Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 238026483

GI number: 238026483

Start: 893078

End: 893722

Strand: Reverse

Name: yggV [C]

Synonym: bglu_1g08270

Alternate gene names: 238026483

Gene position: 893722-893078 (Counterclockwise)

Preceding gene: 238026484

Following gene: 238026482

Centisome position: 22.88

GC content: 71.94

Gene sequence:

>645_bases
ATGAGCGGCCACATCGACCCGGCCCGCGGCGGCGGGCCCGCGCCGCTCACGCGCATCGTGCTCGCCTCGAACAACGCCGG
CAAGCTGCGCGAATTCGCGGCGCTGTTCGAGACCGCAGGCATCGAGATCGTCCCGCAGGGCAAGCTCGACGTCCCCGAAG
CCGAGGAGCCGTATCTGACCTTCATCGAGAACGCGCTGACCAAGGCGCGCCACGCCTCGCGCGCGACCGGCCTGCCCGCG
ATCGCCGACGACTCGGGCCTCTGCGTGCGCGCGCTGCGCGGCGCGCCGGGCGTGCATTCGGCGCGCTACGCGCAGCTCGC
CGGGCTGGAGAAGAGCGACGCGGCCAATAACGCGCATCTGGTCGCGCAACTGCAGGGCATCGAAGACCGACGCGCTTACT
ACTGCTGCGTGCTGTCGCTGGTACGGCACCCCGACGATCCCGAGCCGCTGTTCGCCGAGGGCCGCTGGCAGGGCGAGGTG
ATCGACACGCCGCGCGGCGCGAACGGCTTCGGCTACGATCCGCATTTCCTGCTGCCGGCGCTGGGCGCGACCGTCGCCGA
ACTCGATCCGGCCGCGAAGAACGGCATCAGCCATCGCGCGATCGCGCTGCGCGCGCTGCTCGCGCGGCTCGGGGAAGAGG
CGTGA

Upstream 100 bases:

>100_bases
GCGCCGTTTACGCGCGCCGAGATGGACGCGCTGCTCGACCTCGCGCAGAAGGGCATCGGCGAACTGATCGCGCTGCAGAA
AGCCGCGCGGGAAGCGTGAC

Downstream 100 bases:

>100_bases
GCCGGGCCGCCGAGACCGGGCAACGGATCGTCGCGACGTTCGCGTCGCCGGGCAGGGTCCGCCTCAGCGCGCTGCCGCCG
CTCGCGCTCTACATCCACTT

Product: dITP/XTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 214; Mature: 213

Protein sequence:

>214_residues
MSGHIDPARGGGPAPLTRIVLASNNAGKLREFAALFETAGIEIVPQGKLDVPEAEEPYLTFIENALTKARHASRATGLPA
IADDSGLCVRALRGAPGVHSARYAQLAGLEKSDAANNAHLVAQLQGIEDRRAYYCCVLSLVRHPDDPEPLFAEGRWQGEV
IDTPRGANGFGYDPHFLLPALGATVAELDPAAKNGISHRAIALRALLARLGEEA

Sequences:

>Translated_214_residues
MSGHIDPARGGGPAPLTRIVLASNNAGKLREFAALFETAGIEIVPQGKLDVPEAEEPYLTFIENALTKARHASRATGLPA
IADDSGLCVRALRGAPGVHSARYAQLAGLEKSDAANNAHLVAQLQGIEDRRAYYCCVLSLVRHPDDPEPLFAEGRWQGEV
IDTPRGANGFGYDPHFLLPALGATVAELDPAAKNGISHRAIALRALLARLGEEA
>Mature_213_residues
SGHIDPARGGGPAPLTRIVLASNNAGKLREFAALFETAGIEIVPQGKLDVPEAEEPYLTFIENALTKARHASRATGLPAI
ADDSGLCVRALRGAPGVHSARYAQLAGLEKSDAANNAHLVAQLQGIEDRRAYYCCVLSLVRHPDDPEPLFAEGRWQGEVI
DTPRGANGFGYDPHFLLPALGATVAELDPAAKNGISHRAIALRALLARLGEEA

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=197, Percent_Identity=34.5177664974619, Blast_Score=85, Evalue=6e-17,
Organism=Homo sapiens, GI31657144, Length=166, Percent_Identity=35.5421686746988, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1789324, Length=197, Percent_Identity=48.7309644670051, Blast_Score=181, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI17556833, Length=194, Percent_Identity=30.9278350515464, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920712, Length=188, Percent_Identity=33.5106382978723, Blast_Score=81, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22656; Mature: 22525

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGHIDPARGGGPAPLTRIVLASNNAGKLREFAALFETAGIEIVPQGKLDVPEAEEPYLT
CCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHH
FIENALTKARHASRATGLPAIADDSGLCVRALRGAPGVHSARYAQLAGLEKSDAANNAHL
HHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCEE
VAQLQGIEDRRAYYCCVLSLVRHPDDPEPLFAEGRWQGEVIDTPRGANGFGYDPHFLLPA
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEECCCCCCCCCCCCHHHHHHH
LGATVAELDPAAKNGISHRAIALRALLARLGEEA
HCCHHHHCCHHHHCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGHIDPARGGGPAPLTRIVLASNNAGKLREFAALFETAGIEIVPQGKLDVPEAEEPYLT
CCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHH
FIENALTKARHASRATGLPAIADDSGLCVRALRGAPGVHSARYAQLAGLEKSDAANNAHL
HHHHHHHHHHHHHHHCCCCCEECCCCHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCEE
VAQLQGIEDRRAYYCCVLSLVRHPDDPEPLFAEGRWQGEVIDTPRGANGFGYDPHFLLPA
EEEECCCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCEECCCCCCCCCCCCHHHHHHH
LGATVAELDPAAKNGISHRAIALRALLARLGEEA
HCCHHHHCCHHHHCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA