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The map label for this gene is glnS [H]

Identifier: 238027799

GI number: 238027799

Start: 2424693

End: 2426402

Strand: Direct

Name: glnS [H]

Synonym: bglu_1g22250

Alternate gene names: 238027799

Gene position: 2424693-2426402 (Clockwise)

Preceding gene: 238027797

Following gene: 238027802

Centisome position: 62.07

GC content: 65.96

Gene sequence:

>1710_bases
ATGAGCACCGAACGCAACGACGCCCCCGCGGCATCCAACTTCATTCGCAACATCATCGACGACGACAACGACTCGGGCAA
ATGGGGCGGGCGCGTCGAGACGCGCTTCCCGCCCGAGCCGAACGGCTACCTGCACATCGGCCATGCCAAGAGCATCTGCC
TGAATTTCGGCGTGGCGCGCGATTACGGCGGCGTCTGCCACCTGCGCTTCGACGACACGAACCCCGAGAAGGAAAGCGTC
GAGTACGTGAACTCGATCATCGACGCCGTGAAATGGCTCGGCTTCGACTGGCACAAGGACGGCGCCGATCATCAGTATTT
CGCGAGCGATTACTACGACAAGCTCTACCAGTTCGCCGAGCTGCTGATCGAGCGCGGCCGCGCCTACGTGGACAGCCAGA
GCGCCGACGAGATGCGCGCCAACCGCGGCTCGCTGACCGAGCCGGGCAAGCCCTCGCCGTTCCGCGATCGCAGCGTGGAG
GAAAACCTCGATCTGTTCCGCCGCATGAAGGCCGGCGAATTCGCCGAAGGCGAGCACGTGCTGCGCGCGAAGATCGACAT
GGCCTCGCCGAACTTCAACATGCGCGACCCGGTGCTGTACCGGATCCGCTTCGCGCATCACTACCGCACGGGCGACGCGT
GGTGCATCTACCCGATGTACGACTACACGCACTGCATTTCGGACGCGCTCGAGAACATCACGCACTCGCTCTGCACGCTC
GAGTTCGAGGATCACCGCCCGCTCTACGACTGGGTGCTCAACGAGCTGGCCGATGCCGGCGTGTTCACGCGGCCGCTGCC
GCAGCAGATCGAGTTCTCGCGCCTGAACCTGACCTATGCGATCACCAGCAAGCGCAAGCTGCTGCAACTCGTGACCGAGA
ACCATGTGGACGGCTGGGACGATCCGCGCATGCCCACCATCGTCGGCATCCGCCGCCGCGGCTTCACGCCCGAGAGCCTG
CAGCTGTTCTGCGAGCGCATCGGCGTGACCAAGGTCGATTCGTGGATCGACATGAGCGTGCTCGAGGGCGCGCTGCGCGA
CGATCTCGACGAGAAGGCGCCGCGCACCGCCGCCGTGCTCGATCCGCTCAAGCTCGTGATCGACAACTACCCGGAAGGCC
AGAGCGAGGCCTGCACCGCGCCGGTCCATCCGCACCACCCGGAGCGCGGCCTGCGCACGTTCCCGATCTCGCGCGAGCTG
TGGATCGAGCGCGACGACTTCCAGGAGGCGCCGGCGAAGGGTTACTTCCGCCTGTACCCGGGCAACAAGGTGCGGCTGCG
CTACGGCTACGTGGTCGAGTGCACGGGCTTCGACAAGGACGAGCAGGGCAACGTCACCGCAGTCCACTGCAACTACTTCC
CCGACAGCAAGTCGGGCACGGAAGGCGCGAACCACTACAAGGTCAAGGGCAACATCCACTGGGTCAGCGCCGCGCACGCG
GTGGCGGCCGAGGTGCGCATCTACGACCGCCTGTTCCGCGAGCCGCATCCCGACGCGGGCGGGCGCAACTACCTGGAAGC
GCTGAACCCCGATTCGAAGAAGATCGTGAACGCCTACCTCGAACCGGGCGCGGAGCACGCCGAGGCCGAGGCGCGCTACC
AGTTCGAGCGCCACGGCTACTTCGTGGCCGACCGCCTCGACACGCGGCCGGGCAAGCCGGTGTTCAACCGGATCGTGCCG
CTGCGCGACAGCTGGGGCAGCGGCAAGTAA

Upstream 100 bases:

>100_bases
GCGCCCGGCCGAGGGGGCCTCTCACCGCCGGTCCGGCTCAGGTAGAATCGATGGTTTCAGGCCGCGCGACCGGCGCGCGC
CCACTTCTTCCAGTTCCCGC

Downstream 100 bases:

>100_bases
GCGGCCCGCGCGCCATGAAAAATCCCCGGTCCAGCCGGGGATTTTTCATGTGGCCCGTCTCATTCGCCTGCGCGGTGGGG
TCAGCCCGGCAACTGGCGAT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 569; Mature: 568

Protein sequence:

>569_residues
MSTERNDAPAASNFIRNIIDDDNDSGKWGGRVETRFPPEPNGYLHIGHAKSICLNFGVARDYGGVCHLRFDDTNPEKESV
EYVNSIIDAVKWLGFDWHKDGADHQYFASDYYDKLYQFAELLIERGRAYVDSQSADEMRANRGSLTEPGKPSPFRDRSVE
ENLDLFRRMKAGEFAEGEHVLRAKIDMASPNFNMRDPVLYRIRFAHHYRTGDAWCIYPMYDYTHCISDALENITHSLCTL
EFEDHRPLYDWVLNELADAGVFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTENHVDGWDDPRMPTIVGIRRRGFTPESL
QLFCERIGVTKVDSWIDMSVLEGALRDDLDEKAPRTAAVLDPLKLVIDNYPEGQSEACTAPVHPHHPERGLRTFPISREL
WIERDDFQEAPAKGYFRLYPGNKVRLRYGYVVECTGFDKDEQGNVTAVHCNYFPDSKSGTEGANHYKVKGNIHWVSAAHA
VAAEVRIYDRLFREPHPDAGGRNYLEALNPDSKKIVNAYLEPGAEHAEAEARYQFERHGYFVADRLDTRPGKPVFNRIVP
LRDSWGSGK

Sequences:

>Translated_569_residues
MSTERNDAPAASNFIRNIIDDDNDSGKWGGRVETRFPPEPNGYLHIGHAKSICLNFGVARDYGGVCHLRFDDTNPEKESV
EYVNSIIDAVKWLGFDWHKDGADHQYFASDYYDKLYQFAELLIERGRAYVDSQSADEMRANRGSLTEPGKPSPFRDRSVE
ENLDLFRRMKAGEFAEGEHVLRAKIDMASPNFNMRDPVLYRIRFAHHYRTGDAWCIYPMYDYTHCISDALENITHSLCTL
EFEDHRPLYDWVLNELADAGVFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTENHVDGWDDPRMPTIVGIRRRGFTPESL
QLFCERIGVTKVDSWIDMSVLEGALRDDLDEKAPRTAAVLDPLKLVIDNYPEGQSEACTAPVHPHHPERGLRTFPISREL
WIERDDFQEAPAKGYFRLYPGNKVRLRYGYVVECTGFDKDEQGNVTAVHCNYFPDSKSGTEGANHYKVKGNIHWVSAAHA
VAAEVRIYDRLFREPHPDAGGRNYLEALNPDSKKIVNAYLEPGAEHAEAEARYQFERHGYFVADRLDTRPGKPVFNRIVP
LRDSWGSGK
>Mature_568_residues
STERNDAPAASNFIRNIIDDDNDSGKWGGRVETRFPPEPNGYLHIGHAKSICLNFGVARDYGGVCHLRFDDTNPEKESVE
YVNSIIDAVKWLGFDWHKDGADHQYFASDYYDKLYQFAELLIERGRAYVDSQSADEMRANRGSLTEPGKPSPFRDRSVEE
NLDLFRRMKAGEFAEGEHVLRAKIDMASPNFNMRDPVLYRIRFAHHYRTGDAWCIYPMYDYTHCISDALENITHSLCTLE
FEDHRPLYDWVLNELADAGVFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTENHVDGWDDPRMPTIVGIRRRGFTPESLQ
LFCERIGVTKVDSWIDMSVLEGALRDDLDEKAPRTAAVLDPLKLVIDNYPEGQSEACTAPVHPHHPERGLRTFPISRELW
IERDDFQEAPAKGYFRLYPGNKVRLRYGYVVECTGFDKDEQGNVTAVHCNYFPDSKSGTEGANHYKVKGNIHWVSAAHAV
AAEVRIYDRLFREPHPDAGGRNYLEALNPDSKKIVNAYLEPGAEHAEAEARYQFERHGYFVADRLDTRPGKPVFNRIVPL
RDSWGSGK

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=545, Percent_Identity=44.4036697247706, Blast_Score=428, Evalue=1e-120,
Organism=Homo sapiens, GI62241042, Length=528, Percent_Identity=33.3333333333333, Blast_Score=258, Evalue=1e-68,
Organism=Escherichia coli, GI1786895, Length=556, Percent_Identity=57.7338129496403, Blast_Score=643, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=127, Percent_Identity=29.1338582677165, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17543332, Length=553, Percent_Identity=42.8571428571429, Blast_Score=411, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI17511007, Length=526, Percent_Identity=29.6577946768061, Blast_Score=218, Evalue=5e-57,
Organism=Saccharomyces cerevisiae, GI6324742, Length=577, Percent_Identity=40.9012131715771, Blast_Score=410, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321192, Length=536, Percent_Identity=32.8358208955224, Blast_Score=260, Evalue=4e-70,
Organism=Drosophila melanogaster, GI17864488, Length=548, Percent_Identity=41.6058394160584, Blast_Score=417, Evalue=1e-117,
Organism=Drosophila melanogaster, GI24649466, Length=419, Percent_Identity=36.9928400954654, Blast_Score=242, Evalue=4e-64,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 65186; Mature: 65055

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTERNDAPAASNFIRNIIDDDNDSGKWGGRVETRFPPEPNGYLHIGHAKSICLNFGVAR
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCEEEECCHHHHHHHCCCCC
DYGGVCHLRFDDTNPEKESVEYVNSIIDAVKWLGFDWHKDGADHQYFASDYYDKLYQFAE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LLIERGRAYVDSQSADEMRANRGSLTEPGKPSPFRDRSVEENLDLFRRMKAGEFAEGEHV
HHHHCCCCEECCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEE
LRAKIDMASPNFNMRDPVLYRIRFAHHYRTGDAWCIYPMYDYTHCISDALENITHSLCTL
EEEEEEECCCCCCCCCCEEEEEEEEHEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEE
EFEDHRPLYDWVLNELADAGVFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTENHVDGWD
EECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCCCCC
DPRMPTIVGIRRRGFTPESLQLFCERIGVTKVDSWIDMSVLEGALRDDLDEKAPRTAAVL
CCCCCCEEEHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHH
DPLKLVIDNYPEGQSEACTAPVHPHHPERGLRTFPISRELWIERDDFQEAPAKGYFRLYP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHEEECCCHHCCCCCCEEEECC
GNKVRLRYGYVVECTGFDKDEQGNVTAVHCNYFPDSKSGTEGANHYKVKGNIHWVSAAHA
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCEEEEEHHHH
VAAEVRIYDRLFREPHPDAGGRNYLEALNPDSKKIVNAYLEPGAEHAEAEARYQFERHGY
HHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCE
FVADRLDTRPGKPVFNRIVPLRDSWGSGK
EEEECCCCCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
STERNDAPAASNFIRNIIDDDNDSGKWGGRVETRFPPEPNGYLHIGHAKSICLNFGVAR
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCEECCCCCCCCCCEEEECCHHHHHHHCCCCC
DYGGVCHLRFDDTNPEKESVEYVNSIIDAVKWLGFDWHKDGADHQYFASDYYDKLYQFAE
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
LLIERGRAYVDSQSADEMRANRGSLTEPGKPSPFRDRSVEENLDLFRRMKAGEFAEGEHV
HHHHCCCCEECCCCHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEE
LRAKIDMASPNFNMRDPVLYRIRFAHHYRTGDAWCIYPMYDYTHCISDALENITHSLCTL
EEEEEEECCCCCCCCCCEEEEEEEEHEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEE
EFEDHRPLYDWVLNELADAGVFTRPLPQQIEFSRLNLTYAITSKRKLLQLVTENHVDGWD
EECCCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCHHHHHHHHHHCCCCCCC
DPRMPTIVGIRRRGFTPESLQLFCERIGVTKVDSWIDMSVLEGALRDDLDEKAPRTAAVL
CCCCCCEEEHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHH
DPLKLVIDNYPEGQSEACTAPVHPHHPERGLRTFPISRELWIERDDFQEAPAKGYFRLYP
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCHHHEEECCCHHCCCCCCEEEECC
GNKVRLRYGYVVECTGFDKDEQGNVTAVHCNYFPDSKSGTEGANHYKVKGNIHWVSAAHA
CCEEEEEEEEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEECCEEEEEHHHH
VAAEVRIYDRLFREPHPDAGGRNYLEALNPDSKKIVNAYLEPGAEHAEAEARYQFERHGY
HHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCE
FVADRLDTRPGKPVFNRIVPLRDSWGSGK
EEEECCCCCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA