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The map label for this gene is murR [H]

Identifier: 238027776

GI number: 238027776

Start: 2396940

End: 2397818

Strand: Reverse

Name: murR [H]

Synonym: bglu_1g22000

Alternate gene names: 238027776

Gene position: 2397818-2396940 (Counterclockwise)

Preceding gene: 238027784

Following gene: 238027775

Centisome position: 61.38

GC content: 67.69

Gene sequence:

>879_bases
ATGGACGAGACACCGCATTCCGAGACGCCCGTCGACGCGCTGCTGCAGCGCATCACCGAGGCTTACGACGCGCTGCCGAG
GCAGTTGAAGCGCATCGCCTCGTACATCGACGAGCATCGCGCCAACGTGATGATGGATCGCACCAGTGACATCGCCGAGC
GCTGCGGCGTGCATCCGTCGGCGGTGGTGCGCTTCGCGCAGCGTTTCGGCTTCTCGGGGTTCTCGGATCTGCAGGCGGTG
TTTCGCGACGCCTACACGGGCCAGAATCCGGCCGGGCAGAGCTACCGGCAGCGGATTCGTTCGCTGATCGACCAGCGGCG
CGGCGCGCTGTCGGTGCCGGCCGTCGCGCACCAGTTCATCGAGGCCTCGCGCGCCGGTCTCGACGAGCTGGCGGCGGGGC
TCGACGACACGCAGTTCGACGCGGCCGTGTCGATGCTCGAGAAGGCCGAGAACATCTACGTGATCGGCGTGCGCCGGTCG
TTTCCGGTGGCGAGCTACATCGTCTACGCGCTGCAGCACACGGCGCGGCGCGTGCACCTGGTGTCGGGGCTCGGCGGCAT
GTACCGCGAGCAGATCCGCAGCGTCGGGCGCGGCGACGTGGTGGTCGCGATCAGCTTCGCGCCCTACGGCAAGGAGACCC
GGTACTGCCTGCGCGCCGCGCGCCTGAACCATGCGAACACGCTCGTGATCACGGACAGCCGGCTTTCGCCGCTGGTCCGC
GAGGCGAGCGCGCATCTGCTCGTGAAGGAGGGCAGCGCGTTCGCGTTCCGCTCGCTCACGAGCACCATCTGCCTGTGCCA
GGCGCTGTTCATCGCGCTCGCGTACCGGCTCGAACTGAACGTGGAAGAAGTGAAGGACACTGGAGGATACGATGACTGA

Upstream 100 bases:

>100_bases
TTCCATTTCGACGGCGAACTGCCTATACTCGGCTCACGACATCGGCATGGCGCCCGGTGCCGCGCGGGCCTCGCGCGGCG
GGGCCGCGCAGCCGCACACC

Downstream 100 bases:

>100_bases
AGCAGTGCCGACGATCGACGTCGCCGTGTTCGGCGCCGGGCGCATCGGCCGCATCCATGCGGCGAATCTCGCGCGCCAGC
CGGGCGTGCGGCTCAAGTAC

Product: SIS domain-containing protein

Products: NA

Alternate protein names: MurPQ operon repressor [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MDETPHSETPVDALLQRITEAYDALPRQLKRIASYIDEHRANVMMDRTSDIAERCGVHPSAVVRFAQRFGFSGFSDLQAV
FRDAYTGQNPAGQSYRQRIRSLIDQRRGALSVPAVAHQFIEASRAGLDELAAGLDDTQFDAAVSMLEKAENIYVIGVRRS
FPVASYIVYALQHTARRVHLVSGLGGMYREQIRSVGRGDVVVAISFAPYGKETRYCLRAARLNHANTLVITDSRLSPLVR
EASAHLLVKEGSAFAFRSLTSTICLCQALFIALAYRLELNVEEVKDTGGYDD

Sequences:

>Translated_292_residues
MDETPHSETPVDALLQRITEAYDALPRQLKRIASYIDEHRANVMMDRTSDIAERCGVHPSAVVRFAQRFGFSGFSDLQAV
FRDAYTGQNPAGQSYRQRIRSLIDQRRGALSVPAVAHQFIEASRAGLDELAAGLDDTQFDAAVSMLEKAENIYVIGVRRS
FPVASYIVYALQHTARRVHLVSGLGGMYREQIRSVGRGDVVVAISFAPYGKETRYCLRAARLNHANTLVITDSRLSPLVR
EASAHLLVKEGSAFAFRSLTSTICLCQALFIALAYRLELNVEEVKDTGGYDD
>Mature_292_residues
MDETPHSETPVDALLQRITEAYDALPRQLKRIASYIDEHRANVMMDRTSDIAERCGVHPSAVVRFAQRFGFSGFSDLQAV
FRDAYTGQNPAGQSYRQRIRSLIDQRRGALSVPAVAHQFIEASRAGLDELAAGLDDTQFDAAVSMLEKAENIYVIGVRRS
FPVASYIVYALQHTARRVHLVSGLGGMYREQIRSVGRGDVVVAISFAPYGKETRYCLRAARLNHANTLVITDSRLSPLVR
EASAHLLVKEGSAFAFRSLTSTICLCQALFIALAYRLELNVEEVKDTGGYDD

Specific function: Represses the expression of the murPQ operon involved in the uptake and degradation of N-acetylmuramic acid (MurNAc). Binds to two adjacent inverted repeats within the operator region. MurNAc 6-phosphate, the substrate of murQ, is the specific inducer tha

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788767, Length=234, Percent_Identity=23.5042735042735, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022821
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 32388; Mature: 32388

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDETPHSETPVDALLQRITEAYDALPRQLKRIASYIDEHRANVMMDRTSDIAERCGVHPS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AVVRFAQRFGFSGFSDLQAVFRDAYTGQNPAGQSYRQRIRSLIDQRRGALSVPAVAHQFI
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EASRAGLDELAAGLDDTQFDAAVSMLEKAENIYVIGVRRSFPVASYIVYALQHTARRVHL
HHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
VSGLGGMYREQIRSVGRGDVVVAISFAPYGKETRYCLRAARLNHANTLVITDSRLSPLVR
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHH
EASAHLLVKEGSAFAFRSLTSTICLCQALFIALAYRLELNVEEVKDTGGYDD
HHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCC
>Mature Secondary Structure
MDETPHSETPVDALLQRITEAYDALPRQLKRIASYIDEHRANVMMDRTSDIAERCGVHPS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AVVRFAQRFGFSGFSDLQAVFRDAYTGQNPAGQSYRQRIRSLIDQRRGALSVPAVAHQFI
HHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHH
EASRAGLDELAAGLDDTQFDAAVSMLEKAENIYVIGVRRSFPVASYIVYALQHTARRVHL
HHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHH
VSGLGGMYREQIRSVGRGDVVVAISFAPYGKETRYCLRAARLNHANTLVITDSRLSPLVR
HHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCEEEEECCHHHHHHH
EASAHLLVKEGSAFAFRSLTSTICLCQALFIALAYRLELNVEEVKDTGGYDD
HHHHHEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA