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The map label for this gene is rsbRA [H]

Identifier: 238027844

GI number: 238027844

Start: 2483530

End: 2484393

Strand: Direct

Name: rsbRA [H]

Synonym: bglu_1g22750

Alternate gene names: 238027844

Gene position: 2483530-2484393 (Clockwise)

Preceding gene: 238027843

Following gene: 238027845

Centisome position: 63.57

GC content: 67.82

Gene sequence:

>864_bases
ATGAATCCACCGAACCGCATTGCGCTGGCCGAAGTCCTCTCGCGAAACCGCGCCACCCTGCTCAAGGACTGGCTCGACCA
GCACCTGTCGACGGCGCAGCGGCGCGGGCTGACCACCGACGCCGAGATGTCGGACCAGTTCCGCGGCTTCCTCGGCATCT
TCATCGACACGCTCGCCAGCGTGGACGCCATCGACGCCGCGCGGCCCGAATGGGAGCCGGTGCGCGAGTTCCTCGCCGAG
ATCTCGAAGCACCGCGTGCGGCTCGGCTTCACGCCGGTCGAGACCGCCACCTTCGTGTTCTCGCTGAAGCAGCCGCTCTA
CACGCTGCTGCGCAACGAGTTCGGCAACGACGCGGCCGCGCTCGCCGACCTGAGCTGGTCCGTCAACGTGCTGCTCGACG
CGCTCGGCCTCTACACCACCGAGGTGTACCAGCGCAGCCGCGAGGCCATCATCCTGCGCCAGCAGGAGGAACTGCTCGAG
CTGTCCACGCCGGTGGTGCAGCTGTGGGAAGGCATCCTCGCATTGCCGCTGATCGGCACGCTCGACTCGGCGCGCACCCA
GATCGTGATGGAAAGCCTGCTGCAGAAGATCGTCGAGACGGGCGCCGGCATCGCCATCATCGACATCACCGGCGTGCCGA
CCGTGGACACGCTGGTCGCGCAGCACCTGCTCAAGACGGTCGCCGCGGCACGCCTGATGGGCGCGGACTGCATCATCAGC
GGGATCCGCCCGCAGATCGCGCAGACCATCGTCCACCTCGGCGTGGACCTGACCAACGTCACGACCAAATCGACGCTCGC
CGATGCCTTCGTCGTCGCGCTCAAGCGCAACGGCTCGAGCATCGCCGGCGGCGCCGTCGAGTGA

Upstream 100 bases:

>100_bases
CAGGATGCGCCGGACCGGCGGCGGCAGCTCGCGCGCCGGGCTGCGCGGCCTGCGCGAAGCCACGGACCAGGCACGCTCGC
CGATCATTTACGGAGCATTC

Downstream 100 bases:

>100_bases
GGCGCGCGACATGGACCGCATTCCGATATTGCAGCTCGGAGACTGCCTGATCATCGCGATCCAGGCCGACATGCACGACC
GGCTCGCCCTGTCGCTGCAG

Product: Anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MNPPNRIALAEVLSRNRATLLKDWLDQHLSTAQRRGLTTDAEMSDQFRGFLGIFIDTLASVDAIDAARPEWEPVREFLAE
ISKHRVRLGFTPVETATFVFSLKQPLYTLLRNEFGNDAAALADLSWSVNVLLDALGLYTTEVYQRSREAIILRQQEELLE
LSTPVVQLWEGILALPLIGTLDSARTQIVMESLLQKIVETGAGIAIIDITGVPTVDTLVAQHLLKTVAAARLMGADCIIS
GIRPQIAQTIVHLGVDLTNVTTKSTLADAFVVALKRNGSSIAGGAVE

Sequences:

>Translated_287_residues
MNPPNRIALAEVLSRNRATLLKDWLDQHLSTAQRRGLTTDAEMSDQFRGFLGIFIDTLASVDAIDAARPEWEPVREFLAE
ISKHRVRLGFTPVETATFVFSLKQPLYTLLRNEFGNDAAALADLSWSVNVLLDALGLYTTEVYQRSREAIILRQQEELLE
LSTPVVQLWEGILALPLIGTLDSARTQIVMESLLQKIVETGAGIAIIDITGVPTVDTLVAQHLLKTVAAARLMGADCIIS
GIRPQIAQTIVHLGVDLTNVTTKSTLADAFVVALKRNGSSIAGGAVE
>Mature_287_residues
MNPPNRIALAEVLSRNRATLLKDWLDQHLSTAQRRGLTTDAEMSDQFRGFLGIFIDTLASVDAIDAARPEWEPVREFLAE
ISKHRVRLGFTPVETATFVFSLKQPLYTLLRNEFGNDAAALADLSWSVNVLLDALGLYTTEVYQRSREAIILRQQEELLE
LSTPVVQLWEGILALPLIGTLDSARTQIVMESLLQKIVETGAGIAIIDITGVPTVDTLVAQHLLKTVAAARLMGADCIIS
GIRPQIAQTIVHLGVDLTNVTTKSTLADAFVVALKRNGSSIAGGAVE

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31295; Mature: 31295

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPPNRIALAEVLSRNRATLLKDWLDQHLSTAQRRGLTTDAEMSDQFRGFLGIFIDTLAS
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
VDAIDAARPEWEPVREFLAEISKHRVRLGFTPVETATFVFSLKQPLYTLLRNEFGNDAAA
HHHHHCCCCCHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LADLSWSVNVLLDALGLYTTEVYQRSREAIILRQQEELLELSTPVVQLWEGILALPLIGT
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LDSARTQIVMESLLQKIVETGAGIAIIDITGVPTVDTLVAQHLLKTVAAARLMGADCIIS
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIRPQIAQTIVHLGVDLTNVTTKSTLADAFVVALKRNGSSIAGGAVE
CCCHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNPPNRIALAEVLSRNRATLLKDWLDQHLSTAQRRGLTTDAEMSDQFRGFLGIFIDTLAS
CCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
VDAIDAARPEWEPVREFLAEISKHRVRLGFTPVETATFVFSLKQPLYTLLRNEFGNDAAA
HHHHHCCCCCHHHHHHHHHHHHHCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LADLSWSVNVLLDALGLYTTEVYQRSREAIILRQQEELLELSTPVVQLWEGILALPLIGT
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LDSARTQIVMESLLQKIVETGAGIAIIDITGVPTVDTLVAQHLLKTVAAARLMGADCIIS
HHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
GIRPQIAQTIVHLGVDLTNVTTKSTLADAFVVALKRNGSSIAGGAVE
CCCHHHHHHHHHHCCCHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]