Click here to switch to the map view.

The map label for this gene is pdhA [H]

Identifier: 238026712

GI number: 238026712

Start: 1169541

End: 1170653

Strand: Reverse

Name: pdhA [H]

Synonym: bglu_1g10690

Alternate gene names: 238026712

Gene position: 1170653-1169541 (Counterclockwise)

Preceding gene: 238026713

Following gene: 238026710

Centisome position: 29.97

GC content: 71.07

Gene sequence:

>1113_bases
ATGGACACGATGCTTCTCAAACGCACCCGACACACGGAGCATGCCGCGCAAGCCTGCATCCGCTGCATCGAGGACACCCG
CGGCGACGCAGGCGAACACGATTCGCCCCTGCTCACCGTGTCGGCGCTGATCCGCGACCTGCATCAGGACGCCACGGTCG
ACGGCCAGTTCTGGTTCGTCGACGATCGTGCCGAGCAGCAGCAGCGCAACGCGGCGATCGGTGCCTGGCCGCTGTGGATC
AGCGAGCGAGCGCGCAACGACGAGCGCCCGCTGTTCTACCTCACGCAGTCCCCCACCTCGCGCCATCTCTCGATGCTCAC
CGCCCAGACCGCGGAGCGCGGCATCATCCTCAACGACATCGAATCGTCGCCGTCGCGCTGGGCCAAGGGCGCGCACCCGT
GGCTGCCGCTCTGGCTCGCCTCGAACCGCCAGTGCATGCCGTTCGATCCGGCCTGCGGCGAGGAGGTCAAGGCGATCGTG
GCCGGCGCGCTGCACGATCTCTACATGAAGGGCGAGCCCGGCTTCTGCTATCTGACACTGCACGGCGAGCCCATCGAGGC
GCTGCGCTGCGACCGGACCCAGGCCTATCTCGGCATGTATCGCCTGTCGGAGCCGAAGGCGTCCCAGCCGCAGATCCGGC
TGCTCGGCGCCGGGCTGGTGCTGCGCGAGGTGCGTGCCGCGGCGCAGTTGCTCAAGGACGACTGGGGCGTCGACAGCGAG
GTGTGGAGCTGTCCGAGCTACACCCGGCTCGCGCGCGACTCGGCCGACGCGCAGCGCTGGAACGCCAGCCTCGGCAGCTG
TGCGCGCCGAACCTCGCACCTGCATGCCTGCCTGAACCGCAGCCGGCAGCCGGTCCTCGCCGTGACGGCCTACGCCGAGT
TCGTCGCCGCCCAGCTGGGCCCCTATCTCGACGCGCCGTTCAGCGCGATCGGCGCCGACACGTTCGCGCCGAACCAGTGT
CCGGACCGGCGCTGGATCGCCTACCGCGCCCTCGATGCGCTCGCCCGGCAAGGGCAGCTCGCCGGCGCCGACCTGGCGCG
GGCCCTCGACCGCTACGGGCTCGGCGAACTCGTCCCGCGCCAAGCGCGGCCCGACGGCGGCGCCTGCGCGTGA

Upstream 100 bases:

>100_bases
GCCGCCGTGAAGGCCGGATAAGGGCGGCACCCGCGCGGCGCGAGCCGCTCGCGTCGCCGCCGCGCCCGACCCACGCAGCA
CCGCCATCCGAGGCTTCAGC

Downstream 100 bases:

>100_bases
ATGCACGGCGCCCCGCCCGGCCGCGTCAGCCCTCGCTCAACGCGGCCAGCCCGAGCCTCGACGCGACGATCACGGCCTGC
TTGGCGGTGGACACGTCGAG

Product: pyruvate dehydrogenase (lipoamide)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MDTMLLKRTRHTEHAAQACIRCIEDTRGDAGEHDSPLLTVSALIRDLHQDATVDGQFWFVDDRAEQQQRNAAIGAWPLWI
SERARNDERPLFYLTQSPTSRHLSMLTAQTAERGIILNDIESSPSRWAKGAHPWLPLWLASNRQCMPFDPACGEEVKAIV
AGALHDLYMKGEPGFCYLTLHGEPIEALRCDRTQAYLGMYRLSEPKASQPQIRLLGAGLVLREVRAAAQLLKDDWGVDSE
VWSCPSYTRLARDSADAQRWNASLGSCARRTSHLHACLNRSRQPVLAVTAYAEFVAAQLGPYLDAPFSAIGADTFAPNQC
PDRRWIAYRALDALARQGQLAGADLARALDRYGLGELVPRQARPDGGACA

Sequences:

>Translated_370_residues
MDTMLLKRTRHTEHAAQACIRCIEDTRGDAGEHDSPLLTVSALIRDLHQDATVDGQFWFVDDRAEQQQRNAAIGAWPLWI
SERARNDERPLFYLTQSPTSRHLSMLTAQTAERGIILNDIESSPSRWAKGAHPWLPLWLASNRQCMPFDPACGEEVKAIV
AGALHDLYMKGEPGFCYLTLHGEPIEALRCDRTQAYLGMYRLSEPKASQPQIRLLGAGLVLREVRAAAQLLKDDWGVDSE
VWSCPSYTRLARDSADAQRWNASLGSCARRTSHLHACLNRSRQPVLAVTAYAEFVAAQLGPYLDAPFSAIGADTFAPNQC
PDRRWIAYRALDALARQGQLAGADLARALDRYGLGELVPRQARPDGGACA
>Mature_370_residues
MDTMLLKRTRHTEHAAQACIRCIEDTRGDAGEHDSPLLTVSALIRDLHQDATVDGQFWFVDDRAEQQQRNAAIGAWPLWI
SERARNDERPLFYLTQSPTSRHLSMLTAQTAERGIILNDIESSPSRWAKGAHPWLPLWLASNRQCMPFDPACGEEVKAIV
AGALHDLYMKGEPGFCYLTLHGEPIEALRCDRTQAYLGMYRLSEPKASQPQIRLLGAGLVLREVRAAAQLLKDDWGVDSE
VWSCPSYTRLARDSADAQRWNASLGSCARRTSHLHACLNRSRQPVLAVTAYAEFVAAQLGPYLDAPFSAIGADTFAPNQC
PDRRWIAYRALDALARQGQLAGADLARALDRYGLGELVPRQARPDGGACA

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=229, Percent_Identity=30.1310043668122, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 41031; Mature: 41031

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTMLLKRTRHTEHAAQACIRCIEDTRGDAGEHDSPLLTVSALIRDLHQDATVDGQFWFV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEE
DDRAEQQQRNAAIGAWPLWISERARNDERPLFYLTQSPTSRHLSMLTAQTAERGIILNDI
CCHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEECC
ESSPSRWAKGAHPWLPLWLASNRQCMPFDPACGEEVKAIVAGALHDLYMKGEPGFCYLTL
CCCHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
HGEPIEALRCDRTQAYLGMYRLSEPKASQPQIRLLGAGLVLREVRAAAQLLKDDWGVDSE
CCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHH
VWSCPSYTRLARDSADAQRWNASLGSCARRTSHLHACLNRSRQPVLAVTAYAEFVAAQLG
HHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHC
PYLDAPFSAIGADTFAPNQCPDRRWIAYRALDALARQGQLAGADLARALDRYGLGELVPR
CCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHCCC
QARPDGGACA
CCCCCCCCCC
>Mature Secondary Structure
MDTMLLKRTRHTEHAAQACIRCIEDTRGDAGEHDSPLLTVSALIRDLHQDATVDGQFWFV
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEE
DDRAEQQQRNAAIGAWPLWISERARNDERPLFYLTQSPTSRHLSMLTAQTAERGIILNDI
CCHHHHHHHCCCCCCCHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCEEEECC
ESSPSRWAKGAHPWLPLWLASNRQCMPFDPACGEEVKAIVAGALHDLYMKGEPGFCYLTL
CCCHHHHHCCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEE
HGEPIEALRCDRTQAYLGMYRLSEPKASQPQIRLLGAGLVLREVRAAAQLLKDDWGVDSE
CCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHH
VWSCPSYTRLARDSADAQRWNASLGSCARRTSHLHACLNRSRQPVLAVTAYAEFVAAQLG
HHCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHC
PYLDAPFSAIGADTFAPNQCPDRRWIAYRALDALARQGQLAGADLARALDRYGLGELVPR
CCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCHHHCCC
QARPDGGACA
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]