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The map label for this gene is lolC [H]

Identifier: 238028009

GI number: 238028009

Start: 2791388

End: 2792641

Strand: Reverse

Name: lolC [H]

Synonym: bglu_1g24580

Alternate gene names: 238028009

Gene position: 2792641-2791388 (Counterclockwise)

Preceding gene: 238028014

Following gene: 238028008

Centisome position: 71.49

GC content: 67.22

Gene sequence:

>1254_bases
TTGAAACTCCCGTACGAATGGCAGATCGGCTGGCGCTATACGCGTGCCGGCAAACGCACGACCGGCAACGGTTTCATCTC
GTTCATCGCGGCCGTGTCGATGCTCGGCATCGCGCTCGGCGTCGCGGCGCTGATCGTCGTGCTGTCGGTGATGAACGGCT
TTCAGACCCAGGTGCGCGACCGCATGCTGTCGGTGCTCGCGCACGTGGAGATCTTCTCGCCGACCGGCTCGATGCCGGAC
TGGCAGCGGACCGCCAGCGAGGCGCGCCGCAACCCGGAGGTGATCGGCAGCGCGCCCTATGTCGAGGCCCAGGCCTTGCT
GACGCGCCAGGATGCCGTGAGCGGCGTGATGCTGCGCGGCGTCGACCCCACCCTCGAGCCGCAGGTGTCGGACGTCGGCA
AGGACATGCGGGCCGGCTCGCTCGCGGCGCTGCAGCCGGGCGGCTTCGGCATCGTGCTGGGCACCGCGCTGGCCAGCAAT
CTCGGCGTGACGGTGGGCGACAAGGTCACGCTGGTCGCGCCCGAAGGCACCATCACGCCGGCCGGCATGCTGCCGCGCCT
GAAGCAGTTCACGGTGGTGGGCGTGTTCGAGTCGGGGCATTACGAATACGACAGCACGCTCGCGATGATCGACATCCACG
ACGCGCAGACGCTGTTCCGCCTGCCCGCGCCGACCGGCGTGCGGCTGCGCCTGAAGGACATGCAGCGCGCGCCGCAGGTG
GCGGTGGAGCTGTCGCATTCGCTGTCGGGCGAGCTCTACATCCGTGACTGGACCCAGCAGAACAAGACCTGGTTCTCGGC
CGTGAAGATCGAGAAGCGCATGATGTTCATCATCCTGACGCTGATCATCGCGGTGGCGGCGTTCAATCTCGTCTCGTCGC
TGGTGATGACGGTCACCAACAAGCAGGCCGACATCGCGATCCTACGCACGCTCGGCGCGCAGCCCGGCTCGATCATGAAG
ATCTTCGTGGTGCAGGGCGTGACGGTGGGCTTCGTCGGCACGCTCTCGGGCGTCGCGCTCGGCAGCCTGATCGCCTGGAG
CATTCCGTGGCTGATTCCGATGATCGAGCACGCGTTCGGCGTGCAGTTCCTGCCGCCGTCGGTCTATTTCATCAGCGAAC
TGCCGTCGCAGCTCGTCGCGGGCGACGTGATCCGGATCGGCGTGATCGCGTTCGTGCTGTCGGCCGTGGCCACGCTCTAT
CCGAGCTGGCGCGCCGCGAAGGTGCGTCCGGCGGAGGCGCTGCGCTATGAATGA

Upstream 100 bases:

>100_bases
ATGTGGCAAACTTCGCGCGTGATCGACGATGCGATGCCGCGCGCCGCGTGCCGGAATGCGCGGCCGGCTGCGGCCGCCGC
AACCAGTGAAAAGGACCCGC

Downstream 100 bases:

>100_bases
CCGAATCGTGGAACAGGCAATGAACCAGAACGACAATCAACGGGCCGGCGCGCGCGAAGTCGTGCTCGAGGCGAGCGGCA
TCACCAAGTCGTTCGGCCAG

Product: lipoprotein releasing system, transmembrane protein, LolC/E family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MKLPYEWQIGWRYTRAGKRTTGNGFISFIAAVSMLGIALGVAALIVVLSVMNGFQTQVRDRMLSVLAHVEIFSPTGSMPD
WQRTASEARRNPEVIGSAPYVEAQALLTRQDAVSGVMLRGVDPTLEPQVSDVGKDMRAGSLAALQPGGFGIVLGTALASN
LGVTVGDKVTLVAPEGTITPAGMLPRLKQFTVVGVFESGHYEYDSTLAMIDIHDAQTLFRLPAPTGVRLRLKDMQRAPQV
AVELSHSLSGELYIRDWTQQNKTWFSAVKIEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMK
IFVVQGVTVGFVGTLSGVALGSLIAWSIPWLIPMIEHAFGVQFLPPSVYFISELPSQLVAGDVIRIGVIAFVLSAVATLY
PSWRAAKVRPAEALRYE

Sequences:

>Translated_417_residues
MKLPYEWQIGWRYTRAGKRTTGNGFISFIAAVSMLGIALGVAALIVVLSVMNGFQTQVRDRMLSVLAHVEIFSPTGSMPD
WQRTASEARRNPEVIGSAPYVEAQALLTRQDAVSGVMLRGVDPTLEPQVSDVGKDMRAGSLAALQPGGFGIVLGTALASN
LGVTVGDKVTLVAPEGTITPAGMLPRLKQFTVVGVFESGHYEYDSTLAMIDIHDAQTLFRLPAPTGVRLRLKDMQRAPQV
AVELSHSLSGELYIRDWTQQNKTWFSAVKIEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMK
IFVVQGVTVGFVGTLSGVALGSLIAWSIPWLIPMIEHAFGVQFLPPSVYFISELPSQLVAGDVIRIGVIAFVLSAVATLY
PSWRAAKVRPAEALRYE
>Mature_417_residues
MKLPYEWQIGWRYTRAGKRTTGNGFISFIAAVSMLGIALGVAALIVVLSVMNGFQTQVRDRMLSVLAHVEIFSPTGSMPD
WQRTASEARRNPEVIGSAPYVEAQALLTRQDAVSGVMLRGVDPTLEPQVSDVGKDMRAGSLAALQPGGFGIVLGTALASN
LGVTVGDKVTLVAPEGTITPAGMLPRLKQFTVVGVFESGHYEYDSTLAMIDIHDAQTLFRLPAPTGVRLRLKDMQRAPQV
AVELSHSLSGELYIRDWTQQNKTWFSAVKIEKRMMFIILTLIIAVAAFNLVSSLVMTVTNKQADIAILRTLGAQPGSIMK
IFVVQGVTVGFVGTLSGVALGSLIAWSIPWLIPMIEHAFGVQFLPPSVYFISELPSQLVAGDVIRIGVIAFVLSAVATLY
PSWRAAKVRPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=416, Percent_Identity=32.9326923076923, Blast_Score=212, Evalue=4e-56,
Organism=Escherichia coli, GI1787360, Length=425, Percent_Identity=36.2352941176471, Blast_Score=199, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45125; Mature: 45125

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPYEWQIGWRYTRAGKRTTGNGFISFIAAVSMLGIALGVAALIVVLSVMNGFQTQVRD
CCCCCEEEECEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLSVLAHVEIFSPTGSMPDWQRTASEARRNPEVIGSAPYVEAQALLTRQDAVSGVMLRG
HHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
VDPTLEPQVSDVGKDMRAGSLAALQPGGFGIVLGTALASNLGVTVGDKVTLVAPEGTITP
CCCCCCCCHHHHCCHHCCCCEEEECCCCCEEHHHHHHHHCCCEEECCEEEEECCCCCCCC
AGMLPRLKQFTVVGVFESGHYEYDSTLAMIDIHDAQTLFRLPAPTGVRLRLKDMQRAPQV
CHHCCHHHHEEEEEEEECCCEECCCEEEEEEECCCHHHEECCCCCCCEEEHHHHHCCHHH
AVELSHSLSGELYIRDWTQQNKTWFSAVKIEKRMMFIILTLIIAVAAFNLVSSLVMTVTN
HHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KQADIAILRTLGAQPGSIMKIFVVQGVTVGFVGTLSGVALGSLIAWSIPWLIPMIEHAFG
CCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VQFLPPSVYFISELPSQLVAGDVIRIGVIAFVLSAVATLYPSWRAAKVRPAEALRYE
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MKLPYEWQIGWRYTRAGKRTTGNGFISFIAAVSMLGIALGVAALIVVLSVMNGFQTQVRD
CCCCCEEEECEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RMLSVLAHVEIFSPTGSMPDWQRTASEARRNPEVIGSAPYVEAQALLTRQDAVSGVMLRG
HHHHHHHHHEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEC
VDPTLEPQVSDVGKDMRAGSLAALQPGGFGIVLGTALASNLGVTVGDKVTLVAPEGTITP
CCCCCCCCHHHHCCHHCCCCEEEECCCCCEEHHHHHHHHCCCEEECCEEEEECCCCCCCC
AGMLPRLKQFTVVGVFESGHYEYDSTLAMIDIHDAQTLFRLPAPTGVRLRLKDMQRAPQV
CHHCCHHHHEEEEEEEECCCEECCCEEEEEEECCCHHHEECCCCCCCEEEHHHHHCCHHH
AVELSHSLSGELYIRDWTQQNKTWFSAVKIEKRMMFIILTLIIAVAAFNLVSSLVMTVTN
HHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KQADIAILRTLGAQPGSIMKIFVVQGVTVGFVGTLSGVALGSLIAWSIPWLIPMIEHAFG
CCHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VQFLPPSVYFISELPSQLVAGDVIRIGVIAFVLSAVATLYPSWRAAKVRPAEALRYE
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]