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The map label for this gene is hldE [H]

Identifier: 238026541

GI number: 238026541

Start: 963263

End: 964243

Strand: Direct

Name: hldE [H]

Synonym: bglu_1g08850

Alternate gene names: 238026541

Gene position: 963263-964243 (Clockwise)

Preceding gene: 238026540

Following gene: 238026542

Centisome position: 24.66

GC content: 72.17

Gene sequence:

>981_bases
ATGTCGCCGCTCACTCCTCCACGCGCGGCTGAGGCCGCGCCCGCCGTGCCCGCGTCCGTCGCGCGCGAGCGCCTCGCCGC
CTCGCGCGTGCTGGTGGTCGGCGACGTGATGCTGGACCGCTACTGGTTCGGCAACGTGAACCGCATCTCGCCGGAGGCGC
CGGTGCCGGTCGTCCACGTGCAGCGCCAGGAGGAGCGGCTCGGCGGCGCCGCGAACGTCGCGCGCAACATCGTGACGCTC
GGCGCGGCCGCGGGGCTGCTCTGCGTGGTCGGCACCGACGAGCCGGGCGAGCGTATCGTCGGGCTGCTCGGCGAGAGCGG
CGTCGAGACCCATCTCGAACGCGACGCGCTGTTGCCCACCACCATCAAGCTGCGCGTGCTCGCGCAGCAGCAGCAACTGC
TGCGCGTGGACTTCGAGGCGGCGCCGCAGCACGAGGTGCTGCTGGCCGGCCTGGCGCGCTTCGAGACGCTGCTGCCCTCG
TATGGCGTCGTGCTGATGTCCGACTATGCCAAGGGCGGCCTTACCCACGTGACCACCATGATCGCGACTGCGCGCGCGGC
CGGGTTGCCGGTGCTGGTCGATCCGAAGGGCGCCGACTGGGCGCGCTACCGCGGCGCCTCGCTGATCACGCCGAACCGCG
CCGAACTGCGCGAGGTGATCGGCCAGTGGCGCTCCGAGGACGAATTGCGCGCGCGCGTGGCCGAGCTGCGCGCCGAGCTG
GCGCTCGACGCGCTGCTGTTGACGCGTTCGGAGGAGGGCATGACGCTGTTTTCCGACGCGGGCGAACTCGATGTCGCGGC
GCTCGCGCGCGAGGTGTTCGACGTGTCGGGCGCGGGCGATACCGTGATCGCGACCGTGGCCGCGATGCTCGGCGCCGGGG
TGTCGCTCGACGAGGCGGTGATGCTCGCGAACCGCGCGGCCGGCATCGTGGTCGGCAAGCTCGGCACGGCCACCGTCGAA
TACGACGAACTGTTCCATTGA

Upstream 100 bases:

>100_bases
TCGGTGCTGAACGCGCCGGTGATCTTCGACGGCCGCAATCTCTACGAACCCGACGCGATGGCCGAACTCGGGATCGACTA
CTACGCCATCGGACGCCCGC

Downstream 100 bases:

>100_bases
GCGGCGCCCGGGCGCGCCGCGCGACCCATTCATCCTTCTGACAGCAGGACGATCATGACTCTCATCGTCACCGGCGCGGC
CGGCTTCATCGGCGCGAATC

Product: D-glycero-D-manno-heptose 1-phosphate synthase

Products: NA

Alternate protein names: D-beta-D-heptose 7-phosphate kinase; D-beta-D-heptose 7-phosphotransferase; D-beta-D-heptose 1-phosphate adenosyltransferase [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSPLTPPRAAEAAPAVPASVARERLAASRVLVVGDVMLDRYWFGNVNRISPEAPVPVVHVQRQEERLGGAANVARNIVTL
GAAAGLLCVVGTDEPGERIVGLLGESGVETHLERDALLPTTIKLRVLAQQQQLLRVDFEAAPQHEVLLAGLARFETLLPS
YGVVLMSDYAKGGLTHVTTMIATARAAGLPVLVDPKGADWARYRGASLITPNRAELREVIGQWRSEDELRARVAELRAEL
ALDALLLTRSEEGMTLFSDAGELDVAALAREVFDVSGAGDTVIATVAAMLGAGVSLDEAVMLANRAAGIVVGKLGTATVE
YDELFH

Sequences:

>Translated_326_residues
MSPLTPPRAAEAAPAVPASVARERLAASRVLVVGDVMLDRYWFGNVNRISPEAPVPVVHVQRQEERLGGAANVARNIVTL
GAAAGLLCVVGTDEPGERIVGLLGESGVETHLERDALLPTTIKLRVLAQQQQLLRVDFEAAPQHEVLLAGLARFETLLPS
YGVVLMSDYAKGGLTHVTTMIATARAAGLPVLVDPKGADWARYRGASLITPNRAELREVIGQWRSEDELRARVAELRAEL
ALDALLLTRSEEGMTLFSDAGELDVAALAREVFDVSGAGDTVIATVAAMLGAGVSLDEAVMLANRAAGIVVGKLGTATVE
YDELFH
>Mature_325_residues
SPLTPPRAAEAAPAVPASVARERLAASRVLVVGDVMLDRYWFGNVNRISPEAPVPVVHVQRQEERLGGAANVARNIVTLG
AAAGLLCVVGTDEPGERIVGLLGESGVETHLERDALLPTTIKLRVLAQQQQLLRVDFEAAPQHEVLLAGLARFETLLPSY
GVVLMSDYAKGGLTHVTTMIATARAAGLPVLVDPKGADWARYRGASLITPNRAELREVIGQWRSEDELRARVAELRAELA
LDALLLTRSEEGMTLFSDAGELDVAALAREVFDVSGAGDTVIATVAAMLGAGVSLDEAVMLANRAAGIVVGKLGTATVEY
DELFH

Specific function: Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose [H]

COG id: COG2870

COG function: function code M; ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789432, Length=303, Percent_Identity=51.1551155115512, Blast_Score=276, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023030
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR011913
- InterPro:   IPR011914
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2; PF00294 PfkB [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 34577; Mature: 34446

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPLTPPRAAEAAPAVPASVARERLAASRVLVVGDVMLDRYWFGNVNRISPEAPVPVVHV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCCCCCCCCEEEE
QRQEERLGGAANVARNIVTLGAAAGLLCVVGTDEPGERIVGLLGESGVETHLERDALLPT
CCHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHCCCCCCC
TIKLRVLAQQQQLLRVDFEAAPQHEVLLAGLARFETLLPSYGVVLMSDYAKGGLTHVTTM
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
IATARAAGLPVLVDPKGADWARYRGASLITPNRAELREVIGQWRSEDELRARVAELRAEL
HHHHHHCCCCEEECCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ALDALLLTRSEEGMTLFSDAGELDVAALAREVFDVSGAGDTVIATVAAMLGAGVSLDEAV
HHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHH
MLANRAAGIVVGKLGTATVEYDELFH
HHHHCCCCEEEECCCCCEECHHHHCC
>Mature Secondary Structure 
SPLTPPRAAEAAPAVPASVARERLAASRVLVVGDVMLDRYWFGNVNRISPEAPVPVVHV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEHHHHHHHHHCCCCCCCCCCCCCCEEEE
QRQEERLGGAANVARNIVTLGAAAGLLCVVGTDEPGERIVGLLGESGVETHLERDALLPT
CCHHHHCCHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHCCCCHHHHHHCCCCCCC
TIKLRVLAQQQQLLRVDFEAAPQHEVLLAGLARFETLLPSYGVVLMSDYAKGGLTHVTTM
HHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
IATARAAGLPVLVDPKGADWARYRGASLITPNRAELREVIGQWRSEDELRARVAELRAEL
HHHHHHCCCCEEECCCCCCHHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ALDALLLTRSEEGMTLFSDAGELDVAALAREVFDVSGAGDTVIATVAAMLGAGVSLDEAV
HHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHH
MLANRAAGIVVGKLGTATVEYDELFH
HHHHCCCCEEEECCCCCEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA