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The map label for this gene is lrp [H]

Identifier: 238028473

GI number: 238028473

Start: 3324937

End: 3325437

Strand: Reverse

Name: lrp [H]

Synonym: bglu_1g29370

Alternate gene names: 238028473

Gene position: 3325437-3324937 (Counterclockwise)

Preceding gene: 339905978

Following gene: 238028471

Centisome position: 85.13

GC content: 63.47

Gene sequence:

>501_bases
ATGCACGCAATCTCGCTGGATGCTACCGATTGCCGTATTCTCGCCGTATTGCAGCAAGAGGGCCGGATCAGCAACCTCGA
TCTGGCCGAACGTATTTCGCTGTCGCCGTCGGCCTGCTTGAGGCGCATGCGCCTGCTCGAGGAGCAGGGCGTGATCGAGT
GCTATCGCGCCTGTCTGAGCCGCGAGAAGCTCGGTTTCGAACTCGAGGCCTTCGTCCAGGTATCGATGCGCAATGACCAG
GAGCAGTGGCACGAGCGCTTCGCCGAGGCGCTGAAGGCCTGGCCGGAGGTGGTGTCGGCGTTCGTCGTGACGGGCGAGAC
GCACTACCTGCTGCGGGTGCTCGCGCACAATCTGAAGCACTACTCGGATTTCGTGCTGAACCAGCTCTACAAGGCGCCGG
GCGTGATGGACATCCGTTCGAACATCGTGCTGCAGACGCTGAAGGACGAGTCGGGCGCGCCCGTGTCGCTGGCGCGCACC
GGCTCCGTCAGAGCGGACTGA

Upstream 100 bases:

>100_bases
GATCATAAGCAAACGTCGCCGAAAGGTGCTTGCGAAATAAACATGGACATTCGGCAAATATCGCAGATAATTTGAACGAT
AGGTAAAACGGGGATCAGAA

Downstream 100 bases:

>100_bases
TACCGTGGAACGTGCCGCCGTGGAACACGAGCGGCGCGGCCGAACCGGGGCCGGCATGCCGGCCGCAGCGCTCGACCTCG
CCCACGAAGATCACGTGGTC

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 166

Protein sequence:

>166_residues
MHAISLDATDCRILAVLQQEGRISNLDLAERISLSPSACLRRMRLLEEQGVIECYRACLSREKLGFELEAFVQVSMRNDQ
EQWHERFAEALKAWPEVVSAFVVTGETHYLLRVLAHNLKHYSDFVLNQLYKAPGVMDIRSNIVLQTLKDESGAPVSLART
GSVRAD

Sequences:

>Translated_166_residues
MHAISLDATDCRILAVLQQEGRISNLDLAERISLSPSACLRRMRLLEEQGVIECYRACLSREKLGFELEAFVQVSMRNDQ
EQWHERFAEALKAWPEVVSAFVVTGETHYLLRVLAHNLKHYSDFVLNQLYKAPGVMDIRSNIVLQTLKDESGAPVSLART
GSVRAD
>Mature_166_residues
MHAISLDATDCRILAVLQQEGRISNLDLAERISLSPSACLRRMRLLEEQGVIECYRACLSREKLGFELEAFVQVSMRNDQ
EQWHERFAEALKAWPEVVSAFVVTGETHYLLRVLAHNLKHYSDFVLNQLYKAPGVMDIRSNIVLQTLKDESGAPVSLART
GSVRAD

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=144, Percent_Identity=35.4166666666667, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=32, Blast_Score=97, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 18786; Mature: 18786

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHAISLDATDCRILAVLQQEGRISNLDLAERISLSPSACLRRMRLLEEQGVIECYRACLS
CCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHH
REKLGFELEAFVQVSMRNDQEQWHERFAEALKAWPEVVSAFVVTGETHYLLRVLAHNLKH
HHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YSDFVLNQLYKAPGVMDIRSNIVLQTLKDESGAPVSLARTGSVRAD
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure
MHAISLDATDCRILAVLQQEGRISNLDLAERISLSPSACLRRMRLLEEQGVIECYRACLS
CCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHH
REKLGFELEAFVQVSMRNDQEQWHERFAEALKAWPEVVSAFVVTGETHYLLRVLAHNLKH
HHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
YSDFVLNQLYKAPGVMDIRSNIVLQTLKDESGAPVSLARTGSVRAD
HHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11157937; 11481430 [H]