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The map label for this gene is glk [H]

Identifier: 238026220

GI number: 238026220

Start: 580762

End: 581658

Strand: Reverse

Name: glk [H]

Synonym: bglu_1g05510

Alternate gene names: 238026220

Gene position: 581658-580762 (Counterclockwise)

Preceding gene: 238026225

Following gene: 238026210

Centisome position: 14.89

GC content: 71.24

Gene sequence:

>897_bases
ATGCTGCCCCGAATCGAAGCGCTGCGCGCGCAGCTACGCCCTTCCGAGCGCAAGCTCGCCGACTACATGCTGGCCGCGCC
GCGCGAGATCCTCGACCTGTCGATGACCGAGCTCGCCGCGCGCGCGGGCGTGAGCCAGCCCACCATCGCGCGGTTCTGCC
ATGCGCTCGGCTGCAGCGGCTTTCGCGAGTTCAAGATCCGGCTCGCGCAGAGCGTGGCGCCGGGCGTGCCGTCGGTCTAT
CGCGACGTGGAACCCGACGAGCCCGCGCCCGGCATCATCGGCAAGGTGTTCGACCGCACCATCGGCGCGCTGATCGAGGT
GCGCAACAGCCTGTCGGCCGGCAGCGTGGCGGAGGCCATCGCGCTGCTCGCGCGCGCCTCGCGCATCGAGTTCTACGGCG
CGGGCGGCTCCGGCATCGCCGCGCAGGACGTCCAGCACAAGTTCTTCCGGCTCGGCATGCCGAGCGTGGCCTATTCCGAC
CCGCACACCTTCAGCATGTCGGCCGCGCTGCTAGGCGCGCAGGACGTGGTGGTGGCGATTTCGAACACGGGGCGCACGCG
CGACATCGTCGAGGCCGCGAAATCGGCGCTCGCCTGCGGCGCGAAAGTGGTGTCGATCACGCACAGCCACTCGCCGCTGG
CGCAGCTGGCCAGCGTCAATCTCGCCTCGAACATTGCCGAGGAAACCGACGTGTTCTCGCCGATGACCTCGCGCATGTCG
CATCTGGCGATCGGCGACATCCTCGCGGTGGGCGTCGCGCTGCAGCGCGGGCCGGCGCTCGTGGACCGGCTCGGCCGCGC
GAAGGCGGCCATCACGCGGCGCCGCATCGAGCCCGACGGCAAGCCGGCCGAGCGCCGGGGCGCGCGCGACGGGAAGGAAA
CCGAAACGCAGGCCTGA

Upstream 100 bases:

>100_bases
GTCGTGCCACGACGTCGACACTTCAGCTAGAAATTTCCTGTAGTTTTTCTACAATACCGCCACACGCCTACAATCCGTCA
TTTGCGAAAACGAGCCGCCG

Downstream 100 bases:

>100_bases
GCGGCCCGCGCCGCCTGAGGACGCCGCCGGGCGGCGGCGATGATGCCGCCCAGCGACGATGGCGCGGCCGCTATCGCCGA
GCGCGCGCGGCGGCGCGAAG

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: Glucokinase; Glucose kinase; Putative HTH-type transcriptional regulator [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MLPRIEALRAQLRPSERKLADYMLAAPREILDLSMTELAARAGVSQPTIARFCHALGCSGFREFKIRLAQSVAPGVPSVY
RDVEPDEPAPGIIGKVFDRTIGALIEVRNSLSAGSVAEAIALLARASRIEFYGAGGSGIAAQDVQHKFFRLGMPSVAYSD
PHTFSMSAALLGAQDVVVAISNTGRTRDIVEAAKSALACGAKVVSITHSHSPLAQLASVNLASNIAEETDVFSPMTSRMS
HLAIGDILAVGVALQRGPALVDRLGRAKAAITRRRIEPDGKPAERRGARDGKETETQA

Sequences:

>Translated_298_residues
MLPRIEALRAQLRPSERKLADYMLAAPREILDLSMTELAARAGVSQPTIARFCHALGCSGFREFKIRLAQSVAPGVPSVY
RDVEPDEPAPGIIGKVFDRTIGALIEVRNSLSAGSVAEAIALLARASRIEFYGAGGSGIAAQDVQHKFFRLGMPSVAYSD
PHTFSMSAALLGAQDVVVAISNTGRTRDIVEAAKSALACGAKVVSITHSHSPLAQLASVNLASNIAEETDVFSPMTSRMS
HLAIGDILAVGVALQRGPALVDRLGRAKAAITRRRIEPDGKPAERRGARDGKETETQA
>Mature_298_residues
MLPRIEALRAQLRPSERKLADYMLAAPREILDLSMTELAARAGVSQPTIARFCHALGCSGFREFKIRLAQSVAPGVPSVY
RDVEPDEPAPGIIGKVFDRTIGALIEVRNSLSAGSVAEAIALLARASRIEFYGAGGSGIAAQDVQHKFFRLGMPSVAYSD
PHTFSMSAALLGAQDVVVAISNTGRTRDIVEAAKSALACGAKVVSITHSHSPLAQLASVNLASNIAEETDVFSPMTSRMS
HLAIGDILAVGVALQRGPALVDRLGRAKAAITRRRIEPDGKPAERRGARDGKETETQA

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=278, Percent_Identity=39.2086330935252, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87082369, Length=271, Percent_Identity=29.520295202952, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082130, Length=233, Percent_Identity=33.4763948497854, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788767, Length=281, Percent_Identity=26.3345195729537, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836
- InterPro:   IPR000843
- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02685 Glucokinase; PF01418 HTH_6; PF01380 SIS [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 31604; Mature: 31604

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00356 HTH_LACI_1 ; PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPRIEALRAQLRPSERKLADYMLAAPREILDLSMTELAARAGVSQPTIARFCHALGCSG
CCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
FREFKIRLAQSVAPGVPSVYRDVEPDEPAPGIIGKVFDRTIGALIEVRNSLSAGSVAEAI
HHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALLARASRIEFYGAGGSGIAAQDVQHKFFRLGMPSVAYSDPHTFSMSAALLGAQDVVVAI
HHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEE
SNTGRTRDIVEAAKSALACGAKVVSITHSHSPLAQLASVNLASNIAEETDVFSPMTSRMS
CCCCCHHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLAIGDILAVGVALQRGPALVDRLGRAKAAITRRRIEPDGKPAERRGARDGKETETQA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLPRIEALRAQLRPSERKLADYMLAAPREILDLSMTELAARAGVSQPTIARFCHALGCSG
CCCHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCC
FREFKIRLAQSVAPGVPSVYRDVEPDEPAPGIIGKVFDRTIGALIEVRNSLSAGSVAEAI
HHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
ALLARASRIEFYGAGGSGIAAQDVQHKFFRLGMPSVAYSDPHTFSMSAALLGAQDVVVAI
HHHHHHHHEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEEEE
SNTGRTRDIVEAAKSALACGAKVVSITHSHSPLAQLASVNLASNIAEETDVFSPMTSRMS
CCCCCHHHHHHHHHHHHHCCHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HLAIGDILAVGVALQRGPALVDRLGRAKAAITRRRIEPDGKPAERRGARDGKETETQA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA