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The map label for this gene is tcp [H]

Identifier: 238027435

GI number: 238027435

Start: 2010845

End: 2012485

Strand: Direct

Name: tcp [H]

Synonym: bglu_1g18380

Alternate gene names: 238027435

Gene position: 2010845-2012485 (Clockwise)

Preceding gene: 238027434

Following gene: 238027436

Centisome position: 51.47

GC content: 71.12

Gene sequence:

>1641_bases
ATGAAAATTCTGCGGCTGAGCATCAAGGCCAAGCTACTTGGTGCTTTCGGCTTGCTGGCGGCGGTCGTCATCGGCATTTC
CGCGTTCGCGCTGAATGCGCTGTCGGACACCAACCATGCGTTCGCCAGCTATACCCAGGGCATCAATGCCCGCGCCAACG
TGGCCGAGGAAGTGCGCACGGCGGTGGACCGCCGCGCAGTCGCGGCGCGCAATCTGGTGCTAGTGACCCGGCCCGAGGAT
GTCGCGGTGGAAAAGGCCGAGGTCGAGCGCGCGCACGCGGACGTGCGGCAGCGGCTCGCGCAGTTGCAGTCGATGCTGGC
CGCCGCCCCCGACGCCACCGACCACGCCCGCGAGCTGGCCGCCGCCATCGCCGAGGTGGAGCGCCGCTACGGCCCAGTCG
CGCAGCGGATCGTCGATCTGGCGCTGCAGGGCAAGCGCGACGCGGCGACGCTCGCCATCGACGACGAGTGCCGCCCGCTG
CTGGTCGAACTGGTGCGCGCCACCGACGCCTACGCGGCCTATACGCGCGAGCGCGAGGCCGAGCTCGCGCAGGCCGGCGC
CGAGCGCTACGCGAGCATACGCAACCTGATGGCCGTGATCAGCGCGGCGGCGGTGCTGCTGGCGATCGTCGCCGGGCTCT
GGCTCACGCGCGCGATCACGCGGCCGCTGTCCGATGCCGTGCGCGTGGCGCGTACCGTCGCCGACGGCGACCTGACGAGC
CACATCCAGGTGCGCGGCCACGACGAGACGCGCGACCTGCTCGACGCGCTCGACACCATGAACACGCGGCTCGCCGGCAT
CGTCAGCCGCGTGCGCGAGGGCAGCTCGAGCATCGCCTCGGCGGTCGGCGAGATCGCGGCGGGCAACATCGACCTGAGCC
AGCGCACCGAGGAACAGGCCGCCTCGCTGGAGGAAACGGCCGCCACCATGGAACAGTTCACCTCCACGGTCCGGCTCAAC
GCGGAGAACGCGCGCCAGGCCAGCGAACTCGCCAGCAGCGCCTCGGAGGTCGCGCAGCGCGGCAGCCACGCGGTGGGCCG
CGTGGTCCGCACCATGAACGACATCGGCGAACGCTCGTCGAAGATCGCCGACATCACCGGCATCATCGAGGGCATCGCGT
TCCAGACCAACATCCTCGCGCTGAACGCGGCGGTGGAAGCGGCGCGCGCCGGCGAAGAGGGGCGCGGCTTCGCGGTGGTG
GCCAGCGAAGTGCGCTCGCTCGCCCAACGCTCGTCGGTGGCGGCCAAGGAAATCAAGGATCTGATCACCACCTCGGTGCA
GACGGTGCACGACGGCGCCGCGGTGGCCGACGAGGCCGGCCGCACCATGACCGAGGTCACGCAGGCGGTGGCGCGCGTGA
CCGACATCATGGAGCAGATCGCGTCGGCCTCGACCGAGCAGAGCCGCGGCATCGAGCAGGTGAATCTGGCGATCACCCAA
ATGGACAACACCACCCAGCAGAACGCGGCGCTCGTCGAGCAGGCCGCGGCCGCGTCGAAATCGCTGGAAATGCAGGGGCG
GCAGCTCGACGAGACGGTGGCGCGCTTTCGCCTCGGCGCCACCCGGCCGGATGCGCCGGCCGCGAGCAGCGTGCCCGAGC
GCCACGCGGGCCACGCCGACTGGCGCCTGGCGACGGCCTGA

Upstream 100 bases:

>100_bases
TAAAGAAAAAAAAGAATGGCCCGTTAACGCAGCTACAACGAGGGACGTCGCACCGATTTTCGTCTCAAACCCTAATTTCA
AGAAGAGAGAGAGGCCAATC

Downstream 100 bases:

>100_bases
ACGAGGTGCCGCGCCTGCCGCGGCCGCCGGGCTGGCGCGCCGCGCCGTGGCGGGCGGCGGCACGGCAGCGCGGCGGCGGA
TGGCGGCCCGGCAGCGCCGG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 546; Mature: 546

Protein sequence:

>546_residues
MKILRLSIKAKLLGAFGLLAAVVIGISAFALNALSDTNHAFASYTQGINARANVAEEVRTAVDRRAVAARNLVLVTRPED
VAVEKAEVERAHADVRQRLAQLQSMLAAAPDATDHARELAAAIAEVERRYGPVAQRIVDLALQGKRDAATLAIDDECRPL
LVELVRATDAYAAYTREREAELAQAGAERYASIRNLMAVISAAAVLLAIVAGLWLTRAITRPLSDAVRVARTVADGDLTS
HIQVRGHDETRDLLDALDTMNTRLAGIVSRVREGSSSIASAVGEIAAGNIDLSQRTEEQAASLEETAATMEQFTSTVRLN
AENARQASELASSASEVAQRGSHAVGRVVRTMNDIGERSSKIADITGIIEGIAFQTNILALNAAVEAARAGEEGRGFAVV
ASEVRSLAQRSSVAAKEIKDLITTSVQTVHDGAAVADEAGRTMTEVTQAVARVTDIMEQIASASTEQSRGIEQVNLAITQ
MDNTTQQNAALVEQAAAASKSLEMQGRQLDETVARFRLGATRPDAPAASSVPERHAGHADWRLATA

Sequences:

>Translated_546_residues
MKILRLSIKAKLLGAFGLLAAVVIGISAFALNALSDTNHAFASYTQGINARANVAEEVRTAVDRRAVAARNLVLVTRPED
VAVEKAEVERAHADVRQRLAQLQSMLAAAPDATDHARELAAAIAEVERRYGPVAQRIVDLALQGKRDAATLAIDDECRPL
LVELVRATDAYAAYTREREAELAQAGAERYASIRNLMAVISAAAVLLAIVAGLWLTRAITRPLSDAVRVARTVADGDLTS
HIQVRGHDETRDLLDALDTMNTRLAGIVSRVREGSSSIASAVGEIAAGNIDLSQRTEEQAASLEETAATMEQFTSTVRLN
AENARQASELASSASEVAQRGSHAVGRVVRTMNDIGERSSKIADITGIIEGIAFQTNILALNAAVEAARAGEEGRGFAVV
ASEVRSLAQRSSVAAKEIKDLITTSVQTVHDGAAVADEAGRTMTEVTQAVARVTDIMEQIASASTEQSRGIEQVNLAITQ
MDNTTQQNAALVEQAAAASKSLEMQGRQLDETVARFRLGATRPDAPAASSVPERHAGHADWRLATA
>Mature_546_residues
MKILRLSIKAKLLGAFGLLAAVVIGISAFALNALSDTNHAFASYTQGINARANVAEEVRTAVDRRAVAARNLVLVTRPED
VAVEKAEVERAHADVRQRLAQLQSMLAAAPDATDHARELAAAIAEVERRYGPVAQRIVDLALQGKRDAATLAIDDECRPL
LVELVRATDAYAAYTREREAELAQAGAERYASIRNLMAVISAAAVLLAIVAGLWLTRAITRPLSDAVRVARTVADGDLTS
HIQVRGHDETRDLLDALDTMNTRLAGIVSRVREGSSSIASAVGEIAAGNIDLSQRTEEQAASLEETAATMEQFTSTVRLN
AENARQASELASSASEVAQRGSHAVGRVVRTMNDIGERSSKIADITGIIEGIAFQTNILALNAAVEAARAGEEGRGFAVV
ASEVRSLAQRSSVAAKEIKDLITTSVQTVHDGAAVADEAGRTMTEVTQAVARVTDIMEQIASASTEQSRGIEQVNLAITQ
MDNTTQQNAALVEQAAAASKSLEMQGRQLDETVARFRLGATRPDAPAASSVPERHAGHADWRLATA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=351, Percent_Identity=54.4159544159544, Blast_Score=305, Evalue=5e-84,
Organism=Escherichia coli, GI1788195, Length=327, Percent_Identity=54.434250764526, Blast_Score=302, Evalue=5e-83,
Organism=Escherichia coli, GI1788194, Length=339, Percent_Identity=51.622418879056, Blast_Score=291, Evalue=6e-80,
Organism=Escherichia coli, GI1787690, Length=315, Percent_Identity=53.015873015873, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI1789453, Length=315, Percent_Identity=37.1428571428571, Blast_Score=187, Evalue=1e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57953; Mature: 57953

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILRLSIKAKLLGAFGLLAAVVIGISAFALNALSDTNHAFASYTQGINARANVAEEVRT
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHH
AVDRRAVAARNLVLVTRPEDVAVEKAEVERAHADVRQRLAQLQSMLAAAPDATDHARELA
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAIAEVERRYGPVAQRIVDLALQGKRDAATLAIDDECRPLLVELVRATDAYAAYTREREA
HHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ELAQAGAERYASIRNLMAVISAAAVLLAIVAGLWLTRAITRPLSDAVRVARTVADGDLTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HIQVRGHDETRDLLDALDTMNTRLAGIVSRVREGSSSIASAVGEIAAGNIDLSQRTEEQA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHH
ASLEETAATMEQFTSTVRLNAENARQASELASSASEVAQRGSHAVGRVVRTMNDIGERSS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KIADITGIIEGIAFQTNILALNAAVEAARAGEEGRGFAVVASEVRSLAQRSSVAAKEIKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LITTSVQTVHDGAAVADEAGRTMTEVTQAVARVTDIMEQIASASTEQSRGIEQVNLAITQ
HHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHH
MDNTTQQNAALVEQAAAASKSLEMQGRQLDETVARFRLGATRPDAPAASSVPERHAGHAD
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCC
WRLATA
CEECCC
>Mature Secondary Structure
MKILRLSIKAKLLGAFGLLAAVVIGISAFALNALSDTNHAFASYTQGINARANVAEEVRT
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHHH
AVDRRAVAARNLVLVTRPEDVAVEKAEVERAHADVRQRLAQLQSMLAAAPDATDHARELA
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AAIAEVERRYGPVAQRIVDLALQGKRDAATLAIDDECRPLLVELVRATDAYAAYTREREA
HHHHHHHHHHCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
ELAQAGAERYASIRNLMAVISAAAVLLAIVAGLWLTRAITRPLSDAVRVARTVADGDLTS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
HIQVRGHDETRDLLDALDTMNTRLAGIVSRVREGSSSIASAVGEIAAGNIDLSQRTEEQA
EEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHH
ASLEETAATMEQFTSTVRLNAENARQASELASSASEVAQRGSHAVGRVVRTMNDIGERSS
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
KIADITGIIEGIAFQTNILALNAAVEAARAGEEGRGFAVVASEVRSLAQRSSVAAKEIKD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LITTSVQTVHDGAAVADEAGRTMTEVTQAVARVTDIMEQIASASTEQSRGIEQVNLAITQ
HHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHH
MDNTTQQNAALVEQAAAASKSLEMQGRQLDETVARFRLGATRPDAPAASSVPERHAGHAD
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCC
WRLATA
CEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]