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The map label for this gene is purC [H]

Identifier: 238028511

GI number: 238028511

Start: 3369043

End: 3369933

Strand: Reverse

Name: purC [H]

Synonym: bglu_1g29750

Alternate gene names: 238028511

Gene position: 3369933-3369043 (Counterclockwise)

Preceding gene: 238028512

Following gene: 238028510

Centisome position: 86.26

GC content: 67.68

Gene sequence:

>891_bases
ATGTCTACCCTTTACGAATCCACGCTCCGTTCGCTGCCGCTCCTCGGTCGCGGCAAGGTCCGCGACAACTACGCGGTCGG
CACCGACAAGCTCCTGATCGTGACGAGCGACCGGCTCTCGGCGTTCGACGTGGTGATGGGCGAGCCGATTCCGAACAAGG
GGCGCGTGCTGAACCAGATGGCCAATTTCTGGTTCGAGAAGCTCTCGCACATCGTGCCGAACCACCTCACCGGCGACGCG
CCGGAGGCGGTGGTGGCGGCCGACGAGGTCGAGCAGGTGAAGGGCCGCGCGGTGGTGGTCAAGCGCCTCGAGCCGATCCT
CGTCGAGGCGGTGGTGCGCGGCTATCTGGCCGGCAGCGGCTGGAAGGACTACCAGGCCACCGGCGCGGTGTGCGGCGTCG
AGCTGCCGCCGGGCCTGCAGAACGCGCAGAAGCTGCCCGAACCGATCTTCACGCCGGCCGCCAAGGCCGAGCTGGGCCAC
CACGACGAAAACATCAGCTACGACGAATGCGAGCGCCGCATCGGCACCGAGCTGACCGCCACGATCCGCGACATCTCGAT
CCGCCTCTACCAGGAAGCGGCCGACTACGCGGCCACCCGCGGCATCATCATCGCCGACACCAAGTTCGAGTTCGGCCTCG
ACCAGCACGGCAAGCTCTACCTGATGGACGAGGCGCTGACGGCCGATTCGTCGCGCTTCTGGCCGGCCGACCAGTACCAG
GTCGGCACCAACCCGCCGTCGTTCGACAAGCAGTACGTGCGCGACTGGCTCGAAACCCAGGACTGGCCGAAGGCGCCGCC
CGCGCCGAAGCTGCCCGACGAAGTGATCGCGCGCACCAGCGCGAAGTATCAGGAAGCGCTCGAGCGCATCACGGGCCGCC
CGCTCGTCTGA

Upstream 100 bases:

>100_bases
CGCCGGGCGGCTGTCGGCCGGAGGCCTCGCCGCCGTTCCCGCCTGTCGAAGGGGAACGGCGTTTCCCTTTTGTTTGGCTC
ACATTTTCTTCGATACGACG

Downstream 100 bases:

>100_bases
GCGCGCCGCCCCCCGCGGATAACGAAGGAAACGCCGTACATGAGTGAAGTCCAGACCGCCCACACGCACAGCGCGCCGCT
CGTCGGCGTGCTGATGGGCT

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MSTLYESTLRSLPLLGRGKVRDNYAVGTDKLLIVTSDRLSAFDVVMGEPIPNKGRVLNQMANFWFEKLSHIVPNHLTGDA
PEAVVAADEVEQVKGRAVVVKRLEPILVEAVVRGYLAGSGWKDYQATGAVCGVELPPGLQNAQKLPEPIFTPAAKAELGH
HDENISYDECERRIGTELTATIRDISIRLYQEAADYAATRGIIIADTKFEFGLDQHGKLYLMDEALTADSSRFWPADQYQ
VGTNPPSFDKQYVRDWLETQDWPKAPPAPKLPDEVIARTSAKYQEALERITGRPLV

Sequences:

>Translated_296_residues
MSTLYESTLRSLPLLGRGKVRDNYAVGTDKLLIVTSDRLSAFDVVMGEPIPNKGRVLNQMANFWFEKLSHIVPNHLTGDA
PEAVVAADEVEQVKGRAVVVKRLEPILVEAVVRGYLAGSGWKDYQATGAVCGVELPPGLQNAQKLPEPIFTPAAKAELGH
HDENISYDECERRIGTELTATIRDISIRLYQEAADYAATRGIIIADTKFEFGLDQHGKLYLMDEALTADSSRFWPADQYQ
VGTNPPSFDKQYVRDWLETQDWPKAPPAPKLPDEVIARTSAKYQEALERITGRPLV
>Mature_295_residues
STLYESTLRSLPLLGRGKVRDNYAVGTDKLLIVTSDRLSAFDVVMGEPIPNKGRVLNQMANFWFEKLSHIVPNHLTGDAP
EAVVAADEVEQVKGRAVVVKRLEPILVEAVVRGYLAGSGWKDYQATGAVCGVELPPGLQNAQKLPEPIFTPAAKAELGHH
DENISYDECERRIGTELTATIRDISIRLYQEAADYAATRGIIIADTKFEFGLDQHGKLYLMDEALTADSSRFWPADQYQV
GTNPPSFDKQYVRDWLETQDWPKAPPAPKLPDEVIARTSAKYQEALERITGRPLV

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=291, Percent_Identity=45.0171821305842, Blast_Score=259, Evalue=3e-70,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 32878; Mature: 32746

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS01057 SAICAR_SYNTHETASE_1 ; PS01058 SAICAR_SYNTHETASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLYESTLRSLPLLGRGKVRDNYAVGTDKLLIVTSDRLSAFDVVMGEPIPNKGRVLNQM
CCHHHHHHHHHCCCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHCCCCCCHHHHHHHH
ANFWFEKLSHIVPNHLTGDAPEAVVAADEVEQVKGRAVVVKRLEPILVEAVVRGYLAGSG
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
WKDYQATGAVCGVELPPGLQNAQKLPEPIFTPAAKAELGHHDENISYDECERRIGTELTA
CCCHHCCCCEEECCCCCCCHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHCCHHHH
TIRDISIRLYQEAADYAATRGIIIADTKFEFGLDQHGKLYLMDEALTADSSRFWPADQYQ
HHHHHHHHHHHHHHHHHHHCCEEEECCCEECCCCCCCCEEEEECHHCCCCCCCCCCCCEE
VGTNPPSFDKQYVRDWLETQDWPKAPPAPKLPDEVIARTSAKYQEALERITGRPLV
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
STLYESTLRSLPLLGRGKVRDNYAVGTDKLLIVTSDRLSAFDVVMGEPIPNKGRVLNQM
CHHHHHHHHHCCCCCCCCCCCCEEECCCEEEEEECCCCCHHHHHHCCCCCCHHHHHHHH
ANFWFEKLSHIVPNHLTGDAPEAVVAADEVEQVKGRAVVVKRLEPILVEAVVRGYLAGSG
HHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCC
WKDYQATGAVCGVELPPGLQNAQKLPEPIFTPAAKAELGHHDENISYDECERRIGTELTA
CCCHHCCCCEEECCCCCCCHHHHHCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHCCHHHH
TIRDISIRLYQEAADYAATRGIIIADTKFEFGLDQHGKLYLMDEALTADSSRFWPADQYQ
HHHHHHHHHHHHHHHHHHHCCEEEECCCEECCCCCCCCEEEEECHHCCCCCCCCCCCCEE
VGTNPPSFDKQYVRDWLETQDWPKAPPAPKLPDEVIARTSAKYQEALERITGRPLV
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA