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The map label for this gene is tldD [H]

Identifier: 238026289

GI number: 238026289

Start: 657511

End: 658977

Strand: Reverse

Name: tldD [H]

Synonym: bglu_1g06230

Alternate gene names: 238026289

Gene position: 658977-657511 (Counterclockwise)

Preceding gene: 238026290

Following gene: 238026288

Centisome position: 16.87

GC content: 69.53

Gene sequence:

>1467_bases
ATGAACATCATCGAACCCGGCATCCGCAATCTCGCCCTCGCCAAGGACATCCTGCTCACGCCGTACGGCCTCGACGAAAC
GCTGCTCACGCGCACGCTCGCCGACATCTTCACGCATCGCGTCGACTACGCGGACCTGTACTTCCAGGCGACCCGCAGCG
AAGCGTGGAGCCTGGAGGAAGGAATCGTGAAATCGGGCAGCTTCAGCATCGACCAGGGCGTCGGCGTGCGGGCCGTGGCC
GGCGAGCGCACCGCGTTCGCCTATTCGGACGACCTCTCGCCCGAGGCGATCCGCCAGGCCGCCAGCGCCACCAAGGCGAT
CGCGGCCGCGGGCGGCGGACGCCGCAGGATCCAGGTGGCATCGTCGCTGACCGGCGTGGCGGGGCGCGACCTCTACCTGC
CGTCCGACCCGCTCGCCTCGCTCGACGCCACCGCCAAGGTCAAGCTGCTCGAACGCGTCGAGCAGATGGCACGCGGCCGC
GACCCGCGCATCACGCAGGTGATGGCGGGCCTGGCCGGCGAATACGACGTGGTGCTGGTGGCGCGCAGCGACGGCGCGCT
GGCCGCCGACATCCGCCCGCTGGTGCGGGTCTCGGTGACGGTGATCGCCGAGCAGGACGGGCGCCGCGAGATCGGCTCGG
GCGGCGGCGGCGGCCGCTTCGACTACGGCTACTTCAGCGACGAGGTGCTGTCGCGCTACGTGGACGACGCCGTCCACGCC
GCGCTCGTCAATCTGGACGCGCGCCCGGCGCCGGCCGGCGCGATGACGGTGGTGCTCGGCTCGGGCTGGCCCGGTGTGCT
GCTGCACGAGGCGATCGGCCATGGCCTGGAGGGCGACTTCAACCGCAAGGGCTCGTCGGCGTTCGCCGGACGCATCGGCG
AGCGCGTCGCCGCCAAGGGCGTGACGGTGGTGGACGACGGCACGCTGCCGAACCGCCGCGGCTCGCTCAACATCGACGAC
GAAGGCAACCCGACCCAGTGCACCACGCTGATCGAGGACGGGATCCTGAAGGGCTACATCCAGGACACGCTGAACGCGCG
CCTCATGAAGATGCCCGTGACCGGCAACGCGCGCCGCGAGTCGTACGCGGCGCTGCCGATGCCGCGCATGACCAACACCT
ACATGCTGAACGGCGACAAGGACCCGCAGGAGATCATCGCATCGGTCAAGCACGGCCTGTACGCGGTGAATTTCGGCGGC
GGCCAGGTCGACATCACCAACGGCAAGTTCGTGTTCTCGGCCTCCGAGGCCTACATGATCGAGAACGGCAAGGTGACCTA
TCCGGTGAAGGGCGCCACGCTGATCGGCAGCGGCCCCGAGTCGCTGAAGTACGTCAGCATGATCGGCAACGACATGAAGC
TCGACTCGGGCGTGGGCGTGTGCGGCAAGGAAGGCCAGAGCGTGCCGGTGGGCGTGGGCCAGCCGACGCTGCGGATCGAC
TCGATGACGGTCGGCGGCACCGCCTGA

Upstream 100 bases:

>100_bases
TCGACTGAGCGCCCCGCCGAGCCCACGCGATCCGCTCCGAAACCGACACACCGACGACACACCCGACCCCGCTCAAAGCA
ACCCCGATATCCGATACCGC

Downstream 100 bases:

>100_bases
GTCCGGCCGGGCGGTCACGCTGCGGCGCGGCAATTCCGCACCGCAGCGCGGACATCGCGCACCAGACATCAACCTTGCGC
GGATTGTCCGCGTTTTTTGC

Product: peptidase U62, modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MNIIEPGIRNLALAKDILLTPYGLDETLLTRTLADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSIDQGVGVRAVA
GERTAFAYSDDLSPEAIRQAASATKAIAAAGGGRRRIQVASSLTGVAGRDLYLPSDPLASLDATAKVKLLERVEQMARGR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQDGRREIGSGGGGGRFDYGYFSDEVLSRYVDDAVHA
ALVNLDARPAPAGAMTVVLGSGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGERVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKHGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMKLDSGVGVCGKEGQSVPVGVGQPTLRID
SMTVGGTA

Sequences:

>Translated_488_residues
MNIIEPGIRNLALAKDILLTPYGLDETLLTRTLADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSIDQGVGVRAVA
GERTAFAYSDDLSPEAIRQAASATKAIAAAGGGRRRIQVASSLTGVAGRDLYLPSDPLASLDATAKVKLLERVEQMARGR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQDGRREIGSGGGGGRFDYGYFSDEVLSRYVDDAVHA
ALVNLDARPAPAGAMTVVLGSGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGERVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKHGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMKLDSGVGVCGKEGQSVPVGVGQPTLRID
SMTVGGTA
>Mature_488_residues
MNIIEPGIRNLALAKDILLTPYGLDETLLTRTLADIFTHRVDYADLYFQATRSEAWSLEEGIVKSGSFSIDQGVGVRAVA
GERTAFAYSDDLSPEAIRQAASATKAIAAAGGGRRRIQVASSLTGVAGRDLYLPSDPLASLDATAKVKLLERVEQMARGR
DPRITQVMAGLAGEYDVVLVARSDGALAADIRPLVRVSVTVIAEQDGRREIGSGGGGGRFDYGYFSDEVLSRYVDDAVHA
ALVNLDARPAPAGAMTVVLGSGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGERVAAKGVTVVDDGTLPNRRGSLNIDD
EGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRESYAALPMPRMTNTYMLNGDKDPQEIIASVKHGLYAVNFGG
GQVDITNGKFVFSASEAYMIENGKVTYPVKGATLIGSGPESLKYVSMIGNDMKLDSGVGVCGKEGQSVPVGVGQPTLRID
SMTVGGTA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=484, Percent_Identity=59.0909090909091, Blast_Score=550, Evalue=1e-158,
Organism=Escherichia coli, GI1790682, Length=444, Percent_Identity=24.5495495495495, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51575; Mature: 51575

Theoretical pI: Translated: 5.22; Mature: 5.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIIEPGIRNLALAKDILLTPYGLDETLLTRTLADIFTHRVDYADLYFQATRSEAWSLEE
CCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHHEEEECCCHHHCHHH
GIVKSGSFSIDQGVGVRAVAGERTAFAYSDDLSPEAIRQAASATKAIAAAGGGRRRIQVA
HHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
SSLTGVAGRDLYLPSDPLASLDATAKVKLLERVEQMARGRDPRITQVMAGLAGEYDVVLV
HHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEE
ARSDGALAADIRPLVRVSVTVIAEQDGRREIGSGGGGGRFDYGYFSDEVLSRYVDDAVHA
ECCCCCEECCCCCEEEEEEEEEECCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALVNLDARPAPAGAMTVVLGSGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGERVAAKG
HHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRE
CEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SYAALPMPRMTNTYMLNGDKDPQEIIASVKHGLYAVNFGGGQVDITNGKFVFSASEAYMI
CEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEE
ENGKVTYPVKGATLIGSGPESLKYVSMIGNDMKLDSGVGVCGKEGQSVPVGVGQPTLRID
ECCEEEEEECCCEEECCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEE
SMTVGGTA
EEECCCCC
>Mature Secondary Structure
MNIIEPGIRNLALAKDILLTPYGLDETLLTRTLADIFTHRVDYADLYFQATRSEAWSLEE
CCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCHHHHEEEECCCHHHCHHH
GIVKSGSFSIDQGVGVRAVAGERTAFAYSDDLSPEAIRQAASATKAIAAAGGGRRRIQVA
HHHCCCCCCCCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
SSLTGVAGRDLYLPSDPLASLDATAKVKLLERVEQMARGRDPRITQVMAGLAGEYDVVLV
HHCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCEEEEE
ARSDGALAADIRPLVRVSVTVIAEQDGRREIGSGGGGGRFDYGYFSDEVLSRYVDDAVHA
ECCCCCEECCCCCEEEEEEEEEECCCCCHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
ALVNLDARPAPAGAMTVVLGSGWPGVLLHEAIGHGLEGDFNRKGSSAFAGRIGERVAAKG
HHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCC
VTVVDDGTLPNRRGSLNIDDEGNPTQCTTLIEDGILKGYIQDTLNARLMKMPVTGNARRE
CEEEECCCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
SYAALPMPRMTNTYMLNGDKDPQEIIASVKHGLYAVNFGGGQVDITNGKFVFSASEAYMI
CEECCCCCCCCCEEEECCCCCHHHHHHHHHCCEEEEEECCCEEEEECCEEEEECCCEEEE
ENGKVTYPVKGATLIGSGPESLKYVSMIGNDMKLDSGVGVCGKEGQSVPVGVGQPTLRID
ECCEEEEEECCCEEECCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEE
SMTVGGTA
EEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]