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The map label for this gene is dnaX [H]

Identifier: 238027056

GI number: 238027056

Start: 1579718

End: 1582303

Strand: Direct

Name: dnaX [H]

Synonym: bglu_1g14350

Alternate gene names: 238027056

Gene position: 1579718-1582303 (Clockwise)

Preceding gene: 238027045

Following gene: 238027057

Centisome position: 40.44

GC content: 72.82

Gene sequence:

>2586_bases
ATGACCTATCAAGTTCTCGCACGCAAGTGGCGTCCGAAGGATTTCGCTTCGCTCGTCGGCCAGGAGCACGTCGTCAGGGC
GCTCACGCACGCGCTCGACGGCGGGCGTTTGCATCACGCCTATTTGTTTACGGGCACGCGCGGCGTCGGCAAGACCACGC
TGTCCCGGATCTTCGCCAAGGCGCTCAATTGCGAGACGGGCGTCACCTCGCAGCCGTGCGGCGTATGCCGTGCCTGCCGT
GAGATCGACGAGGGCCGTTTCGTCGACTATGTCGAAATGGATGCGGCGAGCAATCGCGGTGTCGACGAAATGGCCGCGCT
GCTCGAGCGCGCCGTGTACGCGCCCGTGGACGCGCGCTTCAAGGTCTACATGATCGACGAAGTCCACATGCTGACGAACC
ACGCCTTCAACGCGATGTTGAAGACGCTGGAAGAGCCGCCGCCGCACGTCAAGTTCATCCTTGCCACCACCGATCCGCAG
AAGATTCCCGTCACCGTCCTGTCGCGCTGCCTGCAGTTCAATCTGAAGCAGATGCCGGCCGGCCATATCGTGATGCATCT
CGAGCGCATTCTGGGCGAGGAGCGCGTCGCGTTCGAGCCACAGGCGCTGCGGCTGCTCGCGCGCGCGGCACAGGGCAGCA
TGCGCGATGCGCTGTCGTTGACCGATCAGGCGATCGCCTATTCGGCCAACGAGGTGACCGAGGCGGCCGTGTCGGGAATG
CTCGGCGCGCTGGACCAGACCTACATGGTCCGGTTGCTCGACGCGATCGCCTCGTCCGACGGCCCCGAAATCCTCGCGAT
CGCCGACGAGATGGCCTTGCGCAGCCTGTCGTTCTCGACCGCGCTGCAGGATCTGGCCGGCCTGCTGCACCGCATCGCCT
GGGCGCAGTTCGCACCGGCCTCGGTGCTCGACGAGTGGCCCGAGGCGGCCGACCTGCGCCGCTTCGCCGAGGCGCTGAGC
CCGGAGCAGGTGCAACTCTATTACCAGATCGCGACGGTCGGCCGGGGCGAACTCGGCCTCGCGCCCGACGAATATGCGGG
TTTCACGATGACGCTGCTGCGGATGCTGGCGTTCGCGCCAGCCGCGAGCGGCGGCGCGCCAGTGCCTGGCGCGGCGCCTG
CCGTGGCCGCCGGCGGCCGTCGCGCGGCCGCGCCGGTGGCGCCGGCCGGAGCCGGCGCGCGCGATGCCGCAGCGCATGCG
ATGCCACCCGTGGCCGCCGCGGCGTCTGCAAGGCCCGCGCCCGCCCCGGTGGCGCAGGCTGCGGCCGAGCCGCCGCCCGC
GGCCGTCGCCGCACCGCGCGCGGTGCCGCCAGCGGCGGCCCGCGATGTCGCGACAGCGAAGCGGCCGGCCGAGTTGCCGG
TGCGCGCCGAGCAAGCGAGGCCCGCCGAATCGGACGAGGCGGCCGCTGTCGCGCCGCGCGAATCGGCGCCGGACCTCGCG
GACGAGCCTGCCGAGTCGCCGCTTGCCTCGCAGCTCGAATCATCCGATGTCGCGCTCGGCGCCGGGCCGACGCCGCCCGC
TGAACCGGCGGCCATGCTCGAGCCGTCGCTGCGCGCCGACACGCCGCCGATGGCCGAGTCTGCGGCCGAAGCCGCGTTTG
CCGAAGACGTCTCGTCCTTGCCCGCCGCCTTGCCGCAAGCATCTCCGCCGTCGGCTGACGCCGCGCCGCTTGCCGCCGCG
CCGCGTCCCGATCGGGTCGAGCCTGCCGCGGTCCGGCCTCCGGCCGCGCCGGTTGCCGCGCCGGGCGAACGTTCCGACGC
GCTGCGCGGCGGGGGCGCCGCCGCCGCGCTCGACGTACTGCGCAACGCCGGCATGCGCGTCTCGTCCGATCGCGGCCGCG
CAGCCTCGGCCGCCAAGCCGGCGCCGGCGGCCAAGTCCGCCGCGCCGCGCGTGAACGTGCCGACCCCGCGCCCGCGCACG
GCGCAGCCGTCCCGTCCCGCCGCCGCGGCCGATCCGTCGGCGCCGCCGCCGTGGGATGACATGCCGCCCGACGATTACCT
GCCGATCTCGGCCGACGACCACTACGGGCCACCGCCCGACGACGGCTACCTTCCCGTCTTCGACAGCAGTCCCGACGACG
TGCGCGTCGCGCCGCAGCCGGCGCCCGCACCGGCTGACACCCGACCGCTGCCGCCCGCCATCGCGCTCGACGCGATCGGC
TATGCCGGCGAATGGCCGCAACTGGCCGCGACCCTGACGCTCAAGGGCGTCGCTTACCAGCTCGCGTTCAACAGCGAACT
GATTTCCGCTCAGGGCGGCGTGCTGAAGCTGGCCGTGCCGGTGCCGCAGTATGCCGACGCGGCGCAGGTGGTGAAGCTGA
AGACGGCGCTTGCCGAGGCGCTCGGCAAGCCGGTCGAGGTGGCCGTCGAGGTCGGTCCCGCGCGGCGCACGGCGGCCGCG
CTCGATGCGGTCGAGCGCGCGAAGCGCCAGCGCGAGGCCGAGCAGGAGATCGGCGCCGATCCGTTCGTCCAGCAACTGAT
TCGCGACTTCGGCGCGCGTATCGTCGAGGGCTCGGTGCGGCCCGTCGCGAGCGACGCCGCAGCGGCCGGGCCGGCCGGGC
AGTGCGGCGCGCCCACGCTGCATTGA

Upstream 100 bases:

>100_bases
GCATGACCTCACGCATCCTGCGCATGAACGACGGCCCCGGCCGGCTCGCGCCGCGCGTCCGGCTGTCGGCGGCGACCGGC
GTTACTGATACAATTTCCCG

Downstream 100 bases:

>100_bases
GCGTGCGGCGCGCGCATCCCATTCCCTAATTCCGGAACCGGCGCTAAGATCGCGCCGGTCTCACACGAACACCAAGGAGC
ACGTCCATGATGAAAGGCCA

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 861; Mature: 860

Protein sequence:

>861_residues
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR
EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPAGHIVMHLERILGEERVAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTEAAVSGM
LGALDQTYMVRLLDAIASSDGPEILAIADEMALRSLSFSTALQDLAGLLHRIAWAQFAPASVLDEWPEAADLRRFAEALS
PEQVQLYYQIATVGRGELGLAPDEYAGFTMTLLRMLAFAPAASGGAPVPGAAPAVAAGGRRAAAPVAPAGAGARDAAAHA
MPPVAAAASARPAPAPVAQAAAEPPPAAVAAPRAVPPAAARDVATAKRPAELPVRAEQARPAESDEAAAVAPRESAPDLA
DEPAESPLASQLESSDVALGAGPTPPAEPAAMLEPSLRADTPPMAESAAEAAFAEDVSSLPAALPQASPPSADAAPLAAA
PRPDRVEPAAVRPPAAPVAAPGERSDALRGGGAAAALDVLRNAGMRVSSDRGRAASAAKPAPAAKSAAPRVNVPTPRPRT
AQPSRPAAAADPSAPPPWDDMPPDDYLPISADDHYGPPPDDGYLPVFDSSPDDVRVAPQPAPAPADTRPLPPAIALDAIG
YAGEWPQLAATLTLKGVAYQLAFNSELISAQGGVLKLAVPVPQYADAAQVVKLKTALAEALGKPVEVAVEVGPARRTAAA
LDAVERAKRQREAEQEIGADPFVQQLIRDFGARIVEGSVRPVASDAAAAGPAGQCGAPTLH

Sequences:

>Translated_861_residues
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACR
EIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQ
KIPVTVLSRCLQFNLKQMPAGHIVMHLERILGEERVAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTEAAVSGM
LGALDQTYMVRLLDAIASSDGPEILAIADEMALRSLSFSTALQDLAGLLHRIAWAQFAPASVLDEWPEAADLRRFAEALS
PEQVQLYYQIATVGRGELGLAPDEYAGFTMTLLRMLAFAPAASGGAPVPGAAPAVAAGGRRAAAPVAPAGAGARDAAAHA
MPPVAAAASARPAPAPVAQAAAEPPPAAVAAPRAVPPAAARDVATAKRPAELPVRAEQARPAESDEAAAVAPRESAPDLA
DEPAESPLASQLESSDVALGAGPTPPAEPAAMLEPSLRADTPPMAESAAEAAFAEDVSSLPAALPQASPPSADAAPLAAA
PRPDRVEPAAVRPPAAPVAAPGERSDALRGGGAAAALDVLRNAGMRVSSDRGRAASAAKPAPAAKSAAPRVNVPTPRPRT
AQPSRPAAAADPSAPPPWDDMPPDDYLPISADDHYGPPPDDGYLPVFDSSPDDVRVAPQPAPAPADTRPLPPAIALDAIG
YAGEWPQLAATLTLKGVAYQLAFNSELISAQGGVLKLAVPVPQYADAAQVVKLKTALAEALGKPVEVAVEVGPARRTAAA
LDAVERAKRQREAEQEIGADPFVQQLIRDFGARIVEGSVRPVASDAAAAGPAGQCGAPTLH
>Mature_860_residues
TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAKALNCETGVTSQPCGVCRACRE
IDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARFKVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQK
IPVTVLSRCLQFNLKQMPAGHIVMHLERILGEERVAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTEAAVSGML
GALDQTYMVRLLDAIASSDGPEILAIADEMALRSLSFSTALQDLAGLLHRIAWAQFAPASVLDEWPEAADLRRFAEALSP
EQVQLYYQIATVGRGELGLAPDEYAGFTMTLLRMLAFAPAASGGAPVPGAAPAVAAGGRRAAAPVAPAGAGARDAAAHAM
PPVAAAASARPAPAPVAQAAAEPPPAAVAAPRAVPPAAARDVATAKRPAELPVRAEQARPAESDEAAAVAPRESAPDLAD
EPAESPLASQLESSDVALGAGPTPPAEPAAMLEPSLRADTPPMAESAAEAAFAEDVSSLPAALPQASPPSADAAPLAAAP
RPDRVEPAAVRPPAAPVAAPGERSDALRGGGAAAALDVLRNAGMRVSSDRGRAASAAKPAPAAKSAAPRVNVPTPRPRTA
QPSRPAAAADPSAPPPWDDMPPDDYLPISADDHYGPPPDDGYLPVFDSSPDDVRVAPQPAPAPADTRPLPPAIALDAIGY
AGEWPQLAATLTLKGVAYQLAFNSELISAQGGVLKLAVPVPQYADAAQVVKLKTALAEALGKPVEVAVEVGPARRTAAAL
DAVERAKRQREAEQEIGADPFVQQLIRDFGARIVEGSVRPVASDAAAAGPAGQCGAPTLH

Specific function: The gamma chain seems to interact with the delta subunit to transfer the beta subunit on the DNA [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI6677723, Length=327, Percent_Identity=24.1590214067278, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI194306571, Length=330, Percent_Identity=23.9393939393939, Blast_Score=73, Evalue=1e-12,
Organism=Homo sapiens, GI194306567, Length=330, Percent_Identity=23.9393939393939, Blast_Score=73, Evalue=1e-12,
Organism=Escherichia coli, GI1786676, Length=389, Percent_Identity=55.2699228791774, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1787341, Length=164, Percent_Identity=31.7073170731707, Blast_Score=66, Evalue=1e-11,
Organism=Escherichia coli, GI1787119, Length=230, Percent_Identity=27.3913043478261, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324039, Length=245, Percent_Identity=26.1224489795918, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859927, Length=317, Percent_Identity=22.0820189274448, Blast_Score=73, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022001
- InterPro:   IPR022754
- InterPro:   IPR012763
- InterPro:   IPR021029 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3; PF12168 DNA_pol3_tau_4; PF12170 DNA_pol3_tau_5 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 89319; Mature: 89188

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAK
CCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
GHIVMHLERILGEERVAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTEAAVSGM
HHHHHHHHHHHCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LGALDQTYMVRLLDAIASSDGPEILAIADEMALRSLSFSTALQDLAGLLHRIAWAQFAPA
HHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVLDEWPEAADLRRFAEALSPEQVQLYYQIATVGRGELGLAPDEYAGFTMTLLRMLAFAP
HHHHHCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHCC
AASGGAPVPGAAPAVAAGGRRAAAPVAPAGAGARDAAAHAMPPVAAAASARPAPAPVAQA
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHCCCCCCCCHHHHH
AAEPPPAAVAAPRAVPPAAARDVATAKRPAELPVRAEQARPAESDEAAAVAPRESAPDLA
CCCCCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCEECCCCCCCCCC
DEPAESPLASQLESSDVALGAGPTPPAEPAAMLEPSLRADTPPMAESAAEAAFAEDVSSL
CCCCCCHHHHHHCCCCEEECCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
PAALPQASPPSADAAPLAAAPRPDRVEPAAVRPPAAPVAAPGERSDALRGGGAAAALDVL
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHH
RNAGMRVSSDRGRAASAAKPAPAAKSAAPRVNVPTPRPRTAQPSRPAAAADPSAPPPWDD
HHCCCEEECCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MPPDDYLPISADDHYGPPPDDGYLPVFDSSPDDVRVAPQPAPAPADTRPLPPAIALDAIG
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHCC
YAGEWPQLAATLTLKGVAYQLAFNSELISAQGGVLKLAVPVPQYADAAQVVKLKTALAEA
CCCCCCHHHHHEEECCEEEEEEECCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
LGKPVEVAVEVGPARRTAAALDAVERAKRQREAEQEIGADPFVQQLIRDFGARIVEGSVR
HCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
PVASDAAAAGPAGQCGAPTLH
CCCCHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TYQVLARKWRPKDFASLVGQEHVVRALTHALDGGRLHHAYLFTGTRGVGKTTLSRIFAK
CHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHH
ALNCETGVTSQPCGVCRACREIDEGRFVDYVEMDAASNRGVDEMAALLERAVYAPVDARF
HHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCE
KVYMIDEVHMLTNHAFNAMLKTLEEPPPHVKFILATTDPQKIPVTVLSRCLQFNLKQMPA
EEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCC
GHIVMHLERILGEERVAFEPQALRLLARAAQGSMRDALSLTDQAIAYSANEVTEAAVSGM
HHHHHHHHHHHCCCHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LGALDQTYMVRLLDAIASSDGPEILAIADEMALRSLSFSTALQDLAGLLHRIAWAQFAPA
HHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
SVLDEWPEAADLRRFAEALSPEQVQLYYQIATVGRGELGLAPDEYAGFTMTLLRMLAFAP
HHHHHCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCHHHCCHHHHHHHHHHHCC
AASGGAPVPGAAPAVAAGGRRAAAPVAPAGAGARDAAAHAMPPVAAAASARPAPAPVAQA
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHCCCCCCCCHHHHH
AAEPPPAAVAAPRAVPPAAARDVATAKRPAELPVRAEQARPAESDEAAAVAPRESAPDLA
CCCCCCCHHCCCCCCCCHHHHHHHHHCCCCCCCCCHHHCCCCCCCCCCEECCCCCCCCCC
DEPAESPLASQLESSDVALGAGPTPPAEPAAMLEPSLRADTPPMAESAAEAAFAEDVSSL
CCCCCCHHHHHHCCCCEEECCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHH
PAALPQASPPSADAAPLAAAPRPDRVEPAAVRPPAAPVAAPGERSDALRGGGAAAALDVL
HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHH
RNAGMRVSSDRGRAASAAKPAPAAKSAAPRVNVPTPRPRTAQPSRPAAAADPSAPPPWDD
HHCCCEEECCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MPPDDYLPISADDHYGPPPDDGYLPVFDSSPDDVRVAPQPAPAPADTRPLPPAIALDAIG
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHCC
YAGEWPQLAATLTLKGVAYQLAFNSELISAQGGVLKLAVPVPQYADAAQVVKLKTALAEA
CCCCCCHHHHHEEECCEEEEEEECCHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHH
LGKPVEVAVEVGPARRTAAALDAVERAKRQREAEQEIGADPFVQQLIRDFGARIVEGSVR
HCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCC
PVASDAAAAGPAGQCGAPTLH
CCCCHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534795; 3018672; 9278503; 2186364; 2187190; 2181440; 1575709 [H]