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The map label for this gene is livM [H]

Identifier: 238026427

GI number: 238026427

Start: 824827

End: 826005

Strand: Reverse

Name: livM [H]

Synonym: bglu_1g07620

Alternate gene names: 238026427

Gene position: 826005-824827 (Counterclockwise)

Preceding gene: 238026428

Following gene: 238026426

Centisome position: 21.14

GC content: 69.3

Gene sequence:

>1179_bases
ATGACTTCGATCACCTCCTCCCCGCTGGCACCGGCCACGGTGCCCACGCCCGCGCCCGCCGGCGCGCCCGGCTTCGCGCT
CGGCCTGCCGCCGCGCGCGGCGCTGCTCTCGCGCCGCGCCTGGCTCGCGCTCGTCGCGCTGTGCCTGGCGATCGGCGTCG
GCGTGCCGCTCGCCGCGCTGGTCGCGCCCGAGACGAGCGCGTTCCACCTGTCGGCCTATGCCATGACGATCGCCGGCAAG
TTCATGTGCTACGCGATCGGCGCGCTCGCGCTCGACCTGGTGTGGGGCTACTGCGGCATCCTGAGCCTCGGCCACGGCCT
GTTCTTCGCGCTCGGCGGCTACGCGATCGGCATGTACCTGATGCGCGAAATCGGCCACGACGGCGTGTACGGCAGCAGCC
TGCCCGACTTCATGGTGTTCCTGAACTGGAAGTCGCTGCCGTGGTACTGGCACGGCTCCGATCATCTGGCCGTCGCGCTC
GCGCTGGTGGTGCTCGCGCCCGCCGTGGTGGCCTGGGTGTTCGGCTTCTTCACGTTCCGCTCGCGCGTGAAGGGCGTGTA
CCTGTCGATCATCACGCAGGCCATGACGTTCGCCGCCATGCTGCTGTTCTACCGCAACGAGACCGGCTTCGGCGGCAACA
ACGGCTTCACCGACTTCAAGCGCATCGCCGGCTTCGGCATCACCTCGCCCGGCACGCGCACGGTGCTGCTGCTGCTGACC
TTCGCCACCCTGGTGCTGGCCTTCGTGGCCGCGCGCGCGATCGTCACCTCCAAGCTCGGCCGCGTGGTCACCGCCGTGCG
CGACGGCGAAACGCGCCTGATGTTCCTCGGCTACAGCCCGCTCGCCTACAAGCTGTTCGTGTGGACCGTGTCGGCGGTGC
TGTGCGGCATCGCCGGCGCCCTGTACGTGCCGCAGGTCGGCATCATCAATCCCGGCGAGATGTCGCCGGGCAACTCGATC
GAGATGGCGATCTGGGTGGCCGTGGGCGGGCGCGGCACGCTGATCGGGCCGATCCTCGGCGCGTTTGCCGTGAACGGCGC
GAAGAGCTTCTTCACCGCCTACTTCGCCGAATACTGGCTGTTCTTCCTCGGCCTGATCTTCGTGCTGGTGCCGCTCTTGA
TGCCGCGCGGCATCGTCGGCCTGGCCGATTCCCTCCTGAAGCGCGGAGCACGCCGATGA

Upstream 100 bases:

>100_bases
CTCGCCAAGATCGCCGTGCTCGTGATGATCGTGCTGTTCATCCAGAAGCGCCCGCAGGGCATGTTCGCCCTGAAGGGCCG
CAGCGCGGAGGCTTGACGCG

Downstream 100 bases:

>100_bases
GCACGCACGCCACCGCCCTCGCCGTGAGCGGCGTGGCCTCGATGGCGCGCGTGGTCGAGCCGGGCGCGATCGACACCTCG
CACGGCACGATCCTCTACCT

Product: branched chain amino acid family ABC transporter inner membrane subunit

Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]

Alternate protein names: LIV-I protein M [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MTSITSSPLAPATVPTPAPAGAPGFALGLPPRAALLSRRAWLALVALCLAIGVGVPLAALVAPETSAFHLSAYAMTIAGK
FMCYAIGALALDLVWGYCGILSLGHGLFFALGGYAIGMYLMREIGHDGVYGSSLPDFMVFLNWKSLPWYWHGSDHLAVAL
ALVVLAPAVVAWVFGFFTFRSRVKGVYLSIITQAMTFAAMLLFYRNETGFGGNNGFTDFKRIAGFGITSPGTRTVLLLLT
FATLVLAFVAARAIVTSKLGRVVTAVRDGETRLMFLGYSPLAYKLFVWTVSAVLCGIAGALYVPQVGIINPGEMSPGNSI
EMAIWVAVGGRGTLIGPILGAFAVNGAKSFFTAYFAEYWLFFLGLIFVLVPLLMPRGIVGLADSLLKRGARR

Sequences:

>Translated_392_residues
MTSITSSPLAPATVPTPAPAGAPGFALGLPPRAALLSRRAWLALVALCLAIGVGVPLAALVAPETSAFHLSAYAMTIAGK
FMCYAIGALALDLVWGYCGILSLGHGLFFALGGYAIGMYLMREIGHDGVYGSSLPDFMVFLNWKSLPWYWHGSDHLAVAL
ALVVLAPAVVAWVFGFFTFRSRVKGVYLSIITQAMTFAAMLLFYRNETGFGGNNGFTDFKRIAGFGITSPGTRTVLLLLT
FATLVLAFVAARAIVTSKLGRVVTAVRDGETRLMFLGYSPLAYKLFVWTVSAVLCGIAGALYVPQVGIINPGEMSPGNSI
EMAIWVAVGGRGTLIGPILGAFAVNGAKSFFTAYFAEYWLFFLGLIFVLVPLLMPRGIVGLADSLLKRGARR
>Mature_391_residues
TSITSSPLAPATVPTPAPAGAPGFALGLPPRAALLSRRAWLALVALCLAIGVGVPLAALVAPETSAFHLSAYAMTIAGKF
MCYAIGALALDLVWGYCGILSLGHGLFFALGGYAIGMYLMREIGHDGVYGSSLPDFMVFLNWKSLPWYWHGSDHLAVALA
LVVLAPAVVAWVFGFFTFRSRVKGVYLSIITQAMTFAAMLLFYRNETGFGGNNGFTDFKRIAGFGITSPGTRTVLLLLTF
ATLVLAFVAARAIVTSKLGRVVTAVRDGETRLMFLGYSPLAYKLFVWTVSAVLCGIAGALYVPQVGIINPGEMSPGNSIE
MAIWVAVGGRGTLIGPILGAFAVNGAKSFFTAYFAEYWLFFLGLIFVLVPLLMPRGIVGLADSLLKRGARR

Specific function: Part of the binding-protein-dependent transport system for branched-chain amino acids. Probably responsible for the translocation of the substrates across the membrane [H]

COG id: COG4177

COG function: function code E; ABC-type branched-chain amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. LivHM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789865, Length=342, Percent_Identity=26.6081871345029, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001851
- InterPro:   IPR021807 [H]

Pfam domain/function: PF02653 BPD_transp_2; PF11862 DUF3382 [H]

EC number: NA

Molecular weight: Translated: 41658; Mature: 41527

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSITSSPLAPATVPTPAPAGAPGFALGLPPRAALLSRRAWLALVALCLAIGVGVPLAAL
CCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VAPETSAFHLSAYAMTIAGKFMCYAIGALALDLVWGYCGILSLGHGLFFALGGYAIGMYL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MREIGHDGVYGSSLPDFMVFLNWKSLPWYWHGSDHLAVALALVVLAPAVVAWVFGFFTFR
HHHHCCCCCCCCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRVKGVYLSIITQAMTFAAMLLFYRNETGFGGNNGFTDFKRIAGFGITSPGTRTVLLLLT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHH
FATLVLAFVAARAIVTSKLGRVVTAVRDGETRLMFLGYSPLAYKLFVWTVSAVLCGIAGA
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
LYVPQVGIINPGEMSPGNSIEMAIWVAVGGRGTLIGPILGAFAVNGAKSFFTAYFAEYWL
HHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
FFLGLIFVLVPLLMPRGIVGLADSLLKRGARR
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TSITSSPLAPATVPTPAPAGAPGFALGLPPRAALLSRRAWLALVALCLAIGVGVPLAAL
CCCCCCCCCCCCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
VAPETSAFHLSAYAMTIAGKFMCYAIGALALDLVWGYCGILSLGHGLFFALGGYAIGMYL
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MREIGHDGVYGSSLPDFMVFLNWKSLPWYWHGSDHLAVALALVVLAPAVVAWVFGFFTFR
HHHHCCCCCCCCCCCCCEEEEECCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRVKGVYLSIITQAMTFAAMLLFYRNETGFGGNNGFTDFKRIAGFGITSPGTRTVLLLLT
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHH
FATLVLAFVAARAIVTSKLGRVVTAVRDGETRLMFLGYSPLAYKLFVWTVSAVLCGIAGA
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHH
LYVPQVGIINPGEMSPGNSIEMAIWVAVGGRGTLIGPILGAFAVNGAKSFFTAYFAEYWL
HHCCCCCCCCCCCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHH
FFLGLIFVLVPLLMPRGIVGLADSLLKRGARR
HHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]

Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2195019; 8041620; 9278503 [H]