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The map label for this gene is serC [H]

Identifier: 238026531

GI number: 238026531

Start: 952542

End: 953624

Strand: Direct

Name: serC [H]

Synonym: bglu_1g08750

Alternate gene names: 238026531

Gene position: 952542-953624 (Clockwise)

Preceding gene: 238026530

Following gene: 238026532

Centisome position: 24.38

GC content: 66.02

Gene sequence:

>1083_bases
ATGCGCGTGTTTAATTTCTCCGCGGGGCCCGCGGCGTTGCCCGAGGACGTGCTGCGCCAGGCGGCCGACGAGATGCTCGA
CTGGAACGGCAGCGGCATGAGCGTGATGGAGATGAGCCACCGCGGGCGCGAGTTCACCTCGATCCACGAGACCGCATTGG
CCGACCTGCGCGAACTGATGGCGGTGCCCGACAATTACCGCGTGCTGTTCCTGCAGGGCGGCGGGATCGCCGAGAATGCG
ATCGTCCCCATGAACCTGCTCGGCACGCACCAGACCGCCGATTTCGTCGTGACGGGCTCGTGGTCGCAGAAGTCGTTCAA
GGAGGCGCAGAAGTACTGCACGCCGCATCTGGCCGCGAGCGGGCGCACCGAGGACGGCTACACGCGCGTGCCGGCGTTCT
CGGAATGGCAGCTGTCGGCCGATCCCGCCTACGTGCATCTCTGCACCAACGAGACGATCGACGGCGTCGAGGCGTTCGAG
GTGCCCGATACCGGAGACCTGCCGCTCGTGGCCGACGTCTCCTCGCACATCCTGTCACGGCCGATCGACGTCACCCGGTA
CGGCGCGCTGTTCGGCGGCGCGCAGAAGAACATCGGAATGGCGGGCGTGACGCTGGTGGTGGTGCGCGAGGATCTGCTCG
ATCGCGCGCTGCCGATCTGCCCGTCGGCGTTCGAATGGAAAACGGTCGCCGCGAACAATTCGATGTACAACACGCCGCCC
ACCTACGCGATCTACATCGCCGGCCTCGTGTTCAAGTGGCTGAAGGCGCAGGGCGGCCTCGCCGCGATCGCCGCGCGCAA
CGCCGAAAAGGCGGCGCTGCTCTATGACGCGATCGATGCGAGCAGCTTCTATCTCAACAAGGTCGAGAAGGCGTCGCGTT
CGCGTATGAACGTGCCGTTCTTCCTGGCCGACGAAACGCGCAACGAAGACTTCCTTGCCGGCGCGAAGGCGCGCGGGCTG
CTGCAGCTGAAGGGCCACAAGTCCGTCGGCGGTATGCGGGCGTCGATCTACAACGCGGTGCCGCTCGCGGGCGTGAAGGC
GCTCGTCGAGTACATGAAAGAATTCGAGCGCGCGCAGGCCTGA

Upstream 100 bases:

>100_bases
TGCGATAATGGCCGTTTGCGCACCAACGCAGGCGGCCATTTCTTTTTGGTGCGGCACCCGGTTCGTTCCGGCGCTGCCGC
GTCTCTCCCGAGGTTCTACG

Downstream 100 bases:

>100_bases
CGGCGGCGCGCCCATCAAAGCACGGCAAACCAGCATGGACGACGAACTCAATTCCCGGCTCAAACCGCTGCGCGAGCGTA
TCGACGCGATCGATGCGCAG

Product: 3-phosphoserine/phosphohydroxythreonine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRVFNFSAGPAALPEDVLRQAADEMLDWNGSGMSVMEMSHRGREFTSIHETALADLRELMAVPDNYRVLFLQGGGIAENA
IVPMNLLGTHQTADFVVTGSWSQKSFKEAQKYCTPHLAASGRTEDGYTRVPAFSEWQLSADPAYVHLCTNETIDGVEAFE
VPDTGDLPLVADVSSHILSRPIDVTRYGALFGGAQKNIGMAGVTLVVVREDLLDRALPICPSAFEWKTVAANNSMYNTPP
TYAIYIAGLVFKWLKAQGGLAAIAARNAEKAALLYDAIDASSFYLNKVEKASRSRMNVPFFLADETRNEDFLAGAKARGL
LQLKGHKSVGGMRASIYNAVPLAGVKALVEYMKEFERAQA

Sequences:

>Translated_360_residues
MRVFNFSAGPAALPEDVLRQAADEMLDWNGSGMSVMEMSHRGREFTSIHETALADLRELMAVPDNYRVLFLQGGGIAENA
IVPMNLLGTHQTADFVVTGSWSQKSFKEAQKYCTPHLAASGRTEDGYTRVPAFSEWQLSADPAYVHLCTNETIDGVEAFE
VPDTGDLPLVADVSSHILSRPIDVTRYGALFGGAQKNIGMAGVTLVVVREDLLDRALPICPSAFEWKTVAANNSMYNTPP
TYAIYIAGLVFKWLKAQGGLAAIAARNAEKAALLYDAIDASSFYLNKVEKASRSRMNVPFFLADETRNEDFLAGAKARGL
LQLKGHKSVGGMRASIYNAVPLAGVKALVEYMKEFERAQA
>Mature_360_residues
MRVFNFSAGPAALPEDVLRQAADEMLDWNGSGMSVMEMSHRGREFTSIHETALADLRELMAVPDNYRVLFLQGGGIAENA
IVPMNLLGTHQTADFVVTGSWSQKSFKEAQKYCTPHLAASGRTEDGYTRVPAFSEWQLSADPAYVHLCTNETIDGVEAFE
VPDTGDLPLVADVSSHILSRPIDVTRYGALFGGAQKNIGMAGVTLVVVREDLLDRALPICPSAFEWKTVAANNSMYNTPP
TYAIYIAGLVFKWLKAQGGLAAIAARNAEKAALLYDAIDASSFYLNKVEKASRSRMNVPFFLADETRNEDFLAGAKARGL
LQLKGHKSVGGMRASIYNAVPLAGVKALVEYMKEFERAQA

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=47.0914127423823, Blast_Score=342, Evalue=2e-94,
Organism=Homo sapiens, GI10863955, Length=357, Percent_Identity=42.8571428571429, Blast_Score=294, Evalue=7e-80,
Organism=Escherichia coli, GI1787136, Length=357, Percent_Identity=57.1428571428571, Blast_Score=417, Evalue=1e-118,
Organism=Caenorhabditis elegans, GI17506897, Length=362, Percent_Identity=45.8563535911602, Blast_Score=339, Evalue=1e-93,
Organism=Saccharomyces cerevisiae, GI6324758, Length=386, Percent_Identity=41.4507772020725, Blast_Score=289, Evalue=6e-79,
Organism=Drosophila melanogaster, GI21356589, Length=366, Percent_Identity=48.6338797814208, Blast_Score=361, Evalue=1e-100,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39223; Mature: 39223

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVFNFSAGPAALPEDVLRQAADEMLDWNGSGMSVMEMSHRGREFTSIHETALADLRELM
CEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHH
AVPDNYRVLFLQGGGIAENAIVPMNLLGTHQTADFVVTGSWSQKSFKEAQKYCTPHLAAS
HCCCCCEEEEEECCCCCCCCEEEEHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHCC
GRTEDGYTRVPAFSEWQLSADPAYVHLCTNETIDGVEAFEVPDTGDLPLVADVSSHILSR
CCCCCCCEECCCCCCCEECCCCEEEEEECCCCCCCCEEECCCCCCCCCEEHHHHHHHHHC
PIDVTRYGALFGGAQKNIGMAGVTLVVVREDLLDRALPICPSAFEWKTVAANNSMYNTPP
CCCHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCC
TYAIYIAGLVFKWLKAQGGLAAIAARNAEKAALLYDAIDASSFYLNKVEKASRSRMNVPF
CHHHHHHHHHHHHHHCCCCEEEEEECCCCHHEEEEHHHCCCHHHHHHHHHHHHHCCCCCE
FLADETRNEDFLAGAKARGLLQLKGHKSVGGMRASIYNAVPLAGVKALVEYMKEFERAQA
EEECCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRVFNFSAGPAALPEDVLRQAADEMLDWNGSGMSVMEMSHRGREFTSIHETALADLRELM
CEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEHHHHCCCHHHHHHHHHHHHHHHHH
AVPDNYRVLFLQGGGIAENAIVPMNLLGTHQTADFVVTGSWSQKSFKEAQKYCTPHLAAS
HCCCCCEEEEEECCCCCCCCEEEEHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCHHCC
GRTEDGYTRVPAFSEWQLSADPAYVHLCTNETIDGVEAFEVPDTGDLPLVADVSSHILSR
CCCCCCCEECCCCCCCEECCCCEEEEEECCCCCCCCEEECCCCCCCCCEEHHHHHHHHHC
PIDVTRYGALFGGAQKNIGMAGVTLVVVREDLLDRALPICPSAFEWKTVAANNSMYNTPP
CCCHHHHHHHHCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCC
TYAIYIAGLVFKWLKAQGGLAAIAARNAEKAALLYDAIDASSFYLNKVEKASRSRMNVPF
CHHHHHHHHHHHHHHCCCCEEEEEECCCCHHEEEEHHHCCCHHHHHHHHHHHHHCCCCCE
FLADETRNEDFLAGAKARGLLQLKGHKSVGGMRASIYNAVPLAGVKALVEYMKEFERAQA
EEECCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA