGACAAGTGCTGTGCGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: GSP69; AKR11B [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNIETTRIAGIDTPVSRIGLGTWAIGGWMWGGTDDRQSIATVRQAVEQGINLIDTAPVYGFGHAESIVGEALAGIRDQAV
IATKVALEWNADEQVMRNASVARIRREIEDSLRRLRTDRIDLYQVHWPDPLVPFEETAAELERLRRDGKILAIGVSNYSP
AQMERFASAAPLATVQPPYNLFERAIEADVLPYAQQHGLQVLAYGALCRGLLSGRMTADTRFQGDDLRRTDPKFQAPRFA
QYLAAVDALAGLARERHGKSVLALAIRWVLDQGPTIALWGARRPEQLSGIGDAFGWRLDARDLADIDALLARHVTDPVGP
EFMAPPLRTA

Sequences:

>Translated_330_residues
MNIETTRIAGIDTPVSRIGLGTWAIGGWMWGGTDDRQSIATVRQAVEQGINLIDTAPVYGFGHAESIVGEALAGIRDQAV
IATKVALEWNADEQVMRNASVARIRREIEDSLRRLRTDRIDLYQVHWPDPLVPFEETAAELERLRRDGKILAIGVSNYSP
AQMERFASAAPLATVQPPYNLFERAIEADVLPYAQQHGLQVLAYGALCRGLLSGRMTADTRFQGDDLRRTDPKFQAPRFA
QYLAAVDALAGLARERHGKSVLALAIRWVLDQGPTIALWGARRPEQLSGIGDAFGWRLDARDLADIDALLARHVTDPVGP
EFMAPPLRTA
>Mature_330_residues
MNIETTRIAGIDTPVSRIGLGTWAIGGWMWGGTDDRQSIATVRQAVEQGINLIDTAPVYGFGHAESIVGEALAGIRDQAV
IATKVALEWNADEQVMRNASVARIRREIEDSLRRLRTDRIDLYQVHWPDPLVPFEETAAELERLRRDGKILAIGVSNYSP
AQMERFASAAPLATVQPPYNLFERAIEADVLPYAQQHGLQVLAYGALCRGLLSGRMTADTRFQGDDLRRTDPKFQAPRFA
QYLAAVDALAGLARERHGKSVLALAIRWVLDQGPTIALWGARRPEQLSGIGDAFGWRLDARDLADIDALLARHVTDPVGP
EFMAPPLRTA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=288, Percent_Identity=28.125, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI4504825, Length=288, Percent_Identity=28.125, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI223718702, Length=214, Percent_Identity=28.5046728971963, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436962, Length=288, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436966, Length=288, Percent_Identity=27.7777777777778, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI27436964, Length=288, Percent_Identity=27.7777777777778, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI41327764, Length=272, Percent_Identity=30.8823529411765, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI41152114, Length=194, Percent_Identity=29.8969072164948, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI27436971, Length=295, Percent_Identity=27.7966101694915, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI223718708, Length=126, Percent_Identity=32.5396825396825, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1788070, Length=321, Percent_Identity=36.7601246105919, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1788081, Length=208, Percent_Identity=39.4230769230769, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789199, Length=345, Percent_Identity=32.463768115942, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081735, Length=323, Percent_Identity=31.2693498452012, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=28.8753799392097, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI48994888, Length=264, Percent_Identity=29.1666666666667, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87082198, Length=297, Percent_Identity=25.5892255892256, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1786400, Length=204, Percent_Identity=32.843137254902, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787674, Length=183, Percent_Identity=29.5081967213115, Blast_Score=72, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI212645785, Length=220, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323998, Length=333, Percent_Identity=27.9279279279279, Blast_Score=99, Evalue=8e-22,
Organism=Saccharomyces cerevisiae, GI6319958, Length=307, Percent_Identity=27.0358306188925, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=246, Percent_Identity=30.0813008130081, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6322615, Length=260, Percent_Identity=26.5384615384615, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325169, Length=310, Percent_Identity=23.8709677419355, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24646155, Length=209, Percent_Identity=34.4497607655502, Blast_Score=92, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24646159, Length=221, Percent_Identity=31.2217194570136, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24640980, Length=311, Percent_Identity=27.6527331189711, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI45549126, Length=311, Percent_Identity=27.6527331189711, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR018170
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36367; Mature: 36367

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIETTRIAGIDTPVSRIGLGTWAIGGWMWGGTDDRQSIATVRQAVEQGINLIDTAPVYG
CCCCCEEECCCCCCHHHHCCCHHHHCCEECCCCCCHHHHHHHHHHHHHCCCEEECCCCCC
FGHAESIVGEALAGIRDQAVIATKVALEWNADEQVMRNASVARIRREIEDSLRRLRTDRI
CCHHHHHHHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DLYQVHWPDPLVPFEETAAELERLRRDGKILAIGVSNYSPAQMERFASAAPLATVQPPYN
EEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHH
LFERAIEADVLPYAQQHGLQVLAYGALCRGLLSGRMTADTRFQGDDLRRTDPKFQAPRFA
HHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHH
QYLAAVDALAGLARERHGKSVLALAIRWVLDQGPTIALWGARRPEQLSGIGDAFGWRLDA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCHHHHCCCCCC
RDLADIDALLARHVTDPVGPEFMAPPLRTA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIETTRIAGIDTPVSRIGLGTWAIGGWMWGGTDDRQSIATVRQAVEQGINLIDTAPVYG
CCCCCEEECCCCCCHHHHCCCHHHHCCEECCCCCCHHHHHHHHHHHHHCCCEEECCCCCC
FGHAESIVGEALAGIRDQAVIATKVALEWNADEQVMRNASVARIRREIEDSLRRLRTDRI
CCHHHHHHHHHHHCCCCCCEEEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
DLYQVHWPDPLVPFEETAAELERLRRDGKILAIGVSNYSPAQMERFASAAPLATVQPPYN
EEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHCCCCCCCCCCHH
LFERAIEADVLPYAQQHGLQVLAYGALCRGLLSGRMTADTRFQGDDLRRTDPKFQAPRFA
HHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHH
QYLAAVDALAGLARERHGKSVLALAIRWVLDQGPTIALWGARRPEQLSGIGDAFGWRLDA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCHHHHCCCCCC
RDLADIDALLARHVTDPVGPEFMAPPLRTA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 9298659 [H]