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The map label for this gene is trpC [H]

Identifier: 238026107

GI number: 238026107

Start: 453881

End: 454672

Strand: Reverse

Name: trpC [H]

Synonym: bglu_1g04360

Alternate gene names: 238026107

Gene position: 454672-453881 (Counterclockwise)

Preceding gene: 238026108

Following gene: 238026106

Centisome position: 11.64

GC content: 69.07

Gene sequence:

>792_bases
ATGAGCGACATCCTCAATCGAATCATTGCCGTCAAACGCGAAGAAATCGCCGCCGGGCTGCGCAGCACGCCGCTCGAGGC
GCTGCGGCTCGAAGCCGAGGCGCGCGGCGCCGACACGCGCGACTTCGTCGGCGCGCTGCGCGCGCAGCACGCGGCCGGCC
GCAGCGCCGTGATCGCCGAAGTGAAGAAGGCGAGCCCCTCGAAAGGCGTGCTGCGCGAGCACTTCGTGCCGGCCGAAATC
GCCGCCTCCTACGCACGGCACGGCGCGGCCTGCCTGTCGGTGCTGACCGACGAACAGTTCTTCCAGGGCGGCGCGCGCTA
CCTACGCGAGGCGCGCGAGGCCTGCGCGCTGCCGGTGCTGCGCAAGGACTTCATCATCGACCCGTACCAGGTGCTCGAGG
CGCGCGCGATGGGCGCCGACGCGATCCTGCTGATCGCCGCGGCGCTCGACACGCCGCAGATGCAGGACCTCGAAGCCTAT
GCGCACTCGCTCGGCCTCGCGGTGCTGGTCGAAGTCCACGATCGCGACGAGATGGCCAATGCGCTGACGCTGAAGACGCC
GCTGATCGGCATCAACAACCGCAATCTGCGCAGCTTCGAGACCACGCTCGACACCACGCTCGGCATGCTCGAGATGGTGC
CGGCCGAGCGCATCGTCGTGACCGAATCGGGCATCCGCACGCGCGACGACGTCGAGCGCATGAGGCGCGCGGGCGTCCAT
ACGTTCCTCGTCGGCGAGGCGTTCATGCGCGCCGAGCAGCCGGGCGAAGAACTCGCGCGGATGTTCTTCTGA

Upstream 100 bases:

>100_bases
GTACGCTTCACCTGTCAATTCGGGCGCTGAGCGCCCGCCCGCCGGCCGGCACCGCCGGCTCCCCCAACCCATCATGCGGA
CCGCGCTCCGCCGGAATGCC

Downstream 100 bases:

>100_bases
GCCTGCCGAGGCCGCCCATGGCGATCGAAACCGAAATCAAGCTCGCGCTGCCGGCCGGCGCGCACACCGCGGCGCGCCTC
GCGCTCGACGCCTGCGCCGG

Product: indole-3-glycerol-phosphate synthase

Products: NA

Alternate protein names: IGPS [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSDILNRIIAVKREEIAAGLRSTPLEALRLEAEARGADTRDFVGALRAQHAAGRSAVIAEVKKASPSKGVLREHFVPAEI
AASYARHGAACLSVLTDEQFFQGGARYLREAREACALPVLRKDFIIDPYQVLEARAMGADAILLIAAALDTPQMQDLEAY
AHSLGLAVLVEVHDRDEMANALTLKTPLIGINNRNLRSFETTLDTTLGMLEMVPAERIVVTESGIRTRDDVERMRRAGVH
TFLVGEAFMRAEQPGEELARMFF

Sequences:

>Translated_263_residues
MSDILNRIIAVKREEIAAGLRSTPLEALRLEAEARGADTRDFVGALRAQHAAGRSAVIAEVKKASPSKGVLREHFVPAEI
AASYARHGAACLSVLTDEQFFQGGARYLREAREACALPVLRKDFIIDPYQVLEARAMGADAILLIAAALDTPQMQDLEAY
AHSLGLAVLVEVHDRDEMANALTLKTPLIGINNRNLRSFETTLDTTLGMLEMVPAERIVVTESGIRTRDDVERMRRAGVH
TFLVGEAFMRAEQPGEELARMFF
>Mature_262_residues
SDILNRIIAVKREEIAAGLRSTPLEALRLEAEARGADTRDFVGALRAQHAAGRSAVIAEVKKASPSKGVLREHFVPAEIA
ASYARHGAACLSVLTDEQFFQGGARYLREAREACALPVLRKDFIIDPYQVLEARAMGADAILLIAAALDTPQMQDLEAYA
HSLGLAVLVEVHDRDEMANALTLKTPLIGINNRNLRSFETTLDTTLGMLEMVPAERIVVTESGIRTRDDVERMRRAGVHT
FLVGEAFMRAEQPGEELARMFF

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0134

COG function: function code E; Indole-3-glycerol phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpC family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=249, Percent_Identity=40.9638554216867, Blast_Score=167, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6322638, Length=220, Percent_Identity=42.2727272727273, Blast_Score=176, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013798
- InterPro:   IPR001468
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00218 IGPS [H]

EC number: =4.1.1.48 [H]

Molecular weight: Translated: 28897; Mature: 28765

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00614 IGPS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDILNRIIAVKREEIAAGLRSTPLEALRLEAEARGADTRDFVGALRAQHAAGRSAVIAE
CHHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHH
VKKASPSKGVLREHFVPAEIAASYARHGAACLSVLTDEQFFQGGARYLREAREACALPVL
HHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
RKDFIIDPYQVLEARAMGADAILLIAAALDTPQMQDLEAYAHSLGLAVLVEVHDRDEMAN
HHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHH
ALTLKTPLIGINNRNLRSFETTLDTTLGMLEMVPAERIVVTESGIRTRDDVERMRRAGVH
EEEEECCEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCH
TFLVGEAFMRAEQPGEELARMFF
HHHHHHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure 
SDILNRIIAVKREEIAAGLRSTPLEALRLEAEARGADTRDFVGALRAQHAAGRSAVIAE
HHHHHHHHHHHHHHHHHCHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHH
VKKASPSKGVLREHFVPAEIAASYARHGAACLSVLTDEQFFQGGARYLREAREACALPVL
HHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
RKDFIIDPYQVLEARAMGADAILLIAAALDTPQMQDLEAYAHSLGLAVLVEVHDRDEMAN
HHHHCCCHHHHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEEEECCHHHHHH
ALTLKTPLIGINNRNLRSFETTLDTTLGMLEMVPAERIVVTESGIRTRDDVERMRRAGVH
EEEEECCEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHCCCH
TFLVGEAFMRAEQPGEELARMFF
HHHHHHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA