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The map label for this gene is luxQ [H]

Identifier: 238027849

GI number: 238027849

Start: 2487878

End: 2489824

Strand: Direct

Name: luxQ [H]

Synonym: bglu_1g22800

Alternate gene names: 238027849

Gene position: 2487878-2489824 (Clockwise)

Preceding gene: 238027848

Following gene: 238027850

Centisome position: 63.69

GC content: 73.86

Gene sequence:

>1947_bases
ATGGCCGCGTTAAGCCCGCTGATCCTCAACGTCGACGACAACGAGGGCGCCCGCTATGCCAAGACGCGCGTGCTGATCCA
CGCCGGCTACCAGGTGATCGAGGCCGGCACCGGACAGGACGCGCTCGACCTGGTCGAGGCGCGCCGCCCGGCGCTGGTGC
TGCTCGACGTGCGGCTGCCCGACATCAGCGGCATCGACGTCTGCTCGCAGATCAAGCGCGACGCGCGCACGCGCTCGACG
CTGGTGCTGCAGACCTCCGCCGCGGCGGTGCAGTCGCTCGACAAGGTGCGCGCGCTCGACGGCGGCGCCGACAGCTATCT
GACCGAACCGATCGCGCCGGCCGAACTGGTCGCGAACGTGCGCGCGCTGCTGCGCCTGCACCGGGCCGAGGAGGCGCTGC
GCGACGCCGACCGCCGCAAGGACCAGTTCCTCGCCACACTCGCGCATGAGCTGCGCAATCCGCTCGCCCCGATCCGCAAC
GCGATCGAGCTGATGGACCCCAAATACCAAGCGGCCGAGGCGCTGGTGCACGACGCGCGCATGATCGCGCGCCGCCAGGT
GGACCATCTGAGCCGGCTGGTGGACGACCTGCTCGACGTGTCGCGCATCACTCACGGCAAGATCGCGCTGCGCATGGAGC
CGGTGGACATCGAGGCGGCGGTGGCCGCCGCGGTGGAAACCAGCCAGCCGGCCATGGAGCGCAAGCACCACGTGCTGCGC
GTGAGCATGCCGCCGCTGCCCTGCGTGGTGAACGGCGACGCGATCCGGATCTCGCAGGTGATCGCCAACCTGCTGTCGAA
CGCGGCCAAGTACACGCCCGACGGCGGACGCATCGAGCTCGGCGTGGCGGTCGCGCCCGGCGCCGTCGAGATCAGCGTGG
CCGACAACGGCATCGGCATCGCGCCGGCCGAACTCGACGAGGTGTTCAACCTGTTCATGCAGTCGGCCGACTCGGTCAAG
CGCTCCGAGGGCGGGCTCGGCATCGGTCTGTCGCTCGCGCGCACGCTCACCGAGCTGCACGGCGGCACCATCGTCGCGAG
TTCGGACGGCATCGGCCACGGCTCGCGGTTCGTGGTGCGGCTGCCGCTCGCCGTGCCCGACCCGGCCGCCGCCGGCCCGG
CCGCCGCCGACGCCGCGCCGCGCCCGCAGCGCCGCGTGATGGTGGTGGACGACAGCGTGGACGGCGCCGAATCGATGTCG
GTGCTGCTGCGCATCCTCGGCCACGAGGTGCGCACGCTCTACGAGGGCACCTCGGCGATCGCGGCCGCGGCCGCGTTCCA
GCCCGAGGTGGTGATGCTCGACATCGGCCTGCCCGGCATGGACGGCTACGAGATCGCGCGCGCCCTGCGCGCCCTGCCCG
CCACCGCCGGCGCGCTGCTGATCGCGCTGACCGGCTACGGCCAGGAAAGCGACCGCCAGCGCACGCGCGCGGCCGGCTTC
GATCACCATCTCGTGAAGCCGGCCACGCTCGAGGACATCGAGCGCGCGATCGCCACTGTCGGCACCGACGCGGCGGCGCG
CCGGCACCGCGCCGGCCAACCGGGCCGCCTCGCCCGGCAGCGAGCGGCCCCGGCCCGCGGGCCGGAGCGGGCCGCCGAAG
CGAGTCACCTGAGCGGGCGGACGCCGGCCTCGGACGGGCCGCCCGCTCGGCCCGAGCCGACGAGCCGATCCGCAGCGCCG
GCCTCGCCCGCCCCCACACTGGCGCGCGGCCCCGGCGCAGCGCCGGCCAACCGCCCGGCTCGTCGCCGCGACGGTCGCGC
GACGCCTCGACATGCTTTCCACTGCCTTGCGGCGCCGCGCCCGCAGGCCGCTGCCGGCGCGGCGGCGCCGGGTTCGGGTA
CGAGCGTTGCTGCCTGCTCGGTGAGCCTCGGGATCGCGATCCCGGCCTGCGTCCACCAACAGGAGCGTCGCCATGTCCGG
CAGCATGGATCAAACCACGATGCGTGA

Upstream 100 bases:

>100_bases
CGCTGCCGCTGCGCTTCGCGGCCCCGGCCCAGGCGCACCACGACGGCGCCGCCGCTGCCGGCGGCCTCACCGACACCCCG
ACTTCGCGTGGAGATGACGC

Downstream 100 bases:

>100_bases
CCCGCTCACGCACTACCCGCGTTCCGCCTTCGACAAGCAGCCCCGGCCCGCTCCGGGCCTCGCCGGCCAGATGCGCCCGC
GCCCCGACCACGGCGAAACC

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 648; Mature: 647

Protein sequence:

>648_residues
MAALSPLILNVDDNEGARYAKTRVLIHAGYQVIEAGTGQDALDLVEARRPALVLLDVRLPDISGIDVCSQIKRDARTRST
LVLQTSAAAVQSLDKVRALDGGADSYLTEPIAPAELVANVRALLRLHRAEEALRDADRRKDQFLATLAHELRNPLAPIRN
AIELMDPKYQAAEALVHDARMIARRQVDHLSRLVDDLLDVSRITHGKIALRMEPVDIEAAVAAAVETSQPAMERKHHVLR
VSMPPLPCVVNGDAIRISQVIANLLSNAAKYTPDGGRIELGVAVAPGAVEISVADNGIGIAPAELDEVFNLFMQSADSVK
RSEGGLGIGLSLARTLTELHGGTIVASSDGIGHGSRFVVRLPLAVPDPAAAGPAAADAAPRPQRRVMVVDDSVDGAESMS
VLLRILGHEVRTLYEGTSAIAAAAAFQPEVVMLDIGLPGMDGYEIARALRALPATAGALLIALTGYGQESDRQRTRAAGF
DHHLVKPATLEDIERAIATVGTDAAARRHRAGQPGRLARQRAAPARGPERAAEASHLSGRTPASDGPPARPEPTSRSAAP
ASPAPTLARGPGAAPANRPARRRDGRATPRHAFHCLAAPRPQAAAGAAAPGSGTSVAACSVSLGIAIPACVHQQERRHVR
QHGSNHDA

Sequences:

>Translated_648_residues
MAALSPLILNVDDNEGARYAKTRVLIHAGYQVIEAGTGQDALDLVEARRPALVLLDVRLPDISGIDVCSQIKRDARTRST
LVLQTSAAAVQSLDKVRALDGGADSYLTEPIAPAELVANVRALLRLHRAEEALRDADRRKDQFLATLAHELRNPLAPIRN
AIELMDPKYQAAEALVHDARMIARRQVDHLSRLVDDLLDVSRITHGKIALRMEPVDIEAAVAAAVETSQPAMERKHHVLR
VSMPPLPCVVNGDAIRISQVIANLLSNAAKYTPDGGRIELGVAVAPGAVEISVADNGIGIAPAELDEVFNLFMQSADSVK
RSEGGLGIGLSLARTLTELHGGTIVASSDGIGHGSRFVVRLPLAVPDPAAAGPAAADAAPRPQRRVMVVDDSVDGAESMS
VLLRILGHEVRTLYEGTSAIAAAAAFQPEVVMLDIGLPGMDGYEIARALRALPATAGALLIALTGYGQESDRQRTRAAGF
DHHLVKPATLEDIERAIATVGTDAAARRHRAGQPGRLARQRAAPARGPERAAEASHLSGRTPASDGPPARPEPTSRSAAP
ASPAPTLARGPGAAPANRPARRRDGRATPRHAFHCLAAPRPQAAAGAAAPGSGTSVAACSVSLGIAIPACVHQQERRHVR
QHGSNHDA
>Mature_647_residues
AALSPLILNVDDNEGARYAKTRVLIHAGYQVIEAGTGQDALDLVEARRPALVLLDVRLPDISGIDVCSQIKRDARTRSTL
VLQTSAAAVQSLDKVRALDGGADSYLTEPIAPAELVANVRALLRLHRAEEALRDADRRKDQFLATLAHELRNPLAPIRNA
IELMDPKYQAAEALVHDARMIARRQVDHLSRLVDDLLDVSRITHGKIALRMEPVDIEAAVAAAVETSQPAMERKHHVLRV
SMPPLPCVVNGDAIRISQVIANLLSNAAKYTPDGGRIELGVAVAPGAVEISVADNGIGIAPAELDEVFNLFMQSADSVKR
SEGGLGIGLSLARTLTELHGGTIVASSDGIGHGSRFVVRLPLAVPDPAAAGPAAADAAPRPQRRVMVVDDSVDGAESMSV
LLRILGHEVRTLYEGTSAIAAAAAFQPEVVMLDIGLPGMDGYEIARALRALPATAGALLIALTGYGQESDRQRTRAAGFD
HHLVKPATLEDIERAIATVGTDAAARRHRAGQPGRLARQRAAPARGPERAAEASHLSGRTPASDGPPARPEPTSRSAAPA
SPAPTLARGPGAAPANRPARRRDGRATPRHAFHCLAAPRPQAAAGAAAPGSGTSVAACSVSLGIAIPACVHQQERRHVRQ
HGSNHDA

Specific function: At low cell density, in absence of AI-2 (autoinducer 2), luxQ has a kinase activity and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is t

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=378, Percent_Identity=31.4814814814815, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788713, Length=364, Percent_Identity=27.7472527472527, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=33.0827067669173, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1786912, Length=254, Percent_Identity=32.2834645669291, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=29.5652173913043, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790436, Length=270, Percent_Identity=31.1111111111111, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI87081816, Length=363, Percent_Identity=29.7520661157025, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789149, Length=281, Percent_Identity=29.1814946619217, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1786600, Length=310, Percent_Identity=26.1290322580645, Blast_Score=92, Evalue=9e-20,
Organism=Escherichia coli, GI1786783, Length=255, Percent_Identity=26.2745098039216, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790346, Length=251, Percent_Identity=26.2948207171315, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=38.135593220339, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790551, Length=221, Percent_Identity=28.5067873303167, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=27.3913043478261, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1788549, Length=225, Percent_Identity=25.7777777777778, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788279, Length=310, Percent_Identity=24.5161290322581, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=259, Percent_Identity=27.4131274131274, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790300, Length=234, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082012, Length=122, Percent_Identity=37.7049180327869, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1786911, Length=125, Percent_Identity=37.6, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790861, Length=234, Percent_Identity=28.6324786324786, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789808, Length=231, Percent_Identity=25.974025974026, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI1786784, Length=118, Percent_Identity=34.7457627118644, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 68151; Mature: 68020

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAALSPLILNVDDNEGARYAKTRVLIHAGYQVIEAGTGQDALDLVEARRPALVLLDVRLP
CCCCCCEEEEECCCCCCCHHHHEEEEECCCEEEECCCCCHHHHHHHCCCCEEEEEEEECC
DISGIDVCSQIKRDARTRSTLVLQTSAAAVQSLDKVRALDGGADSYLTEPIAPAELVANV
CCCCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHH
RALLRLHRAEEALRDADRRKDQFLATLAHELRNPLAPIRNAIELMDPKYQAAEALVHDAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHH
MIARRQVDHLSRLVDDLLDVSRITHGKIALRMEPVDIEAAVAAAVETSQPAMERKHHVLR
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHCCCEEE
VSMPPLPCVVNGDAIRISQVIANLLSNAAKYTPDGGRIELGVAVAPGAVEISVADNGIGI
EECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEEECCCCCC
APAELDEVFNLFMQSADSVKRSEGGLGIGLSLARTLTELHGGTIVASSDGIGHGSRFVVR
CHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEE
LPLAVPDPAAAGPAAADAAPRPQRRVMVVDDSVDGAESMSVLLRILGHEVRTLYEGTSAI
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHH
AAAAAFQPEVVMLDIGLPGMDGYEIARALRALPATAGALLIALTGYGQESDRQRTRAAGF
HHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHCEEEEEEECCCCCHHHHHHHHCCC
DHHLVKPATLEDIERAIATVGTDAAARRHRAGQPGRLARQRAAPARGPERAAEASHLSGR
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCC
TPASDGPPARPEPTSRSAAPASPAPTLARGPGAAPANRPARRRDGRATPRHAFHCLAAPR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHCCCC
PQAAAGAAAPGSGTSVAACSVSLGIAIPACVHQQERRHVRQHGSNHDA
CCCCCCCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AALSPLILNVDDNEGARYAKTRVLIHAGYQVIEAGTGQDALDLVEARRPALVLLDVRLP
CCCCCEEEEECCCCCCCHHHHEEEEECCCEEEECCCCCHHHHHHHCCCCEEEEEEEECC
DISGIDVCSQIKRDARTRSTLVLQTSAAAVQSLDKVRALDGGADSYLTEPIAPAELVANV
CCCCHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCHHHHCCCCCHHHHHHHH
RALLRLHRAEEALRDADRRKDQFLATLAHELRNPLAPIRNAIELMDPKYQAAEALVHDAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHH
MIARRQVDHLSRLVDDLLDVSRITHGKIALRMEPVDIEAAVAAAVETSQPAMERKHHVLR
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCHHHHHCCCEEE
VSMPPLPCVVNGDAIRISQVIANLLSNAAKYTPDGGRIELGVAVAPGAVEISVADNGIGI
EECCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEEECCCCCC
APAELDEVFNLFMQSADSVKRSEGGLGIGLSLARTLTELHGGTIVASSDGIGHGSRFVVR
CHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEE
LPLAVPDPAAAGPAAADAAPRPQRRVMVVDDSVDGAESMSVLLRILGHEVRTLYEGTSAI
ECCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCHHHH
AAAAAFQPEVVMLDIGLPGMDGYEIARALRALPATAGALLIALTGYGQESDRQRTRAAGF
HHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHCEEEEEEECCCCCHHHHHHHHCCC
DHHLVKPATLEDIERAIATVGTDAAARRHRAGQPGRLARQRAAPARGPERAAEASHLSGR
CCCCCCCCCHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHCCCCCCHHHHHHHHHCCCC
TPASDGPPARPEPTSRSAAPASPAPTLARGPGAAPANRPARRRDGRATPRHAFHCLAAPR
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHCCCC
PQAAAGAAAPGSGTSVAACSVSLGIAIPACVHQQERRHVRQHGSNHDA
CCCCCCCCCCCCCCCEEEEEEHHCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10952301; 12176318 [H]