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The map label for this gene is gph [C]

Identifier: 238026112

GI number: 238026112

Start: 460130

End: 460843

Strand: Reverse

Name: gph [C]

Synonym: bglu_1g04410

Alternate gene names: 238026112

Gene position: 460843-460130 (Counterclockwise)

Preceding gene: 238026113

Following gene: 238026111

Centisome position: 11.8

GC content: 68.77

Gene sequence:

>714_bases
ATGACGACGATCCGCTTCGCCGCGCCGAGGCTCGCGGCCGCGCTAATCGATCTGGACGGCACCATGATCGACACCGCCGA
CGATTTCACGGCGGGCCTGAACGCCATGCTCGCCCGGCTGGGCGCCCCGGCCACGACGCGCGACGAGGTCATGCATTACG
TCGGCAAGGGCTCCGAGAACCTGATCGCGCAGGTGCTGAAGCCGCGCTTTGCCGAGGCCGAGGCGCAGGCTCGCTTCGAC
GACGCGCTGGCGATCTACCAGACCGAATACGCCAAGATCAACGGCCGTCACACGCGGCTCTACCCCGACGTCGAGGGCGG
CCTGCGCGCGATGCGCGAGGCGGGCCTCGCGCTCGCCTGCGTGACCAACAAGCCGCTGCGCTTCGCCGCCGAGCTGCTCG
CGCAATACGCGCTGGACGGCTATTTCGGCGTGGTGCTCGGCGGCGACAGCCTGCCGCGCAAGAAGCCCGACCCGCTGCCG
ATGCTCGCCGCCTGCGAGCGGCTCGGTGTCGAACCGGCGCTGGCGGTGGCCATCGGCGACTCGGAAAACGACGCGATCGC
GGGCCGCGCGGCGGGCCTCGCGACGCTGACGGTGCCCTACGGCTACAACCATGGCAAGGCTATACAAACGATAAATTCGG
ATGGTATAGTCGGCTCGCTGCTCGTGGCGGCGCAGGTCATCACCGCGCACAATCGCATCGGGCATACCCTCTGA

Upstream 100 bases:

>100_bases
ACCTTCGTGGCCGGCTCCGCGATCTTCGGCAAGCCCGACTACCGGGCCGTGATCGACGAGATGCGCGCGTCGCTCGCCGG
CGTTGCGAAGGGCTGAGCCG

Downstream 100 bases:

>100_bases
TTTGATCTTCCACCGCATGTTTCTGAACAAAAAACGGAGTCTGAGCAGCATCGACCGGGGAGCCTGGCCCTGGCGTCGCT
GGTCGCGCTAACCTCGTCGA

Product: putative phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTTIRFAAPRLAAALIDLDGTMIDTADDFTAGLNAMLARLGAPATTRDEVMHYVGKGSENLIAQVLKPRFAEAEAQARFD
DALAIYQTEYAKINGRHTRLYPDVEGGLRAMREAGLALACVTNKPLRFAAELLAQYALDGYFGVVLGGDSLPRKKPDPLP
MLAACERLGVEPALAVAIGDSENDAIAGRAAGLATLTVPYGYNHGKAIQTINSDGIVGSLLVAAQVITAHNRIGHTL

Sequences:

>Translated_237_residues
MTTIRFAAPRLAAALIDLDGTMIDTADDFTAGLNAMLARLGAPATTRDEVMHYVGKGSENLIAQVLKPRFAEAEAQARFD
DALAIYQTEYAKINGRHTRLYPDVEGGLRAMREAGLALACVTNKPLRFAAELLAQYALDGYFGVVLGGDSLPRKKPDPLP
MLAACERLGVEPALAVAIGDSENDAIAGRAAGLATLTVPYGYNHGKAIQTINSDGIVGSLLVAAQVITAHNRIGHTL
>Mature_236_residues
TTIRFAAPRLAAALIDLDGTMIDTADDFTAGLNAMLARLGAPATTRDEVMHYVGKGSENLIAQVLKPRFAEAEAQARFDD
ALAIYQTEYAKINGRHTRLYPDVEGGLRAMREAGLALACVTNKPLRFAAELLAQYALDGYFGVVLGGDSLPRKKPDPLPM
LAACERLGVEPALAVAIGDSENDAIAGRAAGLATLTVPYGYNHGKAIQTINSDGIVGSLLVAAQVITAHNRIGHTL

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=223, Percent_Identity=34.5291479820628, Blast_Score=124, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 25072; Mature: 24941

Theoretical pI: Translated: 6.02; Mature: 6.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIRFAAPRLAAALIDLDGTMIDTADDFTAGLNAMLARLGAPATTRDEVMHYVGKGSEN
CCEEECCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHH
LIAQVLKPRFAEAEAQARFDDALAIYQTEYAKINGRHTRLYPDVEGGLRAMREAGLALAC
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCHHHHHHHHHHCCEEEEE
VTNKPLRFAAELLAQYALDGYFGVVLGGDSLPRKKPDPLPMLAACERLGVEPALAVAIGD
ECCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
SENDAIAGRAAGLATLTVPYGYNHGKAIQTINSDGIVGSLLVAAQVITAHNRIGHTL
CCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TTIRFAAPRLAAALIDLDGTMIDTADDFTAGLNAMLARLGAPATTRDEVMHYVGKGSEN
CEEECCHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHH
LIAQVLKPRFAEAEAQARFDDALAIYQTEYAKINGRHTRLYPDVEGGLRAMREAGLALAC
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEECCCHHHHHHHHHHCCEEEEE
VTNKPLRFAAELLAQYALDGYFGVVLGGDSLPRKKPDPLPMLAACERLGVEPALAVAIGD
ECCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEECC
SENDAIAGRAAGLATLTVPYGYNHGKAIQTINSDGIVGSLLVAAQVITAHNRIGHTL
CCCCCCCCCCCCEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA