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The map label for this gene is livH [H]

Identifier: 238027295

GI number: 238027295

Start: 1851782

End: 1852696

Strand: Reverse

Name: livH [H]

Synonym: bglu_1g16820

Alternate gene names: 238027295

Gene position: 1852696-1851782 (Counterclockwise)

Preceding gene: 238027296

Following gene: 238027294

Centisome position: 47.43

GC content: 76.5

Gene sequence:

>915_bases
ATGCTCGCGCTGCTGTTCGACGCGCTCGCGCTCGGCGCCGCCTATGCCCTGCTGGCCAGCGGCTTCACGCTGGTGTTCGG
GGTGCTCGGGCGCGTCAACCTCGCCTATGGCGCGACGGTGATGCTCGGCCTCTACGTGGCGATCCGCGCCACCGCCGCGC
TGCCGCCCGCCGCGGCGTTCGCGCTCGCGCCGCTGGTCGCCGTGGCCGTGACGGTCCTCGCCAACCGCTACGTCGACCTG
CTCTGCTTCGCGCCGCACCGCGACGGCTCGGGCGTGACCGCGATGGCGGCGAGCTTCGCGGTCTGGATGCAGATCGAGGA
AGCCGGCGCGCATCTGCTGAGCGCGCATGCCAACCCGTGGCCCTCGCCGTTCGCGAGCCTGCCCGCCAGCTGGCAGGCGC
TGCCGCTGCGGGCCGAGCATGGGCTCGCGCTCGGCTGCGCGGCGCTCGTCACGTTCGGCTGCCGGCGCCTGATCGAGCGC
ACGCGCTTCGGTCTCGCGGTGCGCGCGATCGTCGACGACCGCGCGGCCGCGACTCTCGCGGGCGTGGACGTGCGGCGCGT
CTCGGCGCGCGTGGTGGCGCTCTCGGCCGCGCTCGGCGCGCTGGCGGGCTGCCTGATCGCAGGCATCCACGGCCAGGTCA
GCGCGATGTTCGCGATGTGGGCGACGCTCAAGGGGCTCGCGGCGGCCGTGATCGGCGGCTTCGGCTCGCTGCCGGGCGCG
GTGGCGGGCGGGCTCGCGCTGGGGTTGATCGAGGCGGCCCTGCAGGCCCTGTTCGGCGCGCAGGCGCGCGACCTCGGCGG
CGACCTGCTGCTGTTCGCGGCACTCTGCGCCTGGCCGGGCGGCCTCGCCTCGCTGCTGCCGCGCAGGCTCGGGCGCGGCG
CTGCCGCGCCGGCCGACGGAGCCGCCCGCCCATGA

Upstream 100 bases:

>100_bases
GTGCAGCGCGCCTGGCTCGGCGCCGCTGCGCCGGCCGCGGATGCGGCCGGGCCGGGCCGCGGGAACGCCCTGCCCGCCCG
CCCCCGCGGGCGCGCCTGAG

Downstream 100 bases:

>100_bases
CGCTCGTCACCAACCTCGGCCTGCTGTCGTTTCTCGCGCTGTCGGCCTACGTGCTGGCGATTGCCGGCGATTTCTCGTTC
GGCCAGCAGGCGCTGTTCGC

Product: Branched-chain amino acid ABC-type transport system, permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein H [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MLALLFDALALGAAYALLASGFTLVFGVLGRVNLAYGATVMLGLYVAIRATAALPPAAAFALAPLVAVAVTVLANRYVDL
LCFAPHRDGSGVTAMAASFAVWMQIEEAGAHLLSAHANPWPSPFASLPASWQALPLRAEHGLALGCAALVTFGCRRLIER
TRFGLAVRAIVDDRAAATLAGVDVRRVSARVVALSAALGALAGCLIAGIHGQVSAMFAMWATLKGLAAAVIGGFGSLPGA
VAGGLALGLIEAALQALFGAQARDLGGDLLLFAALCAWPGGLASLLPRRLGRGAAAPADGAARP

Sequences:

>Translated_304_residues
MLALLFDALALGAAYALLASGFTLVFGVLGRVNLAYGATVMLGLYVAIRATAALPPAAAFALAPLVAVAVTVLANRYVDL
LCFAPHRDGSGVTAMAASFAVWMQIEEAGAHLLSAHANPWPSPFASLPASWQALPLRAEHGLALGCAALVTFGCRRLIER
TRFGLAVRAIVDDRAAATLAGVDVRRVSARVVALSAALGALAGCLIAGIHGQVSAMFAMWATLKGLAAAVIGGFGSLPGA
VAGGLALGLIEAALQALFGAQARDLGGDLLLFAALCAWPGGLASLLPRRLGRGAAAPADGAARP
>Mature_304_residues
MLALLFDALALGAAYALLASGFTLVFGVLGRVNLAYGATVMLGLYVAIRATAALPPAAAFALAPLVAVAVTVLANRYVDL
LCFAPHRDGSGVTAMAASFAVWMQIEEAGAHLLSAHANPWPSPFASLPASWQALPLRAEHGLALGCAALVTFGCRRLIER
TRFGLAVRAIVDDRAAATLAGVDVRRVSARVVALSAALGALAGCLIAGIHGQVSAMFAMWATLKGLAAAVIGGFGSLPGA
VAGGLALGLIEAALQALFGAQARDLGGDLLLFAALCAWPGGLASLLPRRLGRGAAAPADGAARP

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=291, Percent_Identity=29.553264604811, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 30621; Mature: 30621

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLALLFDALALGAAYALLASGFTLVFGVLGRVNLAYGATVMLGLYVAIRATAALPPAAAF
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALAPLVAVAVTVLANRYVDLLCFAPHRDGSGVTAMAASFAVWMQIEEAGAHLLSAHANPW
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PSPFASLPASWQALPLRAEHGLALGCAALVTFGCRRLIERTRFGLAVRAIVDDRAAATLA
CCHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVDVRRVSARVVALSAALGALAGCLIAGIHGQVSAMFAMWATLKGLAAAVIGGFGSLPGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
VAGGLALGLIEAALQALFGAQARDLGGDLLLFAALCAWPGGLASLLPRRLGRGAAAPADG
HHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
AARP
CCCC
>Mature Secondary Structure
MLALLFDALALGAAYALLASGFTLVFGVLGRVNLAYGATVMLGLYVAIRATAALPPAAAF
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
ALAPLVAVAVTVLANRYVDLLCFAPHRDGSGVTAMAASFAVWMQIEEAGAHLLSAHANPW
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PSPFASLPASWQALPLRAEHGLALGCAALVTFGCRRLIERTRFGLAVRAIVDDRAAATLA
CCHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVDVRRVSARVVALSAALGALAGCLIAGIHGQVSAMFAMWATLKGLAAAVIGGFGSLPGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
VAGGLALGLIEAALQALFGAQARDLGGDLLLFAALCAWPGGLASLLPRRLGRGAAAPADG
HHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
AARP
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]