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The map label for this gene is yafV [C]

Identifier: 238026290

GI number: 238026290

Start: 659070

End: 659909

Strand: Reverse

Name: yafV [C]

Synonym: bglu_1g06240

Alternate gene names: 238026290

Gene position: 659909-659070 (Counterclockwise)

Preceding gene: 238026291

Following gene: 238026289

Centisome position: 16.89

GC content: 72.38

Gene sequence:

>840_bases
ATGACCGACCGATCCGAACGCCTCGCCCCGCTGACGGTCGCCGCCGTGCAGATGGTCAGCTCGCCCGATCTCGCCCGCAA
CCTGGACGACGCGGGCCGGCTGGTCGCCGAGGCGGCCGCGCTCGGCGCGAAGCTCGTGCTGCTGCCGGAATACTTCTGCT
TCATGGGCCGGCGCGACACCGACAAGCTCGCGCTCGCCGAACCCTATCAGGACGGCCCGATCCAGCGCTTCCTCGCCGAT
TGCGCGCGCCGCCACGGCGTCTGGCTGATCGGCGGCACGCTGCCGCTCGCCGCGCCCGAGCCGTCGCGCGTGCTGAACAC
CACGCTGGTGTTCGGTCCCGACGGGCGCGAATGCGCGCGCTACGACAAGATCCACCTGTTCAGCTTCGAGAAGGACGGCG
AATCGTTCGACGAGGCCCGCACGATCCGCCCAGGCGGCACCGACGCCTCGGCGGTGCGCGGCTTCGAGGCGCCGTTCGGC
CGGGTCGGCCTGTCGGTCTGCTACGATCTGCGCTTTCCGGAGCTGTATCGCCGCCTCGGCGACTGCGCGCTGATCGTCGT
GCCGTCCGCGTTCACCTACACCACCGGCCGCGCGCACTGGGAGACGCTGCTGCGCGCGCGGGCGATCGAGAACCAGTGCT
ACGTGCTCGCCGCCGCGCAGGGCGGCCGCCATGAGAACGGCCGGCGCACCTGGGGACACAGCATGCTGGTGGACCCGTGG
GGCGAGATCGTCGCCGTGCGCGACGAAAGCCCCGGCGTGGTGGCCGGCACGGTCGATCCGGCGCGCCTGGCCGAAGTCCG
CCAGAGCCTGCCCGCCTGGCGCCACCGCGTGCTCGACTGA

Upstream 100 bases:

>100_bases
CGGGTCGCGGACGATCGGGGTAAGATGGGCCGCATGCCCGCCGATGCGGCCCGTCCCTGACGGTGCGGGACGCACCCTTT
TTTACGTCCGACGCTCTCCG

Downstream 100 bases:

>100_bases
GCGCCCCGCCGAGCCCACGCGATCCGCTCCGAAACCGACACACCGACGACACACCCGACCCCGCTCAAAGCAACCCCGAT
ATCCGATACCGCATGAACAT

Product: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 279; Mature: 278

Protein sequence:

>279_residues
MTDRSERLAPLTVAAVQMVSSPDLARNLDDAGRLVAEAAALGAKLVLLPEYFCFMGRRDTDKLALAEPYQDGPIQRFLAD
CARRHGVWLIGGTLPLAAPEPSRVLNTTLVFGPDGRECARYDKIHLFSFEKDGESFDEARTIRPGGTDASAVRGFEAPFG
RVGLSVCYDLRFPELYRRLGDCALIVVPSAFTYTTGRAHWETLLRARAIENQCYVLAAAQGGRHENGRRTWGHSMLVDPW
GEIVAVRDESPGVVAGTVDPARLAEVRQSLPAWRHRVLD

Sequences:

>Translated_279_residues
MTDRSERLAPLTVAAVQMVSSPDLARNLDDAGRLVAEAAALGAKLVLLPEYFCFMGRRDTDKLALAEPYQDGPIQRFLAD
CARRHGVWLIGGTLPLAAPEPSRVLNTTLVFGPDGRECARYDKIHLFSFEKDGESFDEARTIRPGGTDASAVRGFEAPFG
RVGLSVCYDLRFPELYRRLGDCALIVVPSAFTYTTGRAHWETLLRARAIENQCYVLAAAQGGRHENGRRTWGHSMLVDPW
GEIVAVRDESPGVVAGTVDPARLAEVRQSLPAWRHRVLD
>Mature_278_residues
TDRSERLAPLTVAAVQMVSSPDLARNLDDAGRLVAEAAALGAKLVLLPEYFCFMGRRDTDKLALAEPYQDGPIQRFLADC
ARRHGVWLIGGTLPLAAPEPSRVLNTTLVFGPDGRECARYDKIHLFSFEKDGESFDEARTIRPGGTDASAVRGFEAPFGR
VGLSVCYDLRFPELYRRLGDCALIVVPSAFTYTTGRAHWETLLRARAIENQCYVLAAAQGGRHENGRRTWGHSMLVDPWG
EIVAVRDESPGVVAGTVDPARLAEVRQSLPAWRHRVLD

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632348, Length=270, Percent_Identity=41.4814814814815, Blast_Score=191, Evalue=5e-49,
Organism=Homo sapiens, GI297632350, Length=270, Percent_Identity=41.4814814814815, Blast_Score=191, Evalue=5e-49,
Organism=Homo sapiens, GI5031947, Length=273, Percent_Identity=41.3919413919414, Blast_Score=191, Evalue=6e-49,
Organism=Homo sapiens, GI9910460, Length=276, Percent_Identity=37.3188405797101, Blast_Score=184, Evalue=9e-47,
Organism=Homo sapiens, GI297632346, Length=195, Percent_Identity=36.4102564102564, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1786412, Length=236, Percent_Identity=31.3559322033898, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17556280, Length=270, Percent_Identity=39.6296296296296, Blast_Score=193, Evalue=8e-50,
Organism=Saccharomyces cerevisiae, GI6323383, Length=280, Percent_Identity=34.2857142857143, Blast_Score=168, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6322335, Length=309, Percent_Identity=33.0097087378641, Blast_Score=161, Evalue=8e-41,
Organism=Drosophila melanogaster, GI17933642, Length=270, Percent_Identity=37.7777777777778, Blast_Score=178, Evalue=4e-45,
Organism=Drosophila melanogaster, GI21355835, Length=275, Percent_Identity=32.7272727272727, Blast_Score=148, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 30747; Mature: 30616

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRSERLAPLTVAAVQMVSSPDLARNLDDAGRLVAEAAALGAKLVLLPEYFCFMGRRDT
CCCCCHHCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCEEEEHHHHHHHCCCCCC
DKLALAEPYQDGPIQRFLADCARRHGVWLIGGTLPLAAPEPSRVLNTTLVFGPDGRECAR
CCEEEECCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEEECCCCHHHHC
YDKIHLFSFEKDGESFDEARTIRPGGTDASAVRGFEAPFGRVGLSVCYDLRFPELYRRLG
CCEEEEEEECCCCCCHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHEECCCHHHHHHHC
DCALIVVPSAFTYTTGRAHWETLLRARAIENQCYVLAAAQGGRHENGRRTWGHSMLVDPW
CEEEEEECCCEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEECCC
GEIVAVRDESPGVVAGTVDPARLAEVRQSLPAWRHRVLD
CCEEEEECCCCCEEEECCCHHHHHHHHHHCHHHHHHCCC
>Mature Secondary Structure 
TDRSERLAPLTVAAVQMVSSPDLARNLDDAGRLVAEAAALGAKLVLLPEYFCFMGRRDT
CCCCHHCCHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHCCEEEEHHHHHHHCCCCCC
DKLALAEPYQDGPIQRFLADCARRHGVWLIGGTLPLAAPEPSRVLNTTLVFGPDGRECAR
CCEEEECCCCCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEEECCCCHHHHC
YDKIHLFSFEKDGESFDEARTIRPGGTDASAVRGFEAPFGRVGLSVCYDLRFPELYRRLG
CCEEEEEEECCCCCCHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHEECCCHHHHHHHC
DCALIVVPSAFTYTTGRAHWETLLRARAIENQCYVLAAAQGGRHENGRRTWGHSMLVDPW
CEEEEEECCCEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEECCC
GEIVAVRDESPGVVAGTVDPARLAEVRQSLPAWRHRVLD
CCEEEEECCCCCEEEECCCHHHHHHHHHHCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]