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The map label for this gene is soxR [H]

Identifier: 238027831

GI number: 238027831

Start: 2467081

End: 2467566

Strand: Reverse

Name: soxR [H]

Synonym: bglu_1g22620

Alternate gene names: 238027831

Gene position: 2467566-2467081 (Counterclockwise)

Preceding gene: 238027833

Following gene: 238027830

Centisome position: 63.17

GC content: 65.23

Gene sequence:

>486_bases
GTGAACGAGGGAACAATCACAATCGGCGAACTGGCGAAACGCTCGGGTGTAGCAGTGAGCGCAATCCGCTTCTATGACGA
TCAAGGGCTGATCAGCAGCACCCGAGCTGCCGGCGGTCAACGCCAGTACCGGCGGGAGGCGCTGCGCCGGGTCGGATTCA
TTCGTGCGGCGCAGGCCGTCGGACTGAGCCTTTCGGACATTCAAGCGGCCCTCGACTCCCTGCCGGGGCAGCGCACTCCG
ACAAAGCAGGACTGGGCGCGGCTGTCGCGGGCGTGGCAACCTCTGCTTCAGGCGCGCATTGATAGGCTCGTCGCATTGCG
CGACAGGCTCGCATCTTGCGTGGGCTGCGGGTGCCTGTCGCTCAAGGCGTGCGCGCTCCATAATCCGGGCGATATCGCGC
ATCGACTCGGAAGTGGCCCGCGCTATCTACAAGGCGATACGCCGAGTACAACCTTGGCCAAGGATGGCCGCCGCGGGCGG
CGTTGA

Upstream 100 bases:

>100_bases
CAATGTCGTCGCGCATATGGCTGCCTCCTGATTCCGGGAATGAAGCTGCATGGTACAGGTTCAAGTAAACTTGAGGTCAA
CACATGTGCGGGGAAGCTTC

Downstream 100 bases:

>100_bases
AGATTGCACACGCATGGTCTCCCACGCAGAAGCCTATTTGAAAGACTTTCATCGCCGCCGGGCCGGCGCCACCCGTCGCG
CCTTCGGCAATCGGCCGGCA

Product: Redox-sensitive transcriptional activator SoxR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 161; Mature: 161

Protein sequence:

>161_residues
MNEGTITIGELAKRSGVAVSAIRFYDDQGLISSTRAAGGQRQYRREALRRVGFIRAAQAVGLSLSDIQAALDSLPGQRTP
TKQDWARLSRAWQPLLQARIDRLVALRDRLASCVGCGCLSLKACALHNPGDIAHRLGSGPRYLQGDTPSTTLAKDGRRGR
R

Sequences:

>Translated_161_residues
MNEGTITIGELAKRSGVAVSAIRFYDDQGLISSTRAAGGQRQYRREALRRVGFIRAAQAVGLSLSDIQAALDSLPGQRTP
TKQDWARLSRAWQPLLQARIDRLVALRDRLASCVGCGCLSLKACALHNPGDIAHRLGSGPRYLQGDTPSTTLAKDGRRGR
R
>Mature_161_residues
MNEGTITIGELAKRSGVAVSAIRFYDDQGLISSTRAAGGQRQYRREALRRVGFIRAAQAVGLSLSDIQAALDSLPGQRTP
TKQDWARLSRAWQPLLQARIDRLVALRDRLASCVGCGCLSLKACALHNPGDIAHRLGSGPRYLQGDTPSTTLAKDGRRGR
R

Specific function: Activates The Transcription Of The Soxs Gene Which Itself Controls The Superoxide Response Regulon. Soxr Contains A 2fe-2s Iron-Sulfur Cluster That May Act As A Redox Sensor System That Recognizes Superoxide. The Variable Redox State Of The Fe-S Cluster I

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790498, Length=141, Percent_Identity=48.936170212766, Blast_Score=137, Evalue=2e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR010211
- InterPro:   IPR015358 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 17467; Mature: 17467

Theoretical pI: Translated: 11.46; Mature: 11.46

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEGTITIGELAKRSGVAVSAIRFYDDQGLISSTRAAGGQRQYRREALRRVGFIRAAQAV
CCCCCEEHHHHHHHCCCCHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GLSLSDIQAALDSLPGQRTPTKQDWARLSRAWQPLLQARIDRLVALRDRLASCVGCGCLS
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
LKACALHNPGDIAHRLGSGPRYLQGDTPSTTLAKDGRRGRR
HHHHHCCCCHHHHHHHCCCCCEECCCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MNEGTITIGELAKRSGVAVSAIRFYDDQGLISSTRAAGGQRQYRREALRRVGFIRAAQAV
CCCCCEEHHHHHHHCCCCHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
GLSLSDIQAALDSLPGQRTPTKQDWARLSRAWQPLLQARIDRLVALRDRLASCVGCGCLS
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHH
LKACALHNPGDIAHRLGSGPRYLQGDTPSTTLAKDGRRGRR
HHHHHCCCCHHHHHHHCCCCCEECCCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]