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The map label for this gene is phbA [H]

Identifier: 238027093

GI number: 238027093

Start: 1622908

End: 1624089

Strand: Direct

Name: phbA [H]

Synonym: bglu_1g14720

Alternate gene names: 238027093

Gene position: 1622908-1624089 (Clockwise)

Preceding gene: 238027092

Following gene: 238027094

Centisome position: 41.54

GC content: 69.63

Gene sequence:

>1182_bases
ATGACTGAGGTAGTGATCGTATCGGCCGCGCGTACCGCGGTCGGCAAGTTCGGTGGGTCGCTGGCGAAGATCGCGGCGCC
CGAACTCGGCGCGGCCGTGATCCGCGCGGTGCTGGAGCGCGGCGGCGTGGCGCCCGACCAGATCAGCGAAGTGATCCTCG
GGCAGGTGCTGGCGGCCGGCTCCGGCCAGAACCCGGCGCGTCAGTCGGTGATCAAGGCCGGCCTGCCCACGGCCGTGCCG
GCGATGACCATCAACAAGGTCTGCGGCTCGGGCCTGAAGGCCGTGATGCTGGCGGCCAACGCGATCATCGCCGGCGATGC
CGAGATCGTGATCGCGGGCGGCCAGGAAAACATGAGCGCGGCGCCGCACGTGCTGCCGGGCTCGCGCGACGGCTTCCGGA
TGGGCGACGCGAAGCTGGTCGACACGATGATCGTGGACGGCCTGTGGGACGTCTACAACCAGTACCACATGGGCATCACG
GCCGAGAACGTCGCGAAGGAATATGGCATCACGCGCGAGGCGCAGGACGCGTTCGCCGCGCAGTCGCAGAACAAGGCCGA
GGCCGCCCAGAAGTCGGGCCGTTTCGACGACGAGATCGTGCCGATCGAGATCCCGCAGCGCAAGGGCGAGCCGCTGCGCT
TCGCCACCGACGAGTTCGTGCGCCACGGCGTGACGGCCGAGTCGCTGGCGGGCCTCAAGCCCGCCTTCACGAAGGAGGGC
ACGGTGACGGCCGCCAACGCCTCGGGCATCAACGACGGCGCGGCCGCGGTGCTGGTGATGTCGGCGCAGAAGGCCAAAGC
GCTCGGCCTCACGCCGCTCGCGCGTATCAAGGCCTACGCGAGCGCCGGCGTCGATCCGAAGGTGATGGGCATGGGCCCGG
TGCCGGCCTCGCGCCGCTGCCTGGAACGCGCGGGCTGGTCGGTCGACGATCTCGACCTGATGGAGATCAACGAGGCATTC
GCGGCACAGGCGCTGGCCGTGCATCAGCAGATGGGCTGGGACACCTCGAAGGTGAACGTCAACGGTGGCGCGATCGCGAT
CGGCCATCCGATCGGCGCGTCCGGCTGCCGGATTCTCGTCACGCTGCTGCACGAGATGCAAAAGCGTGACGCGAAGCGCG
GTCTCGCCTCGCTCTGTATCGGCGGCGGGATGGGGGTCGCGCTGGCGGTCGAGCGCCCCTGA

Upstream 100 bases:

>100_bases
GGGACATTGACGGATGGCGGCGGGCGGCGCACGCTCGCCGACTGCTTCCGGGGATTTTTCAACTGAGCGGGTCGCGCTTG
CCGGCCTGGAGGACAAGGAC

Downstream 100 bases:

>100_bases
CGTGCTGCCCGGCGCGGTGGGCGGCACCGGGCAACGAGGCGAAAGAGACAGACGCAAGCGCCGTCCGGCGCTTCGACAAC
GATAAATGGAGTGTTCTGTA

Product: putative acyltransferase

Products: NA

Alternate protein names: Acetoacetyl-CoA thiolase [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MTEVVIVSAARTAVGKFGGSLAKIAAPELGAAVIRAVLERGGVAPDQISEVILGQVLAAGSGQNPARQSVIKAGLPTAVP
AMTINKVCGSGLKAVMLAANAIIAGDAEIVIAGGQENMSAAPHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGIT
AENVAKEYGITREAQDAFAAQSQNKAEAAQKSGRFDDEIVPIEIPQRKGEPLRFATDEFVRHGVTAESLAGLKPAFTKEG
TVTAANASGINDGAAAVLVMSAQKAKALGLTPLARIKAYASAGVDPKVMGMGPVPASRRCLERAGWSVDDLDLMEINEAF
AAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILVTLLHEMQKRDAKRGLASLCIGGGMGVALAVERP

Sequences:

>Translated_393_residues
MTEVVIVSAARTAVGKFGGSLAKIAAPELGAAVIRAVLERGGVAPDQISEVILGQVLAAGSGQNPARQSVIKAGLPTAVP
AMTINKVCGSGLKAVMLAANAIIAGDAEIVIAGGQENMSAAPHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGIT
AENVAKEYGITREAQDAFAAQSQNKAEAAQKSGRFDDEIVPIEIPQRKGEPLRFATDEFVRHGVTAESLAGLKPAFTKEG
TVTAANASGINDGAAAVLVMSAQKAKALGLTPLARIKAYASAGVDPKVMGMGPVPASRRCLERAGWSVDDLDLMEINEAF
AAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILVTLLHEMQKRDAKRGLASLCIGGGMGVALAVERP
>Mature_392_residues
TEVVIVSAARTAVGKFGGSLAKIAAPELGAAVIRAVLERGGVAPDQISEVILGQVLAAGSGQNPARQSVIKAGLPTAVPA
MTINKVCGSGLKAVMLAANAIIAGDAEIVIAGGQENMSAAPHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITA
ENVAKEYGITREAQDAFAAQSQNKAEAAQKSGRFDDEIVPIEIPQRKGEPLRFATDEFVRHGVTAESLAGLKPAFTKEGT
VTAANASGINDGAAAVLVMSAQKAKALGLTPLARIKAYASAGVDPKVMGMGPVPASRRCLERAGWSVDDLDLMEINEAFA
AQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILVTLLHEMQKRDAKRGLASLCIGGGMGVALAVERP

Specific function: Unknown

COG id: COG0183

COG function: function code I; Acetyl-CoA acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiolase family [H]

Homologues:

Organism=Homo sapiens, GI148539872, Length=391, Percent_Identity=55.2429667519182, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI167614485, Length=390, Percent_Identity=44.6153846153846, Blast_Score=328, Evalue=4e-90,
Organism=Homo sapiens, GI4557237, Length=393, Percent_Identity=43.5114503816794, Blast_Score=322, Evalue=5e-88,
Organism=Homo sapiens, GI4501853, Length=397, Percent_Identity=41.5617128463476, Blast_Score=269, Evalue=3e-72,
Organism=Homo sapiens, GI4504327, Length=424, Percent_Identity=30.6603773584906, Blast_Score=188, Evalue=8e-48,
Organism=Homo sapiens, GI194353979, Length=394, Percent_Identity=31.4720812182741, Blast_Score=161, Evalue=9e-40,
Organism=Escherichia coli, GI87082165, Length=392, Percent_Identity=62.2448979591837, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1788554, Length=393, Percent_Identity=59.7964376590331, Blast_Score=446, Evalue=1e-126,
Organism=Escherichia coli, GI1787663, Length=404, Percent_Identity=46.2871287128713, Blast_Score=325, Evalue=3e-90,
Organism=Escherichia coli, GI48994986, Length=401, Percent_Identity=42.643391521197, Blast_Score=276, Evalue=2e-75,
Organism=Escherichia coli, GI1788683, Length=410, Percent_Identity=34.8780487804878, Blast_Score=206, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI133906874, Length=390, Percent_Identity=46.4102564102564, Blast_Score=336, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI25147385, Length=387, Percent_Identity=42.3772609819121, Blast_Score=301, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI17535921, Length=392, Percent_Identity=41.3265306122449, Blast_Score=281, Evalue=3e-76,
Organism=Caenorhabditis elegans, GI17551802, Length=428, Percent_Identity=31.5420560747664, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17535917, Length=394, Percent_Identity=32.994923857868, Blast_Score=187, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6325229, Length=393, Percent_Identity=43.2569974554707, Blast_Score=298, Evalue=1e-81,
Organism=Saccharomyces cerevisiae, GI6322031, Length=399, Percent_Identity=39.8496240601504, Blast_Score=239, Evalue=7e-64,
Organism=Drosophila melanogaster, GI24655093, Length=392, Percent_Identity=57.3979591836735, Blast_Score=453, Evalue=1e-128,
Organism=Drosophila melanogaster, GI24640423, Length=393, Percent_Identity=45.5470737913486, Blast_Score=329, Evalue=2e-90,
Organism=Drosophila melanogaster, GI17648125, Length=390, Percent_Identity=44.8717948717949, Blast_Score=316, Evalue=1e-86,
Organism=Drosophila melanogaster, GI17137578, Length=425, Percent_Identity=30.8235294117647, Blast_Score=181, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002155
- InterPro:   IPR016039
- InterPro:   IPR016038
- InterPro:   IPR020615
- InterPro:   IPR020610
- InterPro:   IPR020617
- InterPro:   IPR020613
- InterPro:   IPR020616 [H]

Pfam domain/function: PF02803 Thiolase_C; PF00108 Thiolase_N [H]

EC number: =2.3.1.9 [H]

Molecular weight: Translated: 40575; Mature: 40444

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS00098 THIOLASE_1 ; PS00737 THIOLASE_2 ; PS00099 THIOLASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVVIVSAARTAVGKFGGSLAKIAAPELGAAVIRAVLERGGVAPDQISEVILGQVLAAG
CCEEEEEEHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
SGQNPARQSVIKAGLPTAVPAMTINKVCGSGLKAVMLAANAIIAGDAEIVIAGGQENMSA
CCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHCEEEECCCEEEEECCCCCCCC
APHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDAFAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
QSQNKAEAAQKSGRFDDEIVPIEIPQRKGEPLRFATDEFVRHGVTAESLAGLKPAFTKEG
HCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEHHHHHHHCCCCHHHHCCCCCCCCCCC
TVTAANASGINDGAAAVLVMSAQKAKALGLTPLARIKAYASAGVDPKVMGMGPVPASRRC
CEEECCCCCCCCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHH
LERAGWSVDDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILV
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCHHHHHH
TLLHEMQKRDAKRGLASLCIGGGMGVALAVERP
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure 
TEVVIVSAARTAVGKFGGSLAKIAAPELGAAVIRAVLERGGVAPDQISEVILGQVLAAG
CEEEEEEHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
SGQNPARQSVIKAGLPTAVPAMTINKVCGSGLKAVMLAANAIIAGDAEIVIAGGQENMSA
CCCCHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHCEEEECCCEEEEECCCCCCCC
APHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQDAFAA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHH
QSQNKAEAAQKSGRFDDEIVPIEIPQRKGEPLRFATDEFVRHGVTAESLAGLKPAFTKEG
HCCHHHHHHHHCCCCCCCEEEEECCCCCCCCCEEHHHHHHHCCCCHHHHCCCCCCCCCCC
TVTAANASGINDGAAAVLVMSAQKAKALGLTPLARIKAYASAGVDPKVMGMGPVPASRRC
CEEECCCCCCCCCCEEEEEEEHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCCCHHHHH
LERAGWSVDDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASGCRILV
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEECCCCCCCHHHHHH
TLLHEMQKRDAKRGLASLCIGGGMGVALAVERP
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2670935; 2670936 [H]