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The map label for this gene is braD [H]

Identifier: 238026428

GI number: 238026428

Start: 826010

End: 827623

Strand: Reverse

Name: braD [H]

Synonym: bglu_1g07630

Alternate gene names: 238026428

Gene position: 827623-826010 (Counterclockwise)

Preceding gene: 238026429

Following gene: 238026427

Centisome position: 21.19

GC content: 71.87

Gene sequence:

>1614_bases
ATGACTCTGCGCCCCCTCCTGCGGCTGCTGCTGGTTTGCGCGGCATGCGCGCTCGGCAGCCCCGCCGCCTTCGCGCTCCA
GGCCGCCGACGCGGCCGCGCTGGCCGGCGACGACTTCGACGCGAAGCTCGCCGCCATCGACCACCTCGCCGCGGCCGACG
ACGCCGCGTCGGTCGCGCTGCTGCACGCGCTCGCCGACGGCGCCGCGCTCGCCACCGACAGCCGCAGGCTGCTGCTGCAG
GCCGACGACGGCAGCACCCGCGACGCGCTCTCGGGCGCCGTGGTGCCGCCCGGCGACGCCCAGCCCGTCACGCTCAACAA
CCTGCTGCGCAGCAAGGTCGCCGGCGCGCTGTCCGGCCTCGCGCTCGCCTCGCCCGATCTCGCCACCCGCACGGCCGCCA
TCGACGCGCTGCTGAAGAATCCGGACGCCTCGGAAAAGCCGCTGATCGACCGTGCCCGCGCGAAGGAAACCGACCCCACG
CTCAAGCACCGGCTCGACGCGCTGTGGGCGATCGCCGCGCTGCACGACGCCGATCCCGCCAAGCGCCTCGAGGCGGTGCA
ACTGGTAGCCGCGCGCCACGATCTCGACATGATCGAGCAACTGCGCCCGCTGGTGGCCAAGCGGCCCGACGGCAGCGACG
CCGAACCCGACGCGCGCGTGCGCGAGGCCGCCCAGCAGGGGCTCGACGCGCTGCACGCGCTGCAGGAGCGCGGCGAGCTC
GCCAGCACGCTGTTCGCGGGGCTCTCGCTCGGCAGCGTGCTGCTGCTCGCCGCGCTGGGCCTCGCCATCACCTACGGCCT
GATCGGCGTGATCAACATGGCGCACGGCGAATTCCTGATGATCGGCGCCTATGCCACCTACGTGGTGCAGACGCTGTTCC
AGCGCTACGCGCCGGGCGCCTTCGACTGGTACCCGCTGGTGGCCATGCCGGCCTCGTTCGCGGCCGCCGCGCTCGTCGGC
ATCGTGCTGGAGCGCAGCGTGCTGCGCCATCTCTACGGCCGTCCGCTCGAAACGCTGCTGGCCACCTTCGGCGTGAGCCT
GATTTTGATCCAGGCCACGCGCATGATCTTCGGGGCGCAGAACGTGCAGGTGGCCAATCCCGCCTGGATGAGCGGCGGCG
TGACGGTGATGCAGAACCTGATCCTGCCGTACAACCGCATCGTAATCCTCGCGTTCTCGCTGGCGGTGGTGGCGGTGGCC
TGGGGCGTGCTGACCCGGACCCGGCTCGGCCTGTTCGTGCGCGCGGTCACGCAGAACCGCCGGATGGCCGCCTGCGTCGG
CGTGAAGACGGCGCGCGTCGATGCCTATGCGTTCGCGTTCGGCGCCGGCATCGCCGGGCTCGGCGGCTGCGCGCTCTCGC
AGATCGGCAACGTCGGCCCCGACCTCGGCCAGAACTACATCATCGATTCGTTCATGGCGGTGGTGCTCGGCGGCGTCGGC
CAGATCGCCGGCACGGTGGTGGGCGGCTTCGGCCTCGGGCTCGTCAGCAAGGCCATCGAGCCGTTCTGGGGCGCCGTGCT
CGCCAAGATCGCCGTGCTCGTGATGATCGTGCTGTTCATCCAGAAGCGCCCGCAGGGCATGTTCGCCCTGAAGGGCCGCA
GCGCGGAGGCTTGA

Upstream 100 bases:

>100_bases
CGCCGCCGCGCCGCCGCGCTCGCGTAACTCGCCACGCCGGGACCTGGGGCGCGCAGTCGGCGCCCTGTCCCGCGATGTCC
TCGCTCGACGGATCCTGCTC

Downstream 100 bases:

>100_bases
CGCGATGACTTCGATCACCTCCTCCCCGCTGGCACCGGCCACGGTGCCCACGCCCGCGCCCGCCGGCGCGCCCGGCTTCG
CGCTCGGCCTGCCGCCGCGC

Product: Branched-chain amino acid ABC transporter permease

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 537; Mature: 536

Protein sequence:

>537_residues
MTLRPLLRLLLVCAACALGSPAAFALQAADAAALAGDDFDAKLAAIDHLAAADDAASVALLHALADGAALATDSRRLLLQ
ADDGSTRDALSGAVVPPGDAQPVTLNNLLRSKVAGALSGLALASPDLATRTAAIDALLKNPDASEKPLIDRARAKETDPT
LKHRLDALWAIAALHDADPAKRLEAVQLVAARHDLDMIEQLRPLVAKRPDGSDAEPDARVREAAQQGLDALHALQERGEL
ASTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLFQRYAPGAFDWYPLVAMPASFAAAALVG
IVLERSVLRHLYGRPLETLLATFGVSLILIQATRMIFGAQNVQVANPAWMSGGVTVMQNLILPYNRIVILAFSLAVVAVA
WGVLTRTRLGLFVRAVTQNRRMAACVGVKTARVDAYAFAFGAGIAGLGGCALSQIGNVGPDLGQNYIIDSFMAVVLGGVG
QIAGTVVGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA

Sequences:

>Translated_537_residues
MTLRPLLRLLLVCAACALGSPAAFALQAADAAALAGDDFDAKLAAIDHLAAADDAASVALLHALADGAALATDSRRLLLQ
ADDGSTRDALSGAVVPPGDAQPVTLNNLLRSKVAGALSGLALASPDLATRTAAIDALLKNPDASEKPLIDRARAKETDPT
LKHRLDALWAIAALHDADPAKRLEAVQLVAARHDLDMIEQLRPLVAKRPDGSDAEPDARVREAAQQGLDALHALQERGEL
ASTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLFQRYAPGAFDWYPLVAMPASFAAAALVG
IVLERSVLRHLYGRPLETLLATFGVSLILIQATRMIFGAQNVQVANPAWMSGGVTVMQNLILPYNRIVILAFSLAVVAVA
WGVLTRTRLGLFVRAVTQNRRMAACVGVKTARVDAYAFAFGAGIAGLGGCALSQIGNVGPDLGQNYIIDSFMAVVLGGVG
QIAGTVVGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA
>Mature_536_residues
TLRPLLRLLLVCAACALGSPAAFALQAADAAALAGDDFDAKLAAIDHLAAADDAASVALLHALADGAALATDSRRLLLQA
DDGSTRDALSGAVVPPGDAQPVTLNNLLRSKVAGALSGLALASPDLATRTAAIDALLKNPDASEKPLIDRARAKETDPTL
KHRLDALWAIAALHDADPAKRLEAVQLVAARHDLDMIEQLRPLVAKRPDGSDAEPDARVREAAQQGLDALHALQERGELA
STLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLFQRYAPGAFDWYPLVAMPASFAAAALVGI
VLERSVLRHLYGRPLETLLATFGVSLILIQATRMIFGAQNVQVANPAWMSGGVTVMQNLILPYNRIVILAFSLAVVAVAW
GVLTRTRLGLFVRAVTQNRRMAACVGVKTARVDAYAFAFGAGIAGLGGCALSQIGNVGPDLGQNYIIDSFMAVVLGGVGQ
IAGTVVGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA

Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]

COG id: COG0559

COG function: function code E; Branched-chain amino acid ABC-type transport system, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789866, Length=314, Percent_Identity=28.343949044586, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851 [H]

Pfam domain/function: PF02653 BPD_transp_2 [H]

EC number: NA

Molecular weight: Translated: 56003; Mature: 55872

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLRPLLRLLLVCAACALGSPAAFALQAADAAALAGDDFDAKLAAIDHLAAADDAASVAL
CCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHH
LHALADGAALATDSRRLLLQADDGSTRDALSGAVVPPGDAQPVTLNNLLRSKVAGALSGL
HHHHHCCCCEECCCCEEEEEECCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALASPDLATRTAAIDALLKNPDASEKPLIDRARAKETDPTLKHRLDALWAIAALHDADPA
HHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHH
KRLEAVQLVAARHDLDMIEQLRPLVAKRPDGSDAEPDARVREAAQQGLDALHALQERGEL
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ASTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLFQRYAPGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCC
FDWYPLVAMPASFAAAALVGIVLERSVLRHLYGRPLETLLATFGVSLILIQATRMIFGAQ
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NVQVANPAWMSGGVTVMQNLILPYNRIVILAFSLAVVAVAWGVLTRTRLGLFVRAVTQNR
CCEECCCCHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RMAACVGVKTARVDAYAFAFGAGIAGLGGCALSQIGNVGPDLGQNYIIDSFMAVVLGGVG
CCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHH
QIAGTVVGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC
>Mature Secondary Structure 
TLRPLLRLLLVCAACALGSPAAFALQAADAAALAGDDFDAKLAAIDHLAAADDAASVAL
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHH
LHALADGAALATDSRRLLLQADDGSTRDALSGAVVPPGDAQPVTLNNLLRSKVAGALSGL
HHHHHCCCCEECCCCEEEEEECCCCCHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALASPDLATRTAAIDALLKNPDASEKPLIDRARAKETDPTLKHRLDALWAIAALHDADPA
HHCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHH
KRLEAVQLVAARHDLDMIEQLRPLVAKRPDGSDAEPDARVREAAQQGLDALHALQERGEL
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
ASTLFAGLSLGSVLLLAALGLAITYGLIGVINMAHGEFLMIGAYATYVVQTLFQRYAPGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCC
FDWYPLVAMPASFAAAALVGIVLERSVLRHLYGRPLETLLATFGVSLILIQATRMIFGAQ
CCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCC
NVQVANPAWMSGGVTVMQNLILPYNRIVILAFSLAVVAVAWGVLTRTRLGLFVRAVTQNR
CCEECCCCHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
RMAACVGVKTARVDAYAFAFGAGIAGLGGCALSQIGNVGPDLGQNYIIDSFMAVVLGGVG
CCHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCHH
QIAGTVVGGFGLGLVSKAIEPFWGAVLAKIAVLVMIVLFIQKRPQGMFALKGRSAEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2120183; 10984043; 2509433 [H]