Click here to switch to the map view.

The map label for this gene is trpD [H]

Identifier: 238026108

GI number: 238026108

Start: 454743

End: 455771

Strand: Reverse

Name: trpD [H]

Synonym: bglu_1g04370

Alternate gene names: 238026108

Gene position: 455771-454743 (Counterclockwise)

Preceding gene: 238026109

Following gene: 238026107

Centisome position: 11.67

GC content: 67.15

Gene sequence:

>1029_bases
ATGATCACTGCGCAGGAAGCGCTGCAACGCACGATCGAGCACCGCGAAATCTTCCACGACGAGATGCTGCACCTGATGCG
CATGATCATGCGCGGGGACATGTCGCCCGTGATGGCCGCCGCGATCATCACCGGCCTGCGCGTGAAAAAGGAGACGATCG
GCGAGATCGCCGCGGCGGCCACCGTGATGCGCGAGTTCGCGCGCCATGTCGAGGTCTCCGACAATTCGAACTTCGTCGAT
ATCGTCGGCACCGGCGGCGACGGCTCGCACACCTTCAATATCTCGACGGCCACCATGTTCGTGACGGCCGCGGCCGGCGC
GAAGGTCGCCAAGCACGGCAACCGCGGCGTGTCGAGCAAGTCGGGCAGCGCGGACGTGCTCGATGCGCTCGGCGTCAACA
TCGATCTCGCGCCCGAGCAGGTGGCGGCCTCGATCGAGGCGACCGGCATGGGCTTCATGTACGCGCCGAACCACCATCCG
GCGATGAAGAACATCGCGCCGGTGCGCCGCGAGCTCGGCGTGCGCACCATCTTCAACATCCTCGGCCCGCTGACCAATCC
GGCCGGCGCGCCGAACCAGCTGATGGGCGTGTTCCACCCCGATCTGGTCGGCATCCAGGTCCGCGTGATGCAACGGCTCG
GCGCCGAGCACGTGCTGGTGGTCTACGGCAAGGACGGCATGGACGAGGTCTCGCTCGGCGCGGCCACGCTGGTGGGCGAG
CTGCGCGACGGCAAGGTCACCGAGTACGAGATCCATCCCGAGGATTTCGGCCTGCAGATGGTGTCGAACCGCTCGCTGAA
GGTGGAGAACGCCGAGGAATCGCGCGCGATGCTGCTCGAGGCGCTCGACAACAAGCCCGGCGTGGCGCGCGAGATCGTCA
CGCTGAACGCCGGCACCGCGCTCTATGCGGCCAACATCGCGCCGTCGATCGCTGCCGGCATCGACACGGCACGCGAGGCG
ATCGCGAGCGGCCGCGCGCGCGCCAAGGTCGACGAACTGGTACGCTTCACCTGTCAATTCGGGCGCTGA

Upstream 100 bases:

>100_bases
ATCCCGAATCGATCCTCTCCGAGCACGGCCACGCCTTGCTCGAGAACTTCCTGAAGCAGGCGCGCGCCGGCAGCGCGCAG
CCGGCATGAGCGAGGGCGCG

Downstream 100 bases:

>100_bases
GCGCCCGCCCGCCGGCCGGCACCGCCGGCTCCCCCAACCCATCATGCGGACCGCGCTCCGCCGGAATGCCATGAGCGACA
TCCTCAATCGAATCATTGCC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MITAQEALQRTIEHREIFHDEMLHLMRMIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARHVEVSDNSNFVD
IVGTGGDGSHTFNISTATMFVTAAAGAKVAKHGNRGVSSKSGSADVLDALGVNIDLAPEQVAASIEATGMGFMYAPNHHP
AMKNIAPVRRELGVRTIFNILGPLTNPAGAPNQLMGVFHPDLVGIQVRVMQRLGAEHVLVVYGKDGMDEVSLGAATLVGE
LRDGKVTEYEIHPEDFGLQMVSNRSLKVENAEESRAMLLEALDNKPGVAREIVTLNAGTALYAANIAPSIAAGIDTAREA
IASGRARAKVDELVRFTCQFGR

Sequences:

>Translated_342_residues
MITAQEALQRTIEHREIFHDEMLHLMRMIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARHVEVSDNSNFVD
IVGTGGDGSHTFNISTATMFVTAAAGAKVAKHGNRGVSSKSGSADVLDALGVNIDLAPEQVAASIEATGMGFMYAPNHHP
AMKNIAPVRRELGVRTIFNILGPLTNPAGAPNQLMGVFHPDLVGIQVRVMQRLGAEHVLVVYGKDGMDEVSLGAATLVGE
LRDGKVTEYEIHPEDFGLQMVSNRSLKVENAEESRAMLLEALDNKPGVAREIVTLNAGTALYAANIAPSIAAGIDTAREA
IASGRARAKVDELVRFTCQFGR
>Mature_342_residues
MITAQEALQRTIEHREIFHDEMLHLMRMIMRGDMSPVMAAAIITGLRVKKETIGEIAAAATVMREFARHVEVSDNSNFVD
IVGTGGDGSHTFNISTATMFVTAAAGAKVAKHGNRGVSSKSGSADVLDALGVNIDLAPEQVAASIEATGMGFMYAPNHHP
AMKNIAPVRRELGVRTIFNILGPLTNPAGAPNQLMGVFHPDLVGIQVRVMQRLGAEHVLVVYGKDGMDEVSLGAATLVGE
LRDGKVTEYEIHPEDFGLQMVSNRSLKVENAEESRAMLLEALDNKPGVAREIVTLNAGTALYAANIAPSIAAGIDTAREA
IASGRARAKVDELVRFTCQFGR

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=331, Percent_Identity=39.5770392749245, Blast_Score=207, Evalue=6e-55,
Organism=Saccharomyces cerevisiae, GI6320561, Length=355, Percent_Identity=27.0422535211268, Blast_Score=115, Evalue=1e-26,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 36565; Mature: 36565

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITAQEALQRTIEHREIFHDEMLHLMRMIMRGDMSPVMAAAIITGLRVKKETIGEIAAAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVMREFARHVEVSDNSNFVDIVGTGGDGSHTFNISTATMFVTAAAGAKVAKHGNRGVSSK
HHHHHHHHHEECCCCCCEEEEEECCCCCCEEEEEEHHHEEEEHHCCCHHHHCCCCCCCCC
SGSADVLDALGVNIDLAPEQVAASIEATGMGFMYAPNHHPAMKNIAPVRRELGVRTIFNI
CCCHHHHHHHCCCEEECHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
LGPLTNPAGAPNQLMGVFHPDLVGIQVRVMQRLGAEHVLVVYGKDGMDEVSLGAATLVGE
HCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHH
LRDGKVTEYEIHPEDFGLQMVSNRSLKVENAEESRAMLLEALDNKPGVAREIVTLNAGTA
CCCCCEEEEEECCHHCCEEEECCCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCE
LYAANIAPSIAAGIDTAREAIASGRARAKVDELVRFTCQFGR
EEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MITAQEALQRTIEHREIFHDEMLHLMRMIMRGDMSPVMAAAIITGLRVKKETIGEIAAAA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TVMREFARHVEVSDNSNFVDIVGTGGDGSHTFNISTATMFVTAAAGAKVAKHGNRGVSSK
HHHHHHHHHEECCCCCCEEEEEECCCCCCEEEEEEHHHEEEEHHCCCHHHHCCCCCCCCC
SGSADVLDALGVNIDLAPEQVAASIEATGMGFMYAPNHHPAMKNIAPVRRELGVRTIFNI
CCCHHHHHHHCCCEEECHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
LGPLTNPAGAPNQLMGVFHPDLVGIQVRVMQRLGAEHVLVVYGKDGMDEVSLGAATLVGE
HCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHH
LRDGKVTEYEIHPEDFGLQMVSNRSLKVENAEESRAMLLEALDNKPGVAREIVTLNAGTA
CCCCCEEEEEECCHHCCEEEECCCCEEECCCHHHHHHHHHHHCCCCCCEEEEEEECCCCE
LYAANIAPSIAAGIDTAREAIASGRARAKVDELVRFTCQFGR
EEECCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA