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The map label for this gene is hmrR2 [H]

Identifier: 238028109

GI number: 238028109

Start: 2918417

End: 2918806

Strand: Reverse

Name: hmrR2 [H]

Synonym: bglu_1g25600

Alternate gene names: 238028109

Gene position: 2918806-2918417 (Counterclockwise)

Preceding gene: 238028114

Following gene: 238028108

Centisome position: 74.72

GC content: 60.0

Gene sequence:

>390_bases
GTGAATATTGGTGAAGCCGCTCGCGCCTCGGGTGTCAGCGCGAAGATGATCCGTTACTACGAAAGCGTGGGCCTGATCGA
GCCGGCACAGCGAACCGATGCCGGCTACCGCACGTATCACGAAAACGAAATCCATTCGTTGACGTTCATTCGGCAGGCAC
GTCGGCTCGGCTTCCTTGTCGACGACGTTCGCAAGCTTCTCGCGCTGTGGCAGGATCGCGATCGTGCGAGCGCAGAGGTC
AAGTCGATTGCCCTTGAGCATGTGTCTGAACTGGATCGCCGGATCGCTGAACTGACCGACATGCGCAACACGCTGGCCAG
GTTGGCGGCCCATTGCCATGGAGACGATCGACCCGAGTGCCCGATTCTCGAACGCCTCGCCGATGTGTGA

Upstream 100 bases:

>100_bases
GGGTTTTGTCTTTTATCGCGCAAAACATGCACTCGAACGGCTTCACACGCTCATGACGACATCGCGGTAAGATCAACCGA
CGTTGTCTTGGGAGAGCCGT

Downstream 100 bases:

>100_bases
ATGCACCCGTGCGGTGCATCAATGTCTGTTTTCGGATGCGACTACATCCATAAAAATCCATATAAATCAAACATTTGGCT
TAATTAACGGACAAATTCCA

Product: Cu(I)-responsive transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 129; Mature: 129

Protein sequence:

>129_residues
MNIGEAARASGVSAKMIRYYESVGLIEPAQRTDAGYRTYHENEIHSLTFIRQARRLGFLVDDVRKLLALWQDRDRASAEV
KSIALEHVSELDRRIAELTDMRNTLARLAAHCHGDDRPECPILERLADV

Sequences:

>Translated_129_residues
MNIGEAARASGVSAKMIRYYESVGLIEPAQRTDAGYRTYHENEIHSLTFIRQARRLGFLVDDVRKLLALWQDRDRASAEV
KSIALEHVSELDRRIAELTDMRNTLARLAAHCHGDDRPECPILERLADV
>Mature_129_residues
MNIGEAARASGVSAKMIRYYESVGLIEPAQRTDAGYRTYHENEIHSLTFIRQARRLGFLVDDVRKLLALWQDRDRASAEV
KSIALEHVSELDRRIAELTDMRNTLARLAAHCHGDDRPECPILERLADV

Specific function: Transcriptional regulator involved in acid tolerance. Binds copper [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=44.8818897637795, Blast_Score=122, Evalue=6e-30,
Organism=Escherichia coli, GI1789687, Length=127, Percent_Identity=40.1574803149606, Blast_Score=88, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011789
- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 14688; Mature: 14688

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGEAARASGVSAKMIRYYESVGLIEPAQRTDAGYRTYHENEIHSLTFIRQARRLGFLV
CCCCCHHHHCCCHHHHHHHHHHHCCCCCHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHH
DDVRKLLALWQDRDRASAEVKSIALEHVSELDRRIAELTDMRNTLARLAAHCHGDDRPEC
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILERLADV
HHHHHHHCC
>Mature Secondary Structure
MNIGEAARASGVSAKMIRYYESVGLIEPAQRTDAGYRTYHENEIHSLTFIRQARRLGFLV
CCCCCHHHHCCCHHHHHHHHHHHCCCCCHHHCCCCCHHCCCHHHHHHHHHHHHHHHHHHH
DDVRKLLALWQDRDRASAEVKSIALEHVSELDRRIAELTDMRNTLARLAAHCHGDDRPEC
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PILERLADV
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11481431 [H]