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The map label for this gene is cbbA [H]

Identifier: 238028512

GI number: 238028512

Start: 3370058

End: 3371122

Strand: Reverse

Name: cbbA [H]

Synonym: bglu_1g29760

Alternate gene names: 238028512

Gene position: 3371122-3370058 (Counterclockwise)

Preceding gene: 238028513

Following gene: 238028511

Centisome position: 86.3

GC content: 65.63

Gene sequence:

>1065_bases
ATGCCTCTCGTATCAATGCGTCAACTGCTGGATCACGCGGCAGAGCATGGCTATGGCCTGCCGGCATTCAACGTGAACAA
CCTGGAGCAGGTGCAGGCGATCATGGCGGCGGCCGACCAGGTCGGCGCGCCGGTGATCATGCAGGCGTCGGCCGGCGCCC
GGAAGTACGCAGGCGAGGCGTTCCTGCGCCATCTGATCGAATCGGCGGTCGAGTCGTATCCGCACATTCCGGTCGTGATG
CACCAGGATCACGGCCAGTCGCCGGCGGTCTGCCTCGCGGCGATCCGCAGCGGCTTCTCGAGCGTGATGATGGACGGCTC
GCTGGAGGCCGACGGCAAGTCGGTGGCGTCGTATGAATACAACGTCGACGTGTCGCGCAAGGTCGTCGAGATGGCCCACG
CGATCGGCGTGACGGTGGAGGCCGAACTCGGCGTGCTCGGTTCGCTCGAGACCATGAAGGGCGACAAGGAAGACGGCCAC
GGCGCCGACGGCACCATGACGCGCGAGCAGCTGCTGACGGACCCCGAGCAGGCCGCCGACTTCGTCAGGGAGACGCAGTG
CGACGCGCTGGCGATCGCGATCGGCACCTCGCATGGCGCCTACAAGTTCTCGAAGAAGCCCACCGGCGATATCCTCTCGA
TCGAGCGGATCAAGGAGATCCACGCGCGCATCCCGAACACGCACCTCGTGATGCACGGTTCGTCGTCGGTGCCGCAGGAA
CTGCTGGCCGAGATCCGCGAGTTCGGCGGCGACATGAAGGAAACCTACGGCGTGCCGGTCGAGGAAATCCAGGAAGGCAT
CAAGCACGGCGTGCGCAAGATCAACATCGATACCGACCTGCGTCTGGCGATCACGGGCGCGATCCGTCGCTACCTGTTCG
AGAACCCGTCGAAGTTCGATCCGCGCGACTATCTGAAGCCGGCCCGCGAGGCCGCCAAGCAGGTCTGCGTGGCGCGCTAC
CTCGCGTTCGGCTGCGAAGGCCAGGCCGCGAAGATCAAGCCGGTGCCGCTCGACAAGATGGCCGAGCGCTACAAGGCGGG
CGAACTGGCCCAGCTCGTGCGCTAA

Upstream 100 bases:

>100_bases
TCGACGCTCGGCCGCGCCGCGCCCGCCCCGTGTTCTCGTCCGGAGCCGGCATGTCGCCGCCGCCCAAAGCGCACCGGTTT
TCATTAGACGGAGTACCACA

Downstream 100 bases:

>100_bases
CATAGCTGCCGCGGCCGCCCGGTGCGCCGGGCGGCTGTCGGCCGGAGGCCTCGCCGCCGTTCCCGCCTGTCGAAGGGGAA
CGGCGTTTCCCTTTTGTTTG

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MPLVSMRQLLDHAAEHGYGLPAFNVNNLEQVQAIMAAADQVGAPVIMQASAGARKYAGEAFLRHLIESAVESYPHIPVVM
HQDHGQSPAVCLAAIRSGFSSVMMDGSLEADGKSVASYEYNVDVSRKVVEMAHAIGVTVEAELGVLGSLETMKGDKEDGH
GADGTMTREQLLTDPEQAADFVRETQCDALAIAIGTSHGAYKFSKKPTGDILSIERIKEIHARIPNTHLVMHGSSSVPQE
LLAEIREFGGDMKETYGVPVEEIQEGIKHGVRKINIDTDLRLAITGAIRRYLFENPSKFDPRDYLKPAREAAKQVCVARY
LAFGCEGQAAKIKPVPLDKMAERYKAGELAQLVR

Sequences:

>Translated_354_residues
MPLVSMRQLLDHAAEHGYGLPAFNVNNLEQVQAIMAAADQVGAPVIMQASAGARKYAGEAFLRHLIESAVESYPHIPVVM
HQDHGQSPAVCLAAIRSGFSSVMMDGSLEADGKSVASYEYNVDVSRKVVEMAHAIGVTVEAELGVLGSLETMKGDKEDGH
GADGTMTREQLLTDPEQAADFVRETQCDALAIAIGTSHGAYKFSKKPTGDILSIERIKEIHARIPNTHLVMHGSSSVPQE
LLAEIREFGGDMKETYGVPVEEIQEGIKHGVRKINIDTDLRLAITGAIRRYLFENPSKFDPRDYLKPAREAAKQVCVARY
LAFGCEGQAAKIKPVPLDKMAERYKAGELAQLVR
>Mature_353_residues
PLVSMRQLLDHAAEHGYGLPAFNVNNLEQVQAIMAAADQVGAPVIMQASAGARKYAGEAFLRHLIESAVESYPHIPVVMH
QDHGQSPAVCLAAIRSGFSSVMMDGSLEADGKSVASYEYNVDVSRKVVEMAHAIGVTVEAELGVLGSLETMKGDKEDGHG
ADGTMTREQLLTDPEQAADFVRETQCDALAIAIGTSHGAYKFSKKPTGDILSIERIKEIHARIPNTHLVMHGSSSVPQEL
LAEIREFGGDMKETYGVPVEEIQEGIKHGVRKINIDTDLRLAITGAIRRYLFENPSKFDPRDYLKPAREAAKQVCVARYL
AFGCEGQAAKIKPVPLDKMAERYKAGELAQLVR

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=34.9544072948328, Blast_Score=174, Evalue=5e-45,
Organism=Escherichia coli, GI1789526, Length=316, Percent_Identity=32.9113924050633, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1788072, Length=328, Percent_Identity=28.9634146341463, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1789293, Length=358, Percent_Identity=24.3016759776536, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322790, Length=364, Percent_Identity=26.9230769230769, Blast_Score=82, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38520; Mature: 38389

Theoretical pI: Translated: 6.06; Mature: 6.06

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLVSMRQLLDHAAEHGYGLPAFNVNNLEQVQAIMAAADQVGAPVIMQASAGARKYAGEA
CCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
FLRHLIESAVESYPHIPVVMHQDHGQSPAVCLAAIRSGFSSVMMDGSLEADGKSVASYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
NVDVSRKVVEMAHAIGVTVEAELGVLGSLETMKGDKEDGHGADGTMTREQLLTDPEQAAD
CCCHHHHHHHHHHHHCCEEEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHH
FVRETQCDALAIAIGTSHGAYKFSKKPTGDILSIERIKEIHARIPNTHLVMHGSSSVPQE
HHHHHCCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
LLAEIREFGGDMKETYGVPVEEIQEGIKHGVRKINIDTDLRLAITGAIRRYLFENPSKFD
HHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCCCCC
PRDYLKPAREAAKQVCVARYLAFGCEGQAAKIKPVPLDKMAERYKAGELAQLVR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHC
>Mature Secondary Structure 
PLVSMRQLLDHAAEHGYGLPAFNVNNLEQVQAIMAAADQVGAPVIMQASAGARKYAGEA
CHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHH
FLRHLIESAVESYPHIPVVMHQDHGQSPAVCLAAIRSGFSSVMMDGSLEADGKSVASYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEE
NVDVSRKVVEMAHAIGVTVEAELGVLGSLETMKGDKEDGHGADGTMTREQLLTDPEQAAD
CCCHHHHHHHHHHHHCCEEEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHH
FVRETQCDALAIAIGTSHGAYKFSKKPTGDILSIERIKEIHARIPNTHLVMHGSSSVPQE
HHHHHCCCEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
LLAEIREFGGDMKETYGVPVEEIQEGIKHGVRKINIDTDLRLAITGAIRRYLFENPSKFD
HHHHHHHHCCCHHHHCCCCHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHCCCCCCC
PRDYLKPAREAAKQVCVARYLAFGCEGQAAKIKPVPLDKMAERYKAGELAQLVR
CHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550527 [H]