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The map label for this gene is rnhA [H]

Identifier: 238026772

GI number: 238026772

Start: 1238950

End: 1239399

Strand: Reverse

Name: rnhA [H]

Synonym: bglu_1g11300

Alternate gene names: 238026772

Gene position: 1239399-1238950 (Counterclockwise)

Preceding gene: 238026773

Following gene: 238026771

Centisome position: 31.73

GC content: 65.78

Gene sequence:

>450_bases
ATGACGTTGCAACTGATCGACATCTACACCGACGGCGCCTGCAAGGGCAATCCCGGCCCCGGCGGCTGGGGCGCGCTGCT
GCGCTTCGGCGACCAGGAAAAGGAACTGTTCGGCGGCGAGGCCGGCACCACCAACAACCGGATGGAACTGCTCGCCGTGA
TCAGGGCGCTGGAAGCGCTCAAGCGCCCGTGCCGCGTGATCGTCCATACCGATTCGCAGTACGTGCAGAAAGGCATCAGC
GAATGGATCCACGGCTGGAAGAAAAAGGGCTGGGTGACGGCCGCGAAGACGCCGGTGAAGAACGCCGATCTCTGGAAACA
GCTCGACGCGCTGGTCGGCCAGCACGAAATCGAGTGGCGCTGGGTCAAGGGCCACGCCGGGCACGCCGAGAACGAGCGCG
CCGATGCGCTCGCCAACCGCGGCGTCGAATCGCTGTCGCAGCGGGCATGA

Upstream 100 bases:

>100_bases
TGCGCGAGATGCGGCTCGTCGGCCCGATCCGGGTCAGGAAACCCGTTCGCGCACCGGGCCTCGCGCCCGCCGCGACCCCT
ACCACTCATCAAGAACACTC

Downstream 100 bases:

>100_bases
GCAGCCATCCCGCCGCCGGCCGCGCCGCGAGCCCGCATTCCGCCGCGCCGGGGCCGCTGCCCGGCGCCGCCCTGTCCGGC
CCGCGCGCCGGCACCTTTTG

Product: RNase H

Products: NA

Alternate protein names: RNase H [H]

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MTLQLIDIYTDGACKGNPGPGGWGALLRFGDQEKELFGGEAGTTNNRMELLAVIRALEALKRPCRVIVHTDSQYVQKGIS
EWIHGWKKKGWVTAAKTPVKNADLWKQLDALVGQHEIEWRWVKGHAGHAENERADALANRGVESLSQRA

Sequences:

>Translated_149_residues
MTLQLIDIYTDGACKGNPGPGGWGALLRFGDQEKELFGGEAGTTNNRMELLAVIRALEALKRPCRVIVHTDSQYVQKGIS
EWIHGWKKKGWVTAAKTPVKNADLWKQLDALVGQHEIEWRWVKGHAGHAENERADALANRGVESLSQRA
>Mature_148_residues
TLQLIDIYTDGACKGNPGPGGWGALLRFGDQEKELFGGEAGTTNNRMELLAVIRALEALKRPCRVIVHTDSQYVQKGISE
WIHGWKKKGWVTAAKTPVKNADLWKQLDALVGQHEIEWRWVKGHAGHAENERADALANRGVESLSQRA

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids [H]

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain [H]

Homologues:

Organism=Homo sapiens, GI21359816, Length=150, Percent_Identity=35.3333333333333, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1786408, Length=136, Percent_Identity=64.7058823529412, Blast_Score=193, Evalue=4e-51,
Organism=Caenorhabditis elegans, GI115532542, Length=148, Percent_Identity=39.8648648648649, Blast_Score=99, Evalue=6e-22,
Organism=Drosophila melanogaster, GI45552509, Length=153, Percent_Identity=33.9869281045752, Blast_Score=80, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17137476, Length=151, Percent_Identity=34.4370860927152, Blast_Score=80, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156 [H]

Pfam domain/function: PF00075 RnaseH [H]

EC number: =3.1.26.4 [H]

Molecular weight: Translated: 16540; Mature: 16409

Theoretical pI: Translated: 8.74; Mature: 8.74

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLQLIDIYTDGACKGNPGPGGWGALLRFGDQEKELFGGEAGTTNNRMELLAVIRALEAL
CEEEEEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KRPCRVIVHTDSQYVQKGISEWIHGWKKKGWVTAAKTPVKNADLWKQLDALVGQHEIEWR
HCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCCEEE
WVKGHAGHAENERADALANRGVESLSQRA
EECCCCCCCCCHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure 
TLQLIDIYTDGACKGNPGPGGWGALLRFGDQEKELFGGEAGTTNNRMELLAVIRALEAL
EEEEEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
KRPCRVIVHTDSQYVQKGISEWIHGWKKKGWVTAAKTPVKNADLWKQLDALVGQHEIEWR
HCCCEEEEECCHHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHCCCCCEEE
WVKGHAGHAENERADALANRGVESLSQRA
EECCCCCCCCCHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14500782 [H]