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The map label for this gene is clpB [H]

Identifier: 238027045

GI number: 238027045

Start: 1565478

End: 1568075

Strand: Direct

Name: clpB [H]

Synonym: bglu_1g14230

Alternate gene names: 238027045

Gene position: 1565478-1568075 (Clockwise)

Preceding gene: 238027044

Following gene: 238027056

Centisome position: 40.07

GC content: 66.2

Gene sequence:

>2598_bases
ATGAGAATCGACAAGCTCACCACCAAATTCCAGGAAGCTCTCGCCGACGCGCAGAGCCTCGCTGCCGGCCACGACAATCA
ATACATCGAACCGGTCCACGTGCTGGCCGCGCTGATCGGCCAGCAGGACGGCTCGGCGCGTTCGCTGATGTCGCGCACGG
GCGTCCACGTGCAGGCGCTGCAGGGCGCGCTCAACGAGGCGATCTCGCGCCTGCCGCAGGTGACCGGCACGGGCGGCGAC
ATCCAGGTCGGCCGCGAGTTGGCCGGCCTGCTTAACCAGGCTGACAAGGAAGCGCAGAAGCTCAACGACAGCTTCATCGC
GAGCGAGATGTTCCTGCTCGCGGTGGCCGACGACCGCGGCGACGCGGGCAAGCTCGCGCGCCAGCACGGCCTCACGCGCA
AGTCGCTCGAATCGGCGATCGCGGCCGTGCGCGGCGGCTCGCAAGTGCATAGCGCCGACGCCGAGAGCCAGCGCGAGGCA
CTCAAGAAGTACACCGTCGACCTGACCGAGCGTGCGCGCTCGGGCAAGCTCGACCCCGTGATCGGCCGCGACGACGAGAT
TCGCCGCTCGATCCAGATCCTGCAGCGCCGCACCAAGAACAATCCCGTGCTGATCGGCGAGCCGGGGGTAGGCAAGACCG
CGATCGTCGAGGGACTCGCGCAGCGCATCGTCAACGGGGAGGTGCCCGAGACGCTGAAGAACAAGCGCGTGCTGTCGCTC
GACATGGCGGCGCTCCTGGCCGGCGCGAAGTACCGCGGCGAGTTCGAGGAGCGCCTGAAGGCCGTGCTCAACGACATCGC
CAAGGACGAGGGCCGCACCATCGTGTTCATCGACGAGATCCACACGATGGTCGGTGCGGGCAAGGCCGAGGGCGCGATGG
ATGCCGGCAACATGCTCAAGCCCGCGCTGTCGCGCGGCGAGCTGCACTGCATCGGCGCGACCACGCTCGACGAGTACCGC
AAGTACATCGAAAAGGACGCCGCGCTCGAGCGCCGCTTCCAGAAGGTGATCGTCGACGAGCCGAGCGTCGAGGCGACCAT
CGCGATCCTGCGCGGCCTGCAGGAGAAATACGAACTGCACCATGGCGTGGACATCACCGATCCGGCGATCGTCGCGGCCG
CCGAGCTGTCGCACCGCTATATCACCGACCGCTTCCTGCCCGACAAGGCGATCGACCTGATCGACGAGGCCGCCTCGAAG
ATCAAGATGGAAATCGATTCGAAGCCCGAATCGATGGATCGCCTCGACCGGCGTCTGATCCAGCTGAAGATCGAGCGCGA
GGCCGTGAAGAAGGAGCAGGACGAAGCATCGCAGAAGCGCCTGCAGCTGATCGAGGAAGAGATCGAGCGGCTCGGCCGCG
AGTACGCGGACCTGGAAGAGATCTGGACCGCGGAGAAGGCCGCCGTGCAGGGCAGCGCGCAGCTGAAGGAAGACATCGAC
CGGGTACGCGCGGACATCGCGCGCTTGCAGCGCGAGGGCAAGCTCGAGAAGGTGGCCGAGCTGCAATACGGCAAGCTGCC
GCAACTCGAGGCGCAGCTCAAGCAGGTCACGCAGGCCGAGGAGCAGAACGAGCAGAATCCGTCGCGGCCGCGCCTGTTGC
GCACCCAGGTGGGCGCCGAGGAGATCGCGGAAGTCGTGTCGCGCGCGACCGGCATCCCGGTGTCGCGGATGATGCAGGGC
GAGCGCGAGAAGCTGCTGCACATCGAGGAGAAGCTGCATGAGCGCGTGATCGGCCAGGAAGAGGCGATCGACGCGGTGGC
CGATGCGATCCGCCGCTCGCGCGCCGGGCTGTCCGATCCGAACCGCCCCTACGGCTCGTTCCTGTTTCTCGGCCCGACGG
GTGTGGGCAAGACCGAGGTCTGCAAGGCGCTGGCCGGCTTCCTGTTCGATTCGGAGGATCACCTGATCCGCATCGACATG
AGCGAATTCATGGAGAAGCACAGCGTGGCGCGGCTGATCGGCGCGCCGCCGGGCTATGTCGGCTACGAGGAAGGCGGCTA
TCTGACCGAAGCCGTGCGCCGCAAGCCGTACAGCGTGATCCTGCTCGACGAGATCGAGAAGGCGCACCCGGACGTGTTCA
ACGTGCTGCTGCAAGTGCTCGACGACGGCCGCATGACGGATGGGCAGGGCCGCACGGTAGACTTCAAGAACACCGTGATC
GTGATGACCTCGAACCTCGGTTCGCAGGTGATCCAGTCGATGGCCGGCTCGCCTCAGGAGGCCGTGAAGGATGCCGTATG
GGAAGAGGTGAAGCTGCACTTCCGGCCCGAATTCCTGAACCGGATCGACGACGTCGTGGTGTTCCATGCGCTCGATCGCG
CCAACATCCAGGCGATCGCGAAGATCCAGCTCGCGCGCCTGCATGACCGGCTCGCCAAGCTCGACATGCAGCTCGACGTG
TCCGACGCGGCGCTCGACCAGATCGGCAAGGTCGGCTACGACCCGCTGTTCGGCGCGCGGCCGTTGAAGCGCGCGATCCA
GCAGGAGATCGAGAATCCGGTCGCGAAGCTGATCCTCGCCGGGCGTTTCGGGCCGAAGGACGTGATTCCGGTGGACGTGC
AGGACGGCAAGTTCGTGTTCGACCGCGTGGTCCACTGA

Upstream 100 bases:

>100_bases
GGCCGCCCGCGCGAGCGCGGCACACATCTTGCCTTTCGCTCGCTTGAAAGCCGGATAACCATCCTCATATTGGTGCTATT
CGCAAATTGGAGGTCTCTTC

Downstream 100 bases:

>100_bases
ACCGGGCTCCGGCGCGCGGCTGCCGTGCCCGTGAAAAACCCCGCCTTGGCGGGGTTTTTCCTTTTCCGGGGCCGGCAATG
AGGCAATGGGACCACGTGCT

Product: ATP-dependent Clp protease, ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 865

Protein sequence:

>865_residues
MRIDKLTTKFQEALADAQSLAAGHDNQYIEPVHVLAALIGQQDGSARSLMSRTGVHVQALQGALNEAISRLPQVTGTGGD
IQVGRELAGLLNQADKEAQKLNDSFIASEMFLLAVADDRGDAGKLARQHGLTRKSLESAIAAVRGGSQVHSADAESQREA
LKKYTVDLTERARSGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKNKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGRTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVIVDEPSVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPESMDRLDRRLIQLKIEREAVKKEQDEASQKRLQLIEEEIERLGREYADLEEIWTAEKAAVQGSAQLKEDID
RVRADIARLQREGKLEKVAELQYGKLPQLEAQLKQVTQAEEQNEQNPSRPRLLRTQVGAEEIAEVVSRATGIPVSRMMQG
EREKLLHIEEKLHERVIGQEEAIDAVADAIRRSRAGLSDPNRPYGSFLFLGPTGVGKTEVCKALAGFLFDSEDHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQSMAGSPQEAVKDAVWEEVKLHFRPEFLNRIDDVVVFHALDRANIQAIAKIQLARLHDRLAKLDMQLDV
SDAALDQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDVQDGKFVFDRVVH

Sequences:

>Translated_865_residues
MRIDKLTTKFQEALADAQSLAAGHDNQYIEPVHVLAALIGQQDGSARSLMSRTGVHVQALQGALNEAISRLPQVTGTGGD
IQVGRELAGLLNQADKEAQKLNDSFIASEMFLLAVADDRGDAGKLARQHGLTRKSLESAIAAVRGGSQVHSADAESQREA
LKKYTVDLTERARSGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKNKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGRTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVIVDEPSVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPESMDRLDRRLIQLKIEREAVKKEQDEASQKRLQLIEEEIERLGREYADLEEIWTAEKAAVQGSAQLKEDID
RVRADIARLQREGKLEKVAELQYGKLPQLEAQLKQVTQAEEQNEQNPSRPRLLRTQVGAEEIAEVVSRATGIPVSRMMQG
EREKLLHIEEKLHERVIGQEEAIDAVADAIRRSRAGLSDPNRPYGSFLFLGPTGVGKTEVCKALAGFLFDSEDHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQSMAGSPQEAVKDAVWEEVKLHFRPEFLNRIDDVVVFHALDRANIQAIAKIQLARLHDRLAKLDMQLDV
SDAALDQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDVQDGKFVFDRVVH
>Mature_865_residues
MRIDKLTTKFQEALADAQSLAAGHDNQYIEPVHVLAALIGQQDGSARSLMSRTGVHVQALQGALNEAISRLPQVTGTGGD
IQVGRELAGLLNQADKEAQKLNDSFIASEMFLLAVADDRGDAGKLARQHGLTRKSLESAIAAVRGGSQVHSADAESQREA
LKKYTVDLTERARSGKLDPVIGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKNKRVLSL
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGRTIVFIDEIHTMVGAGKAEGAMDAGNMLKPALSRGELHCIGATTLDEYR
KYIEKDAALERRFQKVIVDEPSVEATIAILRGLQEKYELHHGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASK
IKMEIDSKPESMDRLDRRLIQLKIEREAVKKEQDEASQKRLQLIEEEIERLGREYADLEEIWTAEKAAVQGSAQLKEDID
RVRADIARLQREGKLEKVAELQYGKLPQLEAQLKQVTQAEEQNEQNPSRPRLLRTQVGAEEIAEVVSRATGIPVSRMMQG
EREKLLHIEEKLHERVIGQEEAIDAVADAIRRSRAGLSDPNRPYGSFLFLGPTGVGKTEVCKALAGFLFDSEDHLIRIDM
SEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
VMTSNLGSQVIQSMAGSPQEAVKDAVWEEVKLHFRPEFLNRIDDVVVFHALDRANIQAIAKIQLARLHDRLAKLDMQLDV
SDAALDQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILAGRFGPKDVIPVDVQDGKFVFDRVVH

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=303, Percent_Identity=36.963696369637, Blast_Score=196, Evalue=6e-50,
Organism=Escherichia coli, GI1788943, Length=860, Percent_Identity=66.046511627907, Blast_Score=1162, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=437, Percent_Identity=39.1304347826087, Blast_Score=285, Evalue=8e-78,
Organism=Saccharomyces cerevisiae, GI6320464, Length=712, Percent_Identity=52.1067415730337, Blast_Score=757, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=865, Percent_Identity=43.121387283237, Blast_Score=696, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95884; Mature: 95884

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIDKLTTKFQEALADAQSLAAGHDNQYIEPVHVLAALIGQQDGSARSLMSRTGVHVQAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHH
QGALNEAISRLPQVTGTGGDIQVGRELAGLLNQADKEAQKLNDSFIASEMFLLAVADDRG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
DAGKLARQHGLTRKSLESAIAAVRGGSQVHSADAESQREALKKYTVDLTERARSGKLDPV
CHHHHHHHHCCCHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
IGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKNKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCHHH
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGRTIVFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALSRGELHCIGATTLDEYRKYIEKDAALERRFQKVIVDEPSVEATIAILRGLQEKYELH
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASKIKMEIDSKPESMDRLDRRLI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHH
QLKIEREAVKKEQDEASQKRLQLIEEEIERLGREYADLEEIWTAEKAAVQGSAQLKEDID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RVRADIARLQREGKLEKVAELQYGKLPQLEAQLKQVTQAEEQNEQNPSRPRLLRTQVGAE
HHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHH
EIAEVVSRATGIPVSRMMQGEREKLLHIEEKLHERVIGQEEAIDAVADAIRRSRAGLSDP
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
NRPYGSFLFLGPTGVGKTEVCKALAGFLFDSEDHLIRIDMSEFMEKHSVARLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
VMTSNLGSQVIQSMAGSPQEAVKDAVWEEVKLHFRPEFLNRIDDVVVFHALDRANIQAIA
EEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
KIQLARLHDRLAKLDMQLDVSDAALDQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GRFGPKDVIPVDVQDGKFVFDRVVH
CCCCCCCCEEEECCCCCHHHHHHCC
>Mature Secondary Structure
MRIDKLTTKFQEALADAQSLAAGHDNQYIEPVHVLAALIGQQDGSARSLMSRTGVHVQAL
CCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHCCCHHHHH
QGALNEAISRLPQVTGTGGDIQVGRELAGLLNQADKEAQKLNDSFIASEMFLLAVADDRG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCC
DAGKLARQHGLTRKSLESAIAAVRGGSQVHSADAESQREALKKYTVDLTERARSGKLDPV
CHHHHHHHHCCCHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
IGRDDEIRRSIQILQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPETLKNKRVLSL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHCCCCHHH
DMAALLAGAKYRGEFEERLKAVLNDIAKDEGRTIVFIDEIHTMVGAGKAEGAMDAGNMLK
HHHHHHHCCHHCCCHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCCCCCCCCCCHHHH
PALSRGELHCIGATTLDEYRKYIEKDAALERRFQKVIVDEPSVEATIAILRGLQEKYELH
HHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
HGVDITDPAIVAAAELSHRYITDRFLPDKAIDLIDEAASKIKMEIDSKPESMDRLDRRLI
CCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEHHCCCCCHHHHHHHHHHH
QLKIEREAVKKEQDEASQKRLQLIEEEIERLGREYADLEEIWTAEKAAVQGSAQLKEDID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
RVRADIARLQREGKLEKVAELQYGKLPQLEAQLKQVTQAEEQNEQNPSRPRLLRTQVGAE
HHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCHH
EIAEVVSRATGIPVSRMMQGEREKLLHIEEKLHERVIGQEEAIDAVADAIRRSRAGLSDP
HHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
NRPYGSFLFLGPTGVGKTEVCKALAGFLFDSEDHLIRIDMSEFMEKHSVARLIGAPPGYV
CCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCC
GYEEGGYLTEAVRRKPYSVILLDEIEKAHPDVFNVLLQVLDDGRMTDGQGRTVDFKNTVI
CCCCCCHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCCCCCCCCEEEECCEEE
VMTSNLGSQVIQSMAGSPQEAVKDAVWEEVKLHFRPEFLNRIDDVVVFHALDRANIQAIA
EEECCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
KIQLARLHDRLAKLDMQLDVSDAALDQIGKVGYDPLFGARPLKRAIQQEIENPVAKLILA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
GRFGPKDVIPVDVQDGKFVFDRVVH
CCCCCCCCEEEECCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]