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The map label for this gene is rocA [H]

Identifier: 238026119

GI number: 238026119

Start: 466127

End: 467821

Strand: Reverse

Name: rocA [H]

Synonym: bglu_1g04490

Alternate gene names: 238026119

Gene position: 467821-466127 (Counterclockwise)

Preceding gene: 238026140

Following gene: 238026118

Centisome position: 11.98

GC content: 70.15

Gene sequence:

>1695_bases
ATGACCCATCCCCTCTTCACGAAGCACGAAGCCACTTTGCAGCGGGCCTTGTCCGCCATTGAAACCCGTGGTTACTGGAG
TCCGTTCGCGGAAATGCCTAGCCCCAAAGTGTACGGGGAAAGCGCGGCGGCGGATGGCGAGGCCGCCTTCAAGGCCCAGC
TCGGCCAACGCTTCGCGCTCGACCAGCCGGGCACGGGCGGCGAGGTAGGCGCCGAGCTGTCGCCGTATGGTTTTGCGCTC
GGCATTCGTTATCCGGCGGCGACGCCGGACCAGCTCGCGGCAGCGGCGGCGGCGGCCCAGCCGGCCTGGCGCGCGGCCGG
CCCGAGCGCCTGGATCGGCGTGAGCCTGGAAATCCTGGCTCGCCTCAACCGCGCCAGCTTCGAACTGGCCAACGCCGTGA
TGCATACCACCGGCCAAGCCTTCATGATGGCGTTCCAGGCCGGCGGCCCGCACGCGCAGGACCGCGCGCTGGAAGCGGTG
GCCTACGCCTGGGACGCGCTGCGCAAGATCCCGGCCGACGCCCACTGGGAAAAGCCGCAAGGCAAGAACCCGCCGCTCGC
GATGCAGAAGCGCTACACGATCGTGCCGCGCGGCACCGGCCTCGTGCTCGGCTGCTGCACGTTCCCGACCTGGAACGGCT
ACCCGGGCCTGTTCGCCGATCTCGCGACCGGCAATACGGTGATCGTCAAGCCGCATCCGGGCGCGATCCTGCCGCTCGCG
ATCACGGTGCGCATCGCGCGCGAGGTGCTGCGCGAGGCCGGCTTCGATCCGAACGTCGTCACGCTGCTGGCGACCGACCC
CGACGACGGCGCACTCGTGCAGGCGCTCGCGGTGCGCCCCGACATCAAGCTGATCGACTTCACGGGCAGCAGCGAGCACG
GCAACTGGCTCGAGCGTCACGCGCGCCAGGCGCAGGTGTATACGGAGAAGGCCGGCGTCAACCAGATCGTCATCGACTCG
GCCGACGACCTGAAGGGCGCGGTGCGCAACATCGCGTTCTCGCTGGCGCTGTATGCCGGCCAGATGTGTACCGCGCCGCA
GAACATCTATGTGCCGCGCGACGGCATCGAGACGCCGGACGGCAAGCTGAGCTTTGACGAGATCGCGCAGGCGATCGCCG
GCGCCGTAAGCAAGCTCGGTGCCGATCCCGCGCGCGCCGTCGAGCTGCTCGGCGCGATCCAGAACGACGGCGTGATCGCG
CGCATCGACGAGGCGCGCGGGCTCGGCAAGGTGCTGGCCGATAGCGTCGCGCTCGAACACCCGGCCCATCCGCGGGCCCG
CATCCGTACGCCGCTCGTCGTGCAGCTCGACGCGGGCGACCGAGGCATCTTCACGCGCGAGTGGTTCGGCCCGATCTCGT
TCGTGATCGCGACCGACTCGACCGCGCAGTCGCTCGACCTGGCAGGCGGCATTGCGGCCGAATGCGGCGCGCTGACCCTG
TCGGTCTACAGCACCGACGCGGCGGTGATCGAGCAGGCGCACGACGCGGCGATCCGCGGCGGCGTCGCGCTGTCGATCAA
CCTGACGGGCGGCGTATTCGTAAACCAGTCGGCCGCCTTCTCCGACTTCCACGCCACCGGCGCGAACCCGGCCGCGAACG
CCGCGCTCGCCGACGCGGCGTTCGTCGCAAACCGCTTCCGCGTCGTGCAAAGCCGCATCCACGTCGCGCCGCAGGCCGAC
ACCGCCGGCGCCTGA

Upstream 100 bases:

>100_bases
GCACACGCGCCGGGAAGGATGCTAACATTTGCCGACCAACCGGTCGGTTAATTAATTACGTCCGCACGAACGCCCTCGTC
CCCTCAACCAGGCTGCCGTC

Downstream 100 bases:

>100_bases
GCCATCCCCGCCGCACCGGCCGGCACGGCGCCGGCCGCGCGTCTCCATGAGGAGATCCCGATGTCGCACGATACGATCCG
CTTCGAGCTCGACCCGCAGA

Product: phenylacetic acid degradation protein paaN

Products: NA

Alternate protein names: P5C dehydrogenase [H]

Number of amino acids: Translated: 564; Mature: 563

Protein sequence:

>564_residues
MTHPLFTKHEATLQRALSAIETRGYWSPFAEMPSPKVYGESAAADGEAAFKAQLGQRFALDQPGTGGEVGAELSPYGFAL
GIRYPAATPDQLAAAAAAAQPAWRAAGPSAWIGVSLEILARLNRASFELANAVMHTTGQAFMMAFQAGGPHAQDRALEAV
AYAWDALRKIPADAHWEKPQGKNPPLAMQKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
ITVRIAREVLREAGFDPNVVTLLATDPDDGALVQALAVRPDIKLIDFTGSSEHGNWLERHARQAQVYTEKAGVNQIVIDS
ADDLKGAVRNIAFSLALYAGQMCTAPQNIYVPRDGIETPDGKLSFDEIAQAIAGAVSKLGADPARAVELLGAIQNDGVIA
RIDEARGLGKVLADSVALEHPAHPRARIRTPLVVQLDAGDRGIFTREWFGPISFVIATDSTAQSLDLAGGIAAECGALTL
SVYSTDAAVIEQAHDAAIRGGVALSINLTGGVFVNQSAAFSDFHATGANPAANAALADAAFVANRFRVVQSRIHVAPQAD
TAGA

Sequences:

>Translated_564_residues
MTHPLFTKHEATLQRALSAIETRGYWSPFAEMPSPKVYGESAAADGEAAFKAQLGQRFALDQPGTGGEVGAELSPYGFAL
GIRYPAATPDQLAAAAAAAQPAWRAAGPSAWIGVSLEILARLNRASFELANAVMHTTGQAFMMAFQAGGPHAQDRALEAV
AYAWDALRKIPADAHWEKPQGKNPPLAMQKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
ITVRIAREVLREAGFDPNVVTLLATDPDDGALVQALAVRPDIKLIDFTGSSEHGNWLERHARQAQVYTEKAGVNQIVIDS
ADDLKGAVRNIAFSLALYAGQMCTAPQNIYVPRDGIETPDGKLSFDEIAQAIAGAVSKLGADPARAVELLGAIQNDGVIA
RIDEARGLGKVLADSVALEHPAHPRARIRTPLVVQLDAGDRGIFTREWFGPISFVIATDSTAQSLDLAGGIAAECGALTL
SVYSTDAAVIEQAHDAAIRGGVALSINLTGGVFVNQSAAFSDFHATGANPAANAALADAAFVANRFRVVQSRIHVAPQAD
TAGA
>Mature_563_residues
THPLFTKHEATLQRALSAIETRGYWSPFAEMPSPKVYGESAAADGEAAFKAQLGQRFALDQPGTGGEVGAELSPYGFALG
IRYPAATPDQLAAAAAAAQPAWRAAGPSAWIGVSLEILARLNRASFELANAVMHTTGQAFMMAFQAGGPHAQDRALEAVA
YAWDALRKIPADAHWEKPQGKNPPLAMQKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLAI
TVRIAREVLREAGFDPNVVTLLATDPDDGALVQALAVRPDIKLIDFTGSSEHGNWLERHARQAQVYTEKAGVNQIVIDSA
DDLKGAVRNIAFSLALYAGQMCTAPQNIYVPRDGIETPDGKLSFDEIAQAIAGAVSKLGADPARAVELLGAIQNDGVIAR
IDEARGLGKVLADSVALEHPAHPRARIRTPLVVQLDAGDRGIFTREWFGPISFVIATDSTAQSLDLAGGIAAECGALTLS
VYSTDAAVIEQAHDAAIRGGVALSINLTGGVFVNQSAAFSDFHATGANPAANAALADAAFVANRFRVVQSRIHVAPQADT
AGA

Specific function: Oxidizes Proline To Glutamate For Use As A Carbon And Nitrogen Source And Also Function As A Transcriptional Repressor Of The Put Operon. [C]

COG id: COG1012

COG function: function code C; NAD-dependent aldehyde dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family. RocA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787250, Length=363, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115534176, Length=300, Percent_Identity=24.3333333333333, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320917, Length=287, Percent_Identity=28.9198606271777, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323822, Length=309, Percent_Identity=27.1844660194175, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24666674, Length=281, Percent_Identity=27.0462633451957, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005932 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.5.1.12 [H]

Molecular weight: Translated: 59266; Mature: 59134

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPLFTKHEATLQRALSAIETRGYWSPFAEMPSPKVYGESAAADGEAAFKAQLGQRFAL
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHCCEECC
DQPGTGGEVGAELSPYGFALGIRYPAATPDQLAAAAAAAQPAWRAAGPSAWIGVSLEILA
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCHHCCCCCCEECHHHHHHH
RLNRASFELANAVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWDALRKIPADAHWEKPQ
HHHHHHHHHHHHHHHCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GKNPPLAMQKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
CCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHECCCCCEEEECCCCCCEEHHH
ITVRIAREVLREAGFDPNVVTLLATDPDDGALVQALAVRPDIKLIDFTGSSEHGNWLERH
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHEEECCCCEEEEECCCCCCCHHHHHH
ARQAQVYTEKAGVNQIVIDSADDLKGAVRNIAFSLALYAGQMCTAPQNIYVPRDGIETPD
HHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCHHCCCCCCEEECCCCCCCCC
GKLSFDEIAQAIAGAVSKLGADPARAVELLGAIQNDGVIARIDEARGLGKVLADSVALEH
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHHCC
PAHPRARIRTPLVVQLDAGDRGIFTREWFGPISFVIATDSTAQSLDLAGGIAAECGALTL
CCCCHHHCCCCEEEEECCCCCCCEEHHCCCCEEEEEECCCCHHHHHHCCCCHHCCCEEEE
SVYSTDAAVIEQAHDAAIRGGVALSINLTGGVFVNQSAAFSDFHATGANPAANAALADAA
EEECCCHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHH
FVANRFRVVQSRIHVAPQADTAGA
HHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
THPLFTKHEATLQRALSAIETRGYWSPFAEMPSPKVYGESAAADGEAAFKAQLGQRFAL
CCCCCCCHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHCCEECC
DQPGTGGEVGAELSPYGFALGIRYPAATPDQLAAAAAAAQPAWRAAGPSAWIGVSLEILA
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCHHCCCCCCEECHHHHHHH
RLNRASFELANAVMHTTGQAFMMAFQAGGPHAQDRALEAVAYAWDALRKIPADAHWEKPQ
HHHHHHHHHHHHHHHCCCHHEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GKNPPLAMQKRYTIVPRGTGLVLGCCTFPTWNGYPGLFADLATGNTVIVKPHPGAILPLA
CCCCCCCCCCCEEEEECCCCEEEEEECCCCCCCCCCHHHECCCCCEEEECCCCCCEEHHH
ITVRIAREVLREAGFDPNVVTLLATDPDDGALVQALAVRPDIKLIDFTGSSEHGNWLERH
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHEEECCCCEEEEECCCCCCCHHHHHH
ARQAQVYTEKAGVNQIVIDSADDLKGAVRNIAFSLALYAGQMCTAPQNIYVPRDGIETPD
HHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHCHHCCCCCCEEECCCCCCCCC
GKLSFDEIAQAIAGAVSKLGADPARAVELLGAIQNDGVIARIDEARGLGKVLADSVALEH
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEHHHCCHHHHHHHHHHHCC
PAHPRARIRTPLVVQLDAGDRGIFTREWFGPISFVIATDSTAQSLDLAGGIAAECGALTL
CCCCHHHCCCCEEEEECCCCCCCEEHHCCCCEEEEEECCCCHHHHHHCCCCHHCCCEEEE
SVYSTDAAVIEQAHDAAIRGGVALSINLTGGVFVNQSAAFSDFHATGANPAANAALADAA
EEECCCHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCCCCCCCHHHHHHHHHH
FVANRFRVVQSRIHVAPQADTAGA
HHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA