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The map label for this gene is acdA [H]

Identifier: 238026355

GI number: 238026355

Start: 740882

End: 742069

Strand: Reverse

Name: acdA [H]

Synonym: bglu_1g06890

Alternate gene names: 238026355

Gene position: 742069-740882 (Counterclockwise)

Preceding gene: 238026357

Following gene: 238026353

Centisome position: 19.0

GC content: 67.68

Gene sequence:

>1188_bases
ATGAGCACCACCGCTTTCCAATGGGACGATCCGCTGCTGCTCGACCAGCAGCTAAGCGACGACGAGCGGATGATCCGCGA
CGCGGCCCGCGCCTATGCGCAGGGCAAGCTCGCGCCGCGCGTGGTCGAGGCGTTCCGCCACGAGAAGACCGACACGACGA
TCTTCCGCGAGATGGGTGAGATCGGGCTGCTCGGCCCGACGATTCCCGAGCAGTACGGCGGCCCGGGCCTCAACTACGTC
AGCTACGGGCTGATCGCGCGCGAGGTGGAGCGCATCGATTCGGGCTACCGCTCGATGATGTCGGTGCAGTCGTCGCTGGT
GATGGTGCCGATCAACGCGTTCGGCTCCGAGGCGCAGAAGCAGAAATACCTGCCCAAGCTCGCCAGCGGCGAATGGATCG
GCTGCTTCGGGCTGACCGAGCCTGACCACGGCTCGGACCCGGGCGGCATGAGCACGCGCGCGAAGCCGGTGCCGGGCGGC
TACGTGCTGTCGGGTGCGAAGATGTGGATCACCAATTCGCCGATCGCCGATGTGTTCATCGTGTGGGCCAAGCTCGAGGA
AAACGGCGAGGACGCGATCCGCGGCTTCATTCTCGAGAAGGGCTGGAAGGGGCTGTCGGCGCCGGCGATTCACGGCAAGG
TCGGGCTGCGCGCCTCGATCACCGGCGAGATCGTGCTCGACGAGGTGTTCGTGCCCGAGGAAAACCGCCTGCCCGGCGTG
AAGGGGCTGCGCGGCCCGTTCACCTGCCTCGACTCGGCGCGCTACGGCATTTCGTGGGGCGCGCTCGGCGCGGCCGAATC
GTGCTGGCACACGGCGCGCCAGTACGTGCTCGACCGCAAGCAGTTCGGGCGCCCGCTCGCGGCCAACCAGCTGATCCAGA
AGAAGCTCGCCGACATGCAGACCGAGATCACGCTGGGCCTGCAGGGGGTGCTGCGGCTCGGCCGCATGAAGGACGAAGGC
ACGGCCGCCGTCGAGATCACCTCGATCATGAAGCGCAACTCGTGCGGCAAGGCGCTCGAGGTGGCGCGGCTCGCGCGCGA
CATGCTCGGCGGCAACGGCATCTCGGACGAATTCGGCGTGGCGCGCCACCTGGTCAACCTCGAGGTCGTCAACACCTACG
AGGGCACCCACGACATCCACGCGCTGATCCTCGGCCGCGCGCAGACAGGCATCCAGGCGTTCTCGTGA

Upstream 100 bases:

>100_bases
CGTCGATACGGGCGAAATTCGACACGGTGTACACTCAATCTCAAAATTGCAAAACATTGTTCCGCAGTGCGGAACTCCAG
TCAAGCAAGGAGCCGACACG

Downstream 100 bases:

>100_bases
CCCCGGCCCGCCCTCAGGCGCTAGGCCCGGCCCCGCCGCCGGCAGGCGCCATGCAAAACGGGCAGCGCGATCGGCGATGC
CCGTTGCGGTTGGTGCGGCC

Product: acyl-CoA dehydrogenase-like protein

Products: crotonoyl-CoA; CO2; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 395; Mature: 394

Protein sequence:

>395_residues
MSTTAFQWDDPLLLDQQLSDDERMIRDAARAYAQGKLAPRVVEAFRHEKTDTTIFREMGEIGLLGPTIPEQYGGPGLNYV
SYGLIAREVERIDSGYRSMMSVQSSLVMVPINAFGSEAQKQKYLPKLASGEWIGCFGLTEPDHGSDPGGMSTRAKPVPGG
YVLSGAKMWITNSPIADVFIVWAKLEENGEDAIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENRLPGV
KGLRGPFTCLDSARYGISWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEG
TAAVEITSIMKRNSCGKALEVARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFS

Sequences:

>Translated_395_residues
MSTTAFQWDDPLLLDQQLSDDERMIRDAARAYAQGKLAPRVVEAFRHEKTDTTIFREMGEIGLLGPTIPEQYGGPGLNYV
SYGLIAREVERIDSGYRSMMSVQSSLVMVPINAFGSEAQKQKYLPKLASGEWIGCFGLTEPDHGSDPGGMSTRAKPVPGG
YVLSGAKMWITNSPIADVFIVWAKLEENGEDAIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENRLPGV
KGLRGPFTCLDSARYGISWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEG
TAAVEITSIMKRNSCGKALEVARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFS
>Mature_394_residues
STTAFQWDDPLLLDQQLSDDERMIRDAARAYAQGKLAPRVVEAFRHEKTDTTIFREMGEIGLLGPTIPEQYGGPGLNYVS
YGLIAREVERIDSGYRSMMSVQSSLVMVPINAFGSEAQKQKYLPKLASGEWIGCFGLTEPDHGSDPGGMSTRAKPVPGGY
VLSGAKMWITNSPIADVFIVWAKLEENGEDAIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENRLPGVK
GLRGPFTCLDSARYGISWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQTEITLGLQGVLRLGRMKDEGT
AAVEITSIMKRNSCGKALEVARLARDMLGGNGISDEFGVARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFS

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4503943, Length=396, Percent_Identity=64.8989898989899, Blast_Score=521, Evalue=1e-148,
Organism=Homo sapiens, GI7669494, Length=375, Percent_Identity=63.4666666666667, Blast_Score=482, Evalue=1e-136,
Organism=Homo sapiens, GI226958412, Length=376, Percent_Identity=34.3085106382979, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI4557233, Length=372, Percent_Identity=31.7204301075269, Blast_Score=192, Evalue=4e-49,
Organism=Homo sapiens, GI226958414, Length=344, Percent_Identity=34.593023255814, Blast_Score=190, Evalue=2e-48,
Organism=Homo sapiens, GI4501859, Length=367, Percent_Identity=28.8828337874659, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI4557235, Length=347, Percent_Identity=33.1412103746398, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI76496475, Length=347, Percent_Identity=33.1412103746398, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI4557231, Length=375, Percent_Identity=30.1333333333333, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI187960098, Length=375, Percent_Identity=30.1333333333333, Blast_Score=162, Evalue=6e-40,
Organism=Homo sapiens, GI21361497, Length=372, Percent_Identity=31.7204301075269, Blast_Score=153, Evalue=2e-37,
Organism=Homo sapiens, GI7656849, Length=381, Percent_Identity=28.0839895013123, Blast_Score=149, Evalue=3e-36,
Organism=Homo sapiens, GI4501857, Length=383, Percent_Identity=28.9817232375979, Blast_Score=137, Evalue=3e-32,
Organism=Escherichia coli, GI1786223, Length=390, Percent_Identity=24.1025641025641, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87081958, Length=333, Percent_Identity=27.6276276276276, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17534353, Length=397, Percent_Identity=62.9722921914358, Blast_Score=504, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17538396, Length=388, Percent_Identity=33.2474226804124, Blast_Score=194, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI17508101, Length=367, Percent_Identity=33.2425068119891, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17506239, Length=365, Percent_Identity=30.4109589041096, Blast_Score=171, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI17569725, Length=375, Percent_Identity=30.6666666666667, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=29.7872340425532, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71985184, Length=369, Percent_Identity=30.6233062330623, Blast_Score=158, Evalue=6e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=274, Percent_Identity=34.6715328467153, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17570075, Length=379, Percent_Identity=27.7044854881267, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71985192, Length=296, Percent_Identity=31.0810810810811, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=30.7692307692308, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=33.3333333333333, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17533517, Length=373, Percent_Identity=24.1286863270777, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17551932, Length=362, Percent_Identity=24.3093922651934, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17505929, Length=359, Percent_Identity=25.0696378830084, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI19920834, Length=394, Percent_Identity=60.4060913705584, Blast_Score=477, Evalue=1e-135,
Organism=Drosophila melanogaster, GI21356377, Length=371, Percent_Identity=32.8840970350404, Blast_Score=208, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24646207, Length=372, Percent_Identity=33.0645161290323, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24666513, Length=365, Percent_Identity=32.0547945205479, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21355753, Length=375, Percent_Identity=31.7333333333333, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24660351, Length=378, Percent_Identity=30.6878306878307, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI281363737, Length=411, Percent_Identity=31.1435523114355, Blast_Score=163, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.7

Molecular weight: Translated: 43067; Mature: 42936

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTAFQWDDPLLLDQQLSDDERMIRDAARAYAQGKLAPRVVEAFRHEKTDTTIFREMGE
CCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCC
IGLLGPTIPEQYGGPGLNYVSYGLIAREVERIDSGYRSMMSVQSSLVMVPINAFGSEAQK
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHCCCHHHH
QKYLPKLASGEWIGCFGLTEPDHGSDPGGMSTRAKPVPGGYVLSGAKMWITNSPIADVFI
HHHCCHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCHHHHEE
VWAKLEENGEDAIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENRLPGV
EEEHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCC
KGLRGPFTCLDSARYGISWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQ
CCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALEVARLARDMLGGNGISDEFGV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHH
ARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFS
HHHHHEEEEEECCCCCHHEEHHEEECHHCCCCCCC
>Mature Secondary Structure 
STTAFQWDDPLLLDQQLSDDERMIRDAARAYAQGKLAPRVVEAFRHEKTDTTIFREMGE
CCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHCC
IGLLGPTIPEQYGGPGLNYVSYGLIAREVERIDSGYRSMMSVQSSLVMVPINAFGSEAQK
CCCCCCCCCHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEHHHCCCHHHH
QKYLPKLASGEWIGCFGLTEPDHGSDPGGMSTRAKPVPGGYVLSGAKMWITNSPIADVFI
HHHCCHHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCEEEEECCCHHHHEE
VWAKLEENGEDAIRGFILEKGWKGLSAPAIHGKVGLRASITGEIVLDEVFVPEENRLPGV
EEEHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCEEECCCEEEEEEEECCCCCCCCCC
KGLRGPFTCLDSARYGISWGALGAAESCWHTARQYVLDRKQFGRPLAANQLIQKKLADMQ
CCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
TEITLGLQGVLRLGRMKDEGTAAVEITSIMKRNSCGKALEVARLARDMLGGNGISDEFGV
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHH
ARHLVNLEVVNTYEGTHDIHALILGRAQTGIQAFS
HHHHHEEEEEECCCCCHHEEHHEEECHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: glutaryl-CoA; acceptor

Specific reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]