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The map label for this gene is pntB [H]

Identifier: 238026259

GI number: 238026259

Start: 621766

End: 623220

Strand: Direct

Name: pntB [H]

Synonym: bglu_1g05920

Alternate gene names: 238026259

Gene position: 621766-623220 (Clockwise)

Preceding gene: 238026258

Following gene: 339905957

Centisome position: 15.92

GC content: 67.15

Gene sequence:

>1455_bases
ATGAGCCTGAACCTCGTCACGCTGCTGTACCTGGTCGCCTCGGTCTGCTTTATCCAGGCGCTGAAGGGCCTGTCGAATCC
GAAGAGCGCGCGCCGCGGCAACCTGTTCGGCATGGTCGGCATGGCGATCGCGATGCTCACCACGGTCGCGCTGATCGCGA
AGCAGGCCGCCTGGCTCGGCGCGAACCTGCCGCTCGGGCTCGCGCTGGTGCTCGGCGCGCTGGTGGTGGGCGGCGCGGTG
GGCGCCTATGTGGCCGCGCGCGTCGAAATGACGAAGATGCCCGAGCTGGTGGCCGCGATGCACTCGCTGATCGGCCTCGC
GGCGGTCTCGATCGCCTACGCGGTGGTGGCCGAGCCGGAGGCGTTCGGGCTGGTGCCGCAGGATGCCGTCGCGGCGAACT
TCATCCCCTACGGCAACCGCATCGAGCTGTTCATCGGCACCTTCGTCGGCGCGATCACGTTCTCGGGCTCGGTGATCGCG
TTCGGCAAGCTGTCCGGCAAGTACCGGTTCCGGCTGTTCCAGGGCGCGCCGGTGGTCTATCCGGGCCAGCACCTGATCAA
CCTGATGCTCGCGCTCGGCATGCTCGGCTTCGGCGTGCTGTTCTTCCTCACCCAGTCGTGGCTGCCGTTCATCATCATGA
CGGCGATCGCCTTCGCGCTCGGCGTGCTGATCATCATCCCGATCGGCGGCGCGGACATGCCGGTGGTGGTGTCGATGCTC
AATTCCTACTCGGGATGGGCCGCGGCCGGGATCGGCTTCTCGCTGAACAACCCGATGCTGATCATCGCCGGCTCGCTGGT
GGGCTCGTCGGGGGCGATCCTCTCGTACATCATGTGCCATGCGATGAACCGCTCGTTCTTCAACGTGATCCTGGGCGGCT
TCGGCGGCGAGGCGGCAGCAGCCGGCGCGGGGGCCGCGAAGGAGCAGCGGCCGGTGAAGTCGGGCTCGGCCGACGACGCG
GCGTTCATGCTCGGCAATGCCGAGACGGTGGTGATCGTGCCGGGCTACGGCCTGGCCGTGGCGCGCGCGCAGCATGCGCT
GAAGGAGCTGACCGACAAGCTGGTCGCCAAGGGCATCGACGTGCGCTACGCGATCCATCCGGTGGCCGGGCGCATGCCGG
GGCACATGAACGTGCTGCTGGCCGAGGCCGAGGTGCCGTACGACCTCGTCTACGAGATGGACGACATCAACAACGAGTTC
GGGCAGACCGACGTGGTGCTGGTGCTCGGCGCCAACGACGTGGTGAACCCGGCCGCGAAGAACGATCCGGCCTCGCCGAT
CGCCGGCATGCCGATCCTCGAGGCCTACAAGGCGCGCACCGTGATCGTCAACAAGCGCTCGATGGCCTCGGGCTACGCCG
GGCTCGACAACGAGCTGTTCTACATGGACAAGACCATGATGGTGTTCGGCGACGCCAAGAAGGTGGTCGAGGACATGGTG
AAGGCGGTCGAATAG

Upstream 100 bases:

>100_bases
TCAACGTGTTCGGCGGCTTCCTCGTCACGCGGCGCATGCTGGAGATGTTCCGCAAGAAGGAGCCCAAGCGCGGCGGCGCG
GCGGGCAAGGAGGGCGCGCA

Downstream 100 bases:

>100_bases
CGCCGCGCGCGCCGCTCAGTGGCTGCCGCGCTCCACGGTGCGCAGGAAATCGGCGAGCCGGCGCCCCGCGACGTCGGGAT
AGACCTCGCAGGCCACGATG

Product: NAD(P) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 484; Mature: 483

Protein sequence:

>484_residues
MSLNLVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAMLTTVALIAKQAAWLGANLPLGLALVLGALVVGGAV
GAYVAARVEMTKMPELVAAMHSLIGLAAVSIAYAVVAEPEAFGLVPQDAVAANFIPYGNRIELFIGTFVGAITFSGSVIA
FGKLSGKYRFRLFQGAPVVYPGQHLINLMLALGMLGFGVLFFLTQSWLPFIIMTAIAFALGVLIIIPIGGADMPVVVSML
NSYSGWAAAGIGFSLNNPMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAAAGAGAAKEQRPVKSGSADDA
AFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVAKGIDVRYAIHPVAGRMPGHMNVLLAEAEVPYDLVYEMDDINNEF
GQTDVVLVLGANDVVNPAAKNDPASPIAGMPILEAYKARTVIVNKRSMASGYAGLDNELFYMDKTMMVFGDAKKVVEDMV
KAVE

Sequences:

>Translated_484_residues
MSLNLVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAMLTTVALIAKQAAWLGANLPLGLALVLGALVVGGAV
GAYVAARVEMTKMPELVAAMHSLIGLAAVSIAYAVVAEPEAFGLVPQDAVAANFIPYGNRIELFIGTFVGAITFSGSVIA
FGKLSGKYRFRLFQGAPVVYPGQHLINLMLALGMLGFGVLFFLTQSWLPFIIMTAIAFALGVLIIIPIGGADMPVVVSML
NSYSGWAAAGIGFSLNNPMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAAAGAGAAKEQRPVKSGSADDA
AFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVAKGIDVRYAIHPVAGRMPGHMNVLLAEAEVPYDLVYEMDDINNEF
GQTDVVLVLGANDVVNPAAKNDPASPIAGMPILEAYKARTVIVNKRSMASGYAGLDNELFYMDKTMMVFGDAKKVVEDMV
KAVE
>Mature_483_residues
SLNLVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAMLTTVALIAKQAAWLGANLPLGLALVLGALVVGGAVG
AYVAARVEMTKMPELVAAMHSLIGLAAVSIAYAVVAEPEAFGLVPQDAVAANFIPYGNRIELFIGTFVGAITFSGSVIAF
GKLSGKYRFRLFQGAPVVYPGQHLINLMLALGMLGFGVLFFLTQSWLPFIIMTAIAFALGVLIIIPIGGADMPVVVSMLN
SYSGWAAAGIGFSLNNPMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAAAGAGAAKEQRPVKSGSADDAA
FMLGNAETVVIVPGYGLAVARAQHALKELTDKLVAKGIDVRYAIHPVAGRMPGHMNVLLAEAEVPYDLVYEMDDINNEFG
QTDVVLVLGANDVVNPAAKNDPASPIAGMPILEAYKARTVIVNKRSMASGYAGLDNELFYMDKTMMVFGDAKKVVEDMVK
AVE

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=493, Percent_Identity=45.841784989858, Blast_Score=398, Evalue=1e-111,
Organism=Homo sapiens, GI122939153, Length=493, Percent_Identity=45.841784989858, Blast_Score=398, Evalue=1e-111,
Organism=Escherichia coli, GI1787886, Length=489, Percent_Identity=51.3292433537832, Blast_Score=463, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI17550456, Length=485, Percent_Identity=42.8865979381443, Blast_Score=363, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 50674; Mature: 50543

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNLVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAMLTTVALIAKQAAWLG
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ANLPLGLALVLGALVVGGAVGAYVAARVEMTKMPELVAAMHSLIGLAAVSIAYAVVAEPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCH
AFGLVPQDAVAANFIPYGNRIELFIGTFVGAITFSGSVIAFGKLSGKYRFRLFQGAPVVY
HCCCCCCHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEE
PGQHLINLMLALGMLGFGVLFFLTQSWLPFIIMTAIAFALGVLIIIPIGGADMPVVVSML
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
NSYSGWAAAGIGFSLNNPMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAA
HCCCCCEEECCCEECCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCHHH
AGAGAAKEQRPVKSGSADDAAFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVAKGID
CCCCCCHHCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
VRYAIHPVAGRMPGHMNVLLAEAEVPYDLVYEMDDINNEFGQTDVVLVLGANDVVNPAAK
EEEEEECCCCCCCCCCEEEEEECCCCHHHEEEHHHCCCCCCCCCEEEEECCCCCCCCCCC
NDPASPIAGMPILEAYKARTVIVNKRSMASGYAGLDNELFYMDKTMMVFGDAKKVVEDMV
CCCCCCCCCCHHHHHHCCEEEEEECHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHH
KAVE
HHCC
>Mature Secondary Structure 
SLNLVTLLYLVASVCFIQALKGLSNPKSARRGNLFGMVGMAIAMLTTVALIAKQAAWLG
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHC
ANLPLGLALVLGALVVGGAVGAYVAARVEMTKMPELVAAMHSLIGLAAVSIAYAVVAEPE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCH
AFGLVPQDAVAANFIPYGNRIELFIGTFVGAITFSGSVIAFGKLSGKYRFRLFQGAPVVY
HCCCCCCHHHHHCCCCCCCEEEEHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCEEE
PGQHLINLMLALGMLGFGVLFFLTQSWLPFIIMTAIAFALGVLIIIPIGGADMPVVVSML
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHH
NSYSGWAAAGIGFSLNNPMLIIAGSLVGSSGAILSYIMCHAMNRSFFNVILGGFGGEAAA
HCCCCCEEECCCEECCCCEEEEEECCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCHHH
AGAGAAKEQRPVKSGSADDAAFMLGNAETVVIVPGYGLAVARAQHALKELTDKLVAKGID
CCCCCCHHCCCCCCCCCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
VRYAIHPVAGRMPGHMNVLLAEAEVPYDLVYEMDDINNEFGQTDVVLVLGANDVVNPAAK
EEEEEECCCCCCCCCCEEEEEECCCCHHHEEEHHHCCCCCCCCCEEEEECCCCCCCCCCC
NDPASPIAGMPILEAYKARTVIVNKRSMASGYAGLDNELFYMDKTMMVFGDAKKVVEDMV
CCCCCCCCCCHHHHHHCCEEEEEECHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHH
KAVE
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]