Click here to switch to the map view.

The map label for this gene is msrA [H]

Identifier: 238028471

GI number: 238028471

Start: 3323452

End: 3324006

Strand: Reverse

Name: msrA [H]

Synonym: bglu_1g29350

Alternate gene names: 238028471

Gene position: 3324006-3323452 (Counterclockwise)

Preceding gene: 238028473

Following gene: 238028467

Centisome position: 85.09

GC content: 63.96

Gene sequence:

>555_bases
ATGGAAAATCAGGTTTCGACGGCCGTGCTCGGCGGCGGATGTTTCTGGTGCACCGAAGCGGTGTTCCTCGACGTCGTCGG
CGTGCACTCGGTCGAGTCGGGCTATGCCGGCGGCAGCGTCCCCAACCCGACCTATGCCGCGGTCTGCGAAGGTGACACGG
GCCACGCGGAAGTCGTGAAGATCACGTTCGATCCGGCGCGCGTCGGCTATCGCGACATTCTCGAGATCTTCTTCGCCACC
CACGATCCGACCCAGCTGAACCGGCAGGGCGCCGACGTCGGCACGCAATACCGTTCGGTGGTGTTTGCCGAAAACGAGGA
GCAGCGCGCGATCGCGCAAGAGGTGATCGATGCGCTCGAGCGCGACAAGGTGTTCGACGCGCCGATCGTCACGCGCGTCG
AGAAACTCGACGGCAACTTCTGGCCGGCCGAGGAATACCATCGCGACTACTTCGCGCGCAATCCGCAGCAGGGCTATTGC
GCGGCCGTGATCGGGCCGAAGATCGCGAAATTCCGCCAGAAGTTCGCGCATCGCCTGAAATCGAACCGCGGCTGA

Upstream 100 bases:

>100_bases
AGGCGGTCGCGGCGCTTGCCCCGGAGCGGCGCGTCGCGAAGGCGGCCGCCCGGGCCACGGCGATGCGCCCGGCCCCACTG
CTTTATCGAGAGGACATGAC

Downstream 100 bases:

>100_bases
GCGGGCGGGGCGGCACGCGGCGCAGTAACCGGCGGCGGCACAGGAACGTGCCGCCGCTTGTCATTTTGTCGTCGGGTTCG
CCGCAGGGCGGCGGCGCCCA

Product: peptide methionine sulfoxide reductase

Products: NA

Alternate protein names: Protein-methionine-S-oxide reductase; Peptide-methionine (S)-S-oxide reductase; Peptide Met(O) reductase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MENQVSTAVLGGGCFWCTEAVFLDVVGVHSVESGYAGGSVPNPTYAAVCEGDTGHAEVVKITFDPARVGYRDILEIFFAT
HDPTQLNRQGADVGTQYRSVVFAENEEQRAIAQEVIDALERDKVFDAPIVTRVEKLDGNFWPAEEYHRDYFARNPQQGYC
AAVIGPKIAKFRQKFAHRLKSNRG

Sequences:

>Translated_184_residues
MENQVSTAVLGGGCFWCTEAVFLDVVGVHSVESGYAGGSVPNPTYAAVCEGDTGHAEVVKITFDPARVGYRDILEIFFAT
HDPTQLNRQGADVGTQYRSVVFAENEEQRAIAQEVIDALERDKVFDAPIVTRVEKLDGNFWPAEEYHRDYFARNPQQGYC
AAVIGPKIAKFRQKFAHRLKSNRG
>Mature_184_residues
MENQVSTAVLGGGCFWCTEAVFLDVVGVHSVESGYAGGSVPNPTYAAVCEGDTGHAEVVKITFDPARVGYRDILEIFFAT
HDPTQLNRQGADVGTQYRSVVFAENEEQRAIAQEVIDALERDKVFDAPIVTRVEKLDGNFWPAEEYHRDYFARNPQQGYC
AAVIGPKIAKFRQKFAHRLKSNRG

Specific function: Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine [H]

COG id: COG0225

COG function: function code O; Peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrA Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI208609995, Length=157, Percent_Identity=41.4012738853503, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI6912516, Length=157, Percent_Identity=41.4012738853503, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI208609993, Length=141, Percent_Identity=36.1702127659575, Blast_Score=86, Evalue=2e-17,
Organism=Escherichia coli, GI1790665, Length=154, Percent_Identity=40.9090909090909, Blast_Score=129, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17533973, Length=152, Percent_Identity=33.5526315789474, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6320881, Length=160, Percent_Identity=36.25, Blast_Score=99, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24664627, Length=168, Percent_Identity=31.547619047619, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24664631, Length=168, Percent_Identity=30.952380952381, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI45553131, Length=161, Percent_Identity=31.055900621118, Blast_Score=82, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002569 [H]

Pfam domain/function: PF01625 PMSR [H]

EC number: =1.8.4.11 [H]

Molecular weight: Translated: 20402; Mature: 20402

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENQVSTAVLGGGCFWCTEAVFLDVVGVHSVESGYAGGSVPNPTYAAVCEGDTGHAEVVK
CCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEE
ITFDPARVGYRDILEIFFATHDPTQLNRQGADVGTQYRSVVFAENEEQRAIAQEVIDALE
EEECHHHCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHHEEEEECCHHHHHHHHHHHHHHH
RDKVFDAPIVTRVEKLDGNFWPAEEYHRDYFARNPQQGYCAAVIGPKIAKFRQKFAHRLK
HCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEHHCHHHHHHHHHHHHHHH
SNRG
CCCC
>Mature Secondary Structure
MENQVSTAVLGGGCFWCTEAVFLDVVGVHSVESGYAGGSVPNPTYAAVCEGDTGHAEVVK
CCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCCCCEEEEE
ITFDPARVGYRDILEIFFATHDPTQLNRQGADVGTQYRSVVFAENEEQRAIAQEVIDALE
EEECHHHCCHHHHHHHHHCCCCCHHHCCCCCCCCHHHHEEEEECCHHHHHHHHHHHHHHH
RDKVFDAPIVTRVEKLDGNFWPAEEYHRDYFARNPQQGYCAAVIGPKIAKFRQKFAHRLK
HCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEHHCHHHHHHHHHHHHHHH
SNRG
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]